CoV-GLUE | Mutations | Mutation
Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):
ORF | CodonNum | Mut | ORF1abMut | MutType | RefCodon | MutCodon | AACount | CodonCount | CodonProp | Genome Position |
S | 141 | L141F | nonsyn | ttG | ttT | 2249 | 2232 | 0.992441 | 21983-21985 |
Details of the mutation no within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):
ORF | CodonNum | Mut | RefCodon | MutCodon | CodonCount | AACount | Lineage | LineageCodonProp |
S | 141 | L141F | ttG | ttT | 2232 | 2249 | All | 0.000427 |
S | 141 | L141F | ttG | ttT | 949 | 950 | B.1.1.7 | 0.00085 |
S | 141 | L141F | ttG | ttT | 243 | 249 | AY.4 | 0.000378 |
S | 141 | L141F | ttG | ttT | 125 | 125 | B.1.2 | 0.001101 |
S | 141 | L141F | ttG | ttT | 99 | 105 | P.1 | 0.00156 |
S | 141 | L141F | ttG | ttT | 58 | 58 | A.23.1 | 0.040845 |
S | 141 | L141F | ttG | ttT | 56 | 56 | Q.1 | 0.007074 |
S | 141 | L141F | ttG | ttT | 52 | 52 | B.1.637 | 0.0038 |
S | 141 | L141F | ttG | ttT | 44 | 45 | B.1.617.2 | 0.000166 |
S | 141 | L141F | ttG | ttT | 43 | 43 | AY.25 | 0.000259 |
S | 141 | L141F | ttG | ttT | 30 | 30 | B.1.351 | 0.000892 |
S | 141 | L141F | ttG | ttT | 27 | 27 | AY.44 | 0.000164 |
S | 141 | L141F | ttG | ttT | 22 | 22 | B.1 | 0.000202 |
S | 141 | L141F | ttG | ttT | 20 | 20 | B.1.177 | 0.000263 |
S | 141 | L141F | ttG | ttT | 18 | 18 | AY.103 | 0.000112 |
S | 141 | L141F | ttG | ttT | 17 | 17 | AY.39.1 | 0.000673 |
S | 141 | L141F | ttG | ttT | 17 | 17 | B.1.1 | 0.000308 |
S | 141 | L141F | ttG | ttT | 16 | 16 | B.1.526 | 0.000376 |
S | 141 | L141F | ttG | ttT | 15 | 15 | AY.3 | 0.000149 |
S | 141 | L141F | ttG | ttT | 15 | 15 | B.1.221 | 0.001065 |
S | 141 | L141F | ttG | ttT | 13 | 13 | B.1.429 | 0.000306 |
S | 141 | L141F | ttG | ttT | 12 | 12 | B.1.427 | 0.000606 |
S | 141 | L141F | ttG | ttT | 11 | 11 | B.1.160 | 0.000343 |
S | 141 | L141F | ttG | ttT | 10 | 10 | AY.20 | 0.000389 |
S | 141 | L141F | ttG | ttT | 10 | 10 | AY.4.2 | 0.000217 |
S | 141 | L141F | ttG | ttT | 10 | 10 | AY.43 | 0.000044 |
S | 141 | L141F | ttG | ttT | 10 | 10 | B.1.258 | 0.000665 |
S | 141 | L141F | ttG | ttT | 9 | 9 | A.28 | 0.02381 |
S | 141 | L141F | ttG | ttT | 9 | 9 | AY.5 | 0.000186 |
S | 141 | L141F | ttG | ttT | 9 | 9 | P.1.6 | 0.01751 |
S | 141 | L141F | ttG | ttT | 8 | 8 | A.2.5 | 0.003992 |
S | 141 | L141F | ttG | ttT | 8 | 8 | Q.8 | 0.001319 |
S | 141 | L141F | ttG | ttT | 7 | 7 | AY.119 | 0.000247 |
S | 141 | L141F | ttG | ttT | 7 | 7 | B.1.525 | 0.000792 |
S | 141 | L141F | ttG | ttT | 6 | 6 | AY.54 | 0.000572 |
S | 141 | L141F | ttG | ttT | 6 | 6 | B.1.128 | 0.003812 |
S | 141 | L141F | ttG | ttT | 6 | 6 | B.1.486 | 0.666667 |
S | 141 | L141F | ttG | ttT | 5 | 5 | AY.120 | 0.000186 |
S | 141 | L141F | ttG | ttT | 5 | 5 | B.1.1.222 | 0.00102 |
S | 141 | L141F | ttG | ttT | 5 | 5 | B.1.351.2 | 0.001513 |
S | 141 | L141F | ttG | ttT | 5 | 5 | B.1.617.1 | 0.000645 |
S | 141 | L141F | ttG | ttT | 5 | 5 | B.1.621 | 0.000443 |
S | 141 | L141F | ttG | ttT | 5 | 5 | C.37 | 0.00058 |
S | 141 | L141F | ttG | ttT | 5 | 5 | P.1.15 | 0.001162 |
S | 141 | L141F | ttG | ttT | 4 | 4 | A.2.5.2 | 0.006289 |
S | 141 | L141F | ttG | ttT | 4 | 4 | AY.26 | 0.000113 |
S | 141 | L141F | ttG | ttT | 4 | 4 | AY.29.1 | 0.000882 |
S | 141 | L141F | ttG | ttT | 4 | 4 | AY.9.2 | 0.000147 |
S | 141 | L141F | ttG | ttT | 4 | 4 | AZ.6 | 0.033613 |
S | 141 | L141F | ttG | ttT | 4 | 4 | B.1.1.519 | 0.000159 |
S | 141 | L141F | ttG | ttT | 3 | 3 | 0.166667 | |
S | 141 | L141F | ttG | ttT | 3 | 3 | AY.27 | 0.000194 |
S | 141 | L141F | ttG | ttT | 3 | 3 | AY.39 | 0.000074 |
S | 141 | L141F | ttG | ttT | 3 | 3 | AY.93 | 0.000819 |
S | 141 | L141F | ttG | ttT | 3 | 3 | B.1.1.253 | 0.007519 |
S | 141 | L141F | ttG | ttT | 3 | 3 | B.1.594 | 0.09375 |
S | 141 | L141F | ttG | ttT | 3 | 3 | D.2 | 0.000225 |
S | 141 | L141F | ttG | ttT | 3 | 3 | P.1.12 | 0.001452 |
S | 141 | L141F | ttG | ttT | 2 | 2 | AY.118 | 0.000125 |
S | 141 | L141F | ttG | ttT | 2 | 2 | AY.14 | 0.000176 |
S | 141 | L141F | ttG | ttT | 2 | 2 | AY.23 | 0.000139 |
S | 141 | L141F | ttG | ttT | 2 | 2 | AY.29 | 0.000032 |
S | 141 | L141F | ttG | ttT | 2 | 2 | AY.3.1 | 0.000171 |
S | 141 | L141F | ttG | ttT | 2 | 2 | AY.42 | 0.00008 |
S | 141 | L141F | ttG | ttT | 2 | 2 | AY.55 | 0.001835 |
S | 141 | L141F | ttG | ttT | 2 | 2 | AY.56 | 0.00321 |
S | 141 | L141F | ttG | ttT | 2 | 2 | AY.73 | 0.001331 |
S | 141 | L141F | ttG | ttT | 2 | 2 | B.1.1.265 | 0.006309 |
S | 141 | L141F | ttG | ttT | 2 | 2 | B.1.1.284 | 0.000215 |
S | 141 | L141F | ttG | ttT | 2 | 2 | B.1.1.70 | 0.000682 |
S | 141 | L141F | ttG | ttT | 2 | 2 | B.1.177.16 | 0.001329 |
S | 141 | L141F | ttG | ttT | 2 | 2 | B.1.177.4 | 0.000422 |
S | 141 | L141F | ttG | ttT | 2 | 2 | B.1.243 | 0.000139 |
S | 141 | L141F | ttG | ttT | 2 | 2 | B.1.595 | 0.000522 |
S | 141 | L141F | ttG | ttT | 2 | 2 | B.1.621.1 | 0.001012 |
S | 141 | L141F | ttG | ttT | 2 | 2 | B.1.625 | 0.004706 |
S | 141 | L141F | ttG | ttT | 2 | 2 | P.1.1 | 0.000635 |
S | 141 | L141F | ttG | ttT | 2 | 2 | P.1.13 | 0.001797 |
S | 141 | L141F | ttG | ttT | 2 | 2 | P.1.4 | 0.001953 |
S | 141 | L141F | ttG | ttT | 1 | 2 | P.2 | 0.000187 |
S | 141 | L141F | ttG | ttT | 1 | 1 | A.2.5.1 | 0.004808 |
S | 141 | L141F | ttG | ttT | 1 | 1 | AA.5 | 0.016129 |
S | 141 | L141F | ttG | ttT | 1 | 1 | AY.102 | 0.000027 |
S | 141 | L141F | ttG | ttT | 1 | 1 | AY.108 | 0.001103 |
S | 141 | L141F | ttG | ttT | 1 | 1 | AY.110 | 0.000113 |
S | 141 | L141F | ttG | ttT | 1 | 1 | AY.116.1 | 0.000311 |
S | 141 | L141F | ttG | ttT | 1 | 1 | AY.117 | 0.000085 |
S | 141 | L141F | ttG | ttT | 1 | 1 | AY.31 | 0.018519 |
S | 141 | L141F | ttG | ttT | 1 | 1 | AY.34.1 | 0.00051 |
S | 141 | L141F | ttG | ttT | 1 | 1 | AY.35 | 0.000233 |
S | 141 | L141F | ttG | ttT | 1 | 1 | AY.36 | 0.000148 |
S | 141 | L141F | ttG | ttT | 1 | 1 | AY.4.5 | 0.000107 |
S | 141 | L141F | ttG | ttT | 1 | 1 | AY.46.4 | 0.000165 |
S | 141 | L141F | ttG | ttT | 1 | 1 | AY.51 | 0.000909 |
S | 141 | L141F | ttG | ttT | 1 | 1 | AY.84 | 0.000437 |
S | 141 | L141F | ttG | ttT | 1 | 1 | AY.92 | 0.000287 |
S | 141 | L141F | ttG | ttT | 1 | 1 | AY.97 | 0.001701 |
S | 141 | L141F | ttG | ttT | 1 | 1 | AY.98.1 | 0.000048 |
S | 141 | L141F | ttG | ttT | 1 | 1 | B | 0.000128 |
S | 141 | L141F | ttG | ttT | 1 | 1 | B.1.1.170 | 0.001247 |
S | 141 | L141F | ttG | ttT | 1 | 1 | B.1.1.192 | 0.002309 |
S | 141 | L141F | ttG | ttT | 1 | 1 | B.1.1.214 | 0.000055 |
S | 141 | L141F | ttG | ttT | 1 | 1 | B.1.1.216 | 0.00089 |
S | 141 | L141F | ttG | ttT | 1 | 1 | B.1.1.219 | 0.005 |
S | 141 | L141F | ttG | ttT | 1 | 1 | B.1.1.220 | 0.001859 |
S | 141 | L141F | ttG | ttT | 1 | 1 | B.1.1.241 | 0.00207 |
S | 141 | L141F | ttG | ttT | 1 | 1 | B.1.1.25 | 0.000569 |
S | 141 | L141F | ttG | ttT | 1 | 1 | B.1.1.291 | 0.000742 |
S | 141 | L141F | ttG | ttT | 1 | 1 | B.1.1.307 | 0.002532 |
S | 141 | L141F | ttG | ttT | 1 | 1 | B.1.1.318 | 0.000302 |
S | 141 | L141F | ttG | ttT | 1 | 1 | B.1.1.33 | 0.000421 |
S | 141 | L141F | ttG | ttT | 1 | 1 | B.1.1.335 | 0.012987 |
S | 141 | L141F | ttG | ttT | 1 | 1 | B.1.1.348 | 0.000796 |
S | 141 | L141F | ttG | ttT | 1 | 1 | B.1.1.378 | 0.007299 |
S | 141 | L141F | ttG | ttT | 1 | 1 | B.1.1.429 | 0.004608 |
S | 141 | L141F | ttG | ttT | 1 | 1 | B.1.1.434 | 0.000349 |
S | 141 | L141F | ttG | ttT | 1 | 1 | B.1.1.453 | 0.008475 |
S | 141 | L141F | ttG | ttT | 1 | 1 | B.1.1.63 | 0.000386 |
S | 141 | L141F | ttG | ttT | 1 | 1 | B.1.177.12 | 0.000152 |
S | 141 | L141F | ttG | ttT | 1 | 1 | B.1.177.35 | 0.000691 |
S | 141 | L141F | ttG | ttT | 1 | 1 | B.1.177.44 | 0.000519 |
S | 141 | L141F | ttG | ttT | 1 | 1 | B.1.177.50 | 0.004695 |
S | 141 | L141F | ttG | ttT | 1 | 1 | B.1.177.81 | 0.000189 |
S | 141 | L141F | ttG | ttT | 1 | 1 | B.1.177.9 | 0.001332 |
S | 141 | L141F | ttG | ttT | 1 | 1 | B.1.22 | 0.001318 |
S | 141 | L141F | ttG | ttT | 1 | 1 | B.1.234 | 0.000132 |
S | 141 | L141F | ttG | ttT | 1 | 1 | B.1.241 | 0.000812 |
S | 141 | L141F | ttG | ttT | 1 | 1 | B.1.258.17 | 0.000104 |
S | 141 | L141F | ttG | ttT | 1 | 1 | B.1.291 | 0.019231 |
S | 141 | L141F | ttG | ttT | 1 | 1 | B.1.311 | 0.000275 |
S | 141 | L141F | ttG | ttT | 1 | 1 | B.1.333 | 0.010526 |
S | 141 | L141F | ttG | ttT | 1 | 1 | B.1.349 | 0.000715 |
S | 141 | L141F | ttG | ttT | 1 | 1 | B.1.351.3 | 0.000876 |
S | 141 | L141F | ttG | ttT | 1 | 1 | B.1.36.10 | 0.004785 |
S | 141 | L141F | ttG | ttT | 1 | 1 | B.1.36.22 | 0.001208 |
S | 141 | L141F | ttG | ttT | 1 | 1 | B.1.36.31 | 0.001751 |
S | 141 | L141F | ttG | ttT | 1 | 1 | B.1.367 | 0.000792 |
S | 141 | L141F | ttG | ttT | 1 | 1 | B.1.389 | 0.001002 |
S | 141 | L141F | ttG | ttT | 1 | 1 | B.1.390 | 0.010638 |
S | 141 | L141F | ttG | ttT | 1 | 1 | B.1.400 | 0.000429 |
S | 141 | L141F | ttG | ttT | 1 | 1 | B.1.404 | 0.001302 |
S | 141 | L141F | ttG | ttT | 1 | 1 | B.1.416 | 0.001269 |
S | 141 | L141F | ttG | ttT | 1 | 1 | B.1.438.1 | 0.000107 |
S | 141 | L141F | ttG | ttT | 1 | 1 | B.1.465 | 0.003802 |
S | 141 | L141F | ttG | ttT | 1 | 1 | B.1.470 | 0.001404 |
S | 141 | L141F | ttG | ttT | 1 | 1 | B.1.488 | 0.2 |
S | 141 | L141F | ttG | ttT | 1 | 1 | B.1.495 | 0.009091 |
S | 141 | L141F | ttG | ttT | 1 | 1 | B.1.524 | 0.001406 |
S | 141 | L141F | ttG | ttT | 1 | 1 | B.1.539 | 0.017544 |
S | 141 | L141F | ttG | ttT | 1 | 1 | B.1.551 | 0.00129 |
S | 141 | L141F | ttG | ttT | 1 | 1 | B.1.564 | 0.000426 |
S | 141 | L141F | ttG | ttT | 1 | 1 | B.1.582 | 0.000491 |
S | 141 | L141F | ttG | ttT | 1 | 1 | B.1.596 | 0.000087 |
S | 141 | L141F | ttG | ttT | 1 | 1 | B.1.619.1 | 0.000641 |
S | 141 | L141F | ttG | ttT | 1 | 1 | B.1.9 | 0.006173 |
S | 141 | L141F | ttG | ttT | 1 | 1 | B.23 | 0.002924 |
S | 141 | L141F | ttG | ttT | 1 | 1 | B.31 | 0.003731 |
S | 141 | L141F | ttG | ttT | 1 | 1 | B.55 | 0.00295 |
S | 141 | L141F | ttG | ttT | 1 | 1 | B.58 | 0.010204 |
S | 141 | L141F | ttG | ttT | 1 | 1 | C.18 | 0.002591 |
S | 141 | L141F | ttG | ttT | 1 | 1 | C.36 | 0.000911 |
S | 141 | L141F | ttG | ttT | 1 | 1 | P.1.11 | 0.010204 |
S | 141 | L141F | ttG | ttT | 1 | 1 | P.1.14 | 0.000048 |
S | 141 | L141F | ttG | ttT | 1 | 1 | P.1.17 | 0.000162 |
S | 141 | L141F | ttG | ttT | 1 | 1 | P.1.2 | 0.001156 |
S | 141 | L141F | ttG | ttT | 1 | 1 | P.1.7 | 0.000319 |
S | 141 | L141F | ttG | ttT | 1 | 1 | P.3 | 0.001595 |
S | 141 | L141F | ttG | ttT | 1 | 1 | P.6 | 0.003145 |
S | 141 | L141F | ttG | ttT | 1 | 1 | Q.3 | 0.000145 |
CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk
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