CoV-GLUE | Mutations | Mutation
Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):
ORF | CodonNum | Mut | ORF1abMut | MutType | RefCodon | MutCodon | AACount | CodonCount | CodonProp | Genome Position |
S | 1238 | T1238T | syn | acC | acT | 15737 | 7974 | 0.506704 | 25274-25276 |
Details of the mutation no within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):
ORF | CodonNum | Mut | RefCodon | MutCodon | CodonCount | AACount | Lineage | LineageCodonProp |
S | 1238 | T1238T | acC | acT | 7974 | 15737 | All | 0.001525 |
S | 1238 | T1238T | acC | acT | 2678 | 2763 | B.1.1.7 | 0.002397 |
S | 1238 | T1238T | acC | acT | 1343 | 1400 | AY.4 | 0.00209 |
S | 1238 | T1238T | acC | acT | 396 | 396 | R.1 | 0.035644 |
S | 1238 | T1238T | acC | acT | 331 | 332 | B.1.617.1 | 0.042688 |
S | 1238 | T1238T | acC | acT | 288 | 295 | AY.119 | 0.010169 |
S | 1238 | T1238T | acC | acT | 199 | 222 | AY.103 | 0.001236 |
S | 1238 | T1238T | acC | acT | 201 | 201 | B.1.1.214 | 0.011147 |
S | 1238 | T1238T | acC | acT | 154 | 185 | B.1.617.2 | 0.00058 |
S | 1238 | T1238T | acC | acT | 154 | 171 | B.1.2 | 0.001356 |
S | 1238 | T1238T | acC | acT | 88 | 161 | AY.3 | 0.000875 |
S | 1238 | T1238T | acC | acT | 72 | 95 | AY.25 | 0.000433 |
S | 1238 | T1238T | acC | acT | 92 | 95 | P.1 | 0.001449 |
S | 1238 | T1238T | acC | acT | 76 | 94 | B.1 | 0.000696 |
S | 1238 | T1238T | acC | acT | 90 | 93 | B.1.429 | 0.002118 |
S | 1238 | T1238T | acC | acT | 88 | 88 | AY.18 | 0.888889 |
S | 1238 | T1238T | acC | acT | 72 | 85 | B.1.1 | 0.001306 |
S | 1238 | T1238T | acC | acT | 63 | 75 | AY.43 | 0.000279 |
S | 1238 | T1238T | acC | acT | 66 | 71 | AY.44 | 0.000402 |
S | 1238 | T1238T | acC | acT | 61 | 61 | B.1.627 | 0.123232 |
S | 1238 | T1238T | acC | acT | 58 | 59 | AY.74 | 0.006708 |
S | 1238 | T1238T | acC | acT | 37 | 59 | B.1.177 | 0.000487 |
S | 1238 | T1238T | acC | acT | 59 | 59 | B.1.177.86 | 0.010824 |
S | 1238 | T1238T | acC | acT | 5 | 53 | AY.47 | 0.000156 |
S | 1238 | T1238T | acC | acT | 47 | 47 | B.1.160.21 | 0.959184 |
S | 1238 | T1238T | acC | acT | 46 | 46 | B.1.311 | 0.01263 |
S | 1238 | T1238T | acC | acT | 41 | 41 | AY.98.1 | 0.001986 |
S | 1238 | T1238T | acC | acT | 13 | 39 | B.1.427 | 0.000656 |
S | 1238 | T1238T | acC | acT | 36 | 36 | B.1.609 | 0.017258 |
S | 1238 | T1238T | acC | acT | 33 | 35 | AY.75 | 0.001849 |
S | 1238 | T1238T | acC | acT | 35 | 35 | B.1.1.519 | 0.00139 |
S | 1238 | T1238T | acC | acT | 34 | 35 | B.1.526 | 0.000799 |
S | 1238 | T1238T | acC | acT | 35 | 35 | C.36.3 | 0.019853 |
S | 1238 | T1238T | acC | acT | 33 | 33 | B.1.619.1 | 0.021167 |
S | 1238 | T1238T | acC | acT | 9 | 32 | AY.14 | 0.000792 |
S | 1238 | T1238T | acC | acT | 27 | 27 | B.1.160 | 0.000842 |
S | 1238 | T1238T | acC | acT | 26 | 26 | B.1.177.32 | 0.035088 |
S | 1238 | T1238T | acC | acT | 24 | 24 | B.1.139 | 0.017595 |
S | 1238 | T1238T | acC | acT | 24 | 24 | Q.3 | 0.003481 |
S | 1238 | T1238T | acC | acT | 22 | 23 | AY.42 | 0.000885 |
S | 1238 | T1238T | acC | acT | 19 | 23 | B.1.36 | 0.002772 |
S | 1238 | T1238T | acC | acT | 1 | 22 | AY.27 | 0.000065 |
S | 1238 | T1238T | acC | acT | 21 | 21 | AY.120.1 | 0.006742 |
S | 1238 | T1238T | acC | acT | 21 | 21 | B.1.177.81 | 0.003976 |
S | 1238 | T1238T | acC | acT | 19 | 19 | AY.20 | 0.000738 |
S | 1238 | T1238T | acC | acT | 16 | 19 | B.1.351 | 0.000476 |
S | 1238 | T1238T | acC | acT | 11 | 18 | AY.4.2 | 0.000239 |
S | 1238 | T1238T | acC | acT | 17 | 17 | AY.117 | 0.001437 |
S | 1238 | T1238T | acC | acT | 16 | 17 | AY.39 | 0.000395 |
S | 1238 | T1238T | acC | acT | 16 | 17 | AY.5 | 0.00033 |
S | 1238 | T1238T | acC | acT | 17 | 17 | AY.6 | 0.000699 |
S | 1238 | T1238T | acC | acT | 16 | 16 | AY.70 | 0.003336 |
S | 1238 | T1238T | acC | acT | 16 | 16 | AY.85 | 0.006835 |
S | 1238 | T1238T | acC | acT | 16 | 16 | B.1.596 | 0.001394 |
S | 1238 | T1238T | acC | acT | 16 | 16 | C.37 | 0.001857 |
S | 1238 | T1238T | acC | acT | 15 | 15 | B.1.1.434 | 0.005228 |
S | 1238 | T1238T | acC | acT | 11 | 15 | B.1.243 | 0.000765 |
S | 1238 | T1238T | acC | acT | 15 | 15 | B.1.517 | 0.006405 |
S | 1238 | T1238T | acC | acT | 15 | 15 | P.1.15 | 0.003485 |
S | 1238 | T1238T | acC | acT | 12 | 14 | AY.102 | 0.000318 |
S | 1238 | T1238T | acC | acT | 14 | 14 | P.1.14 | 0.000669 |
S | 1238 | T1238T | acC | acT | 12 | 13 | AY.100 | 0.000552 |
S | 1238 | T1238T | acC | acT | 13 | 13 | AY.16 | 0.004935 |
S | 1238 | T1238T | acC | acT | 13 | 13 | AY.4.2.1 | 0.001937 |
S | 1238 | T1238T | acC | acT | 11 | 12 | AY.118 | 0.000689 |
S | 1238 | T1238T | acC | acT | 10 | 12 | AY.29 | 0.000158 |
S | 1238 | T1238T | acC | acT | 12 | 12 | AY.9 | 0.000811 |
S | 1238 | T1238T | acC | acT | 11 | 12 | B.1.466.2 | 0.004304 |
S | 1238 | T1238T | acC | acT | 11 | 12 | B.1.470 | 0.015449 |
S | 1238 | T1238T | acC | acT | 9 | 11 | AY.99.2 | 0.000829 |
S | 1238 | T1238T | acC | acT | 3 | 10 | B.1.1.222 | 0.000612 |
S | 1238 | T1238T | acC | acT | 10 | 10 | B.1.1.512 | 0.285714 |
S | 1238 | T1238T | acC | acT | 9 | 10 | B.1.599 | 0.032847 |
S | 1238 | T1238T | acC | acT | 9 | 10 | B.1.621 | 0.000797 |
S | 1238 | T1238T | acC | acT | 7 | 9 | AY.98 | 0.000553 |
S | 1238 | T1238T | acC | acT | 9 | 9 | B.1.575 | 0.002731 |
S | 1238 | T1238T | acC | acT | 8 | 8 | AY.5.4 | 0.002214 |
S | 1238 | T1238T | acC | acT | 8 | 8 | B.1.438.1 | 0.000858 |
S | 1238 | T1238T | acC | acT | 7 | 8 | B.1.623 | 0.003755 |
S | 1238 | T1238T | acC | acT | 8 | 8 | Q.1 | 0.001011 |
S | 1238 | T1238T | acC | acT | 7 | 7 | B.1.36.29 | 0.003621 |
S | 1238 | T1238T | acC | acT | 7 | 7 | B.1.577 | 0.004811 |
S | 1238 | T1238T | acC | acT | 6 | 6 | AY.33 | 0.000401 |
S | 1238 | T1238T | acC | acT | 6 | 6 | AY.34 | 0.000582 |
S | 1238 | T1238T | acC | acT | 6 | 6 | AY.5.3 | 0.002024 |
S | 1238 | T1238T | acC | acT | 6 | 6 | B.1.1.28 | 0.001867 |
S | 1238 | T1238T | acC | acT | 6 | 6 | B.1.240 | 0.001293 |
S | 1238 | T1238T | acC | acT | 6 | 6 | B.1.258 | 0.000399 |
S | 1238 | T1238T | acC | acT | 6 | 6 | B.1.403 | 0.019608 |
S | 1238 | T1238T | acC | acT | 5 | 6 | B.1.637 | 0.000365 |
S | 1238 | T1238T | acC | acT | 5 | 5 | AY.120 | 0.000186 |
S | 1238 | T1238T | acC | acT | 3 | 5 | AY.3.1 | 0.000256 |
S | 1238 | T1238T | acC | acT | 3 | 5 | AY.9.2 | 0.00011 |
S | 1238 | T1238T | acC | acT | 5 | 5 | B.1.1.39 | 0.002548 |
S | 1238 | T1238T | acC | acT | 5 | 5 | B.1.1.50 | 0.003394 |
S | 1238 | T1238T | acC | acT | 5 | 5 | B.1.177.18 | 0.0058 |
S | 1238 | T1238T | acC | acT | 3 | 5 | B.1.525 | 0.000339 |
S | 1238 | T1238T | acC | acT | 4 | 4 | AY.51 | 0.003636 |
S | 1238 | T1238T | acC | acT | 4 | 4 | AY.88 | 0.003537 |
S | 1238 | T1238T | acC | acT | 3 | 4 | B | 0.000383 |
S | 1238 | T1238T | acC | acT | 4 | 4 | B.1.1.303 | 0.01105 |
S | 1238 | T1238T | acC | acT | 4 | 4 | B.1.177.43 | 0.005908 |
S | 1238 | T1238T | acC | acT | 4 | 4 | B.1.177.60 | 0.000874 |
S | 1238 | T1238T | acC | acT | 4 | 4 | B.1.595 | 0.001044 |
S | 1238 | T1238T | acC | acT | 4 | 4 | B.1.78 | 0.034188 |
S | 1238 | T1238T | acC | acT | 4 | 4 | D.2 | 0.0003 |
S | 1238 | T1238T | acC | acT | 4 | 4 | P.1.10 | 0.001078 |
S | 1238 | T1238T | acC | acT | 2 | 3 | AD.2 | 0.000438 |
S | 1238 | T1238T | acC | acT | 1 | 3 | AY.23 | 0.00007 |
S | 1238 | T1238T | acC | acT | 3 | 3 | AY.26 | 0.000085 |
S | 1238 | T1238T | acC | acT | 3 | 3 | AY.4.1 | 0.002212 |
S | 1238 | T1238T | acC | acT | 2 | 3 | AY.61 | 0.00021 |
S | 1238 | T1238T | acC | acT | 3 | 3 | AY.86 | 0.00249 |
S | 1238 | T1238T | acC | acT | 3 | 3 | AY.9.1 | 0.000251 |
S | 1238 | T1238T | acC | acT | 3 | 3 | AY.97 | 0.005102 |
S | 1238 | T1238T | acC | acT | 3 | 3 | B.1.1.1 | 0.00098 |
S | 1238 | T1238T | acC | acT | 3 | 3 | B.1.1.220 | 0.005576 |
S | 1238 | T1238T | acC | acT | 3 | 3 | B.1.1.280 | 0.009259 |
S | 1238 | T1238T | acC | acT | 3 | 3 | B.1.1.33 | 0.001263 |
S | 1238 | T1238T | acC | acT | 3 | 3 | B.1.1.70 | 0.001023 |
S | 1238 | T1238T | acC | acT | 3 | 3 | B.1.416 | 0.003807 |
S | 1238 | T1238T | acC | acT | 1 | 3 | B.1.551 | 0.00129 |
S | 1238 | T1238T | acC | acT | 3 | 3 | B.30 | 0.044118 |
S | 1238 | T1238T | acC | acT | 3 | 3 | C.1 | 0.007177 |
S | 1238 | T1238T | acC | acT | 3 | 3 | Q.8 | 0.000495 |
S | 1238 | T1238T | acC | acT | 1 | 2 | 0.055556 | |
S | 1238 | T1238T | acC | acT | 2 | 2 | AJ.1 | 0.090909 |
S | 1238 | T1238T | acC | acT | 2 | 2 | AY.111 | 0.000366 |
S | 1238 | T1238T | acC | acT | 2 | 2 | AY.12 | 0.000632 |
S | 1238 | T1238T | acC | acT | 1 | 2 | AY.30 | 0.000396 |
S | 1238 | T1238T | acC | acT | 2 | 2 | AY.32 | 0.001065 |
S | 1238 | T1238T | acC | acT | 1 | 2 | AY.46 | 0.000104 |
S | 1238 | T1238T | acC | acT | 2 | 2 | AY.46.6 | 0.000144 |
S | 1238 | T1238T | acC | acT | 1 | 2 | AY.55 | 0.000917 |
S | 1238 | T1238T | acC | acT | 2 | 2 | AY.56 | 0.00321 |
S | 1238 | T1238T | acC | acT | 2 | 2 | AY.58 | 0.001815 |
S | 1238 | T1238T | acC | acT | 2 | 2 | AY.64 | 0.00119 |
S | 1238 | T1238T | acC | acT | 2 | 2 | AY.77 | 0.002255 |
S | 1238 | T1238T | acC | acT | 2 | 2 | AY.92 | 0.000575 |
S | 1238 | T1238T | acC | acT | 2 | 2 | B.1.1.174 | 0.006757 |
S | 1238 | T1238T | acC | acT | 2 | 2 | B.1.1.326 | 0.003521 |
S | 1238 | T1238T | acC | acT | 2 | 2 | B.1.1.37 | 0.000386 |
S | 1238 | T1238T | acC | acT | 1 | 2 | B.1.1.389 | 0.006061 |
S | 1238 | T1238T | acC | acT | 2 | 2 | B.1.1.63 | 0.000772 |
S | 1238 | T1238T | acC | acT | 2 | 2 | B.1.111 | 0.00235 |
S | 1238 | T1238T | acC | acT | 2 | 2 | B.1.161 | 0.034483 |
S | 1238 | T1238T | acC | acT | 2 | 2 | B.1.177.17 | 0.001642 |
S | 1238 | T1238T | acC | acT | 2 | 2 | B.1.177.7 | 0.00033 |
S | 1238 | T1238T | acC | acT | 2 | 2 | B.1.214 | 0.007326 |
S | 1238 | T1238T | acC | acT | 1 | 2 | B.1.221 | 0.000071 |
S | 1238 | T1238T | acC | acT | 2 | 2 | B.1.234 | 0.000264 |
S | 1238 | T1238T | acC | acT | 2 | 2 | B.1.36.18 | 0.00084 |
S | 1238 | T1238T | acC | acT | 2 | 2 | B.1.367 | 0.001585 |
S | 1238 | T1238T | acC | acT | 1 | 2 | B.1.565 | 0.00081 |
S | 1238 | T1238T | acC | acT | 2 | 2 | B.1.589 | 0.015152 |
S | 1238 | T1238T | acC | acT | 2 | 2 | B.6 | 0.00182 |
S | 1238 | T1238T | acC | acT | 1 | 2 | C.36 | 0.000911 |
S | 1238 | T1238T | acC | acT | 2 | 2 | N.3 | 0.011628 |
S | 1238 | T1238T | acC | acT | 2 | 2 | P.1.12 | 0.000968 |
S | 1238 | T1238T | acC | acT | 2 | 2 | P.1.2 | 0.002312 |
S | 1238 | T1238T | acC | acT | 1 | 2 | P.2 | 0.000187 |
S | 1238 | T1238T | acC | acT | 1 | 1 | A.23.1 | 0.000704 |
S | 1238 | T1238T | acC | acT | 1 | 1 | A.5 | 0.001923 |
S | 1238 | T1238T | acC | acT | 1 | 1 | AE.8 | 0.000489 |
S | 1238 | T1238T | acC | acT | 1 | 1 | AU.2 | 0.002421 |
S | 1238 | T1238T | acC | acT | 1 | 1 | AY.106 | 0.000335 |
S | 1238 | T1238T | acC | acT | 1 | 1 | AY.11 | 0.001339 |
S | 1238 | T1238T | acC | acT | 1 | 1 | AY.113 | 0.000142 |
S | 1238 | T1238T | acC | acT | 1 | 1 | AY.115 | 0.005208 |
S | 1238 | T1238T | acC | acT | 1 | 1 | AY.116 | 0.000287 |
S | 1238 | T1238T | acC | acT | 1 | 1 | AY.121 | 0.000135 |
S | 1238 | T1238T | acC | acT | 1 | 1 | AY.13 | 0.000161 |
S | 1238 | T1238T | acC | acT | 1 | 1 | AY.2 | 0.000356 |
S | 1238 | T1238T | acC | acT | 1 | 1 | AY.21 | 0.001898 |
S | 1238 | T1238T | acC | acT | 1 | 1 | AY.28 | 0.00189 |
S | 1238 | T1238T | acC | acT | 1 | 1 | AY.29.1 | 0.000221 |
S | 1238 | T1238T | acC | acT | 1 | 1 | AY.36 | 0.000148 |
S | 1238 | T1238T | acC | acT | 1 | 1 | AY.4.5 | 0.000107 |
S | 1238 | T1238T | acC | acT | 1 | 1 | AY.46.1 | 0.001027 |
S | 1238 | T1238T | acC | acT | 1 | 1 | AY.46.2 | 0.000635 |
S | 1238 | T1238T | acC | acT | 1 | 1 | AY.48 | 0.000465 |
S | 1238 | T1238T | acC | acT | 1 | 1 | AY.49 | 0.003195 |
S | 1238 | T1238T | acC | acT | 1 | 1 | AY.53 | 0.000288 |
S | 1238 | T1238T | acC | acT | 1 | 1 | AY.54 | 0.000095 |
S | 1238 | T1238T | acC | acT | 1 | 1 | AY.65 | 0.000533 |
S | 1238 | T1238T | acC | acT | 1 | 1 | AY.67 | 0.000464 |
S | 1238 | T1238T | acC | acT | 1 | 1 | AY.7 | 0.000196 |
S | 1238 | T1238T | acC | acT | 1 | 1 | AY.71 | 0.000475 |
S | 1238 | T1238T | acC | acT | 1 | 1 | AY.79 | 0.001211 |
S | 1238 | T1238T | acC | acT | 1 | 1 | AY.91 | 0.00073 |
S | 1238 | T1238T | acC | acT | 1 | 1 | AY.93 | 0.000273 |
S | 1238 | T1238T | acC | acT | 1 | 1 | B.1.1.153 | 0.001095 |
S | 1238 | T1238T | acC | acT | 1 | 1 | B.1.1.163 | 0.007634 |
S | 1238 | T1238T | acC | acT | 1 | 1 | B.1.1.216 | 0.00089 |
S | 1238 | T1238T | acC | acT | 1 | 1 | B.1.1.231 | 0.003096 |
S | 1238 | T1238T | acC | acT | 1 | 1 | B.1.1.240 | 0.004695 |
S | 1238 | T1238T | acC | acT | 1 | 1 | B.1.1.241 | 0.00207 |
S | 1238 | T1238T | acC | acT | 1 | 1 | B.1.1.243 | 0.004082 |
S | 1238 | T1238T | acC | acT | 1 | 1 | B.1.1.284 | 0.000107 |
S | 1238 | T1238T | acC | acT | 1 | 1 | B.1.1.301 | 0.001179 |
S | 1238 | T1238T | acC | acT | 1 | 1 | B.1.1.312 | 0.001912 |
S | 1238 | T1238T | acC | acT | 1 | 1 | B.1.1.368 | 0.003086 |
S | 1238 | T1238T | acC | acT | 1 | 1 | B.1.1.370 | 0.012658 |
S | 1238 | T1238T | acC | acT | 1 | 1 | B.1.1.397 | 0.002252 |
S | 1238 | T1238T | acC | acT | 1 | 1 | B.1.1.486 | 0.001577 |
S | 1238 | T1238T | acC | acT | 1 | 1 | B.1.1.52 | 0.012195 |
S | 1238 | T1238T | acC | acT | 1 | 1 | B.1.1.98 | 0.018519 |
S | 1238 | T1238T | acC | acT | 1 | 1 | B.1.110 | 0.004525 |
S | 1238 | T1238T | acC | acT | 1 | 1 | B.1.120 | 0.007692 |
S | 1238 | T1238T | acC | acT | 1 | 1 | B.1.128 | 0.000635 |
S | 1238 | T1238T | acC | acT | 1 | 1 | B.1.158 | 0.02381 |
S | 1238 | T1238T | acC | acT | 1 | 1 | B.1.160.20 | 0.008929 |
S | 1238 | T1238T | acC | acT | 1 | 1 | B.1.177.24 | 0.001295 |
S | 1238 | T1238T | acC | acT | 1 | 1 | B.1.177.4 | 0.000211 |
S | 1238 | T1238T | acC | acT | 1 | 1 | B.1.177.52 | 0.001757 |
S | 1238 | T1238T | acC | acT | 1 | 1 | B.1.177.54 | 0.000606 |
S | 1238 | T1238T | acC | acT | 1 | 1 | B.1.177.61 | 0.043478 |
S | 1238 | T1238T | acC | acT | 1 | 1 | B.1.232 | 0.000537 |
S | 1238 | T1238T | acC | acT | 1 | 1 | B.1.236 | 0.002053 |
S | 1238 | T1238T | acC | acT | 1 | 1 | B.1.237 | 0.004975 |
S | 1238 | T1238T | acC | acT | 1 | 1 | B.1.239 | 0.001221 |
S | 1238 | T1238T | acC | acT | 1 | 1 | B.1.241 | 0.000812 |
S | 1238 | T1238T | acC | acT | 1 | 1 | B.1.251 | 0.021739 |
S | 1238 | T1238T | acC | acT | 1 | 1 | B.1.258.11 | 0.000396 |
S | 1238 | T1238T | acC | acT | 1 | 1 | B.1.258.17 | 0.000104 |
S | 1238 | T1238T | acC | acT | 1 | 1 | B.1.265 | 0.001271 |
S | 1238 | T1238T | acC | acT | 1 | 1 | B.1.281 | 0.021739 |
S | 1238 | T1238T | acC | acT | 1 | 1 | B.1.332 | 0.003497 |
S | 1238 | T1238T | acC | acT | 1 | 1 | B.1.341 | 0.022727 |
S | 1238 | T1238T | acC | acT | 1 | 1 | B.1.349 | 0.000715 |
S | 1238 | T1238T | acC | acT | 1 | 1 | B.1.369 | 0.000285 |
S | 1238 | T1238T | acC | acT | 1 | 1 | B.1.499 | 0.00105 |
S | 1238 | T1238T | acC | acT | 1 | 1 | B.1.503 | 0.002488 |
S | 1238 | T1238T | acC | acT | 1 | 1 | B.1.540 | 0.009709 |
S | 1238 | T1238T | acC | acT | 1 | 1 | B.31 | 0.003731 |
S | 1238 | T1238T | acC | acT | 1 | 1 | B.61 | 0.005747 |
S | 1238 | T1238T | acC | acT | 1 | 1 | P.1.7 | 0.000319 |
S | 1238 | T1238T | acC | acT | 1 | 1 | Q.7 | 0.001111 |
S | 1238 | T1238T | acC | acT | 1 | 1 | W.4 | 0.001351 |
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CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk
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