CoV-GLUE | Mutations | Mutation
CoV-GLUE Mutation: ORF = S : CodonNum = 1073 & Codon = aaC
Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):
| ORF | CodonNum | Mut | ORF1abMut | MutType | RefCodon | MutCodon | AACount | CodonCount | CodonProp | Genome Position |
| S | 1073 | K1073N | nonsyn | aaG | aaC | 7685 | 3162 | 0.411451 | 24779-24781 |
Details of the mutation no within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):
| ORF | CodonNum | Mut | RefCodon | MutCodon | CodonCount | AACount | Lineage | LineageCodonProp |
| S | 1073 | K1073N | aaG | aaC | 3162 | 7685 | All | 0.000605 |
| S | 1073 | K1073N | aaG | aaC | 1826 | 1834 | AY.39 | 0.045123 |
| S | 1073 | K1073N | aaG | aaC | 646 | 646 | AY.39.2 | 0.995378 |
| S | 1073 | K1073N | aaG | aaC | 43 | 531 | AY.4 | 0.000067 |
| S | 1073 | K1073N | aaG | aaC | 25 | 489 | B.1.1.7 | 0.000022 |
| S | 1073 | K1073N | aaG | aaC | 209 | 395 | B.1.617.2 | 0.000787 |
| S | 1073 | K1073N | aaG | aaC | 36 | 169 | AY.43 | 0.000159 |
| S | 1073 | K1073N | aaG | aaC | 16 | 130 | AY.44 | 0.000097 |
| S | 1073 | K1073N | aaG | aaC | 4 | 123 | AY.3 | 0.00004 |
| S | 1073 | K1073N | aaG | aaC | 2 | 111 | AY.29 | 0.000032 |
| S | 1073 | K1073N | aaG | aaC | 8 | 95 | B.1 | 0.000073 |
| S | 1073 | K1073N | aaG | aaC | 11 | 93 | B.1.2 | 0.000097 |
| S | 1073 | K1073N | aaG | aaC | 17 | 86 | P.1 | 0.000268 |
| S | 1073 | K1073N | aaG | aaC | 15 | 79 | B.1.177 | 0.000198 |
| S | 1073 | K1073N | aaG | aaC | 26 | 69 | AY.25 | 0.000156 |
| S | 1073 | K1073N | aaG | aaC | 1 | 64 | B.1.526 | 0.000024 |
| S | 1073 | K1073N | aaG | aaC | 11 | 58 | AY.103 | 0.000068 |
| S | 1073 | K1073N | aaG | aaC | 40 | 43 | B.1.243 | 0.002783 |
| S | 1073 | K1073N | aaG | aaC | 35 | 41 | AY.39.1 | 0.001386 |
| S | 1073 | K1073N | aaG | aaC | 11 | 38 | B.1.1 | 0.0002 |
| S | 1073 | K1073N | aaG | aaC | 11 | 33 | B.1.427 | 0.000555 |
| S | 1073 | K1073N | aaG | aaC | 2 | 29 | AY.46.6 | 0.000144 |
| S | 1073 | K1073N | aaG | aaC | 20 | 29 | B.1.429 | 0.000471 |
| S | 1073 | K1073N | aaG | aaC | 5 | 26 | AY.100 | 0.00023 |
| S | 1073 | K1073N | aaG | aaC | 6 | 23 | P.1.14 | 0.000287 |
| S | 1073 | K1073N | aaG | aaC | 11 | 21 | AY.102 | 0.000292 |
| S | 1073 | K1073N | aaG | aaC | 8 | 20 | AY.5 | 0.000165 |
| S | 1073 | K1073N | aaG | aaC | 1 | 17 | B.1.36 | 0.000146 |
| S | 1073 | K1073N | aaG | aaC | 5 | 16 | AY.53 | 0.001438 |
| S | 1073 | K1073N | aaG | aaC | 2 | 16 | B.1.1.519 | 0.000079 |
| S | 1073 | K1073N | aaG | aaC | 1 | 14 | AY.46 | 0.000104 |
| S | 1073 | K1073N | aaG | aaC | 8 | 12 | AY.87 | 0.006661 |
| S | 1073 | K1073N | aaG | aaC | 4 | 11 | B.1.177.73 | 0.002265 |
| S | 1073 | K1073N | aaG | aaC | 1 | 11 | C.37 | 0.000116 |
| S | 1073 | K1073N | aaG | aaC | 1 | 10 | AY.62 | 0.000436 |
| S | 1073 | K1073N | aaG | aaC | 6 | 9 | AY.119 | 0.000212 |
| S | 1073 | K1073N | aaG | aaC | 4 | 9 | AY.23 | 0.000279 |
| S | 1073 | K1073N | aaG | aaC | 1 | 9 | AY.26 | 0.000028 |
| S | 1073 | K1073N | aaG | aaC | 2 | 9 | B.1.258 | 0.000133 |
| S | 1073 | K1073N | aaG | aaC | 3 | 8 | AY.120 | 0.000112 |
| S | 1073 | K1073N | aaG | aaC | 4 | 8 | AY.42 | 0.000161 |
| S | 1073 | K1073N | aaG | aaC | 1 | 7 | AY.20 | 0.000039 |
| S | 1073 | K1073N | aaG | aaC | 7 | 7 | B.1.1.192 | 0.016166 |
| S | 1073 | K1073N | aaG | aaC | 1 | 6 | AY.61 | 0.000105 |
| S | 1073 | K1073N | aaG | aaC | 1 | 6 | AY.9.2 | 0.000037 |
| S | 1073 | K1073N | aaG | aaC | 2 | 5 | A.2.5 | 0.000998 |
| S | 1073 | K1073N | aaG | aaC | 3 | 5 | AY.110 | 0.000338 |
| S | 1073 | K1073N | aaG | aaC | 1 | 5 | AY.117 | 0.000085 |
| S | 1073 | K1073N | aaG | aaC | 2 | 5 | B.1.177.86 | 0.000367 |
| S | 1073 | K1073N | aaG | aaC | 1 | 5 | Q.1 | 0.000126 |
| S | 1073 | K1073N | aaG | aaC | 1 | 4 | AY.105 | 0.000643 |
| S | 1073 | K1073N | aaG | aaC | 1 | 4 | AY.114 | 0.000231 |
| S | 1073 | K1073N | aaG | aaC | 4 | 4 | AY.16 | 0.001519 |
| S | 1073 | K1073N | aaG | aaC | 1 | 4 | AY.16.1 | 0.00047 |
| S | 1073 | K1073N | aaG | aaC | 2 | 4 | AY.24 | 0.000862 |
| S | 1073 | K1073N | aaG | aaC | 2 | 4 | AY.45 | 0.000243 |
| S | 1073 | K1073N | aaG | aaC | 2 | 4 | AY.75 | 0.000112 |
| S | 1073 | K1073N | aaG | aaC | 1 | 3 | AY.1 | 0.000396 |
| S | 1073 | K1073N | aaG | aaC | 2 | 3 | AY.36 | 0.000296 |
| S | 1073 | K1073N | aaG | aaC | 1 | 3 | AY.41 | 0.000294 |
| S | 1073 | K1073N | aaG | aaC | 1 | 3 | AY.5.3 | 0.000337 |
| S | 1073 | K1073N | aaG | aaC | 1 | 3 | AY.54 | 0.000095 |
| S | 1073 | K1073N | aaG | aaC | 1 | 3 | AY.98 | 0.000079 |
| S | 1073 | K1073N | aaG | aaC | 1 | 3 | AY.99.2 | 0.000092 |
| S | 1073 | K1073N | aaG | aaC | 3 | 3 | B.1.609 | 0.001438 |
| S | 1073 | K1073N | aaG | aaC | 1 | 3 | D.2 | 0.000075 |
| S | 1073 | K1073N | aaG | aaC | 1 | 2 | AY.107 | 0.000466 |
| S | 1073 | K1073N | aaG | aaC | 1 | 2 | AY.108 | 0.001103 |
| S | 1073 | K1073N | aaG | aaC | 1 | 2 | AY.3.1 | 0.000085 |
| S | 1073 | K1073N | aaG | aaC | 1 | 2 | AY.47 | 0.000031 |
| S | 1073 | K1073N | aaG | aaC | 1 | 2 | AY.6 | 0.000041 |
| S | 1073 | K1073N | aaG | aaC | 1 | 2 | AY.92 | 0.000287 |
| S | 1073 | K1073N | aaG | aaC | 2 | 2 | B.1.232 | 0.001075 |
| S | 1073 | K1073N | aaG | aaC | 2 | 2 | B.1.36.16 | 0.002849 |
| S | 1073 | K1073N | aaG | aaC | 1 | 2 | B.1.391 | 0.001127 |
| S | 1073 | K1073N | aaG | aaC | 2 | 2 | B.29 | 0.007018 |
| S | 1073 | K1073N | aaG | aaC | 1 | 1 | A.2.4 | 0.003367 |
| S | 1073 | K1073N | aaG | aaC | 1 | 1 | A.23.1 | 0.000704 |
| S | 1073 | K1073N | aaG | aaC | 1 | 1 | AY.104 | 0.001984 |
| S | 1073 | K1073N | aaG | aaC | 1 | 1 | AY.60 | 0.000938 |
| S | 1073 | K1073N | aaG | aaC | 1 | 1 | AY.65 | 0.000533 |
| S | 1073 | K1073N | aaG | aaC | 1 | 1 | AY.68 | 0.000274 |
| S | 1073 | K1073N | aaG | aaC | 1 | 1 | AY.91 | 0.00073 |
| S | 1073 | K1073N | aaG | aaC | 1 | 1 | AY.99 | 0.001049 |
| S | 1073 | K1073N | aaG | aaC | 1 | 1 | B | 0.000128 |
| S | 1073 | K1073N | aaG | aaC | 1 | 1 | B.1.1.263 | 0.001558 |
| S | 1073 | K1073N | aaG | aaC | 1 | 1 | B.1.1.306 | 0.000438 |
| S | 1073 | K1073N | aaG | aaC | 1 | 1 | B.1.1.318 | 0.000302 |
| S | 1073 | K1073N | aaG | aaC | 1 | 1 | B.1.1.466 | 0.008696 |
| S | 1073 | K1073N | aaG | aaC | 1 | 1 | B.1.177.81 | 0.000189 |
| S | 1073 | K1073N | aaG | aaC | 1 | 1 | B.1.422 | 0.000812 |
| S | 1073 | K1073N | aaG | aaC | 1 | 1 | B.1.595 | 0.000261 |
| S | 1073 | K1073N | aaG | aaC | 1 | 1 | B.6.6 | 0.000889 |
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CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk
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