CoV-GLUE Mutation

CoV-GLUE Mutation: ORF = S : CodonNum = 1045 & Codon = aGg

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORF	CodonNum	Mut	ORF1abMut	MutType	RefCodon	MutCodon	AACount	CodonCount	CodonProp	Genome Position
S	1045	K1045R		nonsyn	aAg	aGg	338	334	0.988166	24695-24697

Details of the mutation no within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORF	CodonNum	Mut	RefCodon	MutCodon	CodonCount	AACount	Lineage	LineageCodonProp
S	1045	K1045R	aAg	aGg	334	338	All	0.000064
S	1045	K1045R	aAg	aGg	50	50	AY.98	0.00395
S	1045	K1045R	aAg	aGg	50	50	P.1.7	0.015964
S	1045	K1045R	aAg	aGg	30	30	B.1.1.7	0.000027
S	1045	K1045R	aAg	aGg	19	19	B.1.177	0.00025
S	1045	K1045R	aAg	aGg	17	17	R.1	0.00153
S	1045	K1045R	aAg	aGg	15	16	B.1	0.000137
S	1045	K1045R	aAg	aGg	12	12	AY.4	0.000019
S	1045	K1045R	aAg	aGg	9	9	AY.44	0.000055
S	1045	K1045R	aAg	aGg	9	9	B.1.1	0.000163
S	1045	K1045R	aAg	aGg	9	9	B.1.160	0.000281
S	1045	K1045R	aAg	aGg	8	8	AY.14	0.000704
S	1045	K1045R	aAg	aGg	7	7	AY.33	0.000467
S	1045	K1045R	aAg	aGg	7	7	AY.5.3	0.002362
S	1045	K1045R	aAg	aGg	6	6	AY.1	0.002374
S	1045	K1045R	aAg	aGg	5	5	B.1.1.70	0.001705
S	1045	K1045R	aAg	aGg	4	4	AY.43	0.000018
S	1045	K1045R	aAg	aGg	4	4	B.1.221	0.000284
S	1045	K1045R	aAg	aGg	4	4	B.1.258	0.000266
S	1045	K1045R	aAg	aGg	3	3	AY.103	0.000019
S	1045	K1045R	aAg	aGg	3	3	AY.20	0.000117
S	1045	K1045R	aAg	aGg	3	3	AY.25	0.000018
S	1045	K1045R	aAg	aGg	3	3	AY.26	0.000085
S	1045	K1045R	aAg	aGg	2	3	AY.39	0.000049
S	1045	K1045R	aAg	aGg	3	3	AY.47	0.000093
S	1045	K1045R	aAg	aGg	3	3	B.1.36.36	0.001806
S	1045	K1045R	aAg	aGg	2	3	B.1.617.2	0.000008
S	1045	K1045R	aAg	aGg	2	2	AY.100	0.000092
S	1045	K1045R	aAg	aGg	2	2	AY.3	0.00002
S	1045	K1045R	aAg	aGg	2	2	B.1.1.161	0.007067
S	1045	K1045R	aAg	aGg	2	2	B.1.1.39	0.001019
S	1045	K1045R	aAg	aGg	2	2	B.1.160.9	0.014388
S	1045	K1045R	aAg	aGg	2	2	B.1.177.21	0.000153
S	1045	K1045R	aAg	aGg	2	2	B.1.2	0.000018
S	1045	K1045R	aAg	aGg	2	2	C.36.3	0.001134
S	1045	K1045R	aAg	aGg	2	2	P.1	0.000032
S	1045	K1045R	aAg	aGg	1	1	AY.107	0.000466
S	1045	K1045R	aAg	aGg	1	1	AY.113	0.000142
S	1045	K1045R	aAg	aGg	1	1	AY.116	0.000287
S	1045	K1045R	aAg	aGg	1	1	AY.13	0.000161
S	1045	K1045R	aAg	aGg	1	1	AY.41	0.000294
S	1045	K1045R	aAg	aGg	1	1	AY.67	0.000464
S	1045	K1045R	aAg	aGg	1	1	AY.75	0.000056
S	1045	K1045R	aAg	aGg	1	1	AY.75.1	0.00018
S	1045	K1045R	aAg	aGg	1	1	B	0.000128
S	1045	K1045R	aAg	aGg	1	1	B.1.1.241	0.00207
S	1045	K1045R	aAg	aGg	1	1	B.1.1.409	0.002833
S	1045	K1045R	aAg	aGg	1	1	B.1.1.433	0.001425
S	1045	K1045R	aAg	aGg	1	1	B.1.1.8	0.003584
S	1045	K1045R	aAg	aGg	1	1	B.1.160.14	0.002119
S	1045	K1045R	aAg	aGg	1	1	B.1.160.16	0.000929
S	1045	K1045R	aAg	aGg	1	1	B.1.160.32	0.004292
S	1045	K1045R	aAg	aGg	1	1	B.1.177.12	0.000152
S	1045	K1045R	aAg	aGg	1	1	B.1.177.23	0.003236
S	1045	K1045R	aAg	aGg	1	1	B.1.177.43	0.001477
S	1045	K1045R	aAg	aGg	1	1	B.1.177.44	0.000519
S	1045	K1045R	aAg	aGg	1	1	B.1.177.89	0.02439
S	1045	K1045R	aAg	aGg	1	1	B.1.222	0.001692
S	1045	K1045R	aAg	aGg	1	1	B.1.258.17	0.000104
S	1045	K1045R	aAg	aGg	1	1	B.1.588	0.00091
S	1045	K1045R	aAg	aGg	1	1	B.1.590	0.004545
S	1045	K1045R	aAg	aGg	1	1	B.1.595	0.000261
S	1045	K1045R	aAg	aGg	1	1	B.1.620	0.000946
S	1045	K1045R	aAg	aGg	1	1	B.1.621	0.000089
S	1045	K1045R	aAg	aGg	1	1	B.1.637	0.000073

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.