CoV-GLUE Mutation

CoV-GLUE Mutation: ORF = ORF8 : Mut = Y46del

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORF	CodonNum	Mut	ORF1abMut	MutType	RefCodon	MutCodon	AACount	CodonCount	CodonProp	Genome Position
ORF8	46	Y46del		del	TAT	---	2034	2034	1	28029-28031

Details of the mutation Y46del within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORF	CodonNum	Mut	RefCodon	MutCodon	CodonCount	AACount	Lineage	LineageCodonProp
ORF8	46	Y46del	TAT	---	2034	2034	All	0.000389
ORF8	46	Y46del	TAT	---	991	991	B.1.1.7	0.000887
ORF8	46	Y46del	TAT	---	105	105	AY.4	0.000163
ORF8	46	Y46del	TAT	---	82	82	B.1.617.2	0.000309
ORF8	46	Y46del	TAT	---	67	67	AY.103	0.000416
ORF8	46	Y46del	TAT	---	58	58	B.1.1.294	0.073418
ORF8	46	Y46del	TAT	---	45	45	B.1.351	0.001338
ORF8	46	Y46del	TAT	---	43	43	AY.3	0.000428
ORF8	46	Y46del	TAT	---	41	41	AY.29	0.000647
ORF8	46	Y46del	TAT	---	37	37	B.1.1	0.000671
ORF8	46	Y46del	TAT	---	35	35	AY.44	0.000213
ORF8	46	Y46del	TAT	---	34	34	AY.43	0.000151
ORF8	46	Y46del	TAT	---	34	34	B.1.243	0.002366
ORF8	46	Y46del	TAT	---	33	33	B.1.1.222	0.006732
ORF8	46	Y46del	TAT	---	33	33	B.1.160	0.001029
ORF8	46	Y46del	TAT	---	31	31	AY.102	0.000822
ORF8	46	Y46del	TAT	---	19	19	B	0.002428
ORF8	46	Y46del	TAT	---	14	14	B.1.160.16	0.013011
ORF8	46	Y46del	TAT	---	13	13	B.1.1.318	0.003923
ORF8	46	Y46del	TAT	---	13	13	P.1	0.000205
ORF8	46	Y46del	TAT	---	12	12	AY.27	0.000777
ORF8	46	Y46del	TAT	---	12	12	B.1	0.00011
ORF8	46	Y46del	TAT	---	11	11	B.1.2	0.000097
ORF8	46	Y46del	TAT	---	9	9	AY.118	0.000564
ORF8	46	Y46del	TAT	---	9	9	AY.25	0.000054
ORF8	46	Y46del	TAT	---	9	9	AY.26	0.000255
ORF8	46	Y46del	TAT	---	8	8	B.1.1.284	0.000859
ORF8	46	Y46del	TAT	---	8	8	B.1.240	0.001725
ORF8	46	Y46del	TAT	---	8	8	B.1.628	0.002819
ORF8	46	Y46del	TAT	---	7	7	AY.4.2	0.000152
ORF8	46	Y46del	TAT	---	7	7	B.1.1.265	0.022082
ORF8	46	Y46del	TAT	---	7	7	B.1.1.519	0.000278
ORF8	46	Y46del	TAT	---	7	7	B.1.36.16	0.009972
ORF8	46	Y46del	TAT	---	7	7	P.1.14	0.000335
ORF8	46	Y46del	TAT	---	6	6	AY.119	0.000212
ORF8	46	Y46del	TAT	---	6	6	AY.32	0.003195
ORF8	46	Y46del	TAT	---	6	6	AY.35	0.001398
ORF8	46	Y46del	TAT	---	6	6	B.1.177.83	0.008889
ORF8	46	Y46del	TAT	---	6	6	B.1.243.2	0.086957
ORF8	46	Y46del	TAT	---	5	5	AY.29.1	0.001103
ORF8	46	Y46del	TAT	---	5	5	AY.39	0.000124
ORF8	46	Y46del	TAT	---	5	5	AY.47	0.000156
ORF8	46	Y46del	TAT	---	5	5	B.1.1.389	0.030303
ORF8	46	Y46del	TAT	---	5	5	B.1.177	0.000066
ORF8	46	Y46del	TAT	---	4	4	AY.34	0.000388
ORF8	46	Y46del	TAT	---	4	4	AY.6	0.000165
ORF8	46	Y46del	TAT	---	4	4	AY.7.2	0.002237
ORF8	46	Y46del	TAT	---	4	4	B.1.1.214	0.000222
ORF8	46	Y46del	TAT	---	4	4	B.1.429	0.000094
ORF8	46	Y46del	TAT	---	4	4	B.1.526	0.000094
ORF8	46	Y46del	TAT	---	3	3	AY.5	0.000062
ORF8	46	Y46del	TAT	---	3	3	B.1.1.398	0.009677
ORF8	46	Y46del	TAT	---	3	3	B.1.22	0.003953
ORF8	46	Y46del	TAT	---	3	3	B.1.509	0.002597
ORF8	46	Y46del	TAT	---	3	3	P.1.1	0.000953
ORF8	46	Y46del	TAT	---	3	3	P.1.15	0.000697
ORF8	46	Y46del	TAT	---	2	2		0.111111
ORF8	46	Y46del	TAT	---	2	2	AY.100	0.000092
ORF8	46	Y46del	TAT	---	2	2	AY.108	0.002205
ORF8	46	Y46del	TAT	---	2	2	AY.46	0.000208
ORF8	46	Y46del	TAT	---	2	2	AY.48	0.00093
ORF8	46	Y46del	TAT	---	2	2	AY.84	0.000875
ORF8	46	Y46del	TAT	---	2	2	AY.98.1	0.000097
ORF8	46	Y46del	TAT	---	2	2	B.1.126	0.002551
ORF8	46	Y46del	TAT	---	2	2	B.1.177.77	0.001452
ORF8	46	Y46del	TAT	---	2	2	B.1.206	0.001631
ORF8	46	Y46del	TAT	---	2	2	B.1.210	0.004264
ORF8	46	Y46del	TAT	---	2	2	B.1.258.17	0.000208
ORF8	46	Y46del	TAT	---	2	2	B.1.36	0.000292
ORF8	46	Y46del	TAT	---	2	2	B.1.427	0.000101
ORF8	46	Y46del	TAT	---	2	2	B.40	0.000729
ORF8	46	Y46del	TAT	---	2	2	P.1.17	0.000324
ORF8	46	Y46del	TAT	---	2	2	Q.8	0.00033
ORF8	46	Y46del	TAT	---	1	1	A.23	0.010526
ORF8	46	Y46del	TAT	---	1	1	AE.4	0.043478
ORF8	46	Y46del	TAT	---	1	1	AY.13	0.000161
ORF8	46	Y46del	TAT	---	1	1	AY.14	0.000088
ORF8	46	Y46del	TAT	---	1	1	AY.20	0.000039
ORF8	46	Y46del	TAT	---	1	1	AY.23	0.00007
ORF8	46	Y46del	TAT	---	1	1	AY.4.4	0.000409
ORF8	46	Y46del	TAT	---	1	1	AY.42	0.00004
ORF8	46	Y46del	TAT	---	1	1	AY.45	0.000122
ORF8	46	Y46del	TAT	---	1	1	AY.5.3	0.000337
ORF8	46	Y46del	TAT	---	1	1	AY.70	0.000209
ORF8	46	Y46del	TAT	---	1	1	AY.74	0.000116
ORF8	46	Y46del	TAT	---	1	1	AY.9	0.000068
ORF8	46	Y46del	TAT	---	1	1	AY.92	0.000287
ORF8	46	Y46del	TAT	---	1	1	AY.98	0.000079
ORF8	46	Y46del	TAT	---	1	1	AY.99.2	0.000092
ORF8	46	Y46del	TAT	---	1	1	AZ.2	0.000821
ORF8	46	Y46del	TAT	---	1	1	B.1.1.174	0.003378
ORF8	46	Y46del	TAT	---	1	1	B.1.1.207	0.001182
ORF8	46	Y46del	TAT	---	1	1	B.1.1.216	0.00089
ORF8	46	Y46del	TAT	---	1	1	B.1.1.25	0.000569
ORF8	46	Y46del	TAT	---	1	1	B.1.1.269	0.001353
ORF8	46	Y46del	TAT	---	1	1	B.1.1.297	0.002237
ORF8	46	Y46del	TAT	---	1	1	B.1.1.322	0.008772
ORF8	46	Y46del	TAT	---	1	1	B.1.1.354	0.004386
ORF8	46	Y46del	TAT	---	1	1	B.1.1.37	0.000193
ORF8	46	Y46del	TAT	---	1	1	B.1.1.517	0.006803
ORF8	46	Y46del	TAT	---	1	1	B.1.1.521	0.005348
ORF8	46	Y46del	TAT	---	1	1	B.1.1.63	0.000386
ORF8	46	Y46del	TAT	---	1	1	B.1.177.12	0.000152
ORF8	46	Y46del	TAT	---	1	1	B.1.177.21	0.000076
ORF8	46	Y46del	TAT	---	1	1	B.1.177.7	0.000165
ORF8	46	Y46del	TAT	---	1	1	B.1.195	0.005025
ORF8	46	Y46del	TAT	---	1	1	B.1.258	0.000067
ORF8	46	Y46del	TAT	---	1	1	B.1.258.12	0.007874
ORF8	46	Y46del	TAT	---	1	1	B.1.258.9	0.005
ORF8	46	Y46del	TAT	---	1	1	B.1.351.2	0.000303
ORF8	46	Y46del	TAT	---	1	1	B.1.445	0.011765
ORF8	46	Y46del	TAT	---	1	1	B.1.468	0.005714
ORF8	46	Y46del	TAT	---	1	1	B.1.525	0.000113
ORF8	46	Y46del	TAT	---	1	1	B.1.540	0.009709
ORF8	46	Y46del	TAT	---	1	1	B.1.549	0.007194
ORF8	46	Y46del	TAT	---	1	1	B.1.564	0.000426
ORF8	46	Y46del	TAT	---	1	1	B.1.576	0.000907
ORF8	46	Y46del	TAT	---	1	1	B.1.596	0.000087
ORF8	46	Y46del	TAT	---	1	1	B.1.621	0.000089
ORF8	46	Y46del	TAT	---	1	1	B.34	0.013699
ORF8	46	Y46del	TAT	---	1	1	C.26	0.007353
ORF8	46	Y46del	TAT	---	1	1	C.37	0.000116
ORF8	46	Y46del	TAT	---	1	1	M.3	0.076923
ORF8	46	Y46del	TAT	---	1	1	N.6	0.007092
ORF8	46	Y46del	TAT	---	1	1	P.1.12	0.000484
ORF8	46	Y46del	TAT	---	1	1	P.1.7	0.000319
ORF8	46	Y46del	TAT	---	1	1	R.1	0.00009

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.