CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF8 : Mut = P93L

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF893P93LnonsyncCtcTt159615090.94548928170-28172
ORF893P93LnonsynCCTTTA1596640.040100328170-28172
ORF893P93LnonsyncCTcTA1596160.010025128170-28172
ORF893P93LnonsynCCTTTG159650.0031328328170-28172
ORF893P93LnonsyncCTcTC159610.00062656628170-28172
ORF893P93LnonsyncCTcTG159610.00062656628170-28172

Details of the mutation P93L within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF893P93LcCtcTt15091596All0.000289
ORF893P93LCCTTTA641596All0.000012
ORF893P93LcCTcTA161596All0.000003
ORF893P93LCCTTTG51596All0.000001
ORF893P93LcCTcTC11596All0
ORF893P93LcCTcTG11596All0
ORF893P93LcCtcTt502581B.1.1.70.000449
ORF893P93LCCTTTA59581B.1.1.70.000053
ORF893P93LcCTcTA13581B.1.1.70.000012
ORF893P93LCCTTTG5581B.1.1.70.000004
ORF893P93LcCTcTG1581B.1.1.70.000001
ORF893P93LcCTcTC1581B.1.1.70.000001
ORF893P93LcCtcTt207207B.1.20.001823
ORF893P93LcCtcTt110110AY.1030.000683
ORF893P93LcCtcTt8384B.1.617.20.000313
ORF893P93LcCTcTA184B.1.617.20.000004
ORF893P93LcCtcTt5757AY.40.000089
ORF893P93LcCtcTt4950B.1.10.000889
ORF893P93LCCTTTA150B.1.10.000018
ORF893P93LcCtcTt4747AY.440.000286
ORF893P93LcCtcTt4747B.1.1.3370.169065
ORF893P93LcCtcTt4343B.1.220.056653
ORF893P93LcCtcTt3333B.1.177.430.048744
ORF893P93LcCtcTt2931B.10.000266
ORF893P93LCCTTTA231B.10.000018
ORF893P93LcCtcTt2626P.10.00041
ORF893P93LcCtcTt2323AY.390.000568
ORF893P93LcCtcTt2323AY.430.000102
ORF893P93LcCtcTt1818AY.30.000179
ORF893P93LcCtcTt1717AY.98.10.000823
ORF893P93LcCtcTt1616B.1.1600.000499
ORF893P93LcCtcTt1414AY.420.000563
ORF893P93LcCtcTt79AY.250.000042
ORF893P93LCCTTTA19AY.250.000006
ORF893P93LcCTcTA19AY.250.000006
ORF893P93LcCtcTt77C.1.10.538462
ORF893P93LcCtcTt77P.1.140.000335
ORF893P93LcCtcTt66AY.1020.000159
ORF893P93LcCtcTt55AY.260.000142
ORF893P93LcCtcTt55AY.3.10.000426
ORF893P93LcCtcTt55B.1.1.2740.025253
ORF893P93LcCtcTt55B.1.6090.002397
ORF893P93LcCtcTt44AY.1190.000141
ORF893P93LcCtcTt44B.1.1770.000053
ORF893P93LcCtcTt44B.1.4110.014815
ORF893P93LcCtcTt44B.1.5960.000349
ORF893P93LcCtcTt44P.1.170.000647
ORF893P93LcCtcTt33AY.200.000117
ORF893P93LcCtcTt33AY.230.000209
ORF893P93LcCtcTt33AY.340.000291
ORF893P93LcCtcTt33AY.4.20.000065
ORF893P93LcCtcTt33AY.470.000093
ORF893P93LcCtcTt33B.1.1.2940.003797
ORF893P93LcCtcTt33B.1.2360.00616
ORF893P93LcCtcTt22AY.1050.001286
ORF893P93LcCtcTt22AY.1170.000169
ORF893P93LcCtcTt22AY.4.2.10.000298
ORF893P93LcCtcTt22AY.550.001835
ORF893P93LcCtcTt22AY.60.000082
ORF893P93LcCtcTt22AY.820.002714
ORF893P93LcCtcTt22AY.840.000875
ORF893P93LcCtcTt22B.1.1.2690.002706
ORF893P93LcCtcTt22B.1.1.3750.02381
ORF893P93LcCtcTt22B.1.1.5190.000079
ORF893P93LcCtcTt22B.1.2580.000133
ORF893P93LcCtcTt22B.1.360.000292
ORF893P93LcCtcTt22B.1.4270.000101
ORF893P93LcCtcTt22B.1.4560.006536
ORF893P93LcCtcTt22B.1.5250.000226
ORF893P93LcCtcTt22C.370.000232
ORF893P93LcCtcTt12P.1.150.000232
ORF893P93LcCTcTA12P.1.150.000232
ORF893P93LcCtcTt22P.1.70.000639
ORF893P93LcCtcTt11AY.1000.000046
ORF893P93LcCtcTt11AY.1010.00049
ORF893P93LcCtcTt11AY.1090.00074
ORF893P93LcCtcTt11AY.1100.000113
ORF893P93LcCtcTt11AY.1180.000063
ORF893P93LcCtcTt11AY.120.10.000321
ORF893P93LcCtcTt11AY.130.000161
ORF893P93LcCtcTt11AY.320.000532
ORF893P93LcCtcTt11AY.34.10.00051
ORF893P93LcCtcTt11AY.4.40.000409
ORF893P93LcCtcTt11AY.50.000021
ORF893P93LcCtcTt11AY.540.000095
ORF893P93LcCtcTt11AY.740.000116
ORF893P93LcCtcTt11AY.920.000287
ORF893P93LcCtcTt11B0.000128
ORF893P93LcCtcTt11B.1.1.10.000327
ORF893P93LcCtcTt11B.1.1.1700.001247
ORF893P93LcCtcTt11B.1.1.2140.000055
ORF893P93LcCtcTt11B.1.1.2220.000204
ORF893P93LcCtcTt11B.1.1.250.000569
ORF893P93LcCtcTt11B.1.1.3560.008547
ORF893P93LcCtcTt11B.1.1.40.002976
ORF893P93LcCtcTt11B.1.2210.000071
ORF893P93LcCtcTt11B.1.2410.000812
ORF893P93LcCtcTt11B.1.258.170.000104
ORF893P93LcCtcTt11B.1.3050.002151
ORF893P93LcCtcTt11B.1.3510.00003
ORF893P93LcCtcTt11B.1.36.290.000517
ORF893P93LcCtcTt11B.1.3690.000285
ORF893P93LcCtcTt11B.1.4290.000024
ORF893P93LcCtcTt11B.1.4990.00105
ORF893P93LcCtcTt11B.1.5260.000024
ORF893P93LCCTTTA11B.1.5740.002151
ORF893P93LcCtcTt11B.1.617.10.000129
ORF893P93LcCtcTt11B.1.6210.000089
ORF893P93LcCtcTt11B.1.6280.000352
ORF893P93LcCtcTt11B.1.6320.006711
ORF893P93LcCtcTt11C.140.004329
ORF893P93LcCtcTt11P.1.10.000318
ORF893P93LcCtcTt11P.1.120.000484
ORF893P93LcCtcTt11P.1.160.000374
ORF893P93LcCtcTt11P.20.000187
ORF893P93LcCtcTt11Q.80.000165

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

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