CoV-GLUE Mutation

CoV-GLUE Mutation: ORF = ORF8 : Mut = P38S

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORF	CodonNum	Mut	ORF1abMut	MutType	RefCodon	MutCodon	AACount	CodonCount	CodonProp	Genome Position
ORF8	38	P38S		nonsyn	Cct	Tct	17601	17578	0.998693	28005-28007
ORF8	38	P38S		nonsyn	CcT	TcC	17601	23	0.00130674	28005-28007

Details of the mutation P38S within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORF	CodonNum	Mut	RefCodon	MutCodon	CodonCount	AACount	Lineage	LineageCodonProp
ORF8	38	P38S	Cct	Tct	17578	17601	All	0.003362
ORF8	38	P38S	CcT	TcC	23	17601	All	0.000004
ORF8	38	P38S	Cct	Tct	11091	11092	B.1.621	0.981765
ORF8	38	P38S	CcT	TcC	1	11092	B.1.621	0.000089
ORF8	38	P38S	Cct	Tct	1953	1953	B.1.621.1	0.98786
ORF8	38	P38S	Cct	Tct	1053	1053	B.1.1.7	0.000943
ORF8	38	P38S	Cct	Tct	511	511	B.1.637	0.03734
ORF8	38	P38S	Cct	Tct	312	312	B.1.177	0.004108
ORF8	38	P38S	Cct	Tct	302	302	AY.4	0.00047
ORF8	38	P38S	Cct	Tct	208	208	AY.43	0.000922
ORF8	38	P38S	Cct	Tct	176	176	B.1	0.001612
ORF8	38	P38S	Cct	Tct	166	166	B.1.351	0.004935
ORF8	38	P38S	Cct	Tct	147	161	B.1.617.2	0.000554
ORF8	38	P38S	CcT	TcC	14	161	B.1.617.2	0.000053
ORF8	38	P38S	Cct	Tct	129	129	AY.7.1	0.014538
ORF8	38	P38S	Cct	Tct	95	95	AD.2	0.020801
ORF8	38	P38S	Cct	Tct	75	75	AY.103	0.000466
ORF8	38	P38S	Cct	Tct	75	75	B.1.526	0.001763
ORF8	38	P38S	Cct	Tct	69	69	AY.4.2	0.001497
ORF8	38	P38S	Cct	Tct	56	56	AY.3	0.000557
ORF8	38	P38S	Cct	Tct	52	52	AY.25	0.000313
ORF8	38	P38S	Cct	Tct	51	51	B.1.2	0.000449
ORF8	38	P38S	Cct	Tct	51	51	Q.2	0.031288
ORF8	38	P38S	Cct	Tct	48	48	AY.33	0.003205
ORF8	38	P38S	Cct	Tct	45	45	B.1.429	0.001059
ORF8	38	P38S	Cct	Tct	42	42	B.1.1.99	1
ORF8	38	P38S	Cct	Tct	33	33	AY.46.6	0.002383
ORF8	38	P38S	Cct	Tct	31	31	B.1.366	0.15122
ORF8	38	P38S	Cct	Tct	29	29	AY.102	0.000769
ORF8	38	P38S	Cct	Tct	29	29	AY.20	0.001127
ORF8	38	P38S	Cct	Tct	29	29	AY.45	0.003529
ORF8	38	P38S	Cct	Tct	28	28	B.1.1	0.000508
ORF8	38	P38S	Cct	Tct	28	28	B.1.221	0.001989
ORF8	38	P38S	Cct	Tct	27	27	B.1.160	0.000842
ORF8	38	P38S	Cct	Tct	24	24	AY.46	0.002498
ORF8	38	P38S	Cct	Tct	23	23	B.1.623	0.012339
ORF8	38	P38S	Cct	Tct	20	20	B.1.1.1	0.006534
ORF8	38	P38S	Cct	Tct	18	18	B.1.258.17	0.001871
ORF8	38	P38S	Cct	Tct	18	18	C.37	0.002089
ORF8	38	P38S	Cct	Tct	16	16	P.1	0.000252
ORF8	38	P38S	Cct	Tct	15	15	AY.3.1	0.001279
ORF8	38	P38S	Cct	Tct	15	15	B.1.427	0.000757
ORF8	38	P38S	Cct	Tct	14	14	AY.44	0.000085
ORF8	38	P38S	Cct	Tct	13	13	AY.29	0.000205
ORF8	38	P38S	Cct	Tct	13	13	AY.5	0.000268
ORF8	38	P38S	Cct	Tct	13	13	C.39	0.245283
ORF8	38	P38S	Cct	Tct	12	12	AY.119	0.000424
ORF8	38	P38S	Cct	Tct	11	11	B	0.001406
ORF8	38	P38S	Cct	Tct	10	10	AY.26	0.000283
ORF8	38	P38S	Cct	Tct	10	10	AY.9.2	0.000367
ORF8	38	P38S	Cct	Tct	10	10	AZ.3	0.015198
ORF8	38	P38S	Cct	Tct	9	9	AY.39.1	0.000357
ORF8	38	P38S	Cct	Tct	9	9	B.1.1.274	0.045455
ORF8	38	P38S	Cct	Tct	9	9	P.1.14	0.00043
ORF8	38	P38S	Cct	Tct	7	7	AY.39	0.000173
ORF8	38	P38S	Cct	Tct	7	7	AZ.1	0.006071
ORF8	38	P38S	Cct	Tct	7	7	B.1.1.33	0.002946
ORF8	38	P38S	Cct	Tct	7	7	B.1.1.519	0.000278
ORF8	38	P38S	Cct	Tct	7	7	B.1.177.12	0.001062
ORF8	38	P38S	Cct	Tct	7	7	P.1.15	0.001626
ORF8	38	P38S	Cct	Tct	6	6	AY.9.1	0.000502
ORF8	38	P38S	Cct	Tct	6	6	AY.98.1	0.000291
ORF8	38	P38S	Cct	Tct	6	6	B.1.177.86	0.001101
ORF8	38	P38S	Cct	Tct	6	6	B.40	0.002186
ORF8	38	P38S	Cct	Tct	6	6	Q.8	0.000989
ORF8	38	P38S	CcT	TcC	5	5	AY.100	0.00023
ORF8	38	P38S	Cct	Tct	4	5	AY.117	0.000338
ORF8	38	P38S	CcT	TcC	1	5	AY.117	0.000085
ORF8	38	P38S	Cct	Tct	5	5	AY.36	0.000741
ORF8	38	P38S	Cct	Tct	5	5	AY.41	0.00147
ORF8	38	P38S	Cct	Tct	5	5	B.1.221.3	0.004167
ORF8	38	P38S	Cct	Tct	4	4	AY.120	0.000149
ORF8	38	P38S	Cct	Tct	4	4	AY.23	0.000279
ORF8	38	P38S	Cct	Tct	4	4	AY.23.1	0.001669
ORF8	38	P38S	Cct	Tct	4	4	AY.34	0.000388
ORF8	38	P38S	Cct	Tct	4	4	AY.6	0.000165
ORF8	38	P38S	Cct	Tct	4	4	AY.75	0.000224
ORF8	38	P38S	Cct	Tct	4	4	AY.9	0.00027
ORF8	38	P38S	Cct	Tct	4	4	B.1.1.284	0.00043
ORF8	38	P38S	Cct	Tct	4	4	B.1.177.73	0.002265
ORF8	38	P38S	Cct	Tct	4	4	B.1.351.5	0.002398
ORF8	38	P38S	Cct	Tct	4	4	B.1.409	0.003125
ORF8	38	P38S	Cct	Tct	4	4	B.1.517	0.001708
ORF8	38	P38S	Cct	Tct	4	4	D.2	0.0003
ORF8	38	P38S	Cct	Tct	3	3	A	0.001161
ORF8	38	P38S	Cct	Tct	3	3	AY.110	0.000338
ORF8	38	P38S	Cct	Tct	3	3	AY.118	0.000188
ORF8	38	P38S	Cct	Tct	3	3	AY.29.1	0.000662
ORF8	38	P38S	Cct	Tct	3	3	AY.30	0.001187
ORF8	38	P38S	Cct	Tct	3	3	AY.7	0.000588
ORF8	38	P38S	Cct	Tct	3	3	AY.98	0.000237
ORF8	38	P38S	Cct	Tct	3	3	B.1.1.28	0.000934
ORF8	38	P38S	Cct	Tct	3	3	B.1.1.315	0.025424
ORF8	38	P38S	Cct	Tct	3	3	B.1.1.52	0.036585
ORF8	38	P38S	Cct	Tct	3	3	B.1.157	0.008955
ORF8	38	P38S	Cct	Tct	3	3	B.1.177.81	0.000568
ORF8	38	P38S	Cct	Tct	3	3	B.1.258	0.0002
ORF8	38	P38S	Cct	Tct	3	3	B.1.258.14	0.002941
ORF8	38	P38S	Cct	Tct	3	3	B.1.36.18	0.001261
ORF8	38	P38S	Cct	Tct	3	3	B.1.36.38	0.004926
ORF8	38	P38S	Cct	Tct	3	3	B.1.438.1	0.000322
ORF8	38	P38S	Cct	Tct	3	3	B.1.470	0.004213
ORF8	38	P38S	Cct	Tct	3	3	B.1.525	0.000339
ORF8	38	P38S	Cct	Tct	3	3	B.1.533	0.028846
ORF8	38	P38S	Cct	Tct	3	3	B.1.541	0.013274
ORF8	38	P38S	Cct	Tct	3	3	Q.1	0.000379
ORF8	38	P38S	Cct	Tct	2	2	A.2	0.001324
ORF8	38	P38S	Cct	Tct	2	2	A.2.5	0.000998
ORF8	38	P38S	Cct	Tct	2	2	AY.113	0.000285
ORF8	38	P38S	Cct	Tct	2	2	AY.32	0.001065
ORF8	38	P38S	Cct	Tct	2	2	AY.4.2.1	0.000298
ORF8	38	P38S	Cct	Tct	2	2	AY.4.5	0.000215
ORF8	38	P38S	Cct	Tct	2	2	AY.42	0.00008
ORF8	38	P38S	Cct	Tct	2	2	AY.46.1	0.002053
ORF8	38	P38S	Cct	Tct	2	2	AY.47	0.000062
ORF8	38	P38S	Cct	Tct	2	2	AY.54	0.000191
ORF8	38	P38S	Cct	Tct	2	2	AY.67	0.000929
ORF8	38	P38S	Cct	Tct	2	2	AY.73	0.001331
ORF8	38	P38S	Cct	Tct	2	2	AY.93	0.000546
ORF8	38	P38S	Cct	Tct	2	2	AY.99.1	0.003106
ORF8	38	P38S	Cct	Tct	2	2	AY.99.2	0.000184
ORF8	38	P38S	Cct	Tct	2	2	B.1.1.207	0.002364
ORF8	38	P38S	Cct	Tct	2	2	B.1.1.214	0.000111
ORF8	38	P38S	Cct	Tct	2	2	B.1.1.220	0.003717
ORF8	38	P38S	Cct	Tct	2	2	B.1.1.398	0.006452
ORF8	38	P38S	Cct	Tct	2	2	B.1.131	0.017544
ORF8	38	P38S	Cct	Tct	2	2	B.1.177.60	0.000437
ORF8	38	P38S	Cct	Tct	2	2	B.1.240	0.000431
ORF8	38	P38S	Cct	Tct	2	2	B.1.280	0.014286
ORF8	38	P38S	Cct	Tct	2	2	B.1.282	0.029851
ORF8	38	P38S	Cct	Tct	2	2	B.1.422	0.001625
ORF8	38	P38S	Cct	Tct	2	2	B.1.596	0.000174
ORF8	38	P38S	Cct	Tct	2	2	B.1.8	0.003945
ORF8	38	P38S	Cct	Tct	2	2	P.1.12	0.000968
ORF8	38	P38S	Cct	Tct	2	2	P.1.7	0.000639
ORF8	38	P38S	Cct	Tct	1	1	A.2.2	0.001689
ORF8	38	P38S	Cct	Tct	1	1	A.5	0.001923
ORF8	38	P38S	Cct	Tct	1	1	AD.1	0.004115
ORF8	38	P38S	Cct	Tct	1	1	AL.1	0.012987
ORF8	38	P38S	Cct	Tct	1	1	AT.1	0.005128
ORF8	38	P38S	Cct	Tct	1	1	AY.105	0.000643
ORF8	38	P38S	Cct	Tct	1	1	AY.116.1	0.000311
ORF8	38	P38S	Cct	Tct	1	1	AY.121	0.000135
ORF8	38	P38S	Cct	Tct	1	1	AY.14	0.000088
ORF8	38	P38S	Cct	Tct	1	1	AY.16	0.00038
ORF8	38	P38S	Cct	Tct	1	1	AY.16.1	0.00047
ORF8	38	P38S	Cct	Tct	1	1	AY.2	0.000356
ORF8	38	P38S	Cct	Tct	1	1	AY.35	0.000233
ORF8	38	P38S	Cct	Tct	1	1	AY.38	0.000499
ORF8	38	P38S	Cct	Tct	1	1	AY.4.3	0.000842
ORF8	38	P38S	Cct	Tct	1	1	AY.46.4	0.000165
ORF8	38	P38S	Cct	Tct	1	1	AY.46.5	0.000198
ORF8	38	P38S	Cct	Tct	1	1	AY.5.1	0.003759
ORF8	38	P38S	Cct	Tct	1	1	AY.5.3	0.000337
ORF8	38	P38S	Cct	Tct	1	1	AY.5.4	0.000277
ORF8	38	P38S	Cct	Tct	1	1	AY.53	0.000288
ORF8	38	P38S	Cct	Tct	1	1	AY.59	0.00053
ORF8	38	P38S	Cct	Tct	1	1	AY.61	0.000105
ORF8	38	P38S	Cct	Tct	1	1	AY.64	0.000595
ORF8	38	P38S	CcT	TcC	1	1	AY.69	0.000187
ORF8	38	P38S	Cct	Tct	1	1	AY.7.2	0.000559
ORF8	38	P38S	Cct	Tct	1	1	AY.71	0.000475
ORF8	38	P38S	Cct	Tct	1	1	AY.75.1	0.00018
ORF8	38	P38S	CcT	TcC	1	1	AY.77	0.001127
ORF8	38	P38S	Cct	Tct	1	1	AY.81	0.001992
ORF8	38	P38S	Cct	Tct	1	1	AY.87	0.000833
ORF8	38	P38S	Cct	Tct	1	1	AY.92	0.000287
ORF8	38	P38S	Cct	Tct	1	1	AY.97	0.001701
ORF8	38	P38S	Cct	Tct	1	1	AY.99	0.001049
ORF8	38	P38S	Cct	Tct	1	1	B.1.1.222	0.000204
ORF8	38	P38S	Cct	Tct	1	1	B.1.1.232	0.001815
ORF8	38	P38S	Cct	Tct	1	1	B.1.1.236	0.006897
ORF8	38	P38S	Cct	Tct	1	1	B.1.1.239	0.032258
ORF8	38	P38S	Cct	Tct	1	1	B.1.1.311	0.000358
ORF8	38	P38S	Cct	Tct	1	1	B.1.1.317	0.000412
ORF8	38	P38S	Cct	Tct	1	1	B.1.1.369	0.000446
ORF8	38	P38S	Cct	Tct	1	1	B.1.1.372	0.000689
ORF8	38	P38S	Cct	Tct	1	1	B.1.1.526	0.003546
ORF8	38	P38S	Cct	Tct	1	1	B.1.1.63	0.000386
ORF8	38	P38S	Cct	Tct	1	1	B.1.1.83	0.00271
ORF8	38	P38S	Cct	Tct	1	1	B.1.108	0.005814
ORF8	38	P38S	Cct	Tct	1	1	B.1.140	0.018868
ORF8	38	P38S	Cct	Tct	1	1	B.1.147	0.000756
ORF8	38	P38S	Cct	Tct	1	1	B.1.167	0.007812
ORF8	38	P38S	Cct	Tct	1	1	B.1.177.16	0.000664
ORF8	38	P38S	Cct	Tct	1	1	B.1.177.33	0.001645
ORF8	38	P38S	Cct	Tct	1	1	B.1.177.51	0.004566
ORF8	38	P38S	Cct	Tct	1	1	B.1.177.54	0.000606
ORF8	38	P38S	Cct	Tct	1	1	B.1.177.7	0.000165
ORF8	38	P38S	Cct	Tct	1	1	B.1.177.82	0.000477
ORF8	38	P38S	Cct	Tct	1	1	B.1.206	0.000816
ORF8	38	P38S	Cct	Tct	1	1	B.1.232	0.000537
ORF8	38	P38S	Cct	Tct	1	1	B.1.234	0.000132
ORF8	38	P38S	Cct	Tct	1	1	B.1.258.11	0.000396
ORF8	38	P38S	Cct	Tct	1	1	B.1.311	0.000275
ORF8	38	P38S	Cct	Tct	1	1	B.1.319	0.003049
ORF8	38	P38S	Cct	Tct	1	1	B.1.324	0.001605
ORF8	38	P38S	Cct	Tct	1	1	B.1.336	0.002439
ORF8	38	P38S	Cct	Tct	1	1	B.1.367	0.000792
ORF8	38	P38S	Cct	Tct	1	1	B.1.369	0.000285
ORF8	38	P38S	Cct	Tct	1	1	B.1.391	0.001127
ORF8	38	P38S	Cct	Tct	1	1	B.1.396	0.000706
ORF8	38	P38S	Cct	Tct	1	1	B.1.399	0.001934
ORF8	38	P38S	Cct	Tct	1	1	B.1.459	0.004082
ORF8	38	P38S	Cct	Tct	1	1	B.1.466.2	0.000391
ORF8	38	P38S	Cct	Tct	1	1	B.1.469	0.00361
ORF8	38	P38S	Cct	Tct	1	1	B.1.499	0.00105
ORF8	38	P38S	Cct	Tct	1	1	B.1.575	0.000303
ORF8	38	P38S	Cct	Tct	1	1	B.1.589	0.007576
ORF8	38	P38S	Cct	Tct	1	1	B.1.595	0.000261
ORF8	38	P38S	Cct	Tct	1	1	B.1.599	0.00365
ORF8	38	P38S	Cct	Tct	1	1	B.1.606	0.006024
ORF8	38	P38S	Cct	Tct	1	1	B.1.609	0.000479
ORF8	38	P38S	Cct	Tct	1	1	B.1.617.3	0.002985
ORF8	38	P38S	Cct	Tct	1	1	B.1.628	0.000352
ORF8	38	P38S	Cct	Tct	1	1	B.1.630	0.005236
ORF8	38	P38S	Cct	Tct	1	1	B.1.633	0.041667
ORF8	38	P38S	Cct	Tct	1	1	B.1.634	0.003425
ORF8	38	P38S	Cct	Tct	1	1	B.1.638	0.052632
ORF8	38	P38S	Cct	Tct	1	1	C.4	0.01
ORF8	38	P38S	Cct	Tct	1	1	P.1.16	0.000374
ORF8	38	P38S	Cct	Tct	1	1	P.1.17	0.000162
ORF8	38	P38S	Cct	Tct	1	1	P.2	0.000187
ORF8	38	P38S	Cct	Tct	1	1	Q.3	0.000145
ORF8	38	P38S	Cct	Tct	1	1	Q.7	0.001111

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.