CoV-GLUE | Mutations | Mutation
Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):
ORF | CodonNum | Mut | ORF1abMut | MutType | RefCodon | MutCodon | AACount | CodonCount | CodonProp | Genome Position |
ORF8 | 30 | P30L | nonsyn | cCa | cTa | 4544 | 4539 | 0.9989 | 27981-27983 | |
ORF8 | 30 | P30L | nonsyn | CCa | TTa | 4544 | 5 | 0.00110035 | 27981-27983 |
Details of the mutation P30L within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):
ORF | CodonNum | Mut | RefCodon | MutCodon | CodonCount | AACount | Lineage | LineageCodonProp |
ORF8 | 30 | P30L | cCa | cTa | 4539 | 4544 | All | 0.000868 |
ORF8 | 30 | P30L | CCa | TTa | 5 | 4544 | All | 0.000001 |
ORF8 | 30 | P30L | cCa | cTa | 2966 | 2967 | B.1.177 | 0.039055 |
ORF8 | 30 | P30L | CCa | TTa | 1 | 2967 | B.1.177 | 0.000013 |
ORF8 | 30 | P30L | cCa | cTa | 265 | 265 | B.1.1.7 | 0.000237 |
ORF8 | 30 | P30L | cCa | cTa | 247 | 247 | AY.43 | 0.001094 |
ORF8 | 30 | P30L | cCa | cTa | 148 | 148 | B.1.617.2 | 0.000557 |
ORF8 | 30 | P30L | cCa | cTa | 145 | 145 | B.1.600 | 0.847953 |
ORF8 | 30 | P30L | cCa | cTa | 95 | 95 | AY.4 | 0.000148 |
ORF8 | 30 | P30L | cCa | cTa | 45 | 45 | B.1 | 0.000412 |
ORF8 | 30 | P30L | cCa | cTa | 40 | 40 | AY.3 | 0.000398 |
ORF8 | 30 | P30L | cCa | cTa | 38 | 38 | AY.103 | 0.000236 |
ORF8 | 30 | P30L | cCa | cTa | 33 | 33 | B.1.160.30 | 0.098214 |
ORF8 | 30 | P30L | cCa | cTa | 31 | 31 | AY.120 | 0.001153 |
ORF8 | 30 | P30L | cCa | cTa | 31 | 31 | B.1.160 | 0.000967 |
ORF8 | 30 | P30L | cCa | cTa | 24 | 24 | C.23 | 0.139535 |
ORF8 | 30 | P30L | cCa | cTa | 24 | 24 | P.1 | 0.000378 |
ORF8 | 30 | P30L | cCa | cTa | 20 | 20 | AY.44 | 0.000122 |
ORF8 | 30 | P30L | cCa | cTa | 20 | 20 | B.1.177.38 | 0.208333 |
ORF8 | 30 | P30L | cCa | cTa | 16 | 16 | B.1.526 | 0.000376 |
ORF8 | 30 | P30L | cCa | cTa | 15 | 15 | AY.25 | 0.00009 |
ORF8 | 30 | P30L | cCa | cTa | 15 | 15 | B.1.311 | 0.004119 |
ORF8 | 30 | P30L | cCa | cTa | 15 | 15 | B.1.429 | 0.000353 |
ORF8 | 30 | P30L | cCa | cTa | 13 | 13 | AY.26 | 0.000368 |
ORF8 | 30 | P30L | cCa | cTa | 13 | 13 | B.1.1 | 0.000236 |
ORF8 | 30 | P30L | cCa | cTa | 13 | 13 | B.1.2 | 0.000114 |
ORF8 | 30 | P30L | cCa | cTa | 11 | 11 | B.1.1.318 | 0.003319 |
ORF8 | 30 | P30L | cCa | cTa | 11 | 11 | B.1.258.17 | 0.001144 |
ORF8 | 30 | P30L | cCa | cTa | 11 | 11 | P.1.14 | 0.000526 |
ORF8 | 30 | P30L | cCa | cTa | 10 | 10 | AY.29 | 0.000158 |
ORF8 | 30 | P30L | cCa | cTa | 9 | 9 | AY.4.2 | 0.000195 |
ORF8 | 30 | P30L | cCa | cTa | 9 | 9 | B.1.1.222 | 0.001836 |
ORF8 | 30 | P30L | cCa | cTa | 8 | 8 | B.1.177.31 | 0.091954 |
ORF8 | 30 | P30L | cCa | cTa | 7 | 7 | B.1.177.53 | 0.016746 |
ORF8 | 30 | P30L | cCa | cTa | 7 | 7 | B.1.177.62 | 0.008343 |
ORF8 | 30 | P30L | CCa | TTa | 4 | 6 | 0.222222 | |
ORF8 | 30 | P30L | cCa | cTa | 2 | 6 | 0.111111 | |
ORF8 | 30 | P30L | cCa | cTa | 6 | 6 | B.1.177.69 | 0.008902 |
ORF8 | 30 | P30L | cCa | cTa | 5 | 5 | AY.23 | 0.000349 |
ORF8 | 30 | P30L | cCa | cTa | 5 | 5 | B.1.1.39 | 0.002548 |
ORF8 | 30 | P30L | cCa | cTa | 5 | 5 | B.1.637 | 0.000365 |
ORF8 | 30 | P30L | cCa | cTa | 4 | 4 | AY.100 | 0.000184 |
ORF8 | 30 | P30L | cCa | cTa | 4 | 4 | AY.9 | 0.00027 |
ORF8 | 30 | P30L | cCa | cTa | 4 | 4 | AY.98.1 | 0.000194 |
ORF8 | 30 | P30L | cCa | cTa | 4 | 4 | AY.99.2 | 0.000369 |
ORF8 | 30 | P30L | cCa | cTa | 4 | 4 | B | 0.000511 |
ORF8 | 30 | P30L | cCa | cTa | 4 | 4 | B.1.221 | 0.000284 |
ORF8 | 30 | P30L | cCa | cTa | 4 | 4 | B.1.351 | 0.000119 |
ORF8 | 30 | P30L | cCa | cTa | 4 | 4 | B.1.369 | 0.001141 |
ORF8 | 30 | P30L | cCa | cTa | 4 | 4 | B.1.416 | 0.005076 |
ORF8 | 30 | P30L | cCa | cTa | 3 | 3 | AY.101 | 0.001471 |
ORF8 | 30 | P30L | cCa | cTa | 3 | 3 | AY.118 | 0.000188 |
ORF8 | 30 | P30L | cCa | cTa | 3 | 3 | AY.39 | 0.000074 |
ORF8 | 30 | P30L | cCa | cTa | 3 | 3 | B.1.1.28 | 0.000934 |
ORF8 | 30 | P30L | cCa | cTa | 3 | 3 | B.1.177.44 | 0.001557 |
ORF8 | 30 | P30L | cCa | cTa | 3 | 3 | B.1.177.73 | 0.001699 |
ORF8 | 30 | P30L | cCa | cTa | 3 | 3 | B.1.243 | 0.000209 |
ORF8 | 30 | P30L | cCa | cTa | 3 | 3 | R.1 | 0.00027 |
ORF8 | 30 | P30L | cCa | cTa | 2 | 2 | AY.116 | 0.000574 |
ORF8 | 30 | P30L | cCa | cTa | 2 | 2 | AY.20 | 0.000078 |
ORF8 | 30 | P30L | cCa | cTa | 2 | 2 | AY.42 | 0.00008 |
ORF8 | 30 | P30L | cCa | cTa | 2 | 2 | AY.46 | 0.000208 |
ORF8 | 30 | P30L | cCa | cTa | 2 | 2 | AY.5 | 0.000041 |
ORF8 | 30 | P30L | cCa | cTa | 2 | 2 | AY.76 | 0.009662 |
ORF8 | 30 | P30L | cCa | cTa | 2 | 2 | B.1.111 | 0.00235 |
ORF8 | 30 | P30L | cCa | cTa | 2 | 2 | B.1.258 | 0.000133 |
ORF8 | 30 | P30L | cCa | cTa | 2 | 2 | B.1.258.14 | 0.001961 |
ORF8 | 30 | P30L | cCa | cTa | 2 | 2 | B.1.351.3 | 0.001753 |
ORF8 | 30 | P30L | cCa | cTa | 2 | 2 | B.1.36 | 0.000292 |
ORF8 | 30 | P30L | cCa | cTa | 2 | 2 | B.1.375 | 0.001639 |
ORF8 | 30 | P30L | cCa | cTa | 2 | 2 | B.1.427 | 0.000101 |
ORF8 | 30 | P30L | cCa | cTa | 2 | 2 | B.1.525 | 0.000226 |
ORF8 | 30 | P30L | cCa | cTa | 2 | 2 | B.6.6 | 0.001778 |
ORF8 | 30 | P30L | cCa | cTa | 2 | 2 | P.1.17 | 0.000324 |
ORF8 | 30 | P30L | cCa | cTa | 1 | 1 | A.2 | 0.000662 |
ORF8 | 30 | P30L | cCa | cTa | 1 | 1 | A.2.4 | 0.003367 |
ORF8 | 30 | P30L | cCa | cTa | 1 | 1 | AY.102 | 0.000027 |
ORF8 | 30 | P30L | cCa | cTa | 1 | 1 | AY.105 | 0.000643 |
ORF8 | 30 | P30L | cCa | cTa | 1 | 1 | AY.113 | 0.000142 |
ORF8 | 30 | P30L | cCa | cTa | 1 | 1 | AY.119 | 0.000035 |
ORF8 | 30 | P30L | cCa | cTa | 1 | 1 | AY.120.1 | 0.000321 |
ORF8 | 30 | P30L | cCa | cTa | 1 | 1 | AY.121 | 0.000135 |
ORF8 | 30 | P30L | cCa | cTa | 1 | 1 | AY.13 | 0.000161 |
ORF8 | 30 | P30L | cCa | cTa | 1 | 1 | AY.14 | 0.000088 |
ORF8 | 30 | P30L | cCa | cTa | 1 | 1 | AY.30 | 0.000396 |
ORF8 | 30 | P30L | cCa | cTa | 1 | 1 | AY.34.1 | 0.00051 |
ORF8 | 30 | P30L | cCa | cTa | 1 | 1 | AY.35 | 0.000233 |
ORF8 | 30 | P30L | cCa | cTa | 1 | 1 | AY.45 | 0.000122 |
ORF8 | 30 | P30L | cCa | cTa | 1 | 1 | AY.46.4 | 0.000165 |
ORF8 | 30 | P30L | cCa | cTa | 1 | 1 | AY.48 | 0.000465 |
ORF8 | 30 | P30L | cCa | cTa | 1 | 1 | AY.5.3 | 0.000337 |
ORF8 | 30 | P30L | cCa | cTa | 1 | 1 | AY.52 | 0.000814 |
ORF8 | 30 | P30L | cCa | cTa | 1 | 1 | AY.6 | 0.000041 |
ORF8 | 30 | P30L | cCa | cTa | 1 | 1 | AY.72 | 0.001361 |
ORF8 | 30 | P30L | cCa | cTa | 1 | 1 | AY.75 | 0.000056 |
ORF8 | 30 | P30L | cCa | cTa | 1 | 1 | AY.75.1 | 0.00018 |
ORF8 | 30 | P30L | cCa | cTa | 1 | 1 | AY.9.2 | 0.000037 |
ORF8 | 30 | P30L | cCa | cTa | 1 | 1 | AY.91 | 0.00073 |
ORF8 | 30 | P30L | cCa | cTa | 1 | 1 | AY.92 | 0.000287 |
ORF8 | 30 | P30L | cCa | cTa | 1 | 1 | AY.98 | 0.000079 |
ORF8 | 30 | P30L | cCa | cTa | 1 | 1 | B.1.1.214 | 0.000055 |
ORF8 | 30 | P30L | cCa | cTa | 1 | 1 | B.1.1.284 | 0.000107 |
ORF8 | 30 | P30L | cCa | cTa | 1 | 1 | B.1.1.306 | 0.000438 |
ORF8 | 30 | P30L | cCa | cTa | 1 | 1 | B.1.1.519 | 0.00004 |
ORF8 | 30 | P30L | cCa | cTa | 1 | 1 | B.1.1.70 | 0.000341 |
ORF8 | 30 | P30L | cCa | cTa | 1 | 1 | B.1.160.14 | 0.002119 |
ORF8 | 30 | P30L | cCa | cTa | 1 | 1 | B.1.160.16 | 0.000929 |
ORF8 | 30 | P30L | cCa | cTa | 1 | 1 | B.1.160.20 | 0.008929 |
ORF8 | 30 | P30L | cCa | cTa | 1 | 1 | B.1.160.9 | 0.007194 |
ORF8 | 30 | P30L | cCa | cTa | 1 | 1 | B.1.177.12 | 0.000152 |
ORF8 | 30 | P30L | cCa | cTa | 1 | 1 | B.1.177.17 | 0.000821 |
ORF8 | 30 | P30L | cCa | cTa | 1 | 1 | B.1.177.35 | 0.000691 |
ORF8 | 30 | P30L | cCa | cTa | 1 | 1 | B.1.177.4 | 0.000211 |
ORF8 | 30 | P30L | cCa | cTa | 1 | 1 | B.1.177.57 | 0.000281 |
ORF8 | 30 | P30L | cCa | cTa | 1 | 1 | B.1.177.75 | 0.001041 |
ORF8 | 30 | P30L | cCa | cTa | 1 | 1 | B.1.177.83 | 0.001481 |
ORF8 | 30 | P30L | cCa | cTa | 1 | 1 | B.1.177.9 | 0.001332 |
ORF8 | 30 | P30L | cCa | cTa | 1 | 1 | B.1.260 | 0.003344 |
ORF8 | 30 | P30L | cCa | cTa | 1 | 1 | B.1.349 | 0.000715 |
ORF8 | 30 | P30L | cCa | cTa | 1 | 1 | B.1.36.7 | 0.004 |
ORF8 | 30 | P30L | cCa | cTa | 1 | 1 | B.1.438.1 | 0.000107 |
ORF8 | 30 | P30L | cCa | cTa | 1 | 1 | B.1.456 | 0.003268 |
ORF8 | 30 | P30L | cCa | cTa | 1 | 1 | B.1.462 | 0.007246 |
ORF8 | 30 | P30L | cCa | cTa | 1 | 1 | B.1.473 | 0.019231 |
ORF8 | 30 | P30L | cCa | cTa | 1 | 1 | B.1.533 | 0.009615 |
ORF8 | 30 | P30L | cCa | cTa | 1 | 1 | B.1.558 | 0.004566 |
ORF8 | 30 | P30L | cCa | cTa | 1 | 1 | B.1.570 | 0.002941 |
ORF8 | 30 | P30L | cCa | cTa | 1 | 1 | B.1.581 | 0.009434 |
ORF8 | 30 | P30L | cCa | cTa | 1 | 1 | B.1.582 | 0.000491 |
ORF8 | 30 | P30L | cCa | cTa | 1 | 1 | B.1.590 | 0.004545 |
ORF8 | 30 | P30L | cCa | cTa | 1 | 1 | B.1.595 | 0.000261 |
ORF8 | 30 | P30L | cCa | cTa | 1 | 1 | B.1.595.1 | 0.005848 |
ORF8 | 30 | P30L | cCa | cTa | 1 | 1 | B.1.596 | 0.000087 |
ORF8 | 30 | P30L | cCa | cTa | 1 | 1 | B.1.617.1 | 0.000129 |
ORF8 | 30 | P30L | cCa | cTa | 1 | 1 | B.1.621 | 0.000089 |
ORF8 | 30 | P30L | cCa | cTa | 1 | 1 | B.1.621.1 | 0.000506 |
ORF8 | 30 | P30L | cCa | cTa | 1 | 1 | B.1.623 | 0.000536 |
ORF8 | 30 | P30L | cCa | cTa | 1 | 1 | B.6 | 0.00091 |
ORF8 | 30 | P30L | cCa | cTa | 1 | 1 | C.36 | 0.000911 |
ORF8 | 30 | P30L | cCa | cTa | 1 | 1 | P.1.10 | 0.000269 |
ORF8 | 30 | P30L | cCa | cTa | 1 | 1 | P.1.2 | 0.001156 |
ORF8 | 30 | P30L | cCa | cTa | 1 | 1 | Q.1 | 0.000126 |
ORF8 | 30 | P30L | cCa | cTa | 1 | 1 | Q.8 | 0.000165 |
CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk
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