CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF8 : Mut = L84S

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF884L84SnonsyntTatCa16874168730.99994128143-28145
ORF884L84SnonsyntTAtCG1687410.000059262828143-28145

Details of the mutation L84S within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF884L84StTatCa1687316874All0.003227
ORF884L84StTAtCG116874All0
ORF884L84StTatCa35233523A.10.992954
ORF884L84StTatCa23302330A0.901703
ORF884L84StTatCa19641964A.2.50.98004
ORF884L84StTatCa14951495A.20.989411
ORF884L84StTatCa14131413A.23.10.99507
ORF884L84StTatCa626626A.2.5.20.984277
ORF884L84StTatCa600600A.270.993377
ORF884L84StTatCa590590A.2.20.996622
ORF884L84StTatCa517517A.50.994231
ORF884L84StTatCa473473A.30.991614
ORF884L84StTatCa376376A.280.994709
ORF884L84StTatCa358358A.210.99169
ORF884L84StTatCa296296A.2.40.996633
ORF884L84StTatCa225225B0.028758
ORF884L84StTatCa207207A.2.30.981043
ORF884L84StTatCa207207A.2.5.10.995192
ORF884L84StTatCa195195A.61
ORF884L84StTatCa187187A.290.994681
ORF884L84StTatCa115115B.10.001053
ORF884L84StTatCa106106A.191
ORF884L84StTatCa9595A.2.5.30.979381
ORF884L84StTatCa9292A.230.968421
ORF884L84StTatCa8383AY.40.000129
ORF884L84StTatCa7878A.41
ORF884L84StTatCa6363A.151
ORF884L84StTatCa6262A.161
ORF884L84StTatCa5555A.251
ORF884L84StTatCa5051B.1.1.70.000045
ORF884L84StTAtCG151B.1.1.70.000001
ORF884L84StTatCa5050B.1.1.3180.015088
ORF884L84StTatCa4545B.1.177.810.00852
ORF884L84StTatCa2626AY.1200.000967
ORF884L84StTatCa2222A.91
ORF884L84StTatCa2020A.181
ORF884L84StTatCa1717A.111
ORF884L84StTatCa1717A.70.944444
ORF884L84StTatCa1717B.1.10.000308
ORF884L84StTatCa1515A.221
ORF884L84StTatCa1414A.241
ORF884L84StTatCa1414AY.440.000085
ORF884L84StTatCa1313A.261
ORF884L84StTatCa1313B.1.177.540.007884
ORF884L84StTatCa1111A.171
ORF884L84StTatCa1111B.1.617.20.000041
ORF884L84StTatCa1010B.1.617.10.00129
ORF884L84StTatCa88AY.30.00008
ORF884L84StTatCa77A.301
ORF884L84StTatCa77AY.1030.000043
ORF884L84StTatCa77B.1.20.000062
ORF884L84StTatCa66A.121
ORF884L84StTatCa66AY.1020.000159
ORF884L84StTatCa66AY.46.20.003812
ORF884L84StTatCa66B.1.3510.000178
ORF884L84StTatCa66B.1.6210.000531
ORF884L84StTatCa55AY.340.000485
ORF884L84StTatCa55B.1.1.4320.006329
ORF884L84StTatCa44B.1.1770.000053
ORF884L84StTatCa44B.1.2390.004884
ORF884L84StTatCa44B.1.4290.000094
ORF884L84StTatCa44B.1.5260.000094
ORF884L84StTatCa44P.10.000063
ORF884L84StTatCa33AY.1130.000427
ORF884L84StTatCa33AY.250.000018
ORF884L84StTatCa33AY.430.000013
ORF884L84StTatCa33B.1.1.2650.009464
ORF884L84StTatCa33B.1.1.5190.000119
ORF884L84StTatCa33B.1.5760.00272
ORF884L84StTatCa22AD.20.000438
ORF884L84StTatCa22AY.1170.000169
ORF884L84StTatCa22AY.130.000322
ORF884L84StTatCa22AY.4.20.000043
ORF884L84StTatCa22AY.60.000082
ORF884L84StTatCa22B.1.1.10.000653
ORF884L84StTatCa22B.1.1.630.000772
ORF884L84StTatCa22B.1.1390.001466
ORF884L84StTatCa22B.1.2340.000264
ORF884L84StTatCa22B.1.2470.029851
ORF884L84StTatCa22B.1.36.80.002
ORF884L84StTatCa11AT.10.005128
ORF884L84StTatCa11AY.200.000039
ORF884L84StTatCa11AY.270.000065
ORF884L84StTatCa11AY.280.00189
ORF884L84StTatCa11AY.420.00004
ORF884L84StTatCa11AY.460.000104
ORF884L84StTatCa11AY.480.000465
ORF884L84StTatCa11AY.5.30.000337
ORF884L84StTatCa11AY.540.000095
ORF884L84StTatCa11AY.620.000436
ORF884L84StTatCa11AY.650.000533
ORF884L84StTatCa11AY.700.000209
ORF884L84StTatCa11AY.900.000684
ORF884L84StTatCa11AY.99.20.000092
ORF884L84StTatCa11B.1.1.1610.003534
ORF884L84StTatCa11B.1.1.2200.001859
ORF884L84StTatCa11B.1.1.2220.000204
ORF884L84StTatCa11B.1.1.260.005236
ORF884L84StTatCa11B.1.1.390.00051
ORF884L84StTatCa11B.1.1.40.002976
ORF884L84StTatCa11B.1.1.5070.008696
ORF884L84StTatCa11B.1.1130.015625
ORF884L84StTatCa11B.1.1280.000635
ORF884L84StTatCa11B.1.1600.000031
ORF884L84StTatCa11B.1.160.330.004425
ORF884L84StTatCa11B.1.177.70.000165
ORF884L84StTatCa11B.1.177.730.000566
ORF884L84StTatCa11B.1.2060.000816
ORF884L84StTatCa11B.1.2210.000071
ORF884L84StTatCa11B.1.221.30.000833
ORF884L84StTatCa11B.1.2430.00007
ORF884L84StTatCa11B.1.3190.003049
ORF884L84StTatCa11B.1.36.220.001208
ORF884L84StTatCa11B.1.4090.000781
ORF884L84StTatCa11B.1.4370.020833
ORF884L84StTatCa11B.1.4970.000315
ORF884L84StTatCa11B.1.5240.001406
ORF884L84StTatCa11B.1.5960.000087
ORF884L84StTatCa11B.1.6090.000479
ORF884L84StTatCa11B.1.6270.00202
ORF884L84StTatCa11B.1.6280.000352
ORF884L84StTatCa11B.40.002208
ORF884L84StTatCa11B.400.000364
ORF884L84StTatCa11B.60.00091
ORF884L84StTatCa11C.370.000116
ORF884L84StTatCa11P.1.10.000318
ORF884L84StTatCa11P.1.70.000319
ORF884L84StTatCa11Q.20.000613

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

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