CoV-GLUE Mutation

CoV-GLUE Mutation: ORF = ORF8 : CodonNum = 92 & Codon = Aaa

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORF	CodonNum	Mut	ORF1abMut	MutType	RefCodon	MutCodon	AACount	CodonCount	CodonProp	Genome Position
ORF8	92	E92K		nonsyn	Gaa	Aaa	115970	115968	0.999983	28167-28169

Details of the mutation no within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORF	CodonNum	Mut	RefCodon	MutCodon	CodonCount	AACount	Lineage	LineageCodonProp
ORF8	92	E92K	Gaa	Aaa	115968	115970	All	0.02218
ORF8	92	E92K	Gaa	Aaa	62177	62179	P.1	0.979536
ORF8	92	E92K	Gaa	Aaa	20740	20740	P.1.14	0.991396
ORF8	92	E92K	Gaa	Aaa	6141	6141	P.1.17	0.993368
ORF8	92	E92K	Gaa	Aaa	4274	4274	P.1.15	0.99303
ORF8	92	E92K	Gaa	Aaa	3688	3688	P.1.10	0.993802
ORF8	92	E92K	Gaa	Aaa	3091	3091	P.1.7	0.986909
ORF8	92	E92K	Gaa	Aaa	2844	2844	P.1.1	0.903431
ORF8	92	E92K	Gaa	Aaa	2573	2573	P.1.16	0.962589
ORF8	92	E92K	Gaa	Aaa	1969	1969	P.1.12	0.953049
ORF8	92	E92K	Gaa	Aaa	1411	1411	A.23.1	0.993662
ORF8	92	E92K	Gaa	Aaa	1141	1141	P.1.17.1	0.99825
ORF8	92	E92K	Gaa	Aaa	1101	1101	P.1.13	0.989218
ORF8	92	E92K	Gaa	Aaa	1024	1024	P.1.4	1
ORF8	92	E92K	Gaa	Aaa	850	850	P.1.2	0.982659
ORF8	92	E92K	Gaa	Aaa	514	514	P.1.6	1
ORF8	92	E92K	Gaa	Aaa	438	438	A	0.169505
ORF8	92	E92K	Gaa	Aaa	207	207	P.1.8	0.990431
ORF8	92	E92K	Gaa	Aaa	206	206	P.1.9	0.990385
ORF8	92	E92K	Gaa	Aaa	182	182	A.29	0.968085
ORF8	92	E92K	Gaa	Aaa	164	164	B.1.1.7	0.000147
ORF8	92	E92K	Gaa	Aaa	138	138	B.1	0.001264
ORF8	92	E92K	Gaa	Aaa	121	121	P.1.10.1	0.98374
ORF8	92	E92K	Gaa	Aaa	110	110	B.1.1	0.001996
ORF8	92	E92K	Gaa	Aaa	97	97	P.1.11	0.989796
ORF8	92	E92K	Gaa	Aaa	94	94	A.23	0.989474
ORF8	92	E92K	Gaa	Aaa	63	63	A.15	1
ORF8	92	E92K	Gaa	Aaa	55	55	A.25	1
ORF8	92	E92K	Gaa	Aaa	43	43	C.37	0.004991
ORF8	92	E92K	Gaa	Aaa	34	34	B.1.617.2	0.000128
ORF8	92	E92K	Gaa	Aaa	32	32	B.1.1.222	0.006528
ORF8	92	E92K	Gaa	Aaa	29	29	P.1.3	1
ORF8	92	E92K	Gaa	Aaa	25	25	B.1.1.528	0.120192
ORF8	92	E92K	Gaa	Aaa	24	24	B.1.234	0.003167
ORF8	92	E92K	Gaa	Aaa	24	24	P.1.10.2	1
ORF8	92	E92K	Gaa	Aaa	23	23	AY.4	0.000036
ORF8	92	E92K	Gaa	Aaa	18	18	B.1.1.28	0.005602
ORF8	92	E92K	Gaa	Aaa	16	16	B.1.621	0.001416
ORF8	92	E92K	Gaa	Aaa	14	14	AY.103	0.000087
ORF8	92	E92K	Gaa	Aaa	13	13	A.24	0.928571
ORF8	92	E92K	Gaa	Aaa	13	13	A.26	1
ORF8	92	E92K	Gaa	Aaa	13	13	P.1.5	1
ORF8	92	E92K	Gaa	Aaa	10	10	AY.119	0.000353
ORF8	92	E92K	Gaa	Aaa	9	9	A.2.5	0.004491
ORF8	92	E92K	Gaa	Aaa	9	9	AY.44	0.000055
ORF8	92	E92K	Gaa	Aaa	9	9	B.1.2	0.000079
ORF8	92	E92K	Gaa	Aaa	8	8	C.37.1	0.020942
ORF8	92	E92K	Gaa	Aaa	6	6	A.30	0.857143
ORF8	92	E92K	Gaa	Aaa	6	6	AY.23	0.000418
ORF8	92	E92K	Gaa	Aaa	6	6	B	0.000767
ORF8	92	E92K	Gaa	Aaa	6	6	B.1.427	0.000303
ORF8	92	E92K	Gaa	Aaa	5	5	AY.43	0.000022
ORF8	92	E92K	Gaa	Aaa	5	5	B.1.1.519	0.000199
ORF8	92	E92K	Gaa	Aaa	5	5	C.35	0.00387
ORF8	92	E92K	Gaa	Aaa	4	4	AY.100	0.000184
ORF8	92	E92K	Gaa	Aaa	4	4	B.1.1.507	0.034783
ORF8	92	E92K	Gaa	Aaa	4	4	B.1.311	0.001098
ORF8	92	E92K	Gaa	Aaa	3	3	A.21	0.00831
ORF8	92	E92K	Gaa	Aaa	3	3	AY.20	0.000117
ORF8	92	E92K	Gaa	Aaa	3	3	AY.25	0.000018
ORF8	92	E92K	Gaa	Aaa	3	3	AY.26	0.000085
ORF8	92	E92K	Gaa	Aaa	3	3	AY.47	0.000093
ORF8	92	E92K	Gaa	Aaa	3	3	B.1.1.161	0.010601
ORF8	92	E92K	Gaa	Aaa	3	3	B.1.1.348	0.002389
ORF8	92	E92K	Gaa	Aaa	3	3	B.1.1.372	0.002066
ORF8	92	E92K	Gaa	Aaa	3	3	B.1.177.7	0.000495
ORF8	92	E92K	Gaa	Aaa	3	3	B.1.533	0.028846
ORF8	92	E92K	Gaa	Aaa	3	3	C.30	0.005181
ORF8	92	E92K	Gaa	Aaa	2	2	A.1	0.000564
ORF8	92	E92K	Gaa	Aaa	2	2	A.27	0.003311
ORF8	92	E92K	Gaa	Aaa	2	2	AY.102	0.000053
ORF8	92	E92K	Gaa	Aaa	2	2	AY.117	0.000169
ORF8	92	E92K	Gaa	Aaa	2	2	AY.118	0.000125
ORF8	92	E92K	Gaa	Aaa	2	2	AY.3	0.00002
ORF8	92	E92K	Gaa	Aaa	2	2	AY.74	0.000231
ORF8	92	E92K	Gaa	Aaa	2	2	B.1.1.117	0.019417
ORF8	92	E92K	Gaa	Aaa	2	2	B.1.1.220	0.003717
ORF8	92	E92K	Gaa	Aaa	2	2	B.1.1.265	0.006309
ORF8	92	E92K	Gaa	Aaa	2	2	B.1.1.409	0.005666
ORF8	92	E92K	Gaa	Aaa	2	2	B.1.160	0.000062
ORF8	92	E92K	Gaa	Aaa	2	2	B.1.177	0.000026
ORF8	92	E92K	Gaa	Aaa	2	2	B.1.177.73	0.001133
ORF8	92	E92K	Gaa	Aaa	2	2	B.1.179	0.007519
ORF8	92	E92K	Gaa	Aaa	2	2	B.1.221	0.000142
ORF8	92	E92K	Gaa	Aaa	2	2	B.1.258	0.000133
ORF8	92	E92K	Gaa	Aaa	2	2	B.1.324	0.00321
ORF8	92	E92K	Gaa	Aaa	2	2	B.1.351	0.000059
ORF8	92	E92K	Gaa	Aaa	2	2	B.1.375	0.001639
ORF8	92	E92K	Gaa	Aaa	2	2	B.1.429	0.000047
ORF8	92	E92K	Gaa	Aaa	2	2	B.1.526	0.000047
ORF8	92	E92K	Gaa	Aaa	2	2	B.1.596	0.000174
ORF8	92	E92K	Gaa	Aaa	2	2	B.1.623	0.001073
ORF8	92	E92K	Gaa	Aaa	2	2	P.2	0.000373
ORF8	92	E92K	Gaa	Aaa	2	2	Q.1	0.000253
ORF8	92	E92K	Gaa	Aaa	1	1	A.19	0.009434
ORF8	92	E92K	Gaa	Aaa	1	1	A.2	0.000662
ORF8	92	E92K	Gaa	Aaa	1	1	AY.113	0.000142
ORF8	92	E92K	Gaa	Aaa	1	1	AY.116	0.000287
ORF8	92	E92K	Gaa	Aaa	1	1	AY.120	0.000037
ORF8	92	E92K	Gaa	Aaa	1	1	AY.2	0.000356
ORF8	92	E92K	Gaa	Aaa	1	1	AY.29	0.000016
ORF8	92	E92K	Gaa	Aaa	1	1	AY.3.1	0.000085
ORF8	92	E92K	Gaa	Aaa	1	1	AY.33	0.000067
ORF8	92	E92K	Gaa	Aaa	1	1	AY.34	0.000097
ORF8	92	E92K	Gaa	Aaa	1	1	AY.35	0.000233
ORF8	92	E92K	Gaa	Aaa	1	1	AY.4.2.1	0.000149
ORF8	92	E92K	Gaa	Aaa	1	1	AY.45	0.000122
ORF8	92	E92K	Gaa	Aaa	1	1	AY.5	0.000021
ORF8	92	E92K	Gaa	Aaa	1	1	AY.5.3	0.000337
ORF8	92	E92K	Gaa	Aaa	1	1	AY.54	0.000095
ORF8	92	E92K	Gaa	Aaa	1	1	AY.61	0.000105
ORF8	92	E92K	Gaa	Aaa	1	1	AY.62	0.000436
ORF8	92	E92K	Gaa	Aaa	1	1	AY.7	0.000196
ORF8	92	E92K	Gaa	Aaa	1	1	AY.75.1	0.00018
ORF8	92	E92K	Gaa	Aaa	1	1	AY.9.2	0.000037
ORF8	92	E92K	Gaa	Aaa	1	1	AY.99.2	0.000092
ORF8	92	E92K	Gaa	Aaa	1	1	B.1.1.121	0.002427
ORF8	92	E92K	Gaa	Aaa	1	1	B.1.1.214	0.000055
ORF8	92	E92K	Gaa	Aaa	1	1	B.1.1.236	0.006897
ORF8	92	E92K	Gaa	Aaa	1	1	B.1.1.318	0.000302
ORF8	92	E92K	Gaa	Aaa	1	1	B.1.1.33	0.000421
ORF8	92	E92K	Gaa	Aaa	1	1	B.1.1.54	0.003021
ORF8	92	E92K	Gaa	Aaa	1	1	B.1.1.70	0.000341
ORF8	92	E92K	Gaa	Aaa	1	1	B.1.1.99	0.02381
ORF8	92	E92K	Gaa	Aaa	1	1	B.1.170	0.00431
ORF8	92	E92K	Gaa	Aaa	1	1	B.1.214	0.003663
ORF8	92	E92K	Gaa	Aaa	1	1	B.1.214.2	0.0006
ORF8	92	E92K	Gaa	Aaa	1	1	B.1.239	0.001221
ORF8	92	E92K	Gaa	Aaa	1	1	B.1.241	0.000812
ORF8	92	E92K	Gaa	Aaa	1	1	B.1.349	0.000715
ORF8	92	E92K	Gaa	Aaa	1	1	B.1.369	0.000285
ORF8	92	E92K	Gaa	Aaa	1	1	B.1.397	0.004854
ORF8	92	E92K	Gaa	Aaa	1	1	B.1.399	0.001934
ORF8	92	E92K	Gaa	Aaa	1	1	B.1.521	0.004975
ORF8	92	E92K	Gaa	Aaa	1	1	B.1.525	0.000113
ORF8	92	E92K	Gaa	Aaa	1	1	B.1.582	0.000491
ORF8	92	E92K	Gaa	Aaa	1	1	B.1.595	0.000261
ORF8	92	E92K	Gaa	Aaa	1	1	B.1.609	0.000479
ORF8	92	E92K	Gaa	Aaa	1	1	B.1.620	0.000946
ORF8	92	E92K	Gaa	Aaa	1	1	B.1.627	0.00202
ORF8	92	E92K	Gaa	Aaa	1	1	B.1.636	0.006711
ORF8	92	E92K	Gaa	Aaa	1	1	B.1.637	0.000073
ORF8	92	E92K	Gaa	Aaa	1	1	B.4	0.002208
ORF8	92	E92K	Gaa	Aaa	1	1	B.55	0.00295
ORF8	92	E92K	Gaa	Aaa	1	1	C.39	0.018868
ORF8	92	E92K	Gaa	Aaa	1	1	N.5	0.001767
ORF8	92	E92K	Gaa	Aaa	1	1	P.7	0.004367

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.