CoV-GLUE Mutation

CoV-GLUE Mutation: ORF = ORF8 : CodonNum = 90

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORF	CodonNum	Mut	ORF1abMut	MutType	RefCodon	MutCodon	AACount	CodonCount	CodonProp	Genome Position
ORF8	90	C90C		syn	tgC	tgT	1111	1111	1	28161-28163
ORF8	90	C90F		nonsyn	tGc	tTc	888	799	0.899775	28161-28163
ORF8	90	C90F		nonsyn	tGC	tTT	888	89	0.100225	28161-28163
ORF8	90	C90del		del	TGC	---	564	564	1	28161-28163
ORF8	90	C90Y		nonsyn	tGc	tAc	305	233	0.763934	28161-28163
ORF8	90	C90Y		nonsyn	tGC	tAT	305	72	0.236066	28161-28163
ORF8	90	C90I		nonsyn	TGC	ATT	166	76	0.457831	28161-28163
ORF8	90	C90I		nonsyn	TGC	ATA	166	72	0.433735	28161-28163
ORF8	90	C90I		nonsyn	TGc	ATc	166	18	0.108434	28161-28163
ORF8	90	C90del1		del	Tgc	-gc	164	156	0.951219	28161-28163
ORF8	90	C90del1		del	tgC	tg-	164	8	0.0487805	28161-28163
ORF8	90	C90X		nonsyn	tgC	tgA	144	74	0.513889	28161-28163
ORF8	90	C90S		nonsyn	tGc	tCc	144	72	0.5	28161-28163
ORF8	90	C90X		nonsyn	tGC	tAA	144	69	0.479167	28161-28163
ORF8	90	C90S		nonsyn	Tgc	Agc	144	35	0.243056	28161-28163
ORF8	90	C90S		nonsyn	TgC	AgT	144	19	0.131944	28161-28163
ORF8	90	C90S		nonsyn	tGC	tCT	144	10	0.0694444	28161-28163
ORF8	90	C90S		nonsyn	tGC	tCA	144	7	0.0486111	28161-28163
ORF8	90	C90X		nonsyn	tGC	tAG	144	1	0.00694444	28161-28163
ORF8	90	C90S		nonsyn	tGC	tCG	144	1	0.00694444	28161-28163
ORF8	90	C90L		nonsyn	tGC	tTA	87	71	0.816092	28161-28163
ORF8	90	C90L		nonsyn	TGC	CTT	87	7	0.0804598	28161-28163
ORF8	90	C90L		nonsyn	TGC	CTA	87	5	0.0574713	28161-28163
ORF8	90	C90L		nonsyn	TGc	CTc	87	3	0.0344828	28161-28163
ORF8	90	C90L		nonsyn	tGC	tTG	87	1	0.0114943	28161-28163
ORF8	90	C90N		nonsyn	TGC	AAT	79	68	0.860759	28161-28163
ORF8	90	C90N		nonsyn	TGc	AAc	79	11	0.139241	28161-28163
ORF8	90	C90K		nonsyn	TGC	AAA	71	70	0.985915	28161-28163
ORF8	90	C90K		nonsyn	TGC	AAG	71	1	0.0140845	28161-28163
ORF8	90	C90R		nonsyn	Tgc	Cgc	52	36	0.692308	28161-28163
ORF8	90	C90R		nonsyn	TgC	AgA	52	13	0.25	28161-28163
ORF8	90	C90R		nonsyn	TgC	CgA	52	1	0.0192308	28161-28163
ORF8	90	C90R		nonsyn	TgC	CgG	52	1	0.0192308	28161-28163
ORF8	90	C90R		nonsyn	TgC	CgT	52	1	0.0192308	28161-28163
ORF8	90	C90V		nonsyn	TGC	GTT	23	11	0.478261	28161-28163
ORF8	90	C90V		nonsyn	TGC	GTA	23	8	0.347826	28161-28163
ORF8	90	C90V		nonsyn	TGc	GTc	23	4	0.173913	28161-28163
ORF8	90	C90G		nonsyn	Tgc	Ggc	18	10	0.555556	28161-28163
ORF8	90	C90G		nonsyn	TgC	GgT	18	6	0.333333	28161-28163
ORF8	90	C90G		nonsyn	TgC	GgA	18	2	0.111111	28161-28163
ORF8	90	C90T		nonsyn	TGC	ACA	12	6	0.5	28161-28163
ORF8	90	C90T		nonsyn	TGC	ACT	12	3	0.25	28161-28163
ORF8	90	C90T		nonsyn	TGc	ACc	12	2	0.166667	28161-28163
ORF8	90	C90T		nonsyn	TGC	ACG	12	1	0.0833333	28161-28163
ORF8	90	C90D		nonsyn	TGC	GAT	11	9	0.818182	28161-28163
ORF8	90	C90D		nonsyn	TGc	GAc	11	2	0.181818	28161-28163
ORF8	90	C90H		nonsyn	TGC	CAT	10	6	0.6	28161-28163
ORF8	90	C90H		nonsyn	TGc	CAc	10	4	0.4	28161-28163
ORF8	90	C90del2		del	TGc	--c	8	6	0.75	28161-28163
ORF8	90	C90del2		del	TGC	--N	8	1	0.125	28161-28163
ORF8	90	C90del2		del	tGC	t--	8	1	0.125	28161-28163
ORF8	90	C90E		nonsyn	TGC	GAA	7	7	1	28161-28163
ORF8	90	C90Q		nonsyn	TGC	CAA	6	6	1	28161-28163
ORF8	90	C90W		nonsyn	tgC	tgG	2	2	1	28161-28163
ORF8	90	C90A		nonsyn	TGC	GCT	2	1	0.5	28161-28163
ORF8	90	C90A		nonsyn	TGC	GCA	2	1	0.5	28161-28163
ORF8	90	C90M		nonsyn	TGC	ATG	1	1	1	28161-28163

Details of the mutation no within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORF	CodonNum	Mut	RefCodon	MutCodon	CodonCount	AACount	Lineage	LineageCodonProp
ORF8	90	C90C	tgC	tgT	1111	1111	All	0.000212
ORF8	90	C90F	tGc	tTc	799	888	All	0.000153
ORF8	90	C90F	tGC	tTT	89	888	All	0.000017
ORF8	90	C90del	TGC	---	564	564	All	0.000108
ORF8	90	C90F	tGc	tTc	367	448	B.1.1.7	0.000329
ORF8	90	C90F	tGC	tTT	81	448	B.1.1.7	0.000073
ORF8	90	C90Y	tGc	tAc	233	305	All	0.000045
ORF8	90	C90Y	tGC	tAT	72	305	All	0.000014
ORF8	90	C90C	tgC	tgT	190	190	B.1.1.7	0.00017
ORF8	90	C90I	TGC	ATT	76	166	All	0.000015
ORF8	90	C90I	TGC	ATA	72	166	All	0.000014
ORF8	90	C90I	TGc	ATc	18	166	All	0.000003
ORF8	90	C90del1	Tgc	-gc	156	164	All	0.00003
ORF8	90	C90del1	tgC	tg-	8	164	All	0.000002
ORF8	90	C90C	tgC	tgT	160	160	B.1.617.2	0.000602
ORF8	90	C90I	TGC	ATT	71	156	B.1.1.7	0.000064
ORF8	90	C90I	TGC	ATA	68	156	B.1.1.7	0.000061
ORF8	90	C90I	TGc	ATc	17	156	B.1.1.7	0.000015
ORF8	90	C90del1	Tgc	-gc	154	154	B.1.1.7	0.000138
ORF8	90	C90X	tgC	tgA	74	144	All	0.000014
ORF8	90	C90S	tGc	tCc	72	144	All	0.000014
ORF8	90	C90X	tGC	tAA	69	144	All	0.000013
ORF8	90	C90S	Tgc	Agc	35	144	All	0.000007
ORF8	90	C90S	TgC	AgT	19	144	All	0.000004
ORF8	90	C90S	tGC	tCT	10	144	All	0.000002
ORF8	90	C90S	tGC	tCA	7	144	All	0.000001
ORF8	90	C90X	tGC	tAG	1	144	All	0
ORF8	90	C90S	tGC	tCG	1	144	All	0
ORF8	90	C90Y	tGC	tAT	67	117	B.1.1.7	0.00006
ORF8	90	C90Y	tGc	tAc	50	117	B.1.1.7	0.000045
ORF8	90	C90C	tgC	tgT	114	114	AY.100	0.005245
ORF8	90	C90S	tGc	tCc	59	111	B.1.1.7	0.000053
ORF8	90	C90S	Tgc	Agc	23	111	B.1.1.7	0.000021
ORF8	90	C90S	TgC	AgT	16	111	B.1.1.7	0.000014
ORF8	90	C90S	tGC	tCA	7	111	B.1.1.7	0.000006
ORF8	90	C90S	tGC	tCT	5	111	B.1.1.7	0.000004
ORF8	90	C90S	tGC	tCG	1	111	B.1.1.7	0.000001
ORF8	90	C90F	tGc	tTc	104	104	AY.4	0.000162
ORF8	90	C90X	tGC	tAA	64	88	B.1.1.7	0.000057
ORF8	90	C90X	tgC	tgA	23	88	B.1.1.7	0.000021
ORF8	90	C90X	tGC	tAG	1	88	B.1.1.7	0.000001
ORF8	90	C90L	tGC	tTA	71	87	All	0.000014
ORF8	90	C90L	TGC	CTT	7	87	All	0.000001
ORF8	90	C90L	TGC	CTA	5	87	All	0.000001
ORF8	90	C90L	TGc	CTc	3	87	All	0.000001
ORF8	90	C90L	tGC	tTG	1	87	All	0
ORF8	90	C90L	tGC	tTA	67	83	B.1.1.7	0.00006
ORF8	90	C90L	TGC	CTT	7	83	B.1.1.7	0.000006
ORF8	90	C90L	TGC	CTA	5	83	B.1.1.7	0.000004
ORF8	90	C90L	TGc	CTc	3	83	B.1.1.7	0.000003
ORF8	90	C90L	tGC	tTG	1	83	B.1.1.7	0.000001
ORF8	90	C90del	TGC	---	82	82	B.1.1.7	0.000073
ORF8	90	C90N	TGC	AAT	68	79	All	0.000013
ORF8	90	C90N	TGc	AAc	11	79	All	0.000002
ORF8	90	C90C	tgC	tgT	79	79	AY.61	0.008277
ORF8	90	C90N	TGC	AAT	63	73	B.1.1.7	0.000056
ORF8	90	C90N	TGc	AAc	10	73	B.1.1.7	0.000009
ORF8	90	C90K	TGC	AAA	70	71	All	0.000013
ORF8	90	C90K	TGC	AAG	1	71	All	0
ORF8	90	C90F	tGc	tTc	70	70	AY.103	0.000435
ORF8	90	C90Y	tGc	tAc	69	69	B.1.617.2	0.00026
ORF8	90	C90K	TGC	AAA	66	67	B.1.1.7	0.000059
ORF8	90	C90K	TGC	AAG	1	67	B.1.1.7	0.000001
ORF8	90	C90del	TGC	---	59	59	B.1.1.294	0.074684
ORF8	90	C90del	TGC	---	57	57	AY.4	0.000089
ORF8	90	C90C	tgC	tgT	53	53	B.1.305	0.113978
ORF8	90	C90R	Tgc	Cgc	36	52	All	0.000007
ORF8	90	C90R	TgC	AgA	13	52	All	0.000002
ORF8	90	C90R	TgC	CgG	1	52	All	0
ORF8	90	C90R	TgC	CgT	1	52	All	0
ORF8	90	C90R	TgC	CgA	1	52	All	0
ORF8	90	C90C	tgC	tgT	52	52	B.1.348	0.945455
ORF8	90	C90C	tgC	tgT	43	43	AY.4	0.000067
ORF8	90	C90del	TGC	---	37	37	AY.29	0.000584
ORF8	90	C90Y	tGc	tAc	35	35	AY.43	0.000155
ORF8	90	C90del	TGC	---	34	34	B.1.243	0.002366
ORF8	90	C90del	TGC	---	33	33	B.1.1.222	0.006732
ORF8	90	C90F	tGc	tTc	33	33	B.1.617.2	0.000124
ORF8	90	C90del	TGC	---	29	29	B.1.1	0.000526
ORF8	90	C90R	Tgc	Cgc	16	29	B.1.1.7	0.000014
ORF8	90	C90R	TgC	AgA	11	29	B.1.1.7	0.00001
ORF8	90	C90R	TgC	CgA	1	29	B.1.1.7	0.000001
ORF8	90	C90R	TgC	CgT	1	29	B.1.1.7	0.000001
ORF8	90	C90del	TGC	---	27	27	AY.103	0.000168
ORF8	90	C90C	tgC	tgT	24	24	B.1.160	0.000749
ORF8	90	C90V	TGC	GTT	11	23	All	0.000002
ORF8	90	C90V	TGC	GTA	8	23	All	0.000002
ORF8	90	C90V	TGc	GTc	4	23	All	0.000001
ORF8	90	C90V	TGC	GTT	11	23	B.1.1.7	0.00001
ORF8	90	C90V	TGC	GTA	8	23	B.1.1.7	0.000007
ORF8	90	C90V	TGc	GTc	4	23	B.1.1.7	0.000004
ORF8	90	C90C	tgC	tgT	21	21	AY.103	0.00013
ORF8	90	C90C	tgC	tgT	20	20	AY.29	0.000315
ORF8	90	C90X	tgC	tgA	20	20	AY.4	0.000031
ORF8	90	C90F	tGc	tTc	19	19	AY.44	0.000116
ORF8	90	C90G	Tgc	Ggc	10	18	All	0.000002
ORF8	90	C90G	TgC	GgT	6	18	All	0.000001
ORF8	90	C90G	TgC	GgA	2	18	All	0
ORF8	90	C90F	tGc	tTc	18	18	AY.74	0.002082
ORF8	90	C90del	TGC	---	18	18	B	0.002301
ORF8	90	C90C	tgC	tgT	18	18	B.1.36	0.002626
ORF8	90	C90C	tgC	tgT	18	18	B.1.637	0.001315
ORF8	90	C90C	tgC	tgT	17	17	B.1	0.000156
ORF8	90	C90del	TGC	---	16	16	AY.25	0.000096
ORF8	90	C90F	tGc	tTc	16	16	AY.27	0.001036
ORF8	90	C90C	tgC	tgT	16	16	AY.4.2	0.000347
ORF8	90	C90F	tGc	tTc	14	14	AY.43	0.000062
ORF8	90	C90C	tgC	tgT	13	13	AY.25	0.000078
ORF8	90	C90C	tgC	tgT	13	13	B.1.1	0.000236
ORF8	90	C90C	tgC	tgT	13	13	B.1.2	0.000114
ORF8	90	C90C	tgC	tgT	13	13	B.1.221	0.000923
ORF8	90	C90del	TGC	---	13	13	B.1.617.2	0.000049
ORF8	90	C90T	TGC	ACA	6	12	All	0.000001
ORF8	90	C90T	TGC	ACT	3	12	All	0.000001
ORF8	90	C90T	TGc	ACc	2	12	All	0
ORF8	90	C90T	TGC	ACG	1	12	All	0
ORF8	90	C90F	tGc	tTc	11	12	AY.25	0.000066
ORF8	90	C90F	tGC	tTT	1	12	AY.25	0.000006
ORF8	90	C90C	tgC	tgT	12	12	AY.44	0.000073
ORF8	90	C90C	tgC	tgT	12	12	AY.47	0.000373
ORF8	90	C90T	TGC	ACA	6	12	B.1.1.7	0.000005
ORF8	90	C90T	TGC	ACT	3	12	B.1.1.7	0.000003
ORF8	90	C90T	TGc	ACc	2	12	B.1.1.7	0.000002
ORF8	90	C90T	TGC	ACG	1	12	B.1.1.7	0.000001
ORF8	90	C90del	TGC	---	12	12	P.1	0.000189
ORF8	90	C90F	tGc	tTc	12	12	Q.3	0.00174
ORF8	90	C90D	TGC	GAT	9	11	All	0.000002
ORF8	90	C90D	TGc	GAc	2	11	All	0
ORF8	90	C90C	tgC	tgT	11	11	AY.102	0.000292
ORF8	90	C90Y	tGc	tAc	11	11	AY.39	0.000272
ORF8	90	C90D	TGC	GAT	9	11	B.1.1.7	0.000008
ORF8	90	C90G	TgC	GgT	5	11	B.1.1.7	0.000004
ORF8	90	C90G	Tgc	Ggc	4	11	B.1.1.7	0.000004
ORF8	90	C90D	TGc	GAc	2	11	B.1.1.7	0.000002
ORF8	90	C90G	TgC	GgA	2	11	B.1.1.7	0.000002
ORF8	90	C90H	TGC	CAT	6	10	All	0.000001
ORF8	90	C90H	TGc	CAc	4	10	All	0.000001
ORF8	90	C90Y	tGc	tAc	10	10	AY.44	0.000061
ORF8	90	C90del	TGC	---	10	10	B.1.160	0.000312
ORF8	90	C90F	tGc	tTc	10	10	B.1.630	0.052356
ORF8	90	C90C	tgC	tgT	9	9	AY.43	0.00004
ORF8	90	C90del	TGC	---	9	9	AY.43	0.00004
ORF8	90	C90H	TGC	CAT	6	9	B.1.1.7	0.000005
ORF8	90	C90H	TGc	CAc	3	9	B.1.1.7	0.000003
ORF8	90	C90del2	TGc	--c	6	8	All	0.000001
ORF8	90	C90del2	TGC	--N	1	8	All	0
ORF8	90	C90del2	tGC	t--	1	8	All	0
ORF8	90	C90C	tgC	tgT	8	8	AY.26	0.000226
ORF8	90	C90E	TGC	GAA	7	7	All	0.000001
ORF8	90	C90C	tgC	tgT	7	7	AY.20	0.000272
ORF8	90	C90C	tgC	tgT	7	7	AY.39.1	0.000277
ORF8	90	C90R	Tgc	Cgc	7	7	AY.4	0.000011
ORF8	90	C90C	tgC	tgT	7	7	AY.42	0.000282
ORF8	90	C90C	tgC	tgT	7	7	AY.9.2	0.000257
ORF8	90	C90F	tGc	tTc	5	7	B.1	0.000046
ORF8	90	C90F	tGC	tTT	2	7	B.1	0.000018
ORF8	90	C90del	TGC	---	7	7	B.1.1.265	0.022082
ORF8	90	C90C	tgC	tgT	7	7	B.1.1.28	0.002179
ORF8	90	C90del	TGC	---	7	7	B.1.1.284	0.000752
ORF8	90	C90C	tgC	tgT	7	7	B.1.1.33	0.002946
ORF8	90	C90C	tgC	tgT	7	7	B.1.1.63	0.002701
ORF8	90	C90E	TGC	GAA	7	7	B.1.1.7	0.000006
ORF8	90	C90C	tgC	tgT	7	7	B.1.234	0.000924
ORF8	90	C90del	TGC	---	7	7	B.1.36.16	0.009972
ORF8	90	C90Q	TGC	CAA	6	6	All	0.000001
ORF8	90	C90Y	tGc	tAc	6	6	AY.29	0.000095
ORF8	90	C90Q	TGC	CAA	6	6	B.1.1.7	0.000005
ORF8	90	C90C	tgC	tgT	6	6	B.1.258.17	0.000624
ORF8	90	C90C	tgC	tgT	6	6	B.1.351	0.000178
ORF8	90	C90del	TGC	---	6	6	P.1.14	0.000287
ORF8	90	C90del	TGC	---	5	5	AY.29.1	0.001103
ORF8	90	C90del	TGC	---	5	5	AY.3	0.00005
ORF8	90	C90F	tGc	tTc	5	5	AY.5	0.000103
ORF8	90	C90F	tGc	tTc	5	5	AY.9	0.000338
ORF8	90	C90S	tGc	tCc	4	5	B.1	0.000037
ORF8	90	C90S	tGC	tCT	1	5	B.1	0.000009
ORF8	90	C90X	tgC	tgA	4	5	B.1.1	0.000073
ORF8	90	C90X	tGC	tAA	1	5	B.1.1	0.000018
ORF8	90	C90C	tgC	tgT	5	5	B.1.177	0.000066
ORF8	90	C90F	tGc	tTc	5	5	B.1.2	0.000044
ORF8	90	C90C	tgC	tgT	5	5	B.1.206	0.004078
ORF8	90	C90S	Tgc	Agc	5	5	B.1.524	0.007032
ORF8	90	C90R	Tgc	Cgc	5	5	B.1.617.2	0.000019
ORF8	90	C90F	tGc	tTc	4	5	P.1	0.000063
ORF8	90	C90F	tGC	tTT	1	5	P.1	0.000016
ORF8	90	C90del	TGC	---	5	5	P.1.1	0.001588
ORF8	90	C90F	tGc	tTc	4	4	AY.102	0.000106
ORF8	90	C90Y	tGc	tAc	3	4	AY.25	0.000018
ORF8	90	C90Y	tGC	tAT	1	4	AY.25	0.000006
ORF8	90	C90F	tGc	tTc	4	4	AY.39	0.000099
ORF8	90	C90C	tgC	tgT	4	4	AY.5	0.000083
ORF8	90	C90X	tgC	tgA	4	4	AY.5	0.000083
ORF8	90	C90del	TGC	---	4	4	AY.75	0.000224
ORF8	90	C90F	tGc	tTc	4	4	AY.9.2	0.000147
ORF8	90	C90Y	tGC	tAT	2	4	B.1	0.000018
ORF8	90	C90I	TGC	ATA	2	4	B.1	0.000018
ORF8	90	C90I	TGC	ATT	2	4	B.1	0.000018
ORF8	90	C90Y	tGc	tAc	2	4	B.1	0.000018
ORF8	90	C90F	tGc	tTc	4	4	B.1.1	0.000073
ORF8	90	C90F	tGc	tTc	4	4	B.1.1.214	0.000222
ORF8	90	C90C	tgC	tgT	4	4	B.1.1.432	0.005063
ORF8	90	C90C	tgC	tgT	4	4	B.1.1.486	0.006309
ORF8	90	C90del	TGC	---	4	4	B.1.1.519	0.000159
ORF8	90	C90Y	tGc	tAc	4	4	B.1.177	0.000053
ORF8	90	C90del	TGC	---	4	4	B.1.2	0.000035
ORF8	90	C90del	TGC	---	4	4	B.1.320	0.004981
ORF8	90	C90C	tgC	tgT	4	4	B.1.375	0.003279
ORF8	90	C90C	tgC	tgT	4	4	B.1.429	0.000094
ORF8	90	C90F	tGc	tTc	4	4	B.1.526	0.000094
ORF8	90	C90Y	tGc	tAc	4	4	P.1.14	0.000191
ORF8	90	C90C	tgC	tgT	4	4	P.1.6	0.007782
ORF8	90	C90F	tGc	tTc	3	3	AY.100	0.000138
ORF8	90	C90Y	tGc	tAc	3	3	AY.103	0.000019
ORF8	90	C90del	TGC	---	3	3	AY.26	0.000085
ORF8	90	C90C	tgC	tgT	3	3	AY.33	0.0002
ORF8	90	C90C	tgC	tgT	3	3	AY.38	0.001498
ORF8	90	C90Y	tGc	tAc	3	3	AY.46.5	0.000595
ORF8	90	C90F	tGc	tTc	3	3	AY.6	0.000123
ORF8	90	C90X	tGC	tAA	2	3	B.1	0.000018
ORF8	90	C90X	tgC	tgA	1	3	B.1	0.000009
ORF8	90	C90Y	tGc	tAc	3	3	B.1.2	0.000026
ORF8	90	C90del	TGC	---	3	3	B.1.22	0.003953
ORF8	90	C90S	tGC	tCT	3	3	B.1.398	0.008929
ORF8	90	C90C	tgC	tgT	3	3	B.1.411	0.011111
ORF8	90	C90del	TGC	---	3	3	B.1.429	0.000071
ORF8	90	C90X	tgC	tgA	3	3	B.1.429	0.000071
ORF8	90	C90del	TGC	---	3	3	B.1.509	0.002597
ORF8	90	C90X	tgC	tgA	3	3	B.1.617.2	0.000011
ORF8	90	C90S	Tgc	Agc	2	3	B.1.621	0.000177
ORF8	90	C90S	tGC	tCT	1	3	B.1.621	0.000089
ORF8	90	C90F	tGc	tTc	3	3	D.2	0.000225
ORF8	90	C90C	tgC	tgT	3	3	P.1	0.000047
ORF8	90	C90del	TGC	---	3	3	P.1.2	0.003468
ORF8	90	C90Y	tGc	tAc	3	3	Q.3	0.000435
ORF8	90	C90F	tGC	tTT	2	2		0.111111
ORF8	90	C90F	tGc	tTc	2	2	A.2.5	0.000998
ORF8	90	C90W	tgC	tgG	2	2	All	0
ORF8	90	C90A	TGC	GCT	1	2	All	0
ORF8	90	C90A	TGC	GCA	1	2	All	0
ORF8	90	C90Y	tGc	tAc	2	2	AY.116	0.000574
ORF8	90	C90F	tGc	tTc	2	2	AY.117	0.000169
ORF8	90	C90del1	tgC	tg-	2	2	AY.119	0.000071
ORF8	90	C90S	tGc	tCc	2	2	AY.119	0.000071
ORF8	90	C90F	tGc	tTc	2	2	AY.16.1	0.00094
ORF8	90	C90F	tGc	tTc	2	2	AY.20	0.000078
ORF8	90	C90Y	tGc	tAc	2	2	AY.23	0.000139
ORF8	90	C90del1	Tgc	-gc	2	2	AY.25	0.000012
ORF8	90	C90G	Tgc	Ggc	2	2	AY.25	0.000012
ORF8	90	C90I	TGC	ATT	1	2	AY.25	0.000006
ORF8	90	C90I	TGC	ATA	1	2	AY.25	0.000006
ORF8	90	C90F	tGc	tTc	2	2	AY.26	0.000057
ORF8	90	C90F	tGc	tTc	2	2	AY.4.2	0.000043
ORF8	90	C90X	tgC	tgA	2	2	AY.43	0.000009
ORF8	90	C90del	TGC	---	2	2	AY.44	0.000012
ORF8	90	C90F	tGc	tTc	2	2	AY.46	0.000208
ORF8	90	C90C	tgC	tgT	2	2	AY.46	0.000208
ORF8	90	C90F	tGc	tTc	2	2	AY.48	0.00093
ORF8	90	C90del	TGC	---	2	2	AY.48	0.00093
ORF8	90	C90S	Tgc	Agc	2	2	AY.6	0.000082
ORF8	90	C90C	tgC	tgT	2	2	AY.69	0.000373
ORF8	90	C90F	tGc	tTc	2	2	AY.7.1	0.000225
ORF8	90	C90S	tGc	tCc	2	2	AY.75	0.000112
ORF8	90	C90X	tgC	tgA	2	2	AY.9.2	0.000073
ORF8	90	C90Y	tGc	tAc	2	2	AY.92	0.000575
ORF8	90	C90C	tgC	tgT	2	2	B	0.000256
ORF8	90	C90N	TGC	AAT	2	2	B.1	0.000018
ORF8	90	C90del	TGC	---	2	2	B.1	0.000018
ORF8	90	C90L	tGC	tTA	2	2	B.1	0.000018
ORF8	90	C90K	TGC	AAA	2	2	B.1	0.000018
ORF8	90	C90R	TgC	CgG	1	2	B.1	0.000009
ORF8	90	C90R	Tgc	Cgc	1	2	B.1	0.000009
ORF8	90	C90del	TGC	---	2	2	B.1.1.214	0.000111
ORF8	90	C90C	tgC	tgT	2	2	B.1.1.214	0.000111
ORF8	90	C90F	tGc	tTc	2	2	B.1.1.217	0.007273
ORF8	90	C90del2	TGc	--c	2	2	B.1.1.7	0.000002
ORF8	90	C90A	TGC	GCT	1	2	B.1.1.7	0.000001
ORF8	90	C90A	TGC	GCA	1	2	B.1.1.7	0.000001
ORF8	90	C90Y	tGc	tAc	2	2	B.1.160	0.000062
ORF8	90	C90Y	tGc	tAc	2	2	B.1.160.8	0.002577
ORF8	90	C90F	tGc	tTc	2	2	B.1.177	0.000026
ORF8	90	C90del	TGC	---	2	2	B.1.177	0.000026
ORF8	90	C90X	tgC	tgA	1	2	B.1.2	0.000009
ORF8	90	C90X	tGC	tAA	1	2	B.1.2	0.000009
ORF8	90	C90del	TGC	---	2	2	B.1.36	0.000292
ORF8	90	C90C	tgC	tgT	2	2	B.1.36.17	0.000988
ORF8	90	C90F	tGc	tTc	2	2	B.1.429	0.000047
ORF8	90	C90C	tgC	tgT	2	2	B.1.575	0.000607
ORF8	90	C90X	tgC	tgA	2	2	B.1.576	0.001813
ORF8	90	C90I	TGC	ATA	1	2	B.1.576	0.000907
ORF8	90	C90I	TGC	ATT	1	2	B.1.576	0.000907
ORF8	90	C90del1	tgC	tg-	2	2	B.1.617.2	0.000008
ORF8	90	C90F	tGc	tTc	2	2	B.1.626	0.011429
ORF8	90	C90del	TGC	---	2	2	B.40	0.000729
ORF8	90	C90N	TGc	AAc	1	2	P.1	0.000016
ORF8	90	C90I	TGC	ATT	1	2	P.1	0.000016
ORF8	90	C90N	TGC	AAT	1	2	P.1	0.000016
ORF8	90	C90I	TGc	ATc	1	2	P.1	0.000016
ORF8	90	C90Y	tGc	tAc	1	2	P.1	0.000016
ORF8	90	C90Y	tGC	tAT	1	2	P.1	0.000016
ORF8	90	C90F	tGc	tTc	2	2	Q.1	0.000253
ORF8	90	C90C	tgC	tgT	2	2	Q.4	0.00091
ORF8	90	C90F	tGc	tTc	2	2	Q.8	0.00033
ORF8	90	C90C	tgC	tgT	1	1	A	0.000387
ORF8	90	C90C	tgC	tgT	1	1	A.1	0.000282
ORF8	90	C90C	tgC	tgT	1	1	A.2.5	0.000499
ORF8	90	C90C	tgC	tgT	1	1	A.2.5.2	0.001572
ORF8	90	C90C	tgC	tgT	1	1	AD.2	0.000219
ORF8	90	C90del	TGC	---	1	1	AE.4	0.043478
ORF8	90	C90M	TGC	ATG	1	1	All	0
ORF8	90	C90X	tgC	tgA	1	1	AU.3	0.00211
ORF8	90	C90del1	tgC	tg-	1	1	AY.102	0.000027
ORF8	90	C90X	tgC	tgA	1	1	AY.102	0.000027
ORF8	90	C90G	Tgc	Ggc	1	1	AY.102	0.000027
ORF8	90	C90del2	tGC	t--	1	1	AY.102	0.000027
ORF8	90	C90S	TgC	AgT	1	1	AY.103	0.000006
ORF8	90	C90R	Tgc	Cgc	1	1	AY.103	0.000006
ORF8	90	C90F	tGc	tTc	1	1	AY.106	0.000335
ORF8	90	C90Y	tGc	tAc	1	1	AY.106	0.000335
ORF8	90	C90del	TGC	---	1	1	AY.108	0.001103
ORF8	90	C90C	tgC	tgT	1	1	AY.108	0.001103
ORF8	90	C90C	tgC	tgT	1	1	AY.111	0.000183
ORF8	90	C90Y	tGc	tAc	1	1	AY.114	0.000231
ORF8	90	C90F	tGc	tTc	1	1	AY.116	0.000287
ORF8	90	C90del	TGC	---	1	1	AY.116.1	0.000311
ORF8	90	C90del	TGC	---	1	1	AY.118	0.000063
ORF8	90	C90F	tGc	tTc	1	1	AY.119	0.000035
ORF8	90	C90Y	tGc	tAc	1	1	AY.120	0.000037
ORF8	90	C90F	tGc	tTc	1	1	AY.120	0.000037
ORF8	90	C90C	tgC	tgT	1	1	AY.120	0.000037
ORF8	90	C90F	tGc	tTc	1	1	AY.121	0.000135
ORF8	90	C90F	tGc	tTc	1	1	AY.14	0.000088
ORF8	90	C90del	TGC	---	1	1	AY.16.1	0.00047
ORF8	90	C90C	tgC	tgT	1	1	AY.16.1	0.00047
ORF8	90	C90del	TGC	---	1	1	AY.19	0.00114
ORF8	90	C90S	Tgc	Agc	1	1	AY.20	0.000039
ORF8	90	C90F	tGc	tTc	1	1	AY.24	0.000431
ORF8	90	C90K	TGC	AAA	1	1	AY.25	0.000006
ORF8	90	C90L	tGC	tTA	1	1	AY.25	0.000006
ORF8	90	C90X	tGC	tAA	1	1	AY.25	0.000006
ORF8	90	C90N	TGC	AAT	1	1	AY.25	0.000006
ORF8	90	C90del	TGC	---	1	1	AY.27	0.000065
ORF8	90	C90F	tGc	tTc	1	1	AY.29	0.000016
ORF8	90	C90X	tgC	tgA	1	1	AY.29	0.000016
ORF8	90	C90Y	tGc	tAc	1	1	AY.3	0.00001
ORF8	90	C90C	tgC	tgT	1	1	AY.3	0.00001
ORF8	90	C90C	tgC	tgT	1	1	AY.3.1	0.000085
ORF8	90	C90C	tgC	tgT	1	1	AY.30	0.000396
ORF8	90	C90F	tGc	tTc	1	1	AY.33	0.000067
ORF8	90	C90F	tGc	tTc	1	1	AY.34	0.000097
ORF8	90	C90C	tgC	tgT	1	1	AY.34	0.000097
ORF8	90	C90R	Tgc	Cgc	1	1	AY.34.1	0.00051
ORF8	90	C90C	tgC	tgT	1	1	AY.35	0.000233
ORF8	90	C90del	TGC	---	1	1	AY.39	0.000025
ORF8	90	C90C	tgC	tgT	1	1	AY.39	0.000025
ORF8	90	C90C	tgC	tgT	1	1	AY.39.2	0.001541
ORF8	90	C90S	Tgc	Agc	1	1	AY.4	0.000002
ORF8	90	C90del	TGC	---	1	1	AY.4.2	0.000022
ORF8	90	C90C	tgC	tgT	1	1	AY.4.5	0.000107
ORF8	90	C90Y	tGc	tAc	1	1	AY.4.5	0.000107
ORF8	90	C90Y	tGc	tAc	1	1	AY.42	0.00004
ORF8	90	C90F	tGc	tTc	1	1	AY.42	0.00004
ORF8	90	C90G	Tgc	Ggc	1	1	AY.43	0.000004
ORF8	90	C90W	tgC	tgG	1	1	AY.44	0.000006
ORF8	90	C90R	Tgc	Cgc	1	1	AY.44	0.000006
ORF8	90	C90X	tgC	tgA	1	1	AY.44	0.000006
ORF8	90	C90F	tGc	tTc	1	1	AY.46.6	0.000072
ORF8	90	C90Y	tGc	tAc	1	1	AY.5	0.000021
ORF8	90	C90del	TGC	---	1	1	AY.5	0.000021
ORF8	90	C90Y	tGc	tAc	1	1	AY.5.3	0.000337
ORF8	90	C90X	tgC	tgA	1	1	AY.54	0.000095
ORF8	90	C90C	tgC	tgT	1	1	AY.55	0.000917
ORF8	90	C90Y	tGc	tAc	1	1	AY.58	0.000907
ORF8	90	C90del	TGC	---	1	1	AY.58	0.000907
ORF8	90	C90F	tGc	tTc	1	1	AY.59	0.00053
ORF8	90	C90Y	tGc	tAc	1	1	AY.6	0.000041
ORF8	90	C90F	tGc	tTc	1	1	AY.61	0.000105
ORF8	90	C90G	Tgc	Ggc	1	1	AY.65	0.000533
ORF8	90	C90F	tGc	tTc	1	1	AY.68	0.000274
ORF8	90	C90X	tgC	tgA	1	1	AY.69	0.000187
ORF8	90	C90C	tgC	tgT	1	1	AY.71	0.000475
ORF8	90	C90F	tGc	tTc	1	1	AY.77	0.001127
ORF8	90	C90R	Tgc	Cgc	1	1	AY.82	0.001357
ORF8	90	C90X	tgC	tgA	1	1	AY.93	0.000273
ORF8	90	C90C	tgC	tgT	1	1	AY.94	0.000443
ORF8	90	C90Y	tGc	tAc	1	1	AY.98.1	0.000048
ORF8	90	C90F	tGc	tTc	1	1	AY.98.1	0.000048
ORF8	90	C90Y	tGc	tAc	1	1	AY.99	0.001049
ORF8	90	C90F	tGc	tTc	1	1	B	0.000128
ORF8	90	C90del1	tgC	tg-	1	1	B.1	0.000009
ORF8	90	C90W	tgC	tgG	1	1	B.1	0.000009
ORF8	90	C90N	TGC	AAT	1	1	B.1.1	0.000018
ORF8	90	C90G	TgC	GgT	1	1	B.1.1	0.000018
ORF8	90	C90R	TgC	AgA	1	1	B.1.1	0.000018
ORF8	90	C90S	TgC	AgT	1	1	B.1.1	0.000018
ORF8	90	C90K	TGC	AAA	1	1	B.1.1	0.000018
ORF8	90	C90Y	tGC	tAT	1	1	B.1.1	0.000018
ORF8	90	C90R	Tgc	Cgc	1	1	B.1.1.1	0.000327
ORF8	90	C90C	tgC	tgT	1	1	B.1.1.101	0.01
ORF8	90	C90C	tgC	tgT	1	1	B.1.1.170	0.001247
ORF8	90	C90del	TGC	---	1	1	B.1.1.174	0.003378
ORF8	90	C90C	tgC	tgT	1	1	B.1.1.205	0.003717
ORF8	90	C90del	TGC	---	1	1	B.1.1.216	0.00089
ORF8	90	C90C	tgC	tgT	1	1	B.1.1.222	0.000204
ORF8	90	C90del	TGC	---	1	1	B.1.1.236	0.006897
ORF8	90	C90del	TGC	---	1	1	B.1.1.28	0.000311
ORF8	90	C90del2	TGc	--c	1	1	B.1.1.284	0.000107
ORF8	90	C90H	TGc	CAc	1	1	B.1.1.315	0.008475
ORF8	90	C90C	tgC	tgT	1	1	B.1.1.316	0.000925
ORF8	90	C90X	tgC	tgA	1	1	B.1.1.318	0.000302
ORF8	90	C90C	tgC	tgT	1	1	B.1.1.348	0.000796
ORF8	90	C90F	tGc	tTc	1	1	B.1.1.354	0.004386
ORF8	90	C90del	TGC	---	1	1	B.1.1.354	0.004386
ORF8	90	C90del	TGC	---	1	1	B.1.1.37	0.000193
ORF8	90	C90F	tGc	tTc	1	1	B.1.1.519	0.00004
ORF8	90	C90S	tGc	tCc	1	1	B.1.1.519	0.00004
ORF8	90	C90M	TGC	ATG	1	1	B.1.1.7	0.000001
ORF8	90	C90C	tgC	tgT	1	1	B.1.1.70	0.000341
ORF8	90	C90del	TGC	---	1	1	B.1.126	0.001276
ORF8	90	C90F	tGc	tTc	1	1	B.1.160	0.000031
ORF8	90	C90C	tgC	tgT	1	1	B.1.160.20	0.008929
ORF8	90	C90F	tGc	tTc	1	1	B.1.167	0.007812
ORF8	90	C90del1	tgC	tg-	1	1	B.1.177	0.000013
ORF8	90	C90del	TGC	---	1	1	B.1.177.12	0.000152
ORF8	90	C90C	tgC	tgT	1	1	B.1.177.12	0.000152
ORF8	90	C90F	tGc	tTc	1	1	B.1.177.4	0.000211
ORF8	90	C90C	tgC	tgT	1	1	B.1.177.54	0.000606
ORF8	90	C90S	tGc	tCc	1	1	B.1.177.63	0.002703
ORF8	90	C90C	tgC	tgT	1	1	B.1.177.7	0.000165
ORF8	90	C90del	TGC	---	1	1	B.1.177.7	0.000165
ORF8	90	C90C	tgC	tgT	1	1	B.1.177.8	0.000752
ORF8	90	C90C	tgC	tgT	1	1	B.1.177.81	0.000189
ORF8	90	C90del	TGC	---	1	1	B.1.177.83	0.001481
ORF8	90	C90del	TGC	---	1	1	B.1.195	0.005025
ORF8	90	C90G	Tgc	Ggc	1	1	B.1.2	0.000009
ORF8	90	C90S	tGc	tCc	1	1	B.1.2	0.000009
ORF8	90	C90del	TGC	---	1	1	B.1.210	0.002132
ORF8	90	C90X	tgC	tgA	1	1	B.1.232	0.000537
ORF8	90	C90C	tgC	tgT	1	1	B.1.243	0.00007
ORF8	90	C90F	tGc	tTc	1	1	B.1.243	0.00007
ORF8	90	C90F	tGc	tTc	1	1	B.1.258	0.000067
ORF8	90	C90C	tgC	tgT	1	1	B.1.258	0.000067
ORF8	90	C90del	TGC	---	1	1	B.1.258.12	0.007874
ORF8	90	C90del	TGC	---	1	1	B.1.258.17	0.000104
ORF8	90	C90del	TGC	---	1	1	B.1.351	0.00003
ORF8	90	C90del	TGC	---	1	1	B.1.351.2	0.000303
ORF8	90	C90R	Tgc	Cgc	1	1	B.1.36.19	0.009259
ORF8	90	C90F	tGc	tTc	1	1	B.1.36.29	0.000517
ORF8	90	C90F	tGc	tTc	1	1	B.1.36.38	0.001642
ORF8	90	C90F	tGc	tTc	1	1	B.1.375	0.00082
ORF8	90	C90C	tgC	tgT	1	1	B.1.400	0.000429
ORF8	90	C90del1	tgC	tg-	1	1	B.1.427	0.00005
ORF8	90	C90Y	tGc	tAc	1	1	B.1.427	0.00005
ORF8	90	C90F	tGc	tTc	1	1	B.1.427	0.00005
ORF8	90	C90F	tGc	tTc	1	1	B.1.428	0.00102
ORF8	90	C90C	tgC	tgT	1	1	B.1.428.2	0.033333
ORF8	90	C90del	TGC	---	1	1	B.1.466.2	0.000391
ORF8	90	C90del	TGC	---	1	1	B.1.468	0.005714
ORF8	90	C90C	tgC	tgT	1	1	B.1.523	0.002451
ORF8	90	C90C	tgC	tgT	1	1	B.1.526	0.000024
ORF8	90	C90del	TGC	---	1	1	B.1.540	0.009709
ORF8	90	C90F	tGc	tTc	1	1	B.1.561	0.000397
ORF8	90	C90F	tGc	tTc	1	1	B.1.564	0.000426
ORF8	90	C90F	tGc	tTc	1	1	B.1.571	0.009709
ORF8	90	C90F	tGC	tTT	1	1	B.1.574	0.002151
ORF8	90	C90C	tgC	tgT	1	1	B.1.576	0.000907
ORF8	90	C90R	TgC	AgA	1	1	B.1.576	0.000907
ORF8	90	C90L	tGC	tTA	1	1	B.1.576	0.000907
ORF8	90	C90S	TgC	AgT	1	1	B.1.576	0.000907
ORF8	90	C90F	tGC	tTT	1	1	B.1.576	0.000907
ORF8	90	C90C	tgC	tgT	1	1	B.1.582	0.000491
ORF8	90	C90del	TGC	---	1	1	B.1.596	0.000087
ORF8	90	C90del	TGC	---	1	1	B.1.597	0.00463
ORF8	90	C90del2	TGC	--N	1	1	B.1.617.2	0.000004
ORF8	90	C90S	tGc	tCc	1	1	B.1.617.2	0.000004
ORF8	90	C90C	tgC	tgT	1	1	B.1.619.1	0.000641
ORF8	90	C90F	tGc	tTc	1	1	B.1.619.1	0.000641
ORF8	90	C90Y	tGc	tAc	1	1	B.1.621	0.000089
ORF8	90	C90del	TGC	---	1	1	B.1.621	0.000089
ORF8	90	C90C	tgC	tgT	1	1	B.1.621	0.000089
ORF8	90	C90F	tGc	tTc	1	1	B.1.621.1	0.000506
ORF8	90	C90F	tGc	tTc	1	1	B.1.628	0.000352
ORF8	90	C90F	tGc	tTc	1	1	B.1.637	0.000073
ORF8	90	C90S	Tgc	Agc	1	1	B.1.637	0.000073
ORF8	90	C90C	tgC	tgT	1	1	B.40	0.000364
ORF8	90	C90Y	tGc	tAc	1	1	B.55	0.00295
ORF8	90	C90C	tgC	tgT	1	1	B.6.6	0.000889
ORF8	90	C90C	tgC	tgT	1	1	C.1.2	0.004255
ORF8	90	C90del	TGC	---	1	1	C.26	0.007353
ORF8	90	C90C	tgC	tgT	1	1	C.26	0.007353
ORF8	90	C90del	TGC	---	1	1	C.36	0.000911
ORF8	90	C90C	tgC	tgT	1	1	C.36.3	0.000567
ORF8	90	C90C	tgC	tgT	1	1	C.37	0.000116
ORF8	90	C90S	tGc	tCc	1	1	D.2	0.000075
ORF8	90	C90Y	tGc	tAc	1	1	D.2	0.000075
ORF8	90	C90C	tgC	tgT	1	1	L.3	0.003546
ORF8	90	C90del	TGC	---	1	1	M.3	0.076923
ORF8	90	C90del	TGC	---	1	1	N.6	0.007092
ORF8	90	C90del2	TGc	--c	1	1	P.1	0.000016
ORF8	90	C90del	TGC	---	1	1	P.1.12	0.000484
ORF8	90	C90del2	TGc	--c	1	1	P.1.15	0.000232
ORF8	90	C90del	TGC	---	1	1	P.1.15	0.000232
ORF8	90	C90C	tgC	tgT	1	1	P.1.15	0.000232
ORF8	90	C90del2	TGc	--c	1	1	P.1.8	0.004785
ORF8	90	C90C	tgC	tgT	1	1	P.2	0.000187
ORF8	90	C90F	tGc	tTc	1	1	P.2	0.000187
ORF8	90	C90del	TGC	---	1	1	P.6	0.003145
ORF8	90	C90C	tgC	tgT	1	1	Q.1	0.000126
ORF8	90	C90C	tgC	tgT	1	1	Q.3	0.000145
ORF8	90	C90R	Tgc	Cgc	1	1	Q.8	0.000165
ORF8	90	C90del	TGC	---	1	1	R.1	0.00009

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.