CoV-GLUE Mutation

CoV-GLUE Mutation: ORF = ORF8 : CodonNum = 59 & Codon = gGa

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORF	CodonNum	Mut	ORF1abMut	MutType	RefCodon	MutCodon	AACount	CodonCount	CodonProp	Genome Position
ORF8	59	E59G		nonsyn	gAa	gGa	195	172	0.882051	28068-28070

Details of the mutation no within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORF	CodonNum	Mut	RefCodon	MutCodon	CodonCount	AACount	Lineage	LineageCodonProp
ORF8	59	E59G	gAa	gGa	172	195	All	0.000033
ORF8	59	E59G	gAa	gGa	77	80	B.1.1.7	0.000069
ORF8	59	E59G	gAa	gGa	13	13	B.1.617.2	0.000049
ORF8	59	E59G	gAa	gGa	11	11	B.1	0.000101
ORF8	59	E59G	gAa	gGa	10	10	AY.23	0.000697
ORF8	59	E59G	gAa	gGa	10	10	B.1.1	0.000181
ORF8	59	E59G	gAa	gGa	8	8	AY.120	0.000297
ORF8	59	E59G	gAa	gGa	6	6	AY.4	0.000009
ORF8	59	E59G	gAa	gGa	2	5	P.1	0.000032
ORF8	59	E59G	gAa	gGa	4	4	AY.3	0.00004
ORF8	59	E59G	gAa	gGa	3	4	AY.43	0.000013
ORF8	59	E59G	gAa	gGa	3	3	AY.39	0.000074
ORF8	59	E59G	gAa	gGa	3	3	AY.61	0.000314
ORF8	59	E59G	gAa	gGa	3	3	B.1.526	0.000071
ORF8	59	E59G	gAa	gGa	2	2	A	0.000774
ORF8	59	E59G	gAa	gGa	2	2	AY.1	0.000791
ORF8	59	E59G	gAa	gGa	2	2	AY.13	0.000322
ORF8	59	E59G	gAa	gGa	2	2	AY.26	0.000057
ORF8	59	E59G	gAa	gGa	2	2	AY.29	0.000032
ORF8	59	E59G	gAa	gGa	2	2	AY.6	0.000082
ORF8	59	E59G	gAa	gGa	1	1	AY.33	0.000067
ORF8	59	E59G	gAa	gGa	1	1	AY.68	0.000274
ORF8	59	E59G	gAa	gGa	1	1	B.1.1.409	0.002833
ORF8	59	E59G	gAa	gGa	1	1	B.1.366	0.004878
ORF8	59	E59G	gAa	gGa	1	1	B.1.466.2	0.000391
ORF8	59	E59G	gAa	gGa	1	1	P.1.17	0.000162
ORF8	59	E59G	gAa	gGa	1	1	Q.8	0.000165

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.