CoV-GLUE Mutation

CoV-GLUE Mutation: ORF = ORF8 : CodonNum = 3 & Codon = Ctt

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORF	CodonNum	Mut	ORF1abMut	MutType	RefCodon	MutCodon	AACount	CodonCount	CodonProp	Genome Position
ORF8	3	F3L		nonsyn	Ttt	Ctt	3132	3089	0.986271	27900-27902

Details of the mutation no within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORF	CodonNum	Mut	RefCodon	MutCodon	CodonCount	AACount	Lineage	LineageCodonProp
ORF8	3	F3L	Ttt	Ctt	3089	3132	All	0.000591
ORF8	3	F3L	Ttt	Ctt	1301	1319	AY.4	0.002025
ORF8	3	F3L	Ttt	Ctt	583	583	B.1.1.433	0.830484
ORF8	3	F3L	Ttt	Ctt	265	268	B.1.1.7	0.000237
ORF8	3	F3L	Ttt	Ctt	148	149	B.1.160	0.004616
ORF8	3	F3L	Ttt	Ctt	79	79	AY.4.2	0.001713
ORF8	3	F3L	Ttt	Ctt	79	79	AY.46.6	0.005704
ORF8	3	F3L	Ttt	Ctt	50	51	AY.25	0.000301
ORF8	3	F3L	Ttt	Ctt	51	51	AY.44	0.00031
ORF8	3	F3L	Ttt	Ctt	36	37	B.1.617.2	0.000136
ORF8	3	F3L	Ttt	Ctt	35	35	AY.103	0.000217
ORF8	3	F3L	Ttt	Ctt	33	33	AY.39.1	0.001307
ORF8	3	F3L	Ttt	Ctt	29	29	B.1.118	0.194631
ORF8	3	F3L	Ttt	Ctt	24	24	AY.102	0.000636
ORF8	3	F3L	Ttt	Ctt	22	22	B.1.637	0.001608
ORF8	3	F3L	Ttt	Ctt	21	21	AY.3	0.000209
ORF8	3	F3L	Ttt	Ctt	19	19	AY.120	0.000706
ORF8	3	F3L	Ttt	Ctt	16	17	B.1	0.000147
ORF8	3	F3L	Ttt	Ctt	16	16	B.1.1.222	0.003264
ORF8	3	F3L	Ttt	Ctt	16	16	C.29	1
ORF8	3	F3L	Ttt	Ctt	14	14	AY.43	0.000062
ORF8	3	F3L	Ttt	Ctt	13	13	AY.100	0.000598
ORF8	3	F3L	Ttt	Ctt	2	12		0.111111
ORF8	3	F3L	Ttt	Ctt	12	12	AY.117	0.001014
ORF8	3	F3L	Ttt	Ctt	12	12	B.1.1	0.000218
ORF8	3	F3L	Ttt	Ctt	10	11	AY.29	0.000158
ORF8	3	F3L	Ttt	Ctt	8	9	B.1.2	0.00007
ORF8	3	F3L	Ttt	Ctt	8	9	P.1	0.000126
ORF8	3	F3L	Ttt	Ctt	8	8	AY.39	0.000198
ORF8	3	F3L	Ttt	Ctt	8	8	AY.5.4	0.002214
ORF8	3	F3L	Ttt	Ctt	5	7	AY.26	0.000142
ORF8	3	F3L	Ttt	Ctt	7	7	B.1.177.46	0.006428
ORF8	3	F3L	Ttt	Ctt	7	7	B.1.351	0.000208
ORF8	3	F3L	Ttt	Ctt	7	7	P.1.14	0.000335
ORF8	3	F3L	Ttt	Ctt	6	6	AY.14	0.000528
ORF8	3	F3L	Ttt	Ctt	6	6	AY.20	0.000233
ORF8	3	F3L	Ttt	Ctt	5	6	AY.9.2	0.000184
ORF8	3	F3L	Ttt	Ctt	5	5	B.1.1.176	0.002197
ORF8	3	F3L	Ttt	Ctt	5	5	B.1.1.294	0.006329
ORF8	3	F3L	Ttt	Ctt	5	5	B.1.1.33	0.002104
ORF8	3	F3L	Ttt	Ctt	4	4	AY.33	0.000267
ORF8	3	F3L	Ttt	Ctt	4	4	B.1.177	0.000053
ORF8	3	F3L	Ttt	Ctt	4	4	B.1.612	0.01061
ORF8	3	F3L	Ttt	Ctt	3	3	AY.119	0.000106
ORF8	3	F3L	Ttt	Ctt	3	3	AY.23	0.000209
ORF8	3	F3L	Ttt	Ctt	3	3	AY.3.1	0.000256
ORF8	3	F3L	Ttt	Ctt	3	3	AY.46.4	0.000494
ORF8	3	F3L	Ttt	Ctt	3	3	B.1.1.519	0.000119
ORF8	3	F3L	Ttt	Ctt	3	3	B.1.177.12	0.000455
ORF8	3	F3L	Ttt	Ctt	3	3	B.1.236	0.00616
ORF8	3	F3L	Ttt	Ctt	3	3	B.1.588	0.00273
ORF8	3	F3L	Ttt	Ctt	3	3	B.1.596	0.000261
ORF8	3	F3L	Ttt	Ctt	3	3	Q.2	0.00184
ORF8	3	F3L	Ttt	Ctt	2	2	AY.4.5	0.000215
ORF8	3	F3L	Ttt	Ctt	2	2	AY.42	0.00008
ORF8	3	F3L	Ttt	Ctt	2	2	AY.71	0.00095
ORF8	3	F3L	Ttt	Ctt	2	2	AY.9	0.000135
ORF8	3	F3L	Ttt	Ctt	2	2	AY.92	0.000575
ORF8	3	F3L	Ttt	Ctt	2	2	AY.99.2	0.000184
ORF8	3	F3L	Ttt	Ctt	2	2	B.1.177.33	0.003289
ORF8	3	F3L	Ttt	Ctt	2	2	B.1.433	0.00639
ORF8	3	F3L	Ttt	Ctt	2	2	B.1.621	0.000177
ORF8	3	F3L	Ttt	Ctt	2	2	B.12	0.012821
ORF8	3	F3L	Ttt	Ctt	2	2	C.37	0.000232
ORF8	3	F3L	Ttt	Ctt	1	1	A.2.5	0.000499
ORF8	3	F3L	Ttt	Ctt	1	1	AM.4	0.003571
ORF8	3	F3L	Ttt	Ctt	1	1	AY.110	0.000113
ORF8	3	F3L	Ttt	Ctt	1	1	AY.116	0.000287
ORF8	3	F3L	Ttt	Ctt	1	1	AY.118	0.000063
ORF8	3	F3L	Ttt	Ctt	1	1	AY.12	0.000316
ORF8	3	F3L	Ttt	Ctt	1	1	AY.34	0.000097
ORF8	3	F3L	Ttt	Ctt	1	1	AY.45	0.000122
ORF8	3	F3L	Ttt	Ctt	1	1	AY.47	0.000031
ORF8	3	F3L	Ttt	Ctt	1	1	AY.5	0.000021
ORF8	3	F3L	Ttt	Ctt	1	1	AY.57	0.000656
ORF8	3	F3L	Ttt	Ctt	1	1	AY.6	0.000041
ORF8	3	F3L	Ttt	Ctt	1	1	AY.60	0.000938
ORF8	3	F3L	Ttt	Ctt	1	1	AY.61	0.000105
ORF8	3	F3L	Ttt	Ctt	1	1	AY.64	0.000595
ORF8	3	F3L	Ttt	Ctt	1	1	AY.7.1	0.000113
ORF8	3	F3L	Ttt	Ctt	1	1	AY.74	0.000116
ORF8	3	F3L	Ttt	Ctt	1	1	AY.87	0.000833
ORF8	3	F3L	Ttt	Ctt	1	1	AY.98	0.000079
ORF8	3	F3L	Ttt	Ctt	1	1	B.1.1.291	0.000742
ORF8	3	F3L	Ttt	Ctt	1	1	B.1.1.434	0.000349
ORF8	3	F3L	Ttt	Ctt	1	1	B.1.1.45	0.014085
ORF8	3	F3L	Ttt	Ctt	1	1	B.1.1.67	0.004566
ORF8	3	F3L	Ttt	Ctt	1	1	B.1.1.89	0.006061
ORF8	3	F3L	Ttt	Ctt	1	1	B.1.177.23	0.003236
ORF8	3	F3L	Ttt	Ctt	1	1	B.1.177.73	0.000566
ORF8	3	F3L	Ttt	Ctt	1	1	B.1.214.2	0.0006
ORF8	3	F3L	Ttt	Ctt	1	1	B.1.234	0.000132
ORF8	3	F3L	Ttt	Ctt	1	1	B.1.239	0.001221
ORF8	3	F3L	Ttt	Ctt	1	1	B.1.243	0.00007
ORF8	3	F3L	Ttt	Ctt	1	1	B.1.258	0.000067
ORF8	3	F3L	Ttt	Ctt	1	1	B.1.380	0.006623
ORF8	3	F3L	Ttt	Ctt	1	1	B.1.399	0.001934
ORF8	3	F3L	Ttt	Ctt	1	1	B.1.427	0.00005
ORF8	3	F3L	Ttt	Ctt	1	1	B.1.429	0.000024
ORF8	3	F3L	Ttt	Ctt	1	1	B.1.459	0.004082
ORF8	3	F3L	Ttt	Ctt	1	1	B.1.470	0.001404
ORF8	3	F3L	Ttt	Ctt	1	1	B.1.525	0.000113
ORF8	3	F3L	Ttt	Ctt	1	1	B.1.526	0.000024
ORF8	3	F3L	Ttt	Ctt	1	1	B.1.540	0.009709
ORF8	3	F3L	Ttt	Ctt	1	1	B.1.574	0.002151
ORF8	3	F3L	Ttt	Ctt	1	1	B.1.577	0.000687
ORF8	3	F3L	Ttt	Ctt	1	1	B.1.580	0.004065
ORF8	3	F3L	Ttt	Ctt	1	1	B.1.595	0.000261
ORF8	3	F3L	Ttt	Ctt	1	1	B.1.617.1	0.000129
ORF8	3	F3L	Ttt	Ctt	1	1	B.1.621.1	0.000506
ORF8	3	F3L	Ttt	Ctt	1	1	D.3	0.005917
ORF8	3	F3L	Ttt	Ctt	1	1	P.1.15	0.000232
ORF8	3	F3L	Ttt	Ctt	1	1	Q.7	0.001111

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.