CoV-GLUE Mutation

CoV-GLUE Mutation: ORF = ORF8 : CodonNum = 27 & Codon = cTa

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORF	CodonNum	Mut	ORF1abMut	MutType	RefCodon	MutCodon	AACount	CodonCount	CodonProp	Genome Position
ORF8	27	Q27L		nonsyn	cAa	cTa	152	147	0.967105	27972-27974

Details of the mutation no within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORF	CodonNum	Mut	RefCodon	MutCodon	CodonCount	AACount	Lineage	LineageCodonProp
ORF8	27	Q27L	cAa	cTa	147	152	All	0.000028
ORF8	27	Q27L	cAa	cTa	36	36	AY.3	0.000358
ORF8	27	Q27L	cAa	cTa	25	25	AY.103	0.000155
ORF8	27	Q27L	cAa	cTa	14	14	P.1	0.000221
ORF8	27	Q27L	cAa	cTa	12	12	AY.25	0.000072
ORF8	27	Q27L	cAa	cTa	12	12	AY.4	0.000019
ORF8	27	Q27L	cAa	cTa	8	8	B.1	0.000073
ORF8	27	Q27L	cAa	cTa	2	7		0.111111
ORF8	27	Q27L	cAa	cTa	4	4	AY.102	0.000106
ORF8	27	Q27L	cAa	cTa	4	4	AY.47	0.000124
ORF8	27	Q27L	cAa	cTa	4	4	B.1.617.2	0.000015
ORF8	27	Q27L	cAa	cTa	3	3	AY.20	0.000117
ORF8	27	Q27L	cAa	cTa	3	3	B.1.2	0.000026
ORF8	27	Q27L	cAa	cTa	2	2	AY.43	0.000009
ORF8	27	Q27L	cAa	cTa	1	1	AY.119	0.000035
ORF8	27	Q27L	cAa	cTa	1	1	AY.14	0.000088
ORF8	27	Q27L	cAa	cTa	1	1	AY.27	0.000065
ORF8	27	Q27L	cAa	cTa	1	1	AY.33	0.000067
ORF8	27	Q27L	cAa	cTa	1	1	AY.44	0.000006
ORF8	27	Q27L	cAa	cTa	1	1	AY.75	0.000056
ORF8	27	Q27L	cAa	cTa	1	1	AY.9.1	0.000084
ORF8	27	Q27L	cAa	cTa	1	1	B.1.1.519	0.00004
ORF8	27	Q27L	cAa	cTa	1	1	B.1.1.7	0.000001
ORF8	27	Q27L	cAa	cTa	1	1	B.1.206	0.000816
ORF8	27	Q27L	cAa	cTa	1	1	B.1.243	0.00007
ORF8	27	Q27L	cAa	cTa	1	1	B.1.351	0.00003
ORF8	27	Q27L	cAa	cTa	1	1	B.1.421	0.007463
ORF8	27	Q27L	cAa	cTa	1	1	B.1.561	0.000397
ORF8	27	Q27L	cAa	cTa	1	1	B.1.617.1	0.000129
ORF8	27	Q27L	cAa	cTa	1	1	B.1.621	0.000089
ORF8	27	Q27L	cAa	cTa	1	1	B.1.627	0.00202
ORF8	27	Q27L	cAa	cTa	1	1	P.1.10	0.000269

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.