CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF7b : Mut = L25F

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF7b25L25FnonsynCttTtt146514510.99044427828-27830
ORF7b25L25FnonsynCtTTtC1465140.0095563127828-27830

Details of the mutation L25F within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF7b25L25FCttTtt14511465All0.000278
ORF7b25L25FCtTTtC141465All0.000003
ORF7b25L25FCttTtt487487B.1.1.70.000436
ORF7b25L25FCttTtt102102B.1.4290.0024
ORF7b25L25FCttTtt7979AY.40.000123
ORF7b25L25FCttTtt7575B.1.1770.000988
ORF7b25L25FCttTtt6868B.1.20.000599
ORF7b25L25FCttTtt5959B.1.617.20.000222
ORF7b25L25FCttTtt3439B.10.000311
ORF7b25L25FCtTTtC539B.10.000046
ORF7b25L25FCttTtt3636B.1.5250.004074
ORF7b25L25FCttTtt2828B.1.1.1010.28
ORF7b25L25FCttTtt2627B.1.10.000472
ORF7b25L25FCtTTtC127B.1.10.000018
ORF7b25L25FCttTtt2424B.1.1.4450.888889
ORF7b25L25FCttTtt2121P.1.150.004879
ORF7b25L25FCttTtt1919AY.430.000084
ORF7b25L25FCttTtt1919AY.98.10.00092
ORF7b25L25FCttTtt1717AY.440.000103
ORF7b25L25FCttTtt1616A.270.02649
ORF7b25L25FCttTtt1415AY.390.000346
ORF7b25L25FCtTTtC115AY.390.000025
ORF7b25L25FCttTtt1313AY.260.000368
ORF7b25L25FCttTtt1313AY.29.10.002867
ORF7b25L25FCttTtt1313AY.30.000129
ORF7b25L25FCttTtt1212AY.1030.000075
ORF7b25L25FCttTtt1212P.10.000189
ORF7b25L25FCttTtt1111B.1.1600.000343
ORF7b25L25FCttTtt1010B.1.6370.000731
ORF7b25L25FCttTtt99AY.420.000362
ORF7b25L25FCttTtt88AY.1200.000297
ORF7b25L25FCttTtt88B.1.3510.000238
ORF7b25L25FCttTtt88B.1.5950.002088
ORF7b25L25FCttTtt77AY.200.000272
ORF7b25L25FCttTtt66AY.1000.000276
ORF7b25L25FCttTtt66AY.1020.000159
ORF7b25L25FCttTtt66AY.3.10.000512
ORF7b25L25FCttTtt66AY.540.000572
ORF7b25L25FCttTtt66B.1.2650.007624
ORF7b25L25FCttTtt56P.1.10.001588
ORF7b25L25FCtTTtC16P.1.10.000318
ORF7b25L25FCttTtt55AY.1180.000313
ORF7b25L25FCttTtt55AY.1190.000177
ORF7b25L25FCttTtt55B.1.1.2070.00591
ORF7b25L25FCttTtt55B.1.1.5190.000199
ORF7b25L25FCttTtt55B.1.36.220.006039
ORF7b25L25FCttTtt34AY.850.001282
ORF7b25L25FCtTTtC14AY.850.000427
ORF7b25L25FCttTtt44B.1.1.2260.023256
ORF7b25L25FCttTtt44B.1.2210.000284
ORF7b25L25FCttTtt44B.1.2430.000278
ORF7b25L25FCttTtt44B.1.4690.01444
ORF7b25L25FCttTtt33AY.250.000018
ORF7b25L25FCttTtt33AY.4.20.000065
ORF7b25L25FCttTtt33AY.590.001589
ORF7b25L25FCttTtt33AY.60.000123
ORF7b25L25FCttTtt33B.1.1.330.001263
ORF7b25L25FCttTtt23B.1.1.4090.005666
ORF7b25L25FCtTTtC13B.1.1.4090.002833
ORF7b25L25FCttTtt33B.1.1700.012931
ORF7b25L25FCttTtt23B.1.177.730.001133
ORF7b25L25FCtTTtC13B.1.177.730.000566
ORF7b25L25FCttTtt33B.1.2910.057692
ORF7b25L25FCttTtt33B.1.360.000438
ORF7b25L25FCttTtt220.111111
ORF7b25L25FCttTtt22AY.1050.001286
ORF7b25L25FCttTtt22AY.140.000176
ORF7b25L25FCttTtt22AY.230.000139
ORF7b25L25FCttTtt22AY.350.000466
ORF7b25L25FCttTtt22AY.39.10.000079
ORF7b25L25FCttTtt22AY.4.2.10.000298
ORF7b25L25FCttTtt22AY.9.20.000073
ORF7b25L25FCttTtt22B.1.1.10.000653
ORF7b25L25FCttTtt22B.1.1.2220.000408
ORF7b25L25FCttTtt22B.1.1.2910.001485
ORF7b25L25FCtTTtC12B.1.1390.000733
ORF7b25L25FCttTtt12B.1.1390.000733
ORF7b25L25FCttTtt22B.1.177.320.002699
ORF7b25L25FCttTtt22B.1.177.650.001331
ORF7b25L25FCttTtt22B.1.2400.000431
ORF7b25L25FCttTtt22B.1.2580.000133
ORF7b25L25FCttTtt22B.1.438.10.000215
ORF7b25L25FCttTtt22B.1.5260.000047
ORF7b25L25FCttTtt22B.1.5960.000174
ORF7b25L25FCtTTtC12B.1.6270.00202
ORF7b25L25FCttTtt12B.1.6270.00202
ORF7b25L25FCtTTtC11AY.1080.001103
ORF7b25L25FCttTtt11AY.1130.000142
ORF7b25L25FCttTtt11AY.130.000161
ORF7b25L25FCttTtt11AY.16.10.00047
ORF7b25L25FCttTtt11AY.290.000016
ORF7b25L25FCttTtt11AY.300.000396
ORF7b25L25FCttTtt11AY.360.000148
ORF7b25L25FCttTtt11AY.460.000104
ORF7b25L25FCttTtt11AY.46.50.000198
ORF7b25L25FCttTtt11AY.470.000031
ORF7b25L25FCttTtt11AY.50.000021
ORF7b25L25FCttTtt11AY.5.40.000277
ORF7b25L25FCttTtt11AY.770.001127
ORF7b25L25FCttTtt11AY.950.000761
ORF7b25L25FCttTtt11AY.980.000079
ORF7b25L25FCttTtt11B0.000128
ORF7b25L25FCttTtt11B.1.1.1590.004673
ORF7b25L25FCttTtt11B.1.1.1630.007634
ORF7b25L25FCttTtt11B.1.1.2160.00089
ORF7b25L25FCttTtt11B.1.1.2320.001815
ORF7b25L25FCttTtt11B.1.1.280.000311
ORF7b25L25FCttTtt11B.1.1.2820.011628
ORF7b25L25FCttTtt11B.1.1.2840.000107
ORF7b25L25FCttTtt11B.1.1.3060.000438
ORF7b25L25FCttTtt11B.1.1.3070.002532
ORF7b25L25FCttTtt11B.1.1.3110.000358
ORF7b25L25FCttTtt11B.1.1.3170.000412
ORF7b25L25FCttTtt11B.1.1.3260.001761
ORF7b25L25FCttTtt11B.1.1.3720.000689
ORF7b25L25FCttTtt11B.1.1.3970.002252
ORF7b25L25FCttTtt11B.1.1.4400.011765
ORF7b25L25FCttTtt11B.1.1.4870.005587
ORF7b25L25FCttTtt11B.1.1.700.000341
ORF7b25L25FCttTtt11B.1.160.310.008065
ORF7b25L25FCttTtt11B.1.177.170.000821
ORF7b25L25FCttTtt11B.1.177.330.001645
ORF7b25L25FCttTtt11B.1.177.480.003125
ORF7b25L25FCttTtt11B.1.177.860.000183
ORF7b25L25FCttTtt11B.1.177.870.000728
ORF7b25L25FCttTtt11B.1.2220.001692
ORF7b25L25FCttTtt11B.1.2320.000537
ORF7b25L25FCttTtt11B.1.3490.000715
ORF7b25L25FCttTtt11B.1.351.10.038462
ORF7b25L25FCttTtt11B.1.36.10.00114
ORF7b25L25FCttTtt11B.1.3610.001289
ORF7b25L25FCttTtt11B.1.3690.000285
ORF7b25L25FCttTtt11B.1.4270.00005
ORF7b25L25FCttTtt11B.1.4450.011765
ORF7b25L25FCttTtt11B.1.4530.003236
ORF7b25L25FCttTtt11B.1.4620.007246
ORF7b25L25FCttTtt11B.1.619.10.000641
ORF7b25L25FCttTtt11B.60.00091
ORF7b25L25FCttTtt11C.360.000911
ORF7b25L25FCttTtt11P.1.120.000484
ORF7b25L25FCttTtt11P.1.170.000162
ORF7b25L25FCttTtt11P.30.001595
ORF7b25L25FCttTtt11P.60.003145
ORF7b25L25FCttTtt11Q.10.000126
ORF7b25L25FCttTtt11Q.30.000145

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

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