CoV-GLUE Mutation

CoV-GLUE Mutation: ORF = ORF7b : Mut = E33X

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORF	CodonNum	Mut	ORF1abMut	MutType	RefCodon	MutCodon	AACount	CodonCount	CodonProp	Genome Position
ORF7b	33	E33X		nonsyn	Gaa	Taa	1699	1698	0.999411	27852-27854
ORF7b	33	E33X		nonsyn	GaA	TaG	1699	1	0.000588581	27852-27854

Details of the mutation E33X within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORF	CodonNum	Mut	RefCodon	MutCodon	CodonCount	AACount	Lineage	LineageCodonProp
ORF7b	33	E33X	Gaa	Taa	1698	1699	All	0.000325
ORF7b	33	E33X	GaA	TaG	1	1699	All	0
ORF7b	33	E33X	Gaa	Taa	362	362	B.1.36.17	0.178854
ORF7b	33	E33X	Gaa	Taa	217	217	AY.4	0.000338
ORF7b	33	E33X	Gaa	Taa	217	217	B.1.618	0.875
ORF7b	33	E33X	Gaa	Taa	141	141	B.1.1.7	0.000126
ORF7b	33	E33X	Gaa	Taa	139	139	B.1.232	0.074691
ORF7b	33	E33X	Gaa	Taa	71	71	AY.9	0.004799
ORF7b	33	E33X	Gaa	Taa	49	49	B.1	0.000449
ORF7b	33	E33X	Gaa	Taa	40	40	AY.3	0.000398
ORF7b	33	E33X	Gaa	Taa	38	38	B.1.160	0.001185
ORF7b	33	E33X	Gaa	Taa	37	37	AY.43	0.000164
ORF7b	33	E33X	Gaa	Taa	29	29	P.2	0.005412
ORF7b	33	E33X	Gaa	Taa	22	22	B.1.617.2	0.000083
ORF7b	33	E33X	Gaa	Taa	15	15	B.1.582	0.00736
ORF7b	33	E33X	Gaa	Taa	14	14	B.1.2	0.000123
ORF7b	33	E33X	Gaa	Taa	13	13	B.1.1	0.000236
ORF7b	33	E33X	Gaa	Taa	12	13	B.1.1.33	0.005051
ORF7b	33	E33X	GaA	TaG	1	13	B.1.1.33	0.000421
ORF7b	33	E33X	Gaa	Taa	13	13	B.1.167	0.101562
ORF7b	33	E33X	Gaa	Taa	13	13	C.16	0.013786
ORF7b	33	E33X	Gaa	Taa	12	12	AY.47	0.000373
ORF7b	33	E33X	Gaa	Taa	10	10	B.1.1.39	0.005097
ORF7b	33	E33X	Gaa	Taa	10	10	B.1.177	0.000132
ORF7b	33	E33X	Gaa	Taa	10	10	B.1.346	0.013106
ORF7b	33	E33X	Gaa	Taa	9	9	AY.25	0.000054
ORF7b	33	E33X	Gaa	Taa	8	8	B.1.1.306	0.003507
ORF7b	33	E33X	Gaa	Taa	8	8	B.1.177.43	0.011817
ORF7b	33	E33X	Gaa	Taa	7	7	AY.23	0.000488
ORF7b	33	E33X	Gaa	Taa	7	7	B.1.1.63	0.002701
ORF7b	33	E33X	Gaa	Taa	6	6	AY.103	0.000037
ORF7b	33	E33X	Gaa	Taa	6	6	AY.39	0.000148
ORF7b	33	E33X	Gaa	Taa	6	6	B.1.258	0.000399
ORF7b	33	E33X	Gaa	Taa	6	6	B.1.525	0.000679
ORF7b	33	E33X	Gaa	Taa	6	6	B.1.526	0.000141
ORF7b	33	E33X	Gaa	Taa	6	6	P.1	0.000095
ORF7b	33	E33X	Gaa	Taa	5	5	B.1.351	0.000149
ORF7b	33	E33X	Gaa	Taa	5	5	B.1.36	0.00073
ORF7b	33	E33X	Gaa	Taa	5	5	B.1.36.31	0.008757
ORF7b	33	E33X	Gaa	Taa	5	5	B.1.429	0.000118
ORF7b	33	E33X	Gaa	Taa	4	4	AY.44	0.000024
ORF7b	33	E33X	Gaa	Taa	4	4	AY.51	0.003636
ORF7b	33	E33X	Gaa	Taa	4	4	B.1.1.28	0.001245
ORF7b	33	E33X	Gaa	Taa	4	4	B.1.221	0.000284
ORF7b	33	E33X	Gaa	Taa	4	4	B.1.617.1	0.000516
ORF7b	33	E33X	Gaa	Taa	3	3	AY.42	0.000121
ORF7b	33	E33X	Gaa	Taa	3	3	AY.5	0.000062
ORF7b	33	E33X	Gaa	Taa	3	3	AY.5.3	0.001012
ORF7b	33	E33X	Gaa	Taa	3	3	AY.6	0.000123
ORF7b	33	E33X	Gaa	Taa	3	3	AY.9.2	0.00011
ORF7b	33	E33X	Gaa	Taa	3	3	B.1.1.362	0.016854
ORF7b	33	E33X	Gaa	Taa	3	3	B.1.36.8	0.003
ORF7b	33	E33X	Gaa	Taa	3	3	B.1.575	0.00091
ORF7b	33	E33X	Gaa	Taa	2	2	AY.102	0.000053
ORF7b	33	E33X	Gaa	Taa	2	2	AY.34.1	0.00102
ORF7b	33	E33X	Gaa	Taa	2	2	AY.41	0.000588
ORF7b	33	E33X	Gaa	Taa	2	2	AY.54	0.000191
ORF7b	33	E33X	Gaa	Taa	2	2	AY.87	0.001665
ORF7b	33	E33X	Gaa	Taa	2	2	B.1.1.25	0.001137
ORF7b	33	E33X	Gaa	Taa	2	2	B.1.1.46	0.008734
ORF7b	33	E33X	Gaa	Taa	2	2	B.1.252	0.013245
ORF7b	33	E33X	Gaa	Taa	2	2	B.1.627	0.00404
ORF7b	33	E33X	Gaa	Taa	1	1	A.23.1	0.000704
ORF7b	33	E33X	Gaa	Taa	1	1	AE.8	0.000489
ORF7b	33	E33X	Gaa	Taa	1	1	AY.100	0.000046
ORF7b	33	E33X	Gaa	Taa	1	1	AY.109	0.00074
ORF7b	33	E33X	Gaa	Taa	1	1	AY.119	0.000035
ORF7b	33	E33X	Gaa	Taa	1	1	AY.120	0.000037
ORF7b	33	E33X	Gaa	Taa	1	1	AY.120.1	0.000321
ORF7b	33	E33X	Gaa	Taa	1	1	AY.20	0.000039
ORF7b	33	E33X	Gaa	Taa	1	1	AY.27	0.000065
ORF7b	33	E33X	Gaa	Taa	1	1	AY.33	0.000067
ORF7b	33	E33X	Gaa	Taa	1	1	AY.39.1	0.00004
ORF7b	33	E33X	Gaa	Taa	1	1	AY.4.1	0.000737
ORF7b	33	E33X	Gaa	Taa	1	1	AY.4.2	0.000022
ORF7b	33	E33X	Gaa	Taa	1	1	AY.4.2.1	0.000149
ORF7b	33	E33X	Gaa	Taa	1	1	AY.4.5	0.000107
ORF7b	33	E33X	Gaa	Taa	1	1	AY.45	0.000122
ORF7b	33	E33X	Gaa	Taa	1	1	AY.5.4	0.000277
ORF7b	33	E33X	Gaa	Taa	1	1	AY.61	0.000105
ORF7b	33	E33X	Gaa	Taa	1	1	AY.67	0.000464
ORF7b	33	E33X	Gaa	Taa	1	1	AY.75	0.000056
ORF7b	33	E33X	Gaa	Taa	1	1	AY.77	0.001127
ORF7b	33	E33X	Gaa	Taa	1	1	AY.95	0.000761
ORF7b	33	E33X	Gaa	Taa	1	1	AZ.1	0.000867
ORF7b	33	E33X	Gaa	Taa	1	1	B.1.1.10	0.001115
ORF7b	33	E33X	Gaa	Taa	1	1	B.1.1.216	0.00089
ORF7b	33	E33X	Gaa	Taa	1	1	B.1.1.284	0.000107
ORF7b	33	E33X	Gaa	Taa	1	1	B.1.1.316	0.000925
ORF7b	33	E33X	Gaa	Taa	1	1	B.1.1.318	0.000302
ORF7b	33	E33X	Gaa	Taa	1	1	B.1.1.434	0.000349
ORF7b	33	E33X	Gaa	Taa	1	1	B.1.1.435	0.034483
ORF7b	33	E33X	Gaa	Taa	1	1	B.1.1.448	0.002033
ORF7b	33	E33X	Gaa	Taa	1	1	B.1.1.519	0.00004
ORF7b	33	E33X	Gaa	Taa	1	1	B.1.113	0.015625
ORF7b	33	E33X	Gaa	Taa	1	1	B.1.139	0.000733
ORF7b	33	E33X	Gaa	Taa	1	1	B.1.160.16	0.000929
ORF7b	33	E33X	Gaa	Taa	1	1	B.1.177.15	0.000631
ORF7b	33	E33X	Gaa	Taa	1	1	B.1.177.19	0.001431
ORF7b	33	E33X	Gaa	Taa	1	1	B.1.177.24	0.001295
ORF7b	33	E33X	Gaa	Taa	1	1	B.1.177.52	0.001757
ORF7b	33	E33X	Gaa	Taa	1	1	B.1.258.11	0.000396
ORF7b	33	E33X	Gaa	Taa	1	1	B.1.260	0.003344
ORF7b	33	E33X	Gaa	Taa	1	1	B.1.313	0.006579
ORF7b	33	E33X	Gaa	Taa	1	1	B.1.36.22	0.001208
ORF7b	33	E33X	Gaa	Taa	1	1	B.1.390	0.010638
ORF7b	33	E33X	Gaa	Taa	1	1	B.1.391	0.001127
ORF7b	33	E33X	Gaa	Taa	1	1	B.1.438.1	0.000107
ORF7b	33	E33X	Gaa	Taa	1	1	B.1.466.2	0.000391
ORF7b	33	E33X	Gaa	Taa	1	1	B.1.518	0.011765
ORF7b	33	E33X	Gaa	Taa	1	1	B.1.620	0.000946
ORF7b	33	E33X	Gaa	Taa	1	1	B.6.6	0.000889
ORF7b	33	E33X	Gaa	Taa	1	1	C.37	0.000116
ORF7b	33	E33X	Gaa	Taa	1	1	D.2	0.000075
ORF7b	33	E33X	Gaa	Taa	1	1	P.1.12	0.000484
ORF7b	33	E33X	Gaa	Taa	1	1	Q.1	0.000126
ORF7b	33	E33X	Gaa	Taa	1	1	Q.3	0.000145
ORF7b	33	E33X	Gaa	Taa	1	1	Q.8	0.000165
ORF7b	33	E33X	Gaa	Taa	1	1	R.1	0.00009

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.