CoV-GLUE Mutation

CoV-GLUE Mutation: ORF = ORF7b : Mut = E33V

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORF	CodonNum	Mut	ORF1abMut	MutType	RefCodon	MutCodon	AACount	CodonCount	CodonProp	Genome Position
ORF7b	33	E33V		nonsyn	gAa	gTa	3655	3655	1	27852-27854

Details of the mutation E33V within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORF	CodonNum	Mut	RefCodon	MutCodon	CodonCount	AACount	Lineage	LineageCodonProp
ORF7b	33	E33V	gAa	gTa	3655	3655	All	0.000699
ORF7b	33	E33V	gAa	gTa	3253	3253	AY.14	0.286305
ORF7b	33	E33V	gAa	gTa	75	75	B.1.617.2	0.000282
ORF7b	33	E33V	gAa	gTa	52	52	AY.19	0.059293
ORF7b	33	E33V	gAa	gTa	42	42	AY.54	0.004005
ORF7b	33	E33V	gAa	gTa	28	28	AY.38	0.013979
ORF7b	33	E33V	gAa	gTa	25	25	AY.44	0.000152
ORF7b	33	E33V	gAa	gTa	20	20	AY.98	0.00158
ORF7b	33	E33V	gAa	gTa	16	16	AY.13	0.002576
ORF7b	33	E33V	gAa	gTa	13	13	AY.4	0.00002
ORF7b	33	E33V	gAa	gTa	13	13	AY.78	0.020031
ORF7b	33	E33V	gAa	gTa	11	11	AY.64	0.006548
ORF7b	33	E33V	gAa	gTa	8	8	AY.75.1	0.001442
ORF7b	33	E33V	gAa	gTa	7	7	AY.43	0.000031
ORF7b	33	E33V	gAa	gTa	6	6	AY.62	0.002614
ORF7b	33	E33V	gAa	gTa	6	6	AY.68	0.001642
ORF7b	33	E33V	gAa	gTa	6	6	B.1.177	0.000079
ORF7b	33	E33V	gAa	gTa	5	5	AY.102	0.000133
ORF7b	33	E33V	gAa	gTa	4	4	AY.75	0.000224
ORF7b	33	E33V	gAa	gTa	4	4	B.1.1	0.000073
ORF7b	33	E33V	gAa	gTa	3	3	AY.23	0.000209
ORF7b	33	E33V	gAa	gTa	3	3	AY.39	0.000074
ORF7b	33	E33V	gAa	gTa	3	3	AY.59	0.001589
ORF7b	33	E33V	gAa	gTa	3	3	AY.86	0.00249
ORF7b	33	E33V	gAa	gTa	3	3	AY.87	0.002498
ORF7b	33	E33V	gAa	gTa	3	3	B.1.258.17	0.000312
ORF7b	33	E33V	gAa	gTa	2	2	AY.103	0.000012
ORF7b	33	E33V	gAa	gTa	2	2	AY.113	0.000285
ORF7b	33	E33V	gAa	gTa	2	2	AY.16.1	0.00094
ORF7b	33	E33V	gAa	gTa	2	2	AY.3	0.00002
ORF7b	33	E33V	gAa	gTa	2	2	AY.46.1	0.002053
ORF7b	33	E33V	gAa	gTa	2	2	AY.46.6	0.000144
ORF7b	33	E33V	gAa	gTa	2	2	AY.47	0.000062
ORF7b	33	E33V	gAa	gTa	2	2	AY.5	0.000041
ORF7b	33	E33V	gAa	gTa	2	2	AY.61	0.00021
ORF7b	33	E33V	gAa	gTa	2	2	AY.65	0.001066
ORF7b	33	E33V	gAa	gTa	2	2	B.1	0.000018
ORF7b	33	E33V	gAa	gTa	2	2	B.1.1.7	0.000002
ORF7b	33	E33V	gAa	gTa	1	1	AY.110	0.000113
ORF7b	33	E33V	gAa	gTa	1	1	AY.121	0.000135
ORF7b	33	E33V	gAa	gTa	1	1	AY.16	0.00038
ORF7b	33	E33V	gAa	gTa	1	1	AY.30	0.000396
ORF7b	33	E33V	gAa	gTa	1	1	AY.32	0.000532
ORF7b	33	E33V	gAa	gTa	1	1	AY.4.2	0.000022
ORF7b	33	E33V	gAa	gTa	1	1	AY.42	0.00004
ORF7b	33	E33V	gAa	gTa	1	1	AY.45	0.000122
ORF7b	33	E33V	gAa	gTa	1	1	AY.46	0.000104
ORF7b	33	E33V	gAa	gTa	1	1	AY.49	0.003195
ORF7b	33	E33V	gAa	gTa	1	1	AY.50	0.000799
ORF7b	33	E33V	gAa	gTa	1	1	AY.51	0.000909
ORF7b	33	E33V	gAa	gTa	1	1	AY.55	0.000917
ORF7b	33	E33V	gAa	gTa	1	1	AY.7	0.000196
ORF7b	33	E33V	gAa	gTa	1	1	AY.72	0.001361
ORF7b	33	E33V	gAa	gTa	1	1	AY.9.2	0.000037
ORF7b	33	E33V	gAa	gTa	1	1	B	0.000128
ORF7b	33	E33V	gAa	gTa	1	1	B.1.1.1	0.000327
ORF7b	33	E33V	gAa	gTa	1	1	B.1.2	0.000009

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.