CoV-GLUE Mutation

CoV-GLUE Mutation: ORF = ORF7b : Mut = E33G

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORF	CodonNum	Mut	ORF1abMut	MutType	RefCodon	MutCodon	AACount	CodonCount	CodonProp	Genome Position
ORF7b	33	E33G		nonsyn	gAa	gGa	559	557	0.996422	27852-27854
ORF7b	33	E33G		nonsyn	gAA	gGG	559	1	0.00178891	27852-27854
ORF7b	33	E33G		nonsyn	gAA	gGT	559	1	0.00178891	27852-27854

Details of the mutation E33G within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORF	CodonNum	Mut	RefCodon	MutCodon	CodonCount	AACount	Lineage	LineageCodonProp
ORF7b	33	E33G	gAa	gGa	557	559	All	0.000107
ORF7b	33	E33G	gAA	gGG	1	559	All	0
ORF7b	33	E33G	gAA	gGT	1	559	All	0
ORF7b	33	E33G	gAa	gGa	469	469	AY.103	0.002912
ORF7b	33	E33G	gAa	gGa	32	32	B.1.1.7	0.000029
ORF7b	33	E33G	gAa	gGa	10	10	AY.44	0.000061
ORF7b	33	E33G	gAa	gGa	5	5	B.1.617.2	0.000019
ORF7b	33	E33G	gAa	gGa	4	4	AY.25	0.000024
ORF7b	33	E33G	gAa	gGa	4	4	AY.4	0.000006
ORF7b	33	E33G	gAa	gGa	2	4	B.1.1.33	0.000842
ORF7b	33	E33G	gAA	gGG	1	4	B.1.1.33	0.000421
ORF7b	33	E33G	gAA	gGT	1	4	B.1.1.33	0.000421
ORF7b	33	E33G	gAa	gGa	4	4	B.1.177.60	0.000874
ORF7b	33	E33G	gAa	gGa	3	3	B.1.2	0.000026
ORF7b	33	E33G	gAa	gGa	3	3	B.1.595	0.000783
ORF7b	33	E33G	gAa	gGa	3	3	B.1.637	0.000219
ORF7b	33	E33G	gAa	gGa	2	2	AY.4.2	0.000043
ORF7b	33	E33G	gAa	gGa	2	2	B.1	0.000018
ORF7b	33	E33G	gAa	gGa	1	1	AY.105	0.000643
ORF7b	33	E33G	gAa	gGa	1	1	AY.119	0.000035
ORF7b	33	E33G	gAa	gGa	1	1	AY.121	0.000135
ORF7b	33	E33G	gAa	gGa	1	1	AY.23.1	0.000417
ORF7b	33	E33G	gAa	gGa	1	1	AY.39	0.000025
ORF7b	33	E33G	gAa	gGa	1	1	AY.98	0.000079
ORF7b	33	E33G	gAa	gGa	1	1	B.1.177	0.000013
ORF7b	33	E33G	gAa	gGa	1	1	B.1.429	0.000024
ORF7b	33	E33G	gAa	gGa	1	1	B.1.459	0.004082
ORF7b	33	E33G	gAa	gGa	1	1	B.1.471	0.002732
ORF7b	33	E33G	gAa	gGa	1	1	B.1.621	0.000089
ORF7b	33	E33G	gAa	gGa	1	1	P.1	0.000016
ORF7b	33	E33G	gAa	gGa	1	1	P.1.7	0.000319
ORF7b	33	E33G	gAa	gGa	1	1	P.3	0.001595

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.