CoV-GLUE Mutation

CoV-GLUE Mutation: ORF = ORF7b : Mut = E33E

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORF	CodonNum	Mut	ORF1abMut	MutType	RefCodon	MutCodon	AACount	CodonCount	CodonProp	Genome Position
ORF7b	33	E33E		syn	gaA	gaG	83	83	1	27852-27854

Details of the mutation E33E within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORF	CodonNum	Mut	RefCodon	MutCodon	CodonCount	AACount	Lineage	LineageCodonProp
ORF7b	33	E33E	gaA	gaG	83	83	All	0.000016
ORF7b	33	E33E	gaA	gaG	16	16	B.1.2	0.000141
ORF7b	33	E33E	gaA	gaG	13	13	AY.61	0.001362
ORF7b	33	E33E	gaA	gaG	11	11	B.1.1.519	0.000437
ORF7b	33	E33E	gaA	gaG	10	10	AY.44	0.000061
ORF7b	33	E33E	gaA	gaG	5	5	AY.4	0.000008
ORF7b	33	E33E	gaA	gaG	4	4	B.1	0.000037
ORF7b	33	E33E	gaA	gaG	4	4	B.1.1.7	0.000004
ORF7b	33	E33E	gaA	gaG	4	4	B.1.617.2	0.000015
ORF7b	33	E33E	gaA	gaG	2	2	AY.121	0.000271
ORF7b	33	E33E	gaA	gaG	2	2	B.1.1.33	0.000842
ORF7b	33	E33E	gaA	gaG	2	2	B.1.1.512	0.057143
ORF7b	33	E33E	gaA	gaG	2	2	B.1.243	0.000139
ORF7b	33	E33E	gaA	gaG	2	2	B.1.351	0.000059
ORF7b	33	E33E	gaA	gaG	1	1	AY.103	0.000006
ORF7b	33	E33E	gaA	gaG	1	1	AY.43	0.000004
ORF7b	33	E33E	gaA	gaG	1	1	AY.47	0.000031
ORF7b	33	E33E	gaA	gaG	1	1	B.1.1.416	0.000905
ORF7b	33	E33E	gaA	gaG	1	1	B.1.177	0.000013
ORF7b	33	E33E	gaA	gaG	1	1	P.1	0.000016

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.