CoV-GLUE Mutation

CoV-GLUE Mutation: ORF = ORF7b : CodonNum = 15 & Codon = gcA

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORF	CodonNum	Mut	ORF1abMut	MutType	RefCodon	MutCodon	AACount	CodonCount	CodonProp	Genome Position
ORF7b	15	A15A		syn	gcC	gcA	26763	25596	0.956395	27798-27800

Details of the mutation no within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORF	CodonNum	Mut	RefCodon	MutCodon	CodonCount	AACount	Lineage	LineageCodonProp
ORF7b	15	A15A	gcC	gcA	25596	26763	All	0.004896
ORF7b	15	A15A	gcC	gcA	10832	10833	B.1.258	0.720836
ORF7b	15	A15A	gcC	gcA	8563	8563	B.1.258.17	0.89031
ORF7b	15	A15A	gcC	gcA	2351	2351	B.1.258.11	0.931827
ORF7b	15	A15A	gcC	gcA	784	784	B.1.258.14	0.768627
ORF7b	15	A15A	gcC	gcA	603	604	B.1.258.16	0.986907
ORF7b	15	A15A	gcC	gcA	483	483	B.1.258.7	0.923518
ORF7b	15	A15A	gcC	gcA	359	359	B.1.258.22	0.957333
ORF7b	15	A15A	gcC	gcA	270	270	B.1.258.4	0.931034
ORF7b	15	A15A	gcC	gcA	249	255	B.1	0.002281
ORF7b	15	A15A	gcC	gcA	2	148	AY.4	0.000003
ORF7b	15	A15A	gcC	gcA	139	139	B.1.258.19	0.985816
ORF7b	15	A15A	gcC	gcA	128	128	B.1.258.21	0.992248
ORF7b	15	A15A	gcC	gcA	104	104	B.1.258.12	0.818898
ORF7b	15	A15A	gcC	gcA	100	100	B.1.258.5	0.877193
ORF7b	15	A15A	gcC	gcA	87	87	B.1.258.10	0.988636
ORF7b	15	A15A	gcC	gcA	5	83	B.1.617.2	0.000019
ORF7b	15	A15A	gcC	gcA	10	74	B.1.1.7	0.000009
ORF7b	15	A15A	gcC	gcA	59	59	B.1.258.20	0.936508
ORF7b	15	A15A	gcC	gcA	29	56	B.1.177	0.000382
ORF7b	15	A15A	gcC	gcA	51	51	B.1.258.15	0.962264
ORF7b	15	A15A	gcC	gcA	49	49	B.1.258.6	0.960784
ORF7b	15	A15A	gcC	gcA	2	45	AY.103	0.000012
ORF7b	15	A15A	gcC	gcA	33	38	B.1.160	0.001029
ORF7b	15	A15A	gcC	gcA	1	38	B.1.391	0.001127
ORF7b	15	A15A	gcC	gcA	31	31	B.1.258.24	0.333333
ORF7b	15	A15A	gcC	gcA	30	30	B.1.258.23	0.714286
ORF7b	15	A15A	gcC	gcA	21	25	B.1.1	0.000381
ORF7b	15	A15A	gcC	gcA	17	22	B.1.221	0.001208
ORF7b	15	A15A	gcC	gcA	20	20	AY.24	0.008621
ORF7b	15	A15A	gcC	gcA	19	20	B.1.609	0.009108
ORF7b	15	A15A	gcC	gcA	3	15	AY.43	0.000013
ORF7b	15	A15A	gcC	gcA	4	14	AY.25	0.000024
ORF7b	15	A15A	gcC	gcA	2	14	AY.98	0.000158
ORF7b	15	A15A	gcC	gcA	11	11	B.1.222	0.018613
ORF7b	15	A15A	gcC	gcA	1	11	P.1	0.000016
ORF7b	15	A15A	gcC	gcA	3	10	B.1.2	0.000026
ORF7b	15	A15A	gcC	gcA	10	10	B.1.258.18	1
ORF7b	15	A15A	gcC	gcA	10	10	B.1.367	0.007924
ORF7b	15	A15A	gcC	gcA	9	9	A	0.003483
ORF7b	15	A15A	gcC	gcA	8	8	B	0.001022
ORF7b	15	A15A	gcC	gcA	1	8	B.1.351	0.00003
ORF7b	15	A15A	gcC	gcA	3	7		0.166667
ORF7b	15	A15A	gcC	gcA	7	7	B.4.1	0.132075
ORF7b	15	A15A	gcC	gcA	5	5	AY.29	0.000079
ORF7b	15	A15A	gcC	gcA	1	4	AY.20	0.000039
ORF7b	15	A15A	gcC	gcA	2	4	AY.39.1	0.000079
ORF7b	15	A15A	gcC	gcA	4	4	B.1.177.21	0.000306
ORF7b	15	A15A	gcC	gcA	4	4	B.1.177.73	0.002265
ORF7b	15	A15A	gcC	gcA	4	4	B.1.177.86	0.000734
ORF7b	15	A15A	gcC	gcA	4	4	B.1.237	0.0199
ORF7b	15	A15A	gcC	gcA	4	4	B.1.576	0.003626
ORF7b	15	A15A	gcC	gcA	1	3	AY.33	0.000067
ORF7b	15	A15A	gcC	gcA	2	3	AY.36	0.000296
ORF7b	15	A15A	gcC	gcA	3	3	AY.6	0.000123
ORF7b	15	A15A	gcC	gcA	3	3	B.1.1.70	0.001023
ORF7b	15	A15A	gcC	gcA	2	3	B.1.177.7	0.00033
ORF7b	15	A15A	gcC	gcA	3	3	B.1.411	0.011111
ORF7b	15	A15A	gcC	gcA	3	3	B.1.590	0.013636
ORF7b	15	A15A	gcC	gcA	3	3	B.1.597	0.013889
ORF7b	15	A15A	gcC	gcA	3	3	B.1.600	0.017544
ORF7b	15	A15A	gcC	gcA	1	2	AY.5	0.000021
ORF7b	15	A15A	gcC	gcA	2	2	AY.99.2	0.000184
ORF7b	15	A15A	gcC	gcA	2	2	B.1.1.153	0.002191
ORF7b	15	A15A	gcC	gcA	2	2	B.1.1.409	0.005666
ORF7b	15	A15A	gcC	gcA	2	2	B.1.177.6	0.001953
ORF7b	15	A15A	gcC	gcA	2	2	B.1.627	0.00404
ORF7b	15	A15A	gcC	gcA	1	1	AY.39	0.000025
ORF7b	15	A15A	gcC	gcA	1	1	AY.52	0.000814
ORF7b	15	A15A	gcC	gcA	1	1	AY.7.1	0.000113
ORF7b	15	A15A	gcC	gcA	1	1	AY.7.2	0.000559
ORF7b	15	A15A	gcC	gcA	1	1	AY.9.1	0.000084
ORF7b	15	A15A	gcC	gcA	1	1	B.1.1.282	0.011628
ORF7b	15	A15A	gcC	gcA	1	1	B.1.1.297	0.002237
ORF7b	15	A15A	gcC	gcA	1	1	B.1.1.39	0.00051
ORF7b	15	A15A	gcC	gcA	1	1	B.1.120	0.007692
ORF7b	15	A15A	gcC	gcA	1	1	B.1.142	0.002899
ORF7b	15	A15A	gcC	gcA	1	1	B.1.146	0.004237
ORF7b	15	A15A	gcC	gcA	1	1	B.1.149	0.003425
ORF7b	15	A15A	gcC	gcA	1	1	B.1.157	0.002985
ORF7b	15	A15A	gcC	gcA	1	1	B.1.177.28	0.007407
ORF7b	15	A15A	gcC	gcA	1	1	B.1.177.4	0.000211
ORF7b	15	A15A	gcC	gcA	1	1	B.1.221.1	0.002907
ORF7b	15	A15A	gcC	gcA	1	1	B.1.240	0.000216
ORF7b	15	A15A	gcC	gcA	1	1	B.1.242	0.018868
ORF7b	15	A15A	gcC	gcA	1	1	B.1.293	0.0125
ORF7b	15	A15A	gcC	gcA	1	1	B.1.3	0.002618
ORF7b	15	A15A	gcC	gcA	1	1	B.1.301	0.005917
ORF7b	15	A15A	gcC	gcA	1	1	B.1.36.10	0.004785
ORF7b	15	A15A	gcC	gcA	1	1	B.1.362	0.001541
ORF7b	15	A15A	gcC	gcA	1	1	B.1.375	0.00082
ORF7b	15	A15A	gcC	gcA	1	1	B.1.380	0.006623
ORF7b	15	A15A	gcC	gcA	1	1	B.1.406	0.006061
ORF7b	15	A15A	gcC	gcA	1	1	B.1.432	0.011236
ORF7b	15	A15A	gcC	gcA	1	1	B.1.596	0.000087
ORF7b	15	A15A	gcC	gcA	1	1	B.1.599	0.00365
ORF7b	15	A15A	gcC	gcA	1	1	B.1.601	0.030303
ORF7b	15	A15A	gcC	gcA	1	1	B.1.623	0.000536

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.