CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF7a : Mut = N52S

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF7a52N52SnonsynaAcaGc72580.80555627547-27549
ORF7a52N52SnonsynaACaGT7270.097222227547-27549
ORF7a52N52SnonsynAAcTCc7230.041666727547-27549
ORF7a52N52SnonsynAACTCT7230.041666727547-27549
ORF7a52N52SnonsynAACTCA7210.013888927547-27549

Details of the mutation N52S within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF7a52N52SaAcaGc5872All0.000011
ORF7a52N52SaACaGT772All0.000001
ORF7a52N52SAACTCT372All0.000001
ORF7a52N52SAAcTCc372All0.000001
ORF7a52N52SAACTCA172All0
ORF7a52N52SaAcaGc1111D.20.000825
ORF7a52N52SaACaGT510AY.250.00003
ORF7a52N52SAACTCT210AY.250.000012
ORF7a52N52SaAcaGc210AY.250.000012
ORF7a52N52SAACTCA110AY.250.000006
ORF7a52N52SaAcaGc1010P.1.100.002695
ORF7a52N52SaAcaGc56B.1.1.70.000004
ORF7a52N52SaACaGT16B.1.1.70.000001
ORF7a52N52SaAcaGc46B.1.617.20.000015
ORF7a52N52SAACTCT16B.1.617.20.000004
ORF7a52N52SAAcTCc16B.1.617.20.000004
ORF7a52N52SaAcaGc33P.1.10.000953
ORF7a52N52SAAcTCc220.111111
ORF7a52N52SaAcaGc12AY.1190.000035
ORF7a52N52SaACaGT12AY.1190.000035
ORF7a52N52SaAcaGc22AY.30.00002
ORF7a52N52SaAcaGc22AY.40.000003
ORF7a52N52SaAcaGc22B.10.000018
ORF7a52N52SaAcaGc22C.140.008658
ORF7a52N52SaAcaGc11AY.290.000016
ORF7a52N52SaAcaGc11AY.39.10.00004
ORF7a52N52SaAcaGc11AY.430.000004
ORF7a52N52SaAcaGc11AY.450.000122
ORF7a52N52SaAcaGc11AY.46.20.000635
ORF7a52N52SaAcaGc11AY.600.000938
ORF7a52N52SaAcaGc11AY.9.10.000084
ORF7a52N52SaAcaGc11AY.9.20.000037
ORF7a52N52SaAcaGc11B.1.1.3180.000302
ORF7a52N52SaAcaGc11B.1.1.5190.00004
ORF7a52N52SaAcaGc11B.1.1770.000013
ORF7a52N52SaAcaGc11B.1.20.000009
ORF7a52N52SaAcaGc11B.1.4290.000024
ORF7a52N52SaAcaGc11B.1.5750.000303

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.