CoV-GLUE | Mutations | Mutation
Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):
ORF | CodonNum | Mut | ORF1abMut | MutType | RefCodon | MutCodon | AACount | CodonCount | CodonProp | Genome Position |
ORF7a | 22 | E22D | nonsyn | gaG | gaT | 6055 | 6046 | 0.998514 | 27457-27459 | |
ORF7a | 22 | E22D | nonsyn | gaG | gaC | 6055 | 9 | 0.00148637 | 27457-27459 |
Details of the mutation E22D within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):
ORF | CodonNum | Mut | RefCodon | MutCodon | CodonCount | AACount | Lineage | LineageCodonProp |
ORF7a | 22 | E22D | gaG | gaT | 6046 | 6055 | All | 0.001156 |
ORF7a | 22 | E22D | gaG | gaC | 9 | 6055 | All | 0.000002 |
ORF7a | 22 | E22D | gaG | gaT | 1547 | 1547 | B.1.619.1 | 0.992303 |
ORF7a | 22 | E22D | gaG | gaT | 1057 | 1057 | B.1.619 | 0.920732 |
ORF7a | 22 | E22D | gaG | gaT | 804 | 805 | AY.4 | 0.001251 |
ORF7a | 22 | E22D | gaG | gaC | 1 | 805 | AY.4 | 0.000002 |
ORF7a | 22 | E22D | gaG | gaT | 689 | 690 | B.1.1.7 | 0.000617 |
ORF7a | 22 | E22D | gaG | gaC | 1 | 690 | B.1.1.7 | 0.000001 |
ORF7a | 22 | E22D | gaG | gaT | 472 | 472 | AY.43 | 0.002091 |
ORF7a | 22 | E22D | gaG | gaT | 163 | 165 | B.1.617.2 | 0.000614 |
ORF7a | 22 | E22D | gaG | gaC | 2 | 165 | B.1.617.2 | 0.000008 |
ORF7a | 22 | E22D | gaG | gaT | 128 | 128 | R.1 | 0.011521 |
ORF7a | 22 | E22D | gaG | gaT | 63 | 63 | AY.44 | 0.000383 |
ORF7a | 22 | E22D | gaG | gaT | 61 | 61 | AY.103 | 0.000379 |
ORF7a | 22 | E22D | gaG | gaT | 60 | 60 | AY.75 | 0.003361 |
ORF7a | 22 | E22D | gaG | gaT | 57 | 57 | AY.5 | 0.001177 |
ORF7a | 22 | E22D | gaG | gaT | 54 | 54 | AY.120 | 0.002008 |
ORF7a | 22 | E22D | gaG | gaT | 51 | 51 | P.1 | 0.000803 |
ORF7a | 22 | E22D | gaG | gaT | 42 | 42 | B.1.526 | 0.000987 |
ORF7a | 22 | E22D | gaG | gaT | 41 | 41 | AY.39 | 0.001013 |
ORF7a | 22 | E22D | gaG | gaT | 38 | 39 | AY.25 | 0.000229 |
ORF7a | 22 | E22D | gaG | gaC | 1 | 39 | AY.25 | 0.000006 |
ORF7a | 22 | E22D | gaG | gaT | 36 | 36 | P.1.17 | 0.005823 |
ORF7a | 22 | E22D | gaG | gaT | 35 | 35 | B.1.258 | 0.002329 |
ORF7a | 22 | E22D | gaG | gaT | 33 | 33 | B.1.1.519 | 0.00131 |
ORF7a | 22 | E22D | gaG | gaT | 28 | 28 | B.1.160 | 0.000873 |
ORF7a | 22 | E22D | gaG | gaT | 27 | 27 | AY.20 | 0.001049 |
ORF7a | 22 | E22D | gaG | gaT | 27 | 27 | B.1.595 | 0.007046 |
ORF7a | 22 | E22D | gaG | gaT | 24 | 25 | B.1 | 0.00022 |
ORF7a | 22 | E22D | gaG | gaC | 1 | 25 | B.1 | 0.000009 |
ORF7a | 22 | E22D | gaG | gaT | 25 | 25 | Q.1 | 0.003158 |
ORF7a | 22 | E22D | gaG | gaT | 19 | 19 | B.1.617.1 | 0.00245 |
ORF7a | 22 | E22D | gaG | gaT | 18 | 18 | AY.16 | 0.006834 |
ORF7a | 22 | E22D | gaG | gaT | 17 | 18 | B.1.2 | 0.00015 |
ORF7a | 22 | E22D | gaG | gaC | 1 | 18 | B.1.2 | 0.000009 |
ORF7a | 22 | E22D | gaG | gaT | 14 | 14 | AY.102 | 0.000371 |
ORF7a | 22 | E22D | gaG | gaT | 14 | 14 | AY.3.1 | 0.001194 |
ORF7a | 22 | E22D | gaG | gaT | 14 | 14 | AY.47 | 0.000435 |
ORF7a | 22 | E22D | gaG | gaT | 14 | 14 | B.1.1.434 | 0.00488 |
ORF7a | 22 | E22D | gaG | gaT | 11 | 11 | B.1.1 | 0.0002 |
ORF7a | 22 | E22D | gaG | gaT | 10 | 10 | AY.3 | 0.000099 |
ORF7a | 22 | E22D | gaG | gaT | 10 | 10 | B.1.177 | 0.000132 |
ORF7a | 22 | E22D | gaG | gaT | 10 | 10 | B.1.385 | 0.106383 |
ORF7a | 22 | E22D | gaG | gaT | 10 | 10 | P.1.15 | 0.002323 |
ORF7a | 22 | E22D | gaG | gaT | 9 | 9 | AY.23 | 0.000628 |
ORF7a | 22 | E22D | gaG | gaT | 9 | 9 | AY.26 | 0.000255 |
ORF7a | 22 | E22D | gaG | gaT | 9 | 9 | B.1.367 | 0.007132 |
ORF7a | 22 | E22D | gaG | gaT | 9 | 9 | B.1.93 | 0.008403 |
ORF7a | 22 | E22D | gaG | gaT | 8 | 8 | AY.113 | 0.001139 |
ORF7a | 22 | E22D | gaG | gaT | 8 | 8 | AY.29 | 0.000126 |
ORF7a | 22 | E22D | gaG | gaT | 8 | 8 | AY.99.2 | 0.000737 |
ORF7a | 22 | E22D | gaG | gaT | 8 | 8 | B.1.369 | 0.002282 |
ORF7a | 22 | E22D | gaG | gaT | 8 | 8 | B.1.466 | 0.186047 |
ORF7a | 22 | E22D | gaG | gaT | 7 | 7 | AY.100 | 0.000322 |
ORF7a | 22 | E22D | gaG | gaT | 7 | 7 | AY.119 | 0.000247 |
ORF7a | 22 | E22D | gaG | gaT | 7 | 7 | AY.27 | 0.000453 |
ORF7a | 22 | E22D | gaG | gaT | 7 | 7 | AY.4.2 | 0.000152 |
ORF7a | 22 | E22D | gaG | gaT | 6 | 6 | AY.46 | 0.000624 |
ORF7a | 22 | E22D | gaG | gaT | 6 | 6 | B.1.36 | 0.000875 |
ORF7a | 22 | E22D | gaG | gaT | 6 | 6 | B.1.416 | 0.007614 |
ORF7a | 22 | E22D | gaG | gaT | 6 | 6 | B.1.429 | 0.000141 |
ORF7a | 22 | E22D | gaG | gaT | 5 | 5 | AY.75.1 | 0.000902 |
ORF7a | 22 | E22D | gaG | gaT | 5 | 5 | AY.9 | 0.000338 |
ORF7a | 22 | E22D | gaG | gaT | 5 | 5 | B.1.1.1 | 0.001633 |
ORF7a | 22 | E22D | gaG | gaT | 5 | 5 | B.1.177.17 | 0.004105 |
ORF7a | 22 | E22D | gaG | gaT | 4 | 4 | AY.116.1 | 0.001246 |
ORF7a | 22 | E22D | gaG | gaT | 4 | 4 | AY.33 | 0.000267 |
ORF7a | 22 | E22D | gaG | gaT | 4 | 4 | AY.92 | 0.001149 |
ORF7a | 22 | E22D | gaG | gaT | 4 | 4 | B.1.234 | 0.000528 |
ORF7a | 22 | E22D | gaG | gaT | 4 | 4 | P.1.7 | 0.001277 |
ORF7a | 22 | E22D | gaG | gaT | 3 | 3 | AY.106 | 0.001005 |
ORF7a | 22 | E22D | gaG | gaT | 3 | 3 | AY.107 | 0.001398 |
ORF7a | 22 | E22D | gaG | gaT | 3 | 3 | AY.118 | 0.000188 |
ORF7a | 22 | E22D | gaG | gaT | 3 | 3 | AY.13 | 0.000483 |
ORF7a | 22 | E22D | gaG | gaT | 3 | 3 | AY.4.5 | 0.000322 |
ORF7a | 22 | E22D | gaG | gaT | 3 | 3 | AY.42 | 0.000121 |
ORF7a | 22 | E22D | gaG | gaT | 3 | 3 | AY.7.1 | 0.000338 |
ORF7a | 22 | E22D | gaG | gaT | 3 | 3 | AY.71 | 0.001425 |
ORF7a | 22 | E22D | gaG | gaT | 3 | 3 | AY.84 | 0.001312 |
ORF7a | 22 | E22D | gaG | gaT | 3 | 3 | B.1.1.306 | 0.001315 |
ORF7a | 22 | E22D | gaG | gaT | 3 | 3 | B.1.243 | 0.000209 |
ORF7a | 22 | E22D | gaG | gaT | 3 | 3 | B.1.577 | 0.002062 |
ORF7a | 22 | E22D | gaG | gaT | 3 | 3 | B.1.621 | 0.000266 |
ORF7a | 22 | E22D | gaG | gaT | 3 | 3 | B.1.625 | 0.007059 |
ORF7a | 22 | E22D | gaG | gaT | 3 | 3 | C.37 | 0.000348 |
ORF7a | 22 | E22D | gaG | gaT | 2 | 2 | A | 0.000774 |
ORF7a | 22 | E22D | gaG | gaT | 2 | 2 | AY.1 | 0.000791 |
ORF7a | 22 | E22D | gaG | gaT | 2 | 2 | AY.10 | 0.00106 |
ORF7a | 22 | E22D | gaG | gaT | 2 | 2 | AY.117 | 0.000169 |
ORF7a | 22 | E22D | gaG | gaT | 2 | 2 | AY.120.2 | 0.002571 |
ORF7a | 22 | E22D | gaG | gaT | 2 | 2 | AY.121 | 0.000271 |
ORF7a | 22 | E22D | gaG | gaT | 2 | 2 | AY.19 | 0.002281 |
ORF7a | 22 | E22D | gaG | gaT | 2 | 2 | AY.41 | 0.000588 |
ORF7a | 22 | E22D | gaG | gaT | 2 | 2 | AY.45 | 0.000243 |
ORF7a | 22 | E22D | gaG | gaT | 2 | 2 | AY.46.4 | 0.000329 |
ORF7a | 22 | E22D | gaG | gaT | 2 | 2 | AY.46.6 | 0.000144 |
ORF7a | 22 | E22D | gaG | gaT | 2 | 2 | AY.56 | 0.00321 |
ORF7a | 22 | E22D | gaG | gaT | 2 | 2 | AY.61 | 0.00021 |
ORF7a | 22 | E22D | gaG | gaT | 2 | 2 | AY.98 | 0.000158 |
ORF7a | 22 | E22D | gaG | gaT | 2 | 2 | B | 0.000256 |
ORF7a | 22 | E22D | gaG | gaT | 2 | 2 | B.1.1.214 | 0.000111 |
ORF7a | 22 | E22D | gaG | gaT | 2 | 2 | B.1.1.216 | 0.001781 |
ORF7a | 22 | E22D | gaG | gaT | 2 | 2 | B.1.1.298 | 0.001724 |
ORF7a | 22 | E22D | gaG | gaT | 2 | 2 | B.1.1.316 | 0.00185 |
ORF7a | 22 | E22D | gaG | gaT | 2 | 2 | B.1.1.432 | 0.002532 |
ORF7a | 22 | E22D | gaG | gaT | 2 | 2 | B.1.1.528 | 0.009615 |
ORF7a | 22 | E22D | gaG | gaT | 2 | 2 | B.1.177.83 | 0.002963 |
ORF7a | 22 | E22D | gaG | gaT | 2 | 2 | B.1.210 | 0.004264 |
ORF7a | 22 | E22D | gaG | gaT | 2 | 2 | B.1.214.2 | 0.001199 |
ORF7a | 22 | E22D | gaG | gaT | 2 | 2 | B.1.258.11 | 0.000793 |
ORF7a | 22 | E22D | gaG | gaT | 2 | 2 | B.1.351 | 0.000059 |
ORF7a | 22 | E22D | gaG | gaT | 2 | 2 | B.1.427 | 0.000101 |
ORF7a | 22 | E22D | gaG | gaC | 2 | 2 | B.1.558 | 0.009132 |
ORF7a | 22 | E22D | gaG | gaT | 2 | 2 | B.40 | 0.000729 |
ORF7a | 22 | E22D | gaG | gaT | 2 | 2 | C.32 | 0.046512 |
ORF7a | 22 | E22D | gaG | gaT | 2 | 2 | D.2 | 0.00015 |
ORF7a | 22 | E22D | gaG | gaT | 2 | 2 | P.1.14 | 0.000096 |
ORF7a | 22 | E22D | gaG | gaT | 2 | 2 | P.3 | 0.00319 |
ORF7a | 22 | E22D | gaG | gaT | 1 | 1 | A.2.5 | 0.000499 |
ORF7a | 22 | E22D | gaG | gaT | 1 | 1 | A.2.5.2 | 0.001572 |
ORF7a | 22 | E22D | gaG | gaT | 1 | 1 | A.29 | 0.005319 |
ORF7a | 22 | E22D | gaG | gaT | 1 | 1 | AD.2 | 0.000219 |
ORF7a | 22 | E22D | gaG | gaT | 1 | 1 | AY.108 | 0.001103 |
ORF7a | 22 | E22D | gaG | gaT | 1 | 1 | AY.109 | 0.00074 |
ORF7a | 22 | E22D | gaG | gaT | 1 | 1 | AY.110 | 0.000113 |
ORF7a | 22 | E22D | gaG | gaT | 1 | 1 | AY.12 | 0.000316 |
ORF7a | 22 | E22D | gaG | gaT | 1 | 1 | AY.2 | 0.000356 |
ORF7a | 22 | E22D | gaG | gaT | 1 | 1 | AY.29.1 | 0.000221 |
ORF7a | 22 | E22D | gaG | gaT | 1 | 1 | AY.34 | 0.000097 |
ORF7a | 22 | E22D | gaG | gaT | 1 | 1 | AY.34.1 | 0.00051 |
ORF7a | 22 | E22D | gaG | gaT | 1 | 1 | AY.4.1 | 0.000737 |
ORF7a | 22 | E22D | gaG | gaT | 1 | 1 | AY.46.5 | 0.000198 |
ORF7a | 22 | E22D | gaG | gaT | 1 | 1 | AY.5.4 | 0.000277 |
ORF7a | 22 | E22D | gaG | gaT | 1 | 1 | AY.52 | 0.000814 |
ORF7a | 22 | E22D | gaG | gaT | 1 | 1 | AY.68 | 0.000274 |
ORF7a | 22 | E22D | gaG | gaT | 1 | 1 | AY.88 | 0.000884 |
ORF7a | 22 | E22D | gaG | gaT | 1 | 1 | AZ.2 | 0.000821 |
ORF7a | 22 | E22D | gaG | gaT | 1 | 1 | B.1.1.171 | 0.003676 |
ORF7a | 22 | E22D | gaG | gaT | 1 | 1 | B.1.1.254 | 0.011236 |
ORF7a | 22 | E22D | gaG | gaT | 1 | 1 | B.1.1.277 | 0.000759 |
ORF7a | 22 | E22D | gaG | gaT | 1 | 1 | B.1.1.33 | 0.000421 |
ORF7a | 22 | E22D | gaG | gaT | 1 | 1 | B.1.1.332 | 0.03125 |
ORF7a | 22 | E22D | gaG | gaT | 1 | 1 | B.1.1.359 | 0.027778 |
ORF7a | 22 | E22D | gaG | gaT | 1 | 1 | B.1.1.369 | 0.000446 |
ORF7a | 22 | E22D | gaG | gaT | 1 | 1 | B.1.1.37 | 0.000193 |
ORF7a | 22 | E22D | gaG | gaT | 1 | 1 | B.1.1.421 | 0.030303 |
ORF7a | 22 | E22D | gaG | gaT | 1 | 1 | B.1.177.19 | 0.001431 |
ORF7a | 22 | E22D | gaG | gaT | 1 | 1 | B.1.177.53 | 0.002392 |
ORF7a | 22 | E22D | gaG | gaT | 1 | 1 | B.1.177.54 | 0.000606 |
ORF7a | 22 | E22D | gaG | gaT | 1 | 1 | B.1.177.69 | 0.001484 |
ORF7a | 22 | E22D | gaG | gaT | 1 | 1 | B.1.177.7 | 0.000165 |
ORF7a | 22 | E22D | gaG | gaT | 1 | 1 | B.1.177.73 | 0.000566 |
ORF7a | 22 | E22D | gaG | gaT | 1 | 1 | B.1.177.82 | 0.000477 |
ORF7a | 22 | E22D | gaG | gaT | 1 | 1 | B.1.337 | 0.005587 |
ORF7a | 22 | E22D | gaG | gaT | 1 | 1 | B.1.426 | 0.001009 |
ORF7a | 22 | E22D | gaG | gaT | 1 | 1 | B.1.501 | 0.007353 |
ORF7a | 22 | E22D | gaG | gaT | 1 | 1 | B.1.503 | 0.002488 |
ORF7a | 22 | E22D | gaG | gaT | 1 | 1 | B.1.524 | 0.001406 |
ORF7a | 22 | E22D | gaG | gaT | 1 | 1 | B.1.575 | 0.000303 |
ORF7a | 22 | E22D | gaG | gaT | 1 | 1 | B.1.612 | 0.002653 |
ORF7a | 22 | E22D | gaG | gaT | 1 | 1 | B.6.6 | 0.000889 |
ORF7a | 22 | E22D | gaG | gaT | 1 | 1 | N.6 | 0.007092 |
ORF7a | 22 | E22D | gaG | gaT | 1 | 1 | P.1.2 | 0.001156 |
ORF7a | 22 | E22D | gaG | gaT | 1 | 1 | Q.8 | 0.000165 |
CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk
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