CoV-GLUE Mutation

CoV-GLUE Mutation: ORF = ORF7a : CodonNum = 95 & Codon = Taa

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORF	CodonNum	Mut	ORF1abMut	MutType	RefCodon	MutCodon	AACount	CodonCount	CodonProp	Genome Position
ORF7a	95	E95X		nonsyn	Gaa	Taa	3009	3005	0.998671	27676-27678

Details of the mutation no within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORF	CodonNum	Mut	RefCodon	MutCodon	CodonCount	AACount	Lineage	LineageCodonProp
ORF7a	95	E95X	Gaa	Taa	3005	3009	All	0.000575
ORF7a	95	E95X	Gaa	Taa	752	752	B.1.1.7	0.000673
ORF7a	95	E95X	Gaa	Taa	281	281	AY.9.2	0.010321
ORF7a	95	E95X	Gaa	Taa	262	262	B.1.617.2	0.000987
ORF7a	95	E95X	Gaa	Taa	248	248	AY.4	0.000386
ORF7a	95	E95X	Gaa	Taa	114	114	AY.103	0.000708
ORF7a	95	E95X	Gaa	Taa	113	113	AY.43	0.000501
ORF7a	95	E95X	Gaa	Taa	107	107	AY.5	0.002209
ORF7a	95	E95X	Gaa	Taa	65	65	AY.44	0.000396
ORF7a	95	E95X	Gaa	Taa	59	59	AY.102	0.001564
ORF7a	95	E95X	Gaa	Taa	56	56	AY.13	0.009015
ORF7a	95	E95X	Gaa	Taa	56	56	AY.23.1	0.023372
ORF7a	95	E95X	Gaa	Taa	48	48	AY.100	0.002208
ORF7a	95	E95X	Gaa	Taa	41	41	AY.39	0.001013
ORF7a	95	E95X	Gaa	Taa	41	41	AY.5.4	0.011345
ORF7a	95	E95X	Gaa	Taa	36	36	AY.25	0.000217
ORF7a	95	E95X	Gaa	Taa	31	31	B.1.177	0.000408
ORF7a	95	E95X	Gaa	Taa	28	28	AY.72	0.038095
ORF7a	95	E95X	Gaa	Taa	26	27	AY.3	0.000259
ORF7a	95	E95X	Gaa	Taa	25	25	AY.119	0.000883
ORF7a	95	E95X	Gaa	Taa	22	25	P.1	0.000347
ORF7a	95	E95X	Gaa	Taa	22	22	AY.120	0.000818
ORF7a	95	E95X	Gaa	Taa	20	20	AY.6	0.000823
ORF7a	95	E95X	Gaa	Taa	19	19	AY.26	0.000538
ORF7a	95	E95X	Gaa	Taa	19	19	AY.75	0.001064
ORF7a	95	E95X	Gaa	Taa	18	18	AY.46	0.001873
ORF7a	95	E95X	Gaa	Taa	18	18	B.1.177.61	0.782609
ORF7a	95	E95X	Gaa	Taa	16	16	B.1.1.291	0.011878
ORF7a	95	E95X	Gaa	Taa	15	15	B.1.2	0.000132
ORF7a	95	E95X	Gaa	Taa	15	15	B.1.526	0.000353
ORF7a	95	E95X	Gaa	Taa	14	14	AY.121	0.001894
ORF7a	95	E95X	Gaa	Taa	14	14	AY.46.4	0.002303
ORF7a	95	E95X	Gaa	Taa	14	14	AY.73	0.009315
ORF7a	95	E95X	Gaa	Taa	14	14	B.1.160	0.000437
ORF7a	95	E95X	Gaa	Taa	13	13	B.1.1	0.000236
ORF7a	95	E95X	Gaa	Taa	12	12	AY.23	0.000837
ORF7a	95	E95X	Gaa	Taa	12	12	B.1	0.00011
ORF7a	95	E95X	Gaa	Taa	12	12	B.1.189	0.051502
ORF7a	95	E95X	Gaa	Taa	11	11	AY.45	0.001339
ORF7a	95	E95X	Gaa	Taa	10	10	AY.98.1	0.000484
ORF7a	95	E95X	Gaa	Taa	9	9	B.1.177.81	0.001704
ORF7a	95	E95X	Gaa	Taa	9	9	B.1.319	0.027439
ORF7a	95	E95X	Gaa	Taa	8	8	AY.116	0.002294
ORF7a	95	E95X	Gaa	Taa	8	8	C.37	0.000929
ORF7a	95	E95X	Gaa	Taa	7	7	B.1.240	0.001509
ORF7a	95	E95X	Gaa	Taa	6	6	AY.20	0.000233
ORF7a	95	E95X	Gaa	Taa	6	6	AY.61	0.000629
ORF7a	95	E95X	Gaa	Taa	6	6	B.1.177.83	0.008889
ORF7a	95	E95X	Gaa	Taa	6	6	B.1.628	0.002114
ORF7a	95	E95X	Gaa	Taa	6	6	P.1.14	0.000287
ORF7a	95	E95X	Gaa	Taa	6	6	P.1.7	0.001916
ORF7a	95	E95X	Gaa	Taa	5	5	AY.117	0.000423
ORF7a	95	E95X	Gaa	Taa	5	5	AY.12	0.00158
ORF7a	95	E95X	Gaa	Taa	5	5	AY.4.2.1	0.000745
ORF7a	95	E95X	Gaa	Taa	5	5	B.1.427	0.000252
ORF7a	95	E95X	Gaa	Taa	5	5	B.1.617.1	0.000645
ORF7a	95	E95X	Gaa	Taa	5	5	D.2	0.000375
ORF7a	95	E95X	Gaa	Taa	4	4	AY.111	0.000733
ORF7a	95	E95X	Gaa	Taa	4	4	AY.113	0.00057
ORF7a	95	E95X	Gaa	Taa	4	4	AY.29	0.000063
ORF7a	95	E95X	Gaa	Taa	4	4	AY.33	0.000267
ORF7a	95	E95X	Gaa	Taa	4	4	AY.39.1	0.000158
ORF7a	95	E95X	Gaa	Taa	4	4	AY.42	0.000161
ORF7a	95	E95X	Gaa	Taa	4	4	AY.47	0.000124
ORF7a	95	E95X	Gaa	Taa	4	4	AY.5.3	0.00135
ORF7a	95	E95X	Gaa	Taa	4	4	AY.55	0.00367
ORF7a	95	E95X	Gaa	Taa	4	4	AY.7	0.000784
ORF7a	95	E95X	Gaa	Taa	4	4	AY.75.1	0.000721
ORF7a	95	E95X	Gaa	Taa	4	4	AY.98	0.000316
ORF7a	95	E95X	Gaa	Taa	4	4	B.1.1.318	0.001207
ORF7a	95	E95X	Gaa	Taa	4	4	B.1.1.519	0.000159
ORF7a	95	E95X	Gaa	Taa	4	4	B.1.177.86	0.000734
ORF7a	95	E95X	Gaa	Taa	4	4	B.1.351	0.000119
ORF7a	95	E95X	Gaa	Taa	3	3	AY.118	0.000188
ORF7a	95	E95X	Gaa	Taa	3	3	AY.27	0.000194
ORF7a	95	E95X	Gaa	Taa	3	3	AY.54	0.000286
ORF7a	95	E95X	Gaa	Taa	3	3	AY.7.2	0.001678
ORF7a	95	E95X	Gaa	Taa	3	3	AY.84	0.001312
ORF7a	95	E95X	Gaa	Taa	3	3	AY.9.1	0.000251
ORF7a	95	E95X	Gaa	Taa	3	3	B.1.177.21	0.000229
ORF7a	95	E95X	Gaa	Taa	3	3	B.1.36.8	0.003
ORF7a	95	E95X	Gaa	Taa	3	3	B.1.429	0.000071
ORF7a	95	E95X	Gaa	Taa	3	3	B.1.621	0.000266
ORF7a	95	E95X	Gaa	Taa	3	3	Q.7	0.003333
ORF7a	95	E95X	Gaa	Taa	2	2	AY.106	0.00067
ORF7a	95	E95X	Gaa	Taa	2	2	AY.109	0.001479
ORF7a	95	E95X	Gaa	Taa	2	2	AY.110	0.000225
ORF7a	95	E95X	Gaa	Taa	2	2	AY.116.1	0.000623
ORF7a	95	E95X	Gaa	Taa	2	2	AY.30	0.000791
ORF7a	95	E95X	Gaa	Taa	2	2	AY.34	0.000194
ORF7a	95	E95X	Gaa	Taa	2	2	AY.36	0.000296
ORF7a	95	E95X	Gaa	Taa	2	2	AY.46.2	0.001271
ORF7a	95	E95X	Gaa	Taa	2	2	AY.46.6	0.000144
ORF7a	95	E95X	Gaa	Taa	2	2	AY.7.1	0.000225
ORF7a	95	E95X	Gaa	Taa	2	2	AY.71	0.00095
ORF7a	95	E95X	Gaa	Taa	2	2	AY.74	0.000231
ORF7a	95	E95X	Gaa	Taa	2	2	AY.79	0.002421
ORF7a	95	E95X	Gaa	Taa	2	2	AY.87	0.001665
ORF7a	95	E95X	Gaa	Taa	2	2	B.1.1.192	0.004619
ORF7a	95	E95X	Gaa	Taa	2	2	B.1.1.200	0.014925
ORF7a	95	E95X	Gaa	Taa	2	2	B.1.1.316	0.00185
ORF7a	95	E95X	Gaa	Taa	2	2	B.1.177.16	0.001329
ORF7a	95	E95X	Gaa	Taa	2	2	B.1.324	0.00321
ORF7a	95	E95X	Gaa	Taa	2	2	B.1.350	0.005865
ORF7a	95	E95X	Gaa	Taa	2	2	B.1.351.2	0.000605
ORF7a	95	E95X	Gaa	Taa	2	2	B.1.596	0.000174
ORF7a	95	E95X	Gaa	Taa	2	2	P.2	0.000373
ORF7a	95	E95X	Gaa	Taa	2	2	Q.1	0.000253
ORF7a	95	E95X	Gaa	Taa	2	2	Q.8	0.00033
ORF7a	95	E95X	Gaa	Taa	1	1	A	0.000387
ORF7a	95	E95X	Gaa	Taa	1	1	A.2.4	0.003367
ORF7a	95	E95X	Gaa	Taa	1	1	AY.101	0.00049
ORF7a	95	E95X	Gaa	Taa	1	1	AY.105	0.000643
ORF7a	95	E95X	Gaa	Taa	1	1	AY.120.1	0.000321
ORF7a	95	E95X	Gaa	Taa	1	1	AY.3.1	0.000085
ORF7a	95	E95X	Gaa	Taa	1	1	AY.32	0.000532
ORF7a	95	E95X	Gaa	Taa	1	1	AY.37	0.000316
ORF7a	95	E95X	Gaa	Taa	1	1	AY.4.2	0.000022
ORF7a	95	E95X	Gaa	Taa	1	1	AY.4.4	0.000409
ORF7a	95	E95X	Gaa	Taa	1	1	AY.46.3	0.000934
ORF7a	95	E95X	Gaa	Taa	1	1	AY.52	0.000814
ORF7a	95	E95X	Gaa	Taa	1	1	AY.56	0.001605
ORF7a	95	E95X	Gaa	Taa	1	1	AY.65	0.000533
ORF7a	95	E95X	Gaa	Taa	1	1	AY.69	0.000187
ORF7a	95	E95X	Gaa	Taa	1	1	AY.8	0.000606
ORF7a	95	E95X	Gaa	Taa	1	1	AY.88	0.000884
ORF7a	95	E95X	Gaa	Taa	1	1	AY.89	0.004902
ORF7a	95	E95X	Gaa	Taa	1	1	AY.9	0.000068
ORF7a	95	E95X	Gaa	Taa	1	1	AY.92	0.000287
ORF7a	95	E95X	Gaa	Taa	1	1	AY.99	0.001049
ORF7a	95	E95X	Gaa	Taa	1	1	AY.99.2	0.000092
ORF7a	95	E95X	Gaa	Taa	1	1	B	0.000128
ORF7a	95	E95X	Gaa	Taa	1	1	B.1.1.1	0.000327
ORF7a	95	E95X	Gaa	Taa	1	1	B.1.1.216	0.00089
ORF7a	95	E95X	Gaa	Taa	1	1	B.1.1.272	0.005208
ORF7a	95	E95X	Gaa	Taa	1	1	B.1.1.28	0.000311
ORF7a	95	E95X	Gaa	Taa	1	1	B.1.1.303	0.002762
ORF7a	95	E95X	Gaa	Taa	1	1	B.1.1.406	0.006494
ORF7a	95	E95X	Gaa	Taa	1	1	B.1.177.42	0.000894
ORF7a	95	E95X	Gaa	Taa	1	1	B.1.177.60	0.000218
ORF7a	95	E95X	Gaa	Taa	1	1	B.1.177.7	0.000165
ORF7a	95	E95X	Gaa	Taa	1	1	B.1.258.9	0.005
ORF7a	95	E95X	Gaa	Taa	1	1	B.1.301	0.005917
ORF7a	95	E95X	Gaa	Taa	1	1	B.1.338	0.008621
ORF7a	95	E95X	Gaa	Taa	1	1	B.1.340	0.004292
ORF7a	95	E95X	Gaa	Taa	1	1	B.1.351.3	0.000876
ORF7a	95	E95X	Gaa	Taa	1	1	B.1.36	0.000146
ORF7a	95	E95X	Gaa	Taa	1	1	B.1.467	0.04
ORF7a	95	E95X	Gaa	Taa	1	1	B.1.497	0.000315
ORF7a	95	E95X	Gaa	Taa	1	1	B.1.525	0.000113
ORF7a	95	E95X	Gaa	Taa	1	1	B.1.556	0.007519
ORF7a	95	E95X	Gaa	Taa	1	1	B.1.582	0.000491
ORF7a	95	E95X	Gaa	Taa	1	1	B.1.595	0.000261
ORF7a	95	E95X	Gaa	Taa	1	1	B.1.609	0.000479
ORF7a	95	E95X	Gaa	Taa	1	1	B.1.621.1	0.000506
ORF7a	95	E95X	Gaa	Taa	1	1	B.1.623	0.000536
ORF7a	95	E95X	Gaa	Taa	1	1	B.1.637	0.000073
ORF7a	95	E95X	Gaa	Taa	1	1	B.40	0.000364
ORF7a	95	E95X	Gaa	Taa	1	1	P.1.17.1	0.000875
ORF7a	95	E95X	Gaa	Taa	1	1	Q.3	0.000145
ORF7a	95	E95X	Gaa	Taa	1	1	Q.4	0.000455

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.