CoV-GLUE Mutation

CoV-GLUE Mutation: ORF = ORF7a : CodonNum = 79 & Codon = gcT

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORF	CodonNum	Mut	ORF1abMut	MutType	RefCodon	MutCodon	AACount	CodonCount	CodonProp	Genome Position
ORF7a	79	A79A		syn	gcC	gcT	7972	6849	0.859132	27628-27630

Details of the mutation no within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORF	CodonNum	Mut	RefCodon	MutCodon	CodonCount	AACount	Lineage	LineageCodonProp
ORF7a	79	A79A	gcC	gcT	6849	7972	All	0.00131
ORF7a	79	A79A	gcC	gcT	1710	1877	B.1.1.7	0.001531
ORF7a	79	A79A	gcC	gcT	720	781	AY.4	0.001121
ORF7a	79	A79A	gcC	gcT	562	562	B.1.1.486	0.886435
ORF7a	79	A79A	gcC	gcT	226	441	B.1.526	0.005312
ORF7a	79	A79A	gcC	gcT	194	366	B.1.2	0.001708
ORF7a	79	A79A	gcC	gcT	347	348	B.1.1.214	0.019244
ORF7a	79	A79A	gcC	gcT	261	307	B.1.617.2	0.000983
ORF7a	79	A79A	gcC	gcT	239	263	B.1.429	0.005623
ORF7a	79	A79A	gcC	gcT	198	203	AY.43	0.000877
ORF7a	79	A79A	gcC	gcT	123	179	AY.103	0.000764
ORF7a	79	A79A	gcC	gcT	123	128	AY.3	0.001223
ORF7a	79	A79A	gcC	gcT	111	114	AY.47	0.003453
ORF7a	79	A79A	gcC	gcT	101	108	B.1	0.000925
ORF7a	79	A79A	gcC	gcT	98	101	B.1.243	0.006819
ORF7a	79	A79A	gcC	gcT	79	91	B.1.1	0.001433
ORF7a	79	A79A	gcC	gcT	75	90	P.1	0.001182
ORF7a	79	A79A	gcC	gcT	72	85	AY.39	0.001779
ORF7a	79	A79A	gcC	gcT	82	82	A.2.5	0.040918
ORF7a	79	A79A	gcC	gcT	10	66	P.1.14	0.000478
ORF7a	79	A79A	gcC	gcT	42	65	AY.25	0.000253
ORF7a	79	A79A	gcC	gcT	65	65	P.2	0.012131
ORF7a	79	A79A	gcC	gcT	10	61	AY.44	0.000061
ORF7a	79	A79A	gcC	gcT	56	58	AY.102	0.001485
ORF7a	79	A79A	gcC	gcT	13	51	AY.100	0.000598
ORF7a	79	A79A	gcC	gcT	46	50	B.1.351	0.001367
ORF7a	79	A79A	gcC	gcT	38	40	B.1.177	0.0005
ORF7a	79	A79A	gcC	gcT	36	36	B.1.558	0.164384
ORF7a	79	A79A	gcC	gcT	35	35	B.1.371	0.039282
ORF7a	79	A79A	gcC	gcT	22	33	AY.26	0.000623
ORF7a	79	A79A	gcC	gcT	28	32	B.1.160	0.000873
ORF7a	79	A79A	gcC	gcT	30	30	B.1.609	0.014382
ORF7a	79	A79A	gcC	gcT	22	27	AY.4.2	0.000477
ORF7a	79	A79A	gcC	gcT	27	27	B.1.1.434	0.009411
ORF7a	79	A79A	gcC	gcT	21	24	AY.118	0.001316
ORF7a	79	A79A	gcC	gcT	22	24	B.1.595	0.005741
ORF7a	79	A79A	gcC	gcT	23	23	B.1.1.275	0.258427
ORF7a	79	A79A	gcC	gcT	23	23	B.1.637	0.001681
ORF7a	79	A79A	gcC	gcT	22	22	P.1.15	0.005112
ORF7a	79	A79A	gcC	gcT	18	21	AY.68	0.004927
ORF7a	79	A79A	gcC	gcT	17	21	B.1.1.519	0.000675
ORF7a	79	A79A	gcC	gcT	20	20	AY.75	0.00112
ORF7a	79	A79A	gcC	gcT	19	19	B.1.177.75	0.019771
ORF7a	79	A79A	gcC	gcT	19	19	B.1.241	0.015422
ORF7a	79	A79A	gcC	gcT	19	19	B.1.427	0.000959
ORF7a	79	A79A	gcC	gcT	15	17	AY.20	0.000583
ORF7a	79	A79A	gcC	gcT	17	17	AY.67	0.007892
ORF7a	79	A79A	gcC	gcT	17	17	B.1.1.141	0.034205
ORF7a	79	A79A	gcC	gcT	12	17	B.1.258	0.000799
ORF7a	79	A79A	gcC	gcT	13	16	B.1.36	0.001897
ORF7a	79	A79A	gcC	gcT	16	16	B.1.369	0.004564
ORF7a	79	A79A	gcC	gcT	14	15	AY.119	0.000494
ORF7a	79	A79A	gcC	gcT	13	14	AY.29	0.000205
ORF7a	79	A79A	gcC	gcT	14	14	B.1.1.192	0.032333
ORF7a	79	A79A	gcC	gcT	10	14	B.1.1.33	0.004209
ORF7a	79	A79A	gcC	gcT	12	13	AY.5	0.000248
ORF7a	79	A79A	gcC	gcT	6	12	AY.120	0.000223
ORF7a	79	A79A	gcC	gcT	12	12	AY.4.2.1	0.001788
ORF7a	79	A79A	gcC	gcT	8	12	AY.42	0.000322
ORF7a	79	A79A	gcC	gcT	12	12	B.1.1.39	0.006116
ORF7a	79	A79A	gcC	gcT	12	12	B.1.1.70	0.004093
ORF7a	79	A79A	gcC	gcT	11	11	B.1.541	0.048673
ORF7a	79	A79A	gcC	gcT	5	10	AY.33	0.000334
ORF7a	79	A79A	gcC	gcT	8	10	AY.54	0.000763
ORF7a	79	A79A	gcC	gcT	10	10	AY.98	0.00079
ORF7a	79	A79A	gcC	gcT	10	10	B.1.1.348	0.007962
ORF7a	79	A79A	gcC	gcT	7	10	C.37	0.000812
ORF7a	79	A79A	gcC	gcT	8	9	AY.4.5	0.00086
ORF7a	79	A79A	gcC	gcT	8	9	AY.46.6	0.000578
ORF7a	79	A79A	gcC	gcT	9	9	AY.69	0.00168
ORF7a	79	A79A	gcC	gcT	7	9	AY.9.2	0.000257
ORF7a	79	A79A	gcC	gcT	9	9	B.1.1.402	0.1
ORF7a	79	A79A	gcC	gcT	9	9	B.1.1.50	0.00611
ORF7a	79	A79A	gcC	gcT	9	9	B.1.239	0.010989
ORF7a	79	A79A	gcC	gcT	9	9	B.1.551	0.011613
ORF7a	79	A79A	gcC	gcT	8	9	B.1.596	0.000697
ORF7a	79	A79A	gcC	gcT	7	8	AY.3.1	0.000597
ORF7a	79	A79A	gcC	gcT	8	8	AY.34	0.000776
ORF7a	79	A79A	gcC	gcT	8	8	AY.61	0.000838
ORF7a	79	A79A	gcC	gcT	8	8	B.1.1.311	0.002865
ORF7a	79	A79A	gcC	gcT	8	8	B.1.396	0.005646
ORF7a	79	A79A	gcC	gcT	8	8	B.1.561	0.003176
ORF7a	79	A79A	gcC	gcT	4	8	B.1.621	0.000354
ORF7a	79	A79A	gcC	gcT	7	7	AY.121	0.000947
ORF7a	79	A79A	gcC	gcT	7	7	AY.14	0.000616
ORF7a	79	A79A	gcC	gcT	7	7	AY.46	0.000729
ORF7a	79	A79A	gcC	gcT	7	7	AY.5.3	0.002362
ORF7a	79	A79A	gcC	gcT	7	7	B.1.1.222	0.001428
ORF7a	79	A79A	gcC	gcT	7	7	B.1.1.224	0.1
ORF7a	79	A79A	gcC	gcT	7	7	B.1.1.284	0.000752
ORF7a	79	A79A	gcC	gcT	6	7	B.1.177.82	0.002864
ORF7a	79	A79A	gcC	gcT	6	6	AY.23	0.000418
ORF7a	79	A79A	gcC	gcT	6	6	AY.39.1	0.000238
ORF7a	79	A79A	gcC	gcT	5	6	B.1.1.28	0.001556
ORF7a	79	A79A	gcC	gcT	6	6	B.1.499	0.006303
ORF7a	79	A79A	gcC	gcT	6	6	B.1.562	0.111111
ORF7a	79	A79A	gcC	gcT	6	6	C.36	0.005464
ORF7a	79	A79A	gcC	gcT	5	6	P.1.7	0.001596
ORF7a	79	A79A	gcC	gcT	5	5	B.1.1.25	0.002843
ORF7a	79	A79A	gcC	gcT	5	5	B.1.1.294	0.006329
ORF7a	79	A79A	gcC	gcT	5	5	B.1.1.316	0.004625
ORF7a	79	A79A	gcC	gcT	5	5	B.1.1.38	0.294118
ORF7a	79	A79A	gcC	gcT	5	5	B.1.177.10	0.00439
ORF7a	79	A79A	gcC	gcT	5	5	B.1.177.12	0.000758
ORF7a	79	A79A	gcC	gcT	4	5	B.1.221	0.000284
ORF7a	79	A79A	gcC	gcT	5	5	B.1.346	0.006553
ORF7a	79	A79A	gcC	gcT	3	5	B.1.525	0.000339
ORF7a	79	A79A	gcC	gcT	5	5	C.16	0.005302
ORF7a	79	A79A	gcC	gcT	5	5	C.36.3	0.002836
ORF7a	79	A79A	gcC	gcT	5	5	Q.4	0.002274
ORF7a	79	A79A	gcC	gcT	3	4	AY.113	0.000427
ORF7a	79	A79A	gcC	gcT	4	4	AY.29.1	0.000882
ORF7a	79	A79A	gcC	gcT	3	4	AY.45	0.000365
ORF7a	79	A79A	gcC	gcT	4	4	AY.62	0.001743
ORF7a	79	A79A	gcC	gcT	4	4	AY.66	0.004278
ORF7a	79	A79A	gcC	gcT	2	4	AY.75.1	0.000361
ORF7a	79	A79A	gcC	gcT	4	4	AY.99.2	0.000369
ORF7a	79	A79A	gcC	gcT	4	4	B.1.1.412	0.030534
ORF7a	79	A79A	gcC	gcT	4	4	B.1.1.58	0.021505
ORF7a	79	A79A	gcC	gcT	4	4	B.1.177.7	0.000659
ORF7a	79	A79A	gcC	gcT	4	4	B.1.177.73	0.002265
ORF7a	79	A79A	gcC	gcT	4	4	B.1.177.81	0.000757
ORF7a	79	A79A	gcC	gcT	4	4	B.1.177.86	0.000734
ORF7a	79	A79A	gcC	gcT	4	4	B.1.351.2	0.00121
ORF7a	79	A79A	gcC	gcT	3	4	B.1.351.3	0.002629
ORF7a	79	A79A	gcC	gcT	4	4	B.1.36.29	0.002069
ORF7a	79	A79A	gcC	gcT	4	4	B.1.617.1	0.000516
ORF7a	79	A79A	gcC	gcT	4	4	Q.2	0.002454
ORF7a	79	A79A	gcC	gcT	4	4	Q.3	0.00058
ORF7a	79	A79A	gcC	gcT	3	3	AY.116	0.00086
ORF7a	79	A79A	gcC	gcT	3	3	AY.24	0.001293
ORF7a	79	A79A	gcC	gcT	2	3	AY.27	0.000129
ORF7a	79	A79A	gcC	gcT	3	3	AY.64	0.001786
ORF7a	79	A79A	gcC	gcT	3	3	AY.85	0.001282
ORF7a	79	A79A	gcC	gcT	2	3	AY.9	0.000135
ORF7a	79	A79A	gcC	gcT	2	3	AY.98.1	0.000097
ORF7a	79	A79A	gcC	gcT	2	3	B	0.000256
ORF7a	79	A79A	gcC	gcT	3	3	B.1.1.135	0.014085
ORF7a	79	A79A	gcC	gcT	3	3	B.1.1.416	0.002715
ORF7a	79	A79A	gcC	gcT	3	3	B.1.160.30	0.008929
ORF7a	79	A79A	gcC	gcT	2	3	B.1.177.21	0.000153
ORF7a	79	A79A	gcC	gcT	3	3	B.1.177.60	0.000655
ORF7a	79	A79A	gcC	gcT	3	3	B.1.177.87	0.002183
ORF7a	79	A79A	gcC	gcT	3	3	B.1.36.18	0.001261
ORF7a	79	A79A	gcC	gcT	3	3	B.1.367	0.002377
ORF7a	79	A79A	gcC	gcT	3	3	B.1.438.1	0.000322
ORF7a	79	A79A	gcC	gcT	1	3	B.1.576	0.000907
ORF7a	79	A79A	gcC	gcT	3	3	B.1.581	0.028302
ORF7a	79	A79A	gcC	gcT	3	3	C.35	0.002322
ORF7a	79	A79A	gcC	gcT	3	3	Q.6	0.019868
ORF7a	79	A79A	gcC	gcT	3	3	Q.8	0.000495
ORF7a	79	A79A	gcC	gcT	2	3	R.1	0.00018
ORF7a	79	A79A	gcC	gcT	2	2	A.23.1	0.001408
ORF7a	79	A79A	gcC	gcT	2	2	AD.2	0.000438
ORF7a	79	A79A	gcC	gcT	2	2	AY.10	0.00106
ORF7a	79	A79A	gcC	gcT	2	2	AY.106	0.00067
ORF7a	79	A79A	gcC	gcT	2	2	AY.116.1	0.000623
ORF7a	79	A79A	gcC	gcT	2	2	AY.23.1	0.000835
ORF7a	79	A79A	gcC	gcT	2	2	AY.32	0.001065
ORF7a	79	A79A	gcC	gcT	2	2	AY.46.2	0.001271
ORF7a	79	A79A	gcC	gcT	2	2	AY.63	0.000774
ORF7a	79	A79A	gcC	gcT	1	2	AY.77	0.001127
ORF7a	79	A79A	gcC	gcT	2	2	AY.87	0.001665
ORF7a	79	A79A	gcC	gcT	2	2	B.1.1.10	0.00223
ORF7a	79	A79A	gcC	gcT	2	2	B.1.1.253	0.005013
ORF7a	79	A79A	gcC	gcT	2	2	B.1.1.269	0.002706
ORF7a	79	A79A	gcC	gcT	2	2	B.1.1.306	0.000877
ORF7a	79	A79A	gcC	gcT	2	2	B.1.1.389	0.012121
ORF7a	79	A79A	gcC	gcT	2	2	B.1.1.407	0.083333
ORF7a	79	A79A	gcC	gcT	2	2	B.1.1.464	0.002946
ORF7a	79	A79A	gcC	gcT	2	2	B.1.1.72	0.060606
ORF7a	79	A79A	gcC	gcT	2	2	B.1.177.23	0.006472
ORF7a	79	A79A	gcC	gcT	2	2	B.1.177.4	0.000422
ORF7a	79	A79A	gcC	gcT	2	2	B.1.177.55	0.004662
ORF7a	79	A79A	gcC	gcT	2	2	B.1.177.57	0.000562
ORF7a	79	A79A	gcC	gcT	1	2	B.1.206	0.000816
ORF7a	79	A79A	gcC	gcT	2	2	B.1.258.11	0.000793
ORF7a	79	A79A	gcC	gcT	2	2	B.1.258.14	0.001961
ORF7a	79	A79A	gcC	gcT	2	2	B.1.258.17	0.000208
ORF7a	79	A79A	gcC	gcT	2	2	B.1.320	0.002491
ORF7a	79	A79A	gcC	gcT	2	2	B.1.336	0.004878
ORF7a	79	A79A	gcC	gcT	2	2	B.1.349	0.00143
ORF7a	79	A79A	gcC	gcT	2	2	B.1.36.38	0.003284
ORF7a	79	A79A	gcC	gcT	2	2	B.1.416.1	0.003125
ORF7a	79	A79A	gcC	gcT	2	2	B.1.466.2	0.000782
ORF7a	79	A79A	gcC	gcT	2	2	B.1.517	0.000854
ORF7a	79	A79A	gcC	gcT	2	2	B.1.564	0.000852
ORF7a	79	A79A	gcC	gcT	1	2	D.2	0.000075
ORF7a	79	A79A	gcC	gcT	2	2	P.1.12	0.000968
ORF7a	79	A79A	gcC	gcT	2	2	P.1.17	0.000324
ORF7a	79	A79A	gcC	gcT	2	2	P.1.9	0.009615
ORF7a	79	A79A	gcC	gcT	2	2	Q.1	0.000253
ORF7a	79	A79A	gcC	gcT	1	1	A	0.000387
ORF7a	79	A79A	gcC	gcT	1	1	A.19	0.009434
ORF7a	79	A79A	gcC	gcT	1	1	A.2	0.000662
ORF7a	79	A79A	gcC	gcT	1	1	A.28	0.002646
ORF7a	79	A79A	gcC	gcT	1	1	AP.1	0.001502
ORF7a	79	A79A	gcC	gcT	1	1	AY.101	0.00049
ORF7a	79	A79A	gcC	gcT	1	1	AY.104	0.001984
ORF7a	79	A79A	gcC	gcT	1	1	AY.107	0.000466
ORF7a	79	A79A	gcC	gcT	1	1	AY.109	0.00074
ORF7a	79	A79A	gcC	gcT	1	1	AY.110	0.000113
ORF7a	79	A79A	gcC	gcT	1	1	AY.13	0.000161
ORF7a	79	A79A	gcC	gcT	1	1	AY.16	0.00038
ORF7a	79	A79A	gcC	gcT	1	1	AY.30	0.000396
ORF7a	79	A79A	gcC	gcT	1	1	AY.36	0.000148
ORF7a	79	A79A	gcC	gcT	1	1	AY.37	0.000316
ORF7a	79	A79A	gcC	gcT	1	1	AY.38	0.000499
ORF7a	79	A79A	gcC	gcT	1	1	AY.46.4	0.000165
ORF7a	79	A79A	gcC	gcT	1	1	AY.5.1	0.003759
ORF7a	79	A79A	gcC	gcT	1	1	AY.5.4	0.000277
ORF7a	79	A79A	gcC	gcT	1	1	AY.53	0.000288
ORF7a	79	A79A	gcC	gcT	1	1	AY.6	0.000041
ORF7a	79	A79A	gcC	gcT	1	1	AY.65	0.000533
ORF7a	79	A79A	gcC	gcT	1	1	AY.78	0.001541
ORF7a	79	A79A	gcC	gcT	1	1	AY.79	0.001211
ORF7a	79	A79A	gcC	gcT	1	1	AY.86	0.00083
ORF7a	79	A79A	gcC	gcT	1	1	AY.9.1	0.000084
ORF7a	79	A79A	gcC	gcT	1	1	AY.91	0.00073
ORF7a	79	A79A	gcC	gcT	1	1	AY.94	0.000443
ORF7a	79	A79A	gcC	gcT	1	1	AZ.1	0.000867
ORF7a	79	A79A	gcC	gcT	1	1	B.1.1.153	0.001095
ORF7a	79	A79A	gcC	gcT	1	1	B.1.1.196	0.005714
ORF7a	79	A79A	gcC	gcT	1	1	B.1.1.198	0.001468
ORF7a	79	A79A	gcC	gcT	1	1	B.1.1.216	0.00089
ORF7a	79	A79A	gcC	gcT	1	1	B.1.1.219	0.005
ORF7a	79	A79A	gcC	gcT	1	1	B.1.1.258	0.003257
ORF7a	79	A79A	gcC	gcT	1	1	B.1.1.272	0.005208
ORF7a	79	A79A	gcC	gcT	1	1	B.1.1.302	0.002075
ORF7a	79	A79A	gcC	gcT	1	1	B.1.1.309	0.005848
ORF7a	79	A79A	gcC	gcT	1	1	B.1.1.312	0.001912
ORF7a	79	A79A	gcC	gcT	1	1	B.1.1.315	0.008475
ORF7a	79	A79A	gcC	gcT	1	1	B.1.1.318	0.000302
ORF7a	79	A79A	gcC	gcT	1	1	B.1.1.326	0.001761
ORF7a	79	A79A	gcC	gcT	1	1	B.1.1.344	0.010753
ORF7a	79	A79A	gcC	gcT	1	1	B.1.1.372	0.000689
ORF7a	79	A79A	gcC	gcT	1	1	B.1.1.404	0.015873
ORF7a	79	A79A	gcC	gcT	1	1	B.1.1.525	0.005464
ORF7a	79	A79A	gcC	gcT	1	1	B.1.1.54	0.003021
ORF7a	79	A79A	gcC	gcT	1	1	B.1.1.63	0.000386
ORF7a	79	A79A	gcC	gcT	1	1	B.1.177.20	0.001517
ORF7a	79	A79A	gcC	gcT	1	1	B.1.177.5	0.001242
ORF7a	79	A79A	gcC	gcT	1	1	B.1.177.62	0.001192
ORF7a	79	A79A	gcC	gcT	1	1	B.1.177.77	0.000726
ORF7a	79	A79A	gcC	gcT	1	1	B.1.221.2	0.004016
ORF7a	79	A79A	gcC	gcT	1	1	B.1.23	0.006061
ORF7a	79	A79A	gcC	gcT	1	1	B.1.236	0.002053
ORF7a	79	A79A	gcC	gcT	1	1	B.1.3	0.002618
ORF7a	79	A79A	gcC	gcT	1	1	B.1.311	0.000275
ORF7a	79	A79A	gcC	gcT	1	1	B.1.333	0.010526
ORF7a	79	A79A	gcC	gcT	1	1	B.1.36.16	0.001425
ORF7a	79	A79A	gcC	gcT	1	1	B.1.36.24	0.006173
ORF7a	79	A79A	gcC	gcT	1	1	B.1.362	0.001541
ORF7a	79	A79A	gcC	gcT	1	1	B.1.380	0.006623
ORF7a	79	A79A	gcC	gcT	1	1	B.1.395	0.007042
ORF7a	79	A79A	gcC	gcT	1	1	B.1.400	0.000429
ORF7a	79	A79A	gcC	gcT	1	1	B.1.409	0.000781
ORF7a	79	A79A	gcC	gcT	1	1	B.1.422	0.000812
ORF7a	79	A79A	gcC	gcT	1	1	B.1.446	0.02
ORF7a	79	A79A	gcC	gcT	1	1	B.1.456	0.003268
ORF7a	79	A79A	gcC	gcT	1	1	B.1.498	0.020408
ORF7a	79	A79A	gcC	gcT	1	1	B.1.509	0.000866
ORF7a	79	A79A	gcC	gcT	1	1	B.1.524	0.001406
ORF7a	79	A79A	gcC	gcT	1	1	B.1.540	0.009709
ORF7a	79	A79A	gcC	gcT	1	1	B.1.560	0.00463
ORF7a	79	A79A	gcC	gcT	1	1	B.1.580	0.004065
ORF7a	79	A79A	gcC	gcT	1	1	B.1.585	0.027778
ORF7a	79	A79A	gcC	gcT	1	1	B.1.588	0.00091
ORF7a	79	A79A	gcC	gcT	1	1	B.1.598	0.016949
ORF7a	79	A79A	gcC	gcT	1	1	B.1.93	0.000934
ORF7a	79	A79A	gcC	gcT	1	1	B.40	0.000364
ORF7a	79	A79A	gcC	gcT	1	1	B.6	0.00091
ORF7a	79	A79A	gcC	gcT	1	1	C.1	0.002392
ORF7a	79	A79A	gcC	gcT	1	1	C.1.2	0.004255
ORF7a	79	A79A	gcC	gcT	1	1	U.3	0.003861

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.