CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF6 : Mut = M19I

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF619M19InonsynatGatT5233720.71128127256-27258
ORF619M19InonsynatGatA5231500.28680727256-27258
ORF619M19InonsynatGatC52310.0019120527256-27258

Details of the mutation M19I within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF619M19IatGatT372523All0.000071
ORF619M19IatGatA150523All0.000029
ORF619M19IatGatC1523All0
ORF619M19IatGatT162162B.1.6050.964286
ORF619M19IatGatA98111B.1.1.70.000088
ORF619M19IatGatT12111B.1.1.70.000011
ORF619M19IatGatC1111B.1.1.70.000001
ORF619M19IatGatT2831AY.30.000278
ORF619M19IatGatA331AY.30.00003
ORF619M19IatGatT2121B.10.000192
ORF619M19IatGatA1515B.1.1770.000198
ORF619M19IatGatT1414B.1.2790.007191
ORF619M19IatGatT1313B.1.20.000114
ORF619M19IatGatT1011AY.430.000044
ORF619M19IatGatA111AY.430.000004
ORF619M19IatGatT1010AY.1160.002868
ORF619M19IatGatT610AY.40.000009
ORF619M19IatGatA410AY.40.000006
ORF619M19IatGatT69B.1.617.20.000023
ORF619M19IatGatA39B.1.617.20.000011
ORF619M19IatGatT68AY.1030.000037
ORF619M19IatGatA28AY.1030.000012
ORF619M19IatGatA77AY.200.000272
ORF619M19IatGatT77AY.250.000042
ORF619M19IatGatT66B.1.4270.000303
ORF619M19IatGatT66B.1.5250.000679
ORF619M19IatGatT55B.1.5260.000118
ORF619M19IatGatT44B.1.177.320.005398
ORF619M19IatGatT44B.1.177.860.000734
ORF619M19IatGatT44B.1.5580.018265
ORF619M19IatGatT33AY.1130.000427
ORF619M19IatGatT33AY.360.000445
ORF619M19IatGatT23B.1.10.000036
ORF619M19IatGatA13B.1.10.000018
ORF619M19IatGatA33B.1.1.5190.000119
ORF619M19IatGatA12AY.1020.000027
ORF619M19IatGatT12AY.1020.000027
ORF619M19IatGatT22AY.50.000041
ORF619M19IatGatT22AY.540.000191
ORF619M19IatGatT22AY.90.000135
ORF619M19IatGatT22AY.99.20.000184
ORF619M19IatGatA12B.1.3690.000285
ORF619M19IatGatT12B.1.3690.000285
ORF619M19IatGatT22B.1.5160.003914
ORF619M19IatGatT22B.1.5950.000522
ORF619M19IatGatT22D.20.00015
ORF619M19IatGatT11AY.1190.000035
ORF619M19IatGatT11AY.120.000316
ORF619M19IatGatA11AY.120.10.000321
ORF619M19IatGatT11AY.1210.000135
ORF619M19IatGatA11AY.160.00038
ORF619M19IatGatT11AY.230.00007
ORF619M19IatGatA11AY.240.000431
ORF619M19IatGatA11AY.330.000067
ORF619M19IatGatT11AY.390.000025
ORF619M19IatGatT11AY.39.10.00004
ORF619M19IatGatT11AY.46.40.000165
ORF619M19IatGatT11AY.5.40.000277
ORF619M19IatGatT11AY.60.000041
ORF619M19IatGatT11AY.680.000274
ORF619M19IatGatT11AY.690.000187
ORF619M19IatGatA11B.1.1.2040.00304
ORF619M19IatGatT11B.1.1.2440.015385
ORF619M19IatGatT11B.1.1.2910.000742
ORF619M19IatGatT11B.1.1.330.000421
ORF619M19IatGatA11B.1.1.370.000193
ORF619M19IatGatA11B.1.1.4340.000349
ORF619M19IatGatT11B.1.177.540.000606
ORF619M19IatGatA11B.1.177.560.000668
ORF619M19IatGatT11B.1.177.70.000165
ORF619M19IatGatT11B.1.177.750.001041
ORF619M19IatGatA11B.1.2080.04
ORF619M19IatGatT11B.1.3510.00003
ORF619M19IatGatT11B.1.3980.002976
ORF619M19IatGatA11B.1.617.10.000129
ORF619M19IatGatT11B.1.6230.000536
ORF619M19IatGatT11B.280.003279
ORF619M19IatGatT11B.460.020833
ORF619M19IatGatA11P.10.000016
ORF619M19IatGatT11P.1.140.000048
ORF619M19IatGatT11P.1.20.001156

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.