CoV-GLUE Mutation

CoV-GLUE Mutation: ORF = ORF6 : Mut = D61del1

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORF	CodonNum	Mut	ORF1abMut	MutType	RefCodon	MutCodon	AACount	CodonCount	CodonProp	Genome Position
ORF6	61	D61del1		del	Gat	-at	147	104	0.707483	27382-27384
ORF6	61	D61del1		del	gaT	ga-	147	35	0.238095	27382-27384
ORF6	61	D61del1		del	gAt	g-t	147	3	0.0204082	27382-27384
ORF6	61	D61del1		del	gAT	g-N	147	2	0.0136054	27382-27384
ORF6	61	D61del1		del	GAt	-Ct	147	2	0.0136054	27382-27384
ORF6	61	D61del1		del	GAT	-TN	147	1	0.00680272	27382-27384

Details of the mutation D61del1 within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORF	CodonNum	Mut	RefCodon	MutCodon	CodonCount	AACount	Lineage	LineageCodonProp
ORF6	61	D61del1	Gat	-at	104	147	All	0.00002
ORF6	61	D61del1	gaT	ga-	35	147	All	0.000007
ORF6	61	D61del1	gAt	g-t	3	147	All	0.000001
ORF6	61	D61del1	gAT	g-N	2	147	All	0
ORF6	61	D61del1	GAt	-Ct	2	147	All	0
ORF6	61	D61del1	GAT	-TN	1	147	All	0
ORF6	61	D61del1	Gat	-at	83	83	B.1.214.2	0.04976
ORF6	61	D61del1	Gat	-at	11	20	B.1.1.7	0.00001
ORF6	61	D61del1	gaT	ga-	7	20	B.1.1.7	0.000006
ORF6	61	D61del1	GAt	-Ct	2	20	B.1.1.7	0.000002
ORF6	61	D61del1	gaT	ga-	9	9	A.27	0.014901
ORF6	61	D61del1	gaT	ga-	3	3	AY.47	0.000093
ORF6	61	D61del1	gaT	ga-	2	3	B.1.1	0.000036
ORF6	61	D61del1	Gat	-at	1	3	B.1.1	0.000018
ORF6	61	D61del1	Gat	-at	2	2	AY.4	0.000003
ORF6	61	D61del1	Gat	-at	1	2	AY.43	0.000004
ORF6	61	D61del1	gAt	g-t	1	2	AY.43	0.000004
ORF6	61	D61del1	gaT	ga-	1	2	B.1	0.000009
ORF6	61	D61del1	Gat	-at	1	2	B.1	0.000009
ORF6	61	D61del1	gaT	ga-	1	2	B.1.2	0.000009
ORF6	61	D61del1	GAT	-TN	1	2	B.1.2	0.000009
ORF6	61	D61del1	Gat	-at	2	2	B.1.214	0.007326
ORF6	61	D61del1	gaT	ga-	1	2	B.1.240	0.000216
ORF6	61	D61del1	Gat	-at	1	2	B.1.240	0.000216
ORF6	61	D61del1	gAT	g-N	2	2	B.1.617.2	0.000008
ORF6	61	D61del1	gaT	ga-	2	2	B.1.617.3	0.00597
ORF6	61	D61del1	Gat	-at	1	1	AY.101	0.00049
ORF6	61	D61del1	gaT	ga-	1	1	AY.16	0.00038
ORF6	61	D61del1	gaT	ga-	1	1	AY.25	0.000006
ORF6	61	D61del1	gaT	ga-	1	1	AY.7.2	0.000559
ORF6	61	D61del1	gAt	g-t	1	1	AY.75.1	0.00018
ORF6	61	D61del1	gaT	ga-	1	1	AY.82	0.001357
ORF6	61	D61del1	gaT	ga-	1	1	AY.9.2	0.000037
ORF6	61	D61del1	gaT	ga-	1	1	B.1.1.207	0.001182
ORF6	61	D61del1	gaT	ga-	1	1	B.1.1.33	0.000421
ORF6	61	D61del1	Gat	-at	1	1	B.1.214.1	0.02
ORF6	61	D61del1	gaT	ga-	1	1	B.1.247	0.014925
ORF6	61	D61del1	gaT	ga-	1	1	B.1.427	0.00005
ORF6	61	D61del1	gAt	g-t	1	1	B.1.617.1	0.000129

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.