CoV-GLUE Mutation

CoV-GLUE Mutation: ORF = ORF6 : CodonNum = 61 & Codon = Cat

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORF	CodonNum	Mut	ORF1abMut	MutType	RefCodon	MutCodon	AACount	CodonCount	CodonProp	Genome Position
ORF6	61	D61H		nonsyn	Gat	Cat	1473	1362	0.924644	27382-27384

Details of the mutation no within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORF	CodonNum	Mut	RefCodon	MutCodon	CodonCount	AACount	Lineage	LineageCodonProp
ORF6	61	D61H	Gat	Cat	1362	1473	All	0.00026
ORF6	61	D61H	Gat	Cat	444	444	AY.15	0.986667
ORF6	61	D61H	Gat	Cat	154	181	B.1.1.7	0.000138
ORF6	61	D61H	Gat	Cat	112	113	AY.68	0.03066
ORF6	61	D61H	Gat	Cat	74	87	AY.4	0.000115
ORF6	61	D61H	Gat	Cat	75	75	AY.13	0.012073
ORF6	61	D61H	Gat	Cat	66	67	B.1.617.2	0.000249
ORF6	61	D61H	Gat	Cat	46	46	B.1.436	0.047325
ORF6	61	D61H	Gat	Cat	29	30	B.1.1.519	0.001152
ORF6	61	D61H	Gat	Cat	16	27	B.1	0.000147
ORF6	61	D61H	Gat	Cat	18	18	AY.26	0.00051
ORF6	61	D61H	Gat	Cat	13	17	B.1.2	0.000114
ORF6	61	D61H	Gat	Cat	13	14	AY.44	0.000079
ORF6	61	D61H	Gat	Cat	13	13	AY.105	0.00836
ORF6	61	D61H	Gat	Cat	9	12	B.1.177	0.000119
ORF6	61	D61H	Gat	Cat	12	12	D.2	0.0009
ORF6	61	D61H	Gat	Cat	10	11	AY.25	0.00006
ORF6	61	D61H	Gat	Cat	9	11	AY.3	0.00009
ORF6	61	D61H	Gat	Cat	9	11	C.37	0.001045
ORF6	61	D61H	Gat	Cat	11	11	P.1	0.000173
ORF6	61	D61H	Gat	Cat	10	10	AY.55	0.009174
ORF6	61	D61H	Gat	Cat	6	9	B.1.1	0.000109
ORF6	61	D61H	Gat	Cat	7	8	AY.61	0.000733
ORF6	61	D61H	Gat	Cat	4	8	B.1.1.279	0.004484
ORF6	61	D61H	Gat	Cat	8	8	B.1.429	0.000188
ORF6	61	D61H	Gat	Cat	7	8	B.1.526	0.000165
ORF6	61	D61H	Gat	Cat	5	7	AY.75	0.00028
ORF6	61	D61H	Gat	Cat	7	7	B.1.1.214	0.000388
ORF6	61	D61H	Gat	Cat	6	7	B.1.617.1	0.000774
ORF6	61	D61H	Gat	Cat	6	7	Q.1	0.000758
ORF6	61	D61H	Gat	Cat	6	6	AY.43	0.000027
ORF6	61	D61H	Gat	Cat	6	6	AY.9	0.000406
ORF6	61	D61H	Gat	Cat	6	6	B.1.177.86	0.001101
ORF6	61	D61H	Gat	Cat	6	6	B.1.408	0.02214
ORF6	61	D61H	Gat	Cat	5	5	B.1.177.4	0.001055
ORF6	61	D61H	Gat	Cat	5	5	B.1.351.2	0.001513
ORF6	61	D61H	Gat	Cat	2	4		0.111111
ORF6	61	D61H	Gat	Cat	4	4	AY.41	0.001176
ORF6	61	D61H	Gat	Cat	3	4	AY.54	0.000286
ORF6	61	D61H	Gat	Cat	3	4	B.1.1.306	0.001315
ORF6	61	D61H	Gat	Cat	3	4	B.1.177.21	0.000229
ORF6	61	D61H	Gat	Cat	4	4	B.1.351	0.000119
ORF6	61	D61H	Gat	Cat	3	4	B.1.369	0.000856
ORF6	61	D61H	Gat	Cat	2	3	AY.117	0.000169
ORF6	61	D61H	Gat	Cat	2	3	AY.5	0.000041
ORF6	61	D61H	Gat	Cat	3	3	AY.75.1	0.000541
ORF6	61	D61H	Gat	Cat	1	3	B.1.1.298	0.000862
ORF6	61	D61H	Gat	Cat	3	3	B.1.1.302	0.006224
ORF6	61	D61H	Gat	Cat	3	3	B.1.177.32	0.004049
ORF6	61	D61H	Gat	Cat	2	3	B.1.240	0.000431
ORF6	61	D61H	Gat	Cat	3	3	B.1.241	0.002435
ORF6	61	D61H	Gat	Cat	3	3	B.1.258	0.0002
ORF6	61	D61H	Gat	Cat	3	3	B.1.634	0.010274
ORF6	61	D61H	Gat	Cat	2	3	B.1.637	0.000146
ORF6	61	D61H	Gat	Cat	1	2	A	0.000387
ORF6	61	D61H	Gat	Cat	1	2	A.2.5.2	0.001572
ORF6	61	D61H	Gat	Cat	2	2	AY.102	0.000053
ORF6	61	D61H	Gat	Cat	1	2	AY.113	0.000142
ORF6	61	D61H	Gat	Cat	2	2	AY.120	0.000074
ORF6	61	D61H	Gat	Cat	2	2	AY.23	0.000139
ORF6	61	D61H	Gat	Cat	1	2	AY.23.1	0.000417
ORF6	61	D61H	Gat	Cat	2	2	AY.38	0.000999
ORF6	61	D61H	Gat	Cat	2	2	AY.47	0.000062
ORF6	61	D61H	Gat	Cat	2	2	AY.5.3	0.000675
ORF6	61	D61H	Gat	Cat	1	2	AY.94	0.000443
ORF6	61	D61H	Gat	Cat	1	2	AY.98.1	0.000048
ORF6	61	D61H	Gat	Cat	2	2	B.1.1.311	0.000716
ORF6	61	D61H	Gat	Cat	1	2	B.1.160.11	0.005714
ORF6	61	D61H	Gat	Cat	2	2	B.1.177.72	0.00678
ORF6	61	D61H	Gat	Cat	2	2	B.1.234	0.000264
ORF6	61	D61H	Gat	Cat	1	2	B.1.243	0.00007
ORF6	61	D61H	Gat	Cat	1	2	B.1.3	0.002618
ORF6	61	D61H	Gat	Cat	2	2	B.1.311	0.000549
ORF6	61	D61H	Gat	Cat	1	2	B.1.438.1	0.000107
ORF6	61	D61H	Gat	Cat	2	2	B.1.509	0.001732
ORF6	61	D61H	Gat	Cat	1	2	B.1.582	0.000491
ORF6	61	D61H	Gat	Cat	1	2	B.3	0.000831
ORF6	61	D61H	Gat	Cat	1	2	B.4.7	0.010101
ORF6	61	D61H	Gat	Cat	1	2	B.40	0.000364
ORF6	61	D61H	Gat	Cat	2	2	P.1.12	0.000968
ORF6	61	D61H	Gat	Cat	1	2	P.1.15	0.000232
ORF6	61	D61H	Gat	Cat	2	2	P.1.2	0.002312
ORF6	61	D61H	Gat	Cat	1	1	AY.10	0.00053
ORF6	61	D61H	Gat	Cat	1	1	AY.103	0.000006
ORF6	61	D61H	Gat	Cat	1	1	AY.109	0.00074
ORF6	61	D61H	Gat	Cat	1	1	AY.116.1	0.000311
ORF6	61	D61H	Gat	Cat	1	1	AY.118	0.000063
ORF6	61	D61H	Gat	Cat	1	1	AY.19	0.00114
ORF6	61	D61H	Gat	Cat	1	1	AY.2	0.000356
ORF6	61	D61H	Gat	Cat	1	1	AY.36	0.000148
ORF6	61	D61H	Gat	Cat	1	1	AY.4.2	0.000022
ORF6	61	D61H	Gat	Cat	1	1	AY.4.2.1	0.000149
ORF6	61	D61H	Gat	Cat	1	1	AY.46	0.000104
ORF6	61	D61H	Gat	Cat	1	1	AY.52	0.000814
ORF6	61	D61H	Gat	Cat	1	1	AY.58	0.000907
ORF6	61	D61H	Gat	Cat	1	1	AY.6	0.000041
ORF6	61	D61H	Gat	Cat	1	1	AY.60	0.000938
ORF6	61	D61H	Gat	Cat	1	1	AY.69	0.000187
ORF6	61	D61H	Gat	Cat	1	1	AY.71	0.000475
ORF6	61	D61H	Gat	Cat	1	1	AY.74	0.000116
ORF6	61	D61H	Gat	Cat	1	1	AY.77	0.001127
ORF6	61	D61H	Gat	Cat	1	1	AY.9.2	0.000037
ORF6	61	D61H	Gat	Cat	1	1	AY.98	0.000079
ORF6	61	D61H	Gat	Cat	1	1	AY.99.2	0.000092
ORF6	61	D61H	Gat	Cat	1	1	B.1.1.241	0.00207
ORF6	61	D61H	Gat	Cat	1	1	B.1.1.309	0.005848
ORF6	61	D61H	Gat	Cat	1	1	B.1.117	0.0125
ORF6	61	D61H	Gat	Cat	1	1	B.1.258.19	0.007092
ORF6	61	D61H	Gat	Cat	1	1	B.1.367	0.000792
ORF6	61	D61H	Gat	Cat	1	1	B.1.37	0.014706
ORF6	61	D61H	Gat	Cat	1	1	B.1.371	0.001122
ORF6	61	D61H	Gat	Cat	1	1	B.1.396	0.000706
ORF6	61	D61H	Gat	Cat	1	1	B.1.466.2	0.000391
ORF6	61	D61H	Gat	Cat	1	1	B.1.470	0.001404
ORF6	61	D61H	Gat	Cat	1	1	B.1.525	0.000113
ORF6	61	D61H	Gat	Cat	1	1	B.1.561	0.000397
ORF6	61	D61H	Gat	Cat	1	1	B.1.577	0.000687
ORF6	61	D61H	Gat	Cat	1	1	B.1.585	0.027778
ORF6	61	D61H	Gat	Cat	1	1	P.1.14	0.000048
ORF6	61	D61H	Gat	Cat	1	1	Q.8	0.000165
ORF6	61	D61H	Gat	Cat	1	1	R.1	0.00009

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.