CoV-GLUE Mutation

CoV-GLUE Mutation: ORF = ORF6 : CodonNum = 56 & Codon = cGa

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORF	CodonNum	Mut	ORF1abMut	MutType	RefCodon	MutCodon	AACount	CodonCount	CodonProp	Genome Position
ORF6	56	Q56R		nonsyn	cAa	cGa	2077	2075	0.999037	27367-27369

Details of the mutation no within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORF	CodonNum	Mut	RefCodon	MutCodon	CodonCount	AACount	Lineage	LineageCodonProp
ORF6	56	Q56R	cAa	cGa	2075	2077	All	0.000397
ORF6	56	Q56R	cAa	cGa	1797	1797	AY.67	0.834262
ORF6	56	Q56R	cAa	cGa	95	95	B.1.617.2	0.000358
ORF6	56	Q56R	cAa	cGa	63	63	AY.39.1	0.002496
ORF6	56	Q56R	cAa	cGa	14	14	B.1.1.7	0.000013
ORF6	56	Q56R	cAa	cGa	12	12	AY.62	0.005229
ORF6	56	Q56R	cAa	cGa	9	9	AY.103	0.000056
ORF6	56	Q56R	cAa	cGa	6	7	AY.44	0.000037
ORF6	56	Q56R	cAa	cGa	7	7	AY.69	0.001307
ORF6	56	Q56R	cAa	cGa	5	5	AY.47	0.000156
ORF6	56	Q56R	cAa	cGa	4	4	AY.4	0.000006
ORF6	56	Q56R	cAa	cGa	3	3	AY.20	0.000117
ORF6	56	Q56R	cAa	cGa	3	3	AY.25	0.000018
ORF6	56	Q56R	cAa	cGa	3	3	AY.43	0.000013
ORF6	56	Q56R	cAa	cGa	3	3	AY.75.1	0.000541
ORF6	56	Q56R	cAa	cGa	3	3	B	0.000383
ORF6	56	Q56R	cAa	cGa	3	3	B.1	0.000027
ORF6	56	Q56R	cAa	cGa	3	3	B.1.2	0.000026
ORF6	56	Q56R	cAa	cGa	2	2	AY.100	0.000092
ORF6	56	Q56R	cAa	cGa	2	2	AY.24	0.000862
ORF6	56	Q56R	cAa	cGa	2	2	AY.26	0.000057
ORF6	56	Q56R	cAa	cGa	2	2	AY.39	0.000049
ORF6	56	Q56R	cAa	cGa	2	2	AY.52	0.001629
ORF6	56	Q56R	cAa	cGa	2	2	AY.61	0.00021
ORF6	56	Q56R	cAa	cGa	2	2	AY.75	0.000112
ORF6	56	Q56R	cAa	cGa	2	2	AY.9.2	0.000073
ORF6	56	Q56R	cAa	cGa	2	2	B.1.525	0.000226
ORF6	56	Q56R	cAa	cGa	1	1	AE.8	0.000489
ORF6	56	Q56R	cAa	cGa	1	1	AY.10	0.00053
ORF6	56	Q56R	cAa	cGa	1	1	AY.102	0.000027
ORF6	56	Q56R	cAa	cGa	1	1	AY.110	0.000113
ORF6	56	Q56R	cAa	cGa	1	1	AY.117	0.000085
ORF6	56	Q56R	cAa	cGa	1	1	AY.12	0.000316
ORF6	56	Q56R	cAa	cGa	1	1	AY.16.1	0.00047
ORF6	56	Q56R	cAa	cGa	1	1	AY.23	0.00007
ORF6	56	Q56R	cAa	cGa	1	1	AY.33	0.000067
ORF6	56	Q56R	cAa	cGa	1	1	AY.40	0.000964
ORF6	56	Q56R	cAa	cGa	1	1	AY.45	0.000122
ORF6	56	Q56R	cAa	cGa	1	1	AY.5	0.000021
ORF6	56	Q56R	cAa	cGa	1	1	AY.65	0.000533
ORF6	56	Q56R	cAa	cGa	1	1	AY.70	0.000209
ORF6	56	Q56R	cAa	cGa	1	1	AY.92	0.000287
ORF6	56	Q56R	cAa	cGa	1	1	AY.93	0.000273
ORF6	56	Q56R	cAa	cGa	1	1	AY.98.1	0.000048
ORF6	56	Q56R	cAa	cGa	1	1	B.1.177.10	0.000878
ORF6	56	Q56R	cAa	cGa	1	1	B.1.351	0.00003
ORF6	56	Q56R	cAa	cGa	1	1	B.1.432	0.011236
ORF6	56	Q56R	cAa	cGa	1	1	B.1.575	0.000303
ORF6	56	Q56R	cAa	cGa	1	1	B.1.596.1	0.009346
ORF6	56	Q56R	cAa	cGa	1	1	B.1.617.1	0.000129
ORF6	56	Q56R	cAa	cGa	1	1	P.1	0.000016

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.