CoV-GLUE | Mutations | Mutation
Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):
ORF | CodonNum | Mut | ORF1abMut | MutType | RefCodon | MutCodon | AACount | CodonCount | CodonProp | Genome Position |
ORF3a | 91 | Y91Y | syn | taC | taT | 6806 | 6806 | 1 | 25663-25665 |
Details of the mutation Y91Y within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):
ORF | CodonNum | Mut | RefCodon | MutCodon | CodonCount | AACount | Lineage | LineageCodonProp |
ORF3a | 91 | Y91Y | taC | taT | 6806 | 6806 | All | 0.001302 |
ORF3a | 91 | Y91Y | taC | taT | 1620 | 1620 | AY.118 | 0.101491 |
ORF3a | 91 | Y91Y | taC | taT | 1051 | 1051 | AY.4 | 0.001636 |
ORF3a | 91 | Y91Y | taC | taT | 720 | 720 | B.1.1.7 | 0.000645 |
ORF3a | 91 | Y91Y | taC | taT | 390 | 390 | B.1.177 | 0.005135 |
ORF3a | 91 | Y91Y | taC | taT | 377 | 377 | AY.44 | 0.002295 |
ORF3a | 91 | Y91Y | taC | taT | 301 | 301 | P.6 | 0.946541 |
ORF3a | 91 | Y91Y | taC | taT | 244 | 244 | B.1 | 0.002235 |
ORF3a | 91 | Y91Y | taC | taT | 155 | 155 | AY.43 | 0.000687 |
ORF3a | 91 | Y91Y | taC | taT | 154 | 154 | AY.25 | 0.000926 |
ORF3a | 91 | Y91Y | taC | taT | 140 | 140 | B.1.617.2 | 0.000527 |
ORF3a | 91 | Y91Y | taC | taT | 129 | 129 | B.1.2 | 0.001136 |
ORF3a | 91 | Y91Y | taC | taT | 124 | 124 | B.1.369 | 0.035368 |
ORF3a | 91 | Y91Y | taC | taT | 116 | 116 | B.1.532 | 0.720497 |
ORF3a | 91 | Y91Y | taC | taT | 101 | 101 | AY.110 | 0.011382 |
ORF3a | 91 | Y91Y | taC | taT | 86 | 86 | AY.3 | 0.000855 |
ORF3a | 91 | Y91Y | taC | taT | 66 | 66 | AY.9.2 | 0.002424 |
ORF3a | 91 | Y91Y | taC | taT | 63 | 63 | AY.103 | 0.000391 |
ORF3a | 91 | Y91Y | taC | taT | 63 | 63 | B.12 | 0.403846 |
ORF3a | 91 | Y91Y | taC | taT | 47 | 47 | B.1.103 | 0.903846 |
ORF3a | 91 | Y91Y | taC | taT | 43 | 43 | P.1 | 0.000677 |
ORF3a | 91 | Y91Y | taC | taT | 40 | 40 | B.1.160 | 0.001248 |
ORF3a | 91 | Y91Y | taC | taT | 38 | 38 | P.1.15 | 0.008829 |
ORF3a | 91 | Y91Y | taC | taT | 37 | 37 | AY.98 | 0.002923 |
ORF3a | 91 | Y91Y | taC | taT | 37 | 37 | B.1.1 | 0.000671 |
ORF3a | 91 | Y91Y | taC | taT | 32 | 32 | B.1.1.214 | 0.001775 |
ORF3a | 91 | Y91Y | taC | taT | 31 | 31 | AY.46.2 | 0.019695 |
ORF3a | 91 | Y91Y | taC | taT | 28 | 28 | B.1.561 | 0.011116 |
ORF3a | 91 | Y91Y | taC | taT | 23 | 23 | B.1.526 | 0.000541 |
ORF3a | 91 | Y91Y | taC | taT | 21 | 21 | B.1.1.519 | 0.000834 |
ORF3a | 91 | Y91Y | taC | taT | 18 | 18 | B.1.596 | 0.001568 |
ORF3a | 91 | Y91Y | taC | taT | 17 | 17 | AY.120.1 | 0.005457 |
ORF3a | 91 | Y91Y | taC | taT | 17 | 17 | AY.47 | 0.000529 |
ORF3a | 91 | Y91Y | taC | taT | 16 | 16 | AY.5 | 0.00033 |
ORF3a | 91 | Y91Y | taC | taT | 16 | 16 | B.1.1.337 | 0.057554 |
ORF3a | 91 | Y91Y | taC | taT | 15 | 15 | B.1.1.41 | 0.094937 |
ORF3a | 91 | Y91Y | taC | taT | 15 | 15 | C.37 | 0.001741 |
ORF3a | 91 | Y91Y | taC | taT | 12 | 12 | B.1.351 | 0.000357 |
ORF3a | 91 | Y91Y | taC | taT | 11 | 11 | AY.102 | 0.000292 |
ORF3a | 91 | Y91Y | taC | taT | 11 | 11 | B.1.1.50 | 0.007468 |
ORF3a | 91 | Y91Y | taC | taT | 11 | 11 | D.2 | 0.000825 |
ORF3a | 91 | Y91Y | taC | taT | 10 | 10 | AY.29 | 0.000158 |
ORF3a | 91 | Y91Y | taC | taT | 9 | 9 | AY.106 | 0.003014 |
ORF3a | 91 | Y91Y | taC | taT | 9 | 9 | AY.26 | 0.000255 |
ORF3a | 91 | Y91Y | taC | taT | 9 | 9 | B.1.128 | 0.005718 |
ORF3a | 91 | Y91Y | taC | taT | 9 | 9 | B.1.427 | 0.000454 |
ORF3a | 91 | Y91Y | taC | taT | 9 | 9 | B.1.429 | 0.000212 |
ORF3a | 91 | Y91Y | taC | taT | 8 | 8 | AY.39 | 0.000198 |
ORF3a | 91 | Y91Y | taC | taT | 8 | 8 | AY.75 | 0.000448 |
ORF3a | 91 | Y91Y | taC | taT | 7 | 7 | AY.120 | 0.00026 |
ORF3a | 91 | Y91Y | taC | taT | 7 | 7 | AY.46.5 | 0.001389 |
ORF3a | 91 | Y91Y | taC | taT | 7 | 7 | B.23 | 0.020468 |
ORF3a | 91 | Y91Y | taC | taT | 7 | 7 | C.36.3 | 0.003971 |
ORF3a | 91 | Y91Y | taC | taT | 7 | 7 | R.1 | 0.00063 |
ORF3a | 91 | Y91Y | taC | taT | 6 | 6 | A.3 | 0.012579 |
ORF3a | 91 | Y91Y | taC | taT | 6 | 6 | AY.4.2 | 0.00013 |
ORF3a | 91 | Y91Y | taC | taT | 6 | 6 | B.1.36.36 | 0.003612 |
ORF3a | 91 | Y91Y | taC | taT | 5 | 5 | AY.119 | 0.000177 |
ORF3a | 91 | Y91Y | taC | taT | 5 | 5 | AY.23 | 0.000349 |
ORF3a | 91 | Y91Y | taC | taT | 5 | 5 | AY.46.6 | 0.000361 |
ORF3a | 91 | Y91Y | taC | taT | 5 | 5 | B.1.1.1 | 0.001633 |
ORF3a | 91 | Y91Y | taC | taT | 5 | 5 | B.1.221 | 0.000355 |
ORF3a | 91 | Y91Y | taC | taT | 4 | 4 | AY.109 | 0.002959 |
ORF3a | 91 | Y91Y | taC | taT | 4 | 4 | AY.46 | 0.000416 |
ORF3a | 91 | Y91Y | taC | taT | 4 | 4 | B.1.1.28 | 0.001245 |
ORF3a | 91 | Y91Y | taC | taT | 4 | 4 | B.1.1.398 | 0.012903 |
ORF3a | 91 | Y91Y | taC | taT | 4 | 4 | B.1.146 | 0.016949 |
ORF3a | 91 | Y91Y | taC | taT | 4 | 4 | B.1.258 | 0.000266 |
ORF3a | 91 | Y91Y | taC | taT | 4 | 4 | B.1.36.29 | 0.002069 |
ORF3a | 91 | Y91Y | taC | taT | 4 | 4 | Q.3 | 0.00058 |
ORF3a | 91 | Y91Y | taC | taT | 3 | 3 | AY.100 | 0.000138 |
ORF3a | 91 | Y91Y | taC | taT | 3 | 3 | AY.113 | 0.000427 |
ORF3a | 91 | Y91Y | taC | taT | 3 | 3 | AY.116 | 0.00086 |
ORF3a | 91 | Y91Y | taC | taT | 3 | 3 | AY.121 | 0.000406 |
ORF3a | 91 | Y91Y | taC | taT | 3 | 3 | AY.14 | 0.000264 |
ORF3a | 91 | Y91Y | taC | taT | 3 | 3 | AY.20 | 0.000117 |
ORF3a | 91 | Y91Y | taC | taT | 3 | 3 | AY.24 | 0.001293 |
ORF3a | 91 | Y91Y | taC | taT | 3 | 3 | AY.4.2.1 | 0.000447 |
ORF3a | 91 | Y91Y | taC | taT | 3 | 3 | AY.45 | 0.000365 |
ORF3a | 91 | Y91Y | taC | taT | 3 | 3 | AY.46.1 | 0.00308 |
ORF3a | 91 | Y91Y | taC | taT | 3 | 3 | AY.78 | 0.004622 |
ORF3a | 91 | Y91Y | taC | taT | 3 | 3 | B.1.1.216 | 0.002671 |
ORF3a | 91 | Y91Y | taC | taT | 3 | 3 | B.1.177.16 | 0.001993 |
ORF3a | 91 | Y91Y | taC | taT | 3 | 3 | B.1.177.87 | 0.002183 |
ORF3a | 91 | Y91Y | taC | taT | 3 | 3 | B.1.525 | 0.000339 |
ORF3a | 91 | Y91Y | taC | taT | 3 | 3 | B.1.621 | 0.000266 |
ORF3a | 91 | Y91Y | taC | taT | 3 | 3 | B.1.638 | 0.157895 |
ORF3a | 91 | Y91Y | taC | taT | 3 | 3 | C.35 | 0.002322 |
ORF3a | 91 | Y91Y | taC | taT | 3 | 3 | P.1.12 | 0.001452 |
ORF3a | 91 | Y91Y | taC | taT | 3 | 3 | P.1.14 | 0.000143 |
ORF3a | 91 | Y91Y | taC | taT | 3 | 3 | P.1.5 | 0.230769 |
ORF3a | 91 | Y91Y | taC | taT | 2 | 2 | AY.104 | 0.003968 |
ORF3a | 91 | Y91Y | taC | taT | 2 | 2 | AY.117 | 0.000169 |
ORF3a | 91 | Y91Y | taC | taT | 2 | 2 | AY.16.1 | 0.00094 |
ORF3a | 91 | Y91Y | taC | taT | 2 | 2 | AY.21 | 0.003795 |
ORF3a | 91 | Y91Y | taC | taT | 2 | 2 | AY.37 | 0.000632 |
ORF3a | 91 | Y91Y | taC | taT | 2 | 2 | AY.39.1 | 0.000079 |
ORF3a | 91 | Y91Y | taC | taT | 2 | 2 | AY.4.5 | 0.000215 |
ORF3a | 91 | Y91Y | taC | taT | 2 | 2 | AY.40 | 0.001929 |
ORF3a | 91 | Y91Y | taC | taT | 2 | 2 | AY.42 | 0.00008 |
ORF3a | 91 | Y91Y | taC | taT | 2 | 2 | AY.54 | 0.000191 |
ORF3a | 91 | Y91Y | taC | taT | 2 | 2 | B.1.1.115 | 0.017857 |
ORF3a | 91 | Y91Y | taC | taT | 2 | 2 | B.1.1.360 | 0.0625 |
ORF3a | 91 | Y91Y | taC | taT | 2 | 2 | B.1.1.432 | 0.002532 |
ORF3a | 91 | Y91Y | taC | taT | 2 | 2 | B.1.177.62 | 0.002384 |
ORF3a | 91 | Y91Y | taC | taT | 2 | 2 | B.1.177.7 | 0.00033 |
ORF3a | 91 | Y91Y | taC | taT | 2 | 2 | B.1.177.79 | 0.004684 |
ORF3a | 91 | Y91Y | taC | taT | 2 | 2 | B.1.239 | 0.002442 |
ORF3a | 91 | Y91Y | taC | taT | 2 | 2 | B.1.243 | 0.000139 |
ORF3a | 91 | Y91Y | taC | taT | 2 | 2 | B.1.36 | 0.000292 |
ORF3a | 91 | Y91Y | taC | taT | 2 | 2 | B.1.462 | 0.014493 |
ORF3a | 91 | Y91Y | taC | taT | 2 | 2 | B.1.575 | 0.000607 |
ORF3a | 91 | Y91Y | taC | taT | 2 | 2 | B.1.595 | 0.000522 |
ORF3a | 91 | Y91Y | taC | taT | 2 | 2 | B.1.627 | 0.00404 |
ORF3a | 91 | Y91Y | taC | taT | 2 | 2 | B.1.637 | 0.000146 |
ORF3a | 91 | Y91Y | taC | taT | 2 | 2 | B.3.1 | 0.003317 |
ORF3a | 91 | Y91Y | taC | taT | 2 | 2 | B.6 | 0.00182 |
ORF3a | 91 | Y91Y | taC | taT | 2 | 2 | C.36 | 0.001821 |
ORF3a | 91 | Y91Y | taC | taT | 2 | 2 | P.1.2 | 0.002312 |
ORF3a | 91 | Y91Y | taC | taT | 2 | 2 | P.2 | 0.000373 |
ORF3a | 91 | Y91Y | taC | taT | 1 | 1 | 0.055556 | |
ORF3a | 91 | Y91Y | taC | taT | 1 | 1 | A.2.5.2 | 0.001572 |
ORF3a | 91 | Y91Y | taC | taT | 1 | 1 | A.27 | 0.001656 |
ORF3a | 91 | Y91Y | taC | taT | 1 | 1 | AY.116.1 | 0.000311 |
ORF3a | 91 | Y91Y | taC | taT | 1 | 1 | AY.120.2 | 0.001285 |
ORF3a | 91 | Y91Y | taC | taT | 1 | 1 | AY.27 | 0.000065 |
ORF3a | 91 | Y91Y | taC | taT | 1 | 1 | AY.29.1 | 0.000221 |
ORF3a | 91 | Y91Y | taC | taT | 1 | 1 | AY.30 | 0.000396 |
ORF3a | 91 | Y91Y | taC | taT | 1 | 1 | AY.33 | 0.000067 |
ORF3a | 91 | Y91Y | taC | taT | 1 | 1 | AY.36 | 0.000148 |
ORF3a | 91 | Y91Y | taC | taT | 1 | 1 | AY.38 | 0.000499 |
ORF3a | 91 | Y91Y | taC | taT | 1 | 1 | AY.39.2 | 0.001541 |
ORF3a | 91 | Y91Y | taC | taT | 1 | 1 | AY.41 | 0.000294 |
ORF3a | 91 | Y91Y | taC | taT | 1 | 1 | AY.46.4 | 0.000165 |
ORF3a | 91 | Y91Y | taC | taT | 1 | 1 | AY.48 | 0.000465 |
ORF3a | 91 | Y91Y | taC | taT | 1 | 1 | AY.5.3 | 0.000337 |
ORF3a | 91 | Y91Y | taC | taT | 1 | 1 | AY.52 | 0.000814 |
ORF3a | 91 | Y91Y | taC | taT | 1 | 1 | AY.55 | 0.000917 |
ORF3a | 91 | Y91Y | taC | taT | 1 | 1 | AY.6 | 0.000041 |
ORF3a | 91 | Y91Y | taC | taT | 1 | 1 | AY.61 | 0.000105 |
ORF3a | 91 | Y91Y | taC | taT | 1 | 1 | AY.62 | 0.000436 |
ORF3a | 91 | Y91Y | taC | taT | 1 | 1 | AY.65 | 0.000533 |
ORF3a | 91 | Y91Y | taC | taT | 1 | 1 | AY.67 | 0.000464 |
ORF3a | 91 | Y91Y | taC | taT | 1 | 1 | AY.68 | 0.000274 |
ORF3a | 91 | Y91Y | taC | taT | 1 | 1 | AY.74 | 0.000116 |
ORF3a | 91 | Y91Y | taC | taT | 1 | 1 | AY.87 | 0.000833 |
ORF3a | 91 | Y91Y | taC | taT | 1 | 1 | AY.96 | 0.002075 |
ORF3a | 91 | Y91Y | taC | taT | 1 | 1 | AY.97 | 0.001701 |
ORF3a | 91 | Y91Y | taC | taT | 1 | 1 | AY.98.1 | 0.000048 |
ORF3a | 91 | Y91Y | taC | taT | 1 | 1 | AY.99.2 | 0.000092 |
ORF3a | 91 | Y91Y | taC | taT | 1 | 1 | B | 0.000128 |
ORF3a | 91 | Y91Y | taC | taT | 1 | 1 | B.1.1.157 | 0.000913 |
ORF3a | 91 | Y91Y | taC | taT | 1 | 1 | B.1.1.170 | 0.001247 |
ORF3a | 91 | Y91Y | taC | taT | 1 | 1 | B.1.1.174 | 0.003378 |
ORF3a | 91 | Y91Y | taC | taT | 1 | 1 | B.1.1.220 | 0.001859 |
ORF3a | 91 | Y91Y | taC | taT | 1 | 1 | B.1.1.222 | 0.000204 |
ORF3a | 91 | Y91Y | taC | taT | 1 | 1 | B.1.1.294 | 0.001266 |
ORF3a | 91 | Y91Y | taC | taT | 1 | 1 | B.1.1.33 | 0.000421 |
ORF3a | 91 | Y91Y | taC | taT | 1 | 1 | B.1.177.48 | 0.003125 |
ORF3a | 91 | Y91Y | taC | taT | 1 | 1 | B.1.177.5 | 0.001242 |
ORF3a | 91 | Y91Y | taC | taT | 1 | 1 | B.1.177.65 | 0.000665 |
ORF3a | 91 | Y91Y | taC | taT | 1 | 1 | B.1.214.2 | 0.0006 |
ORF3a | 91 | Y91Y | taC | taT | 1 | 1 | B.1.219 | 0.009434 |
ORF3a | 91 | Y91Y | taC | taT | 1 | 1 | B.1.258.17 | 0.000104 |
ORF3a | 91 | Y91Y | taC | taT | 1 | 1 | B.1.311 | 0.000275 |
ORF3a | 91 | Y91Y | taC | taT | 1 | 1 | B.1.36.18 | 0.00042 |
ORF3a | 91 | Y91Y | taC | taT | 1 | 1 | B.1.36.8 | 0.001 |
ORF3a | 91 | Y91Y | taC | taT | 1 | 1 | B.1.366 | 0.004878 |
ORF3a | 91 | Y91Y | taC | taT | 1 | 1 | B.1.389 | 0.001002 |
ORF3a | 91 | Y91Y | taC | taT | 1 | 1 | B.1.451 | 0.008197 |
ORF3a | 91 | Y91Y | taC | taT | 1 | 1 | B.1.465 | 0.003802 |
ORF3a | 91 | Y91Y | taC | taT | 1 | 1 | B.1.480 | 0.002488 |
ORF3a | 91 | Y91Y | taC | taT | 1 | 1 | B.1.499 | 0.00105 |
ORF3a | 91 | Y91Y | taC | taT | 1 | 1 | B.1.509 | 0.000866 |
ORF3a | 91 | Y91Y | taC | taT | 1 | 1 | B.1.555 | 0.022222 |
ORF3a | 91 | Y91Y | taC | taT | 1 | 1 | B.1.564 | 0.000426 |
ORF3a | 91 | Y91Y | taC | taT | 1 | 1 | B.1.580 | 0.004065 |
ORF3a | 91 | Y91Y | taC | taT | 1 | 1 | B.1.609 | 0.000479 |
ORF3a | 91 | Y91Y | taC | taT | 1 | 1 | B.1.617.1 | 0.000129 |
ORF3a | 91 | Y91Y | taC | taT | 1 | 1 | B.1.628 | 0.000352 |
ORF3a | 91 | Y91Y | taC | taT | 1 | 1 | B.1.78 | 0.008547 |
ORF3a | 91 | Y91Y | taC | taT | 1 | 1 | C.1 | 0.002392 |
ORF3a | 91 | Y91Y | taC | taT | 1 | 1 | C.16 | 0.00106 |
ORF3a | 91 | Y91Y | taC | taT | 1 | 1 | C.36.1 | 0.004149 |
ORF3a | 91 | Y91Y | taC | taT | 1 | 1 | C.37.1 | 0.002618 |
ORF3a | 91 | Y91Y | taC | taT | 1 | 1 | N.4 | 0.004255 |
ORF3a | 91 | Y91Y | taC | taT | 1 | 1 | P.1.7 | 0.000319 |
ORF3a | 91 | Y91Y | taC | taT | 1 | 1 | Q.1 | 0.000126 |
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CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk
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