CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF3a : Mut = V273L

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF3a273V273LnonsynGtgTtg226817860.78747826209-26211
ORF3a273V273LnonsynGtgCtg22684810.21208126209-26211
ORF3a273V273LnonsynGtGCtT226810.00044091726209-26211

Details of the mutation V273L within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF3a273V273LGtgTtg17862268All0.000342
ORF3a273V273LGtgCtg4812268All0.000092
ORF3a273V273LGtGCtT12268All0
ORF3a273V273LGtgTtg298495AY.40.000464
ORF3a273V273LGtgCtg197495AY.40.000307
ORF3a273V273LGtgTtg144202B.1.1.70.000129
ORF3a273V273LGtgCtg58202B.1.1.70.000052
ORF3a273V273LGtgTtg176196B.1.617.20.000663
ORF3a273V273LGtgCtg20196B.1.617.20.000075
ORF3a273V273LGtgTtg91107AY.430.000403
ORF3a273V273LGtgCtg16107AY.430.000071
ORF3a273V273LGtgTtg101103AY.340.009793
ORF3a273V273LGtgCtg2103AY.340.000194
ORF3a273V273LGtgTtg6492AY.440.00039
ORF3a273V273LGtgCtg2892AY.440.00017
ORF3a273V273LGtgTtg7979AY.50.001631
ORF3a273V273LGtgCtg3264AY.1030.000199
ORF3a273V273LGtgTtg3264AY.1030.000199
ORF3a273V273LGtgTtg4860AY.250.000289
ORF3a273V273LGtgCtg1260AY.250.000072
ORF3a273V273LGtgTtg5151AY.46.60.003683
ORF3a273V273LGtgTtg4045B.1.20.000352
ORF3a273V273LGtgCtg545B.1.20.000044
ORF3a273V273LGtgTtg4343AY.98.10.002083
ORF3a273V273LGtgTtg4141AY.770.046223
ORF3a273V273LGtgTtg2740AY.30.000269
ORF3a273V273LGtgCtg1340AY.30.000129
ORF3a273V273LGtgTtg3333AY.420.001328
ORF3a273V273LGtgTtg2727B.1.36.290.013968
ORF3a273V273LGtgTtg2326AY.4.20.000499
ORF3a273V273LGtgCtg326AY.4.20.000065
ORF3a273V273LGtgCtg1826B.1.4290.000424
ORF3a273V273LGtgTtg826B.1.4290.000188
ORF3a273V273LGtgTtg1618B.10.000147
ORF3a273V273LGtgCtg218B.10.000018
ORF3a273V273LGtgTtg1416AY.390.000346
ORF3a273V273LGtgCtg216AY.390.000049
ORF3a273V273LGtgCtg815AY.290.000126
ORF3a273V273LGtgTtg715AY.290.00011
ORF3a273V273LGtgTtg1515B.1.36.170.007411
ORF3a273V273LGtgTtg1215B.1.4270.000606
ORF3a273V273LGtgCtg315B.1.4270.000151
ORF3a273V273LGtgTtg1414AY.260.000396
ORF3a273V273LGtgTtg1314B.1.5960.001133
ORF3a273V273LGtgCtg114B.1.5960.000087
ORF3a273V273LGtgTtg1112AY.1020.000292
ORF3a273V273LGtgCtg112AY.1020.000027
ORF3a273V273LGtgTtg1112AY.330.000735
ORF3a273V273LGtgCtg112AY.330.000067
ORF3a273V273LGtgTtg1112AY.460.001145
ORF3a273V273LGtgCtg112AY.460.000104
ORF3a273V273LGtgTtg1212B.1.1.3620.067416
ORF3a273V273LGtgTtg1012B.1.3510.000297
ORF3a273V273LGtgCtg212B.1.3510.000059
ORF3a273V273LGtgTtg1111AY.1180.000689
ORF3a273V273LGtgTtg1011B.1.1770.000132
ORF3a273V273LGtgCtg111B.1.1770.000013
ORF3a273V273LGtgTtg1111B.1.5260.000259
ORF3a273V273LGtgTtg910AY.1000.000414
ORF3a273V273LGtgCtg110AY.1000.000046
ORF3a273V273LGtgTtg910AY.4.10.006637
ORF3a273V273LGtgCtg110AY.4.10.000737
ORF3a273V273LGtgTtg1010AY.5.10.037594
ORF3a273V273LGtgTtg89B.1.10.000145
ORF3a273V273LGtGCtT19B.1.10.000018
ORF3a273V273LGtgTtg68AY.9.20.00022
ORF3a273V273LGtgCtg28AY.9.20.000073
ORF3a273V273LGtgTtg77AY.1110.001282
ORF3a273V273LGtgTtg77AY.200.000272
ORF3a273V273LGtgCtg67AY.470.000187
ORF3a273V273LGtgTtg17AY.470.000031
ORF3a273V273LGtgTtg77AY.840.003062
ORF3a273V273LGtgTtg77P.10.00011
ORF3a273V273LGtgTtg56AY.230.000349
ORF3a273V273LGtgCtg16AY.230.00007
ORF3a273V273LGtgTtg66AY.4.40.002455
ORF3a273V273LGtgTtg66AY.5.40.00166
ORF3a273V273LGtgTtg66AY.90.000406
ORF3a273V273LGtgTtg66B.1.1.2140.000333
ORF3a273V273LGtgTtg66B.1.1.3180.001811
ORF3a273V273LGtgTtg56B.1.6210.000443
ORF3a273V273LGtgCtg16B.1.6210.000089
ORF3a273V273LGtgTtg66P.20.00112
ORF3a273V273LGtgTtg45AY.1190.000141
ORF3a273V273LGtgCtg15AY.1190.000035
ORF3a273V273LGtgTtg55AY.4.2.10.000745
ORF3a273V273LGtgTtg55AY.4.50.000537
ORF3a273V273LGtgCtg35AY.410.000882
ORF3a273V273LGtgTtg25AY.410.000588
ORF3a273V273LGtgTtg45AY.450.000487
ORF3a273V273LGtgCtg15AY.450.000122
ORF3a273V273LGtgTtg55AY.580.004537
ORF3a273V273LGtgTtg45AY.850.001709
ORF3a273V273LGtgCtg15AY.850.000427
ORF3a273V273LGtgTtg55AY.900.003422
ORF3a273V273LGtgCtg35AY.980.000237
ORF3a273V273LGtgTtg25AY.980.000158
ORF3a273V273LGtgTtg55B.1.4090.003906
ORF3a273V273LGtgTtg34AY.1210.000406
ORF3a273V273LGtgCtg14AY.1210.000135
ORF3a273V273LGtgTtg44AY.46.50.000794
ORF3a273V273LGtgTtg34AY.60.000123
ORF3a273V273LGtgCtg14AY.60.000041
ORF3a273V273LGtgTtg34AY.750.000168
ORF3a273V273LGtgCtg14AY.750.000056
ORF3a273V273LGtgTtg44AZ.20.003284
ORF3a273V273LGtgTtg44B.1.1.5190.000159
ORF3a273V273LGtgTtg44B.1.5950.001044
ORF3a273V273LGtgCtg44B.1.80.00789
ORF3a273V273LGtgCtg33AY.1010.001471
ORF3a273V273LGtgTtg33AY.1130.000427
ORF3a273V273LGtgCtg23AY.1200.000074
ORF3a273V273LGtgTtg13AY.1200.000037
ORF3a273V273LGtgTtg33AY.710.001425
ORF3a273V273LGtgTtg33AY.99.20.000276
ORF3a273V273LGtgTtg23B.1.2430.000139
ORF3a273V273LGtgCtg13B.1.2430.00007
ORF3a273V273LGtgTtg33B.1.3110.000824
ORF3a273V273LGtgTtg33B.1.5250.000339
ORF3a273V273LGtgTtg33C.370.000348
ORF3a273V273LGtgTtg22A0.000774
ORF3a273V273LGtgTtg22AY.160.000759
ORF3a273V273LGtgTtg22AY.3.10.000171
ORF3a273V273LGtgCtg12AY.34.10.00051
ORF3a273V273LGtgTtg12AY.34.10.00051
ORF3a273V273LGtgTtg22AY.70.000392
ORF3a273V273LGtgTtg12AY.7.10.000113
ORF3a273V273LGtgCtg12AY.7.10.000113
ORF3a273V273LGtgTtg22AY.920.000575
ORF3a273V273LGtgTtg22AY.930.000546
ORF3a273V273LGtgTtg22AY.940.000885
ORF3a273V273LGtgCtg22AZ.10.001735
ORF3a273V273LGtgTtg22B.1.1.2220.000408
ORF3a273V273LGtgCtg22B.1.1.2360.013793
ORF3a273V273LGtgTtg22B.1.1.370.000386
ORF3a273V273LGtgTtg22B.1.1.4090.005666
ORF3a273V273LGtgTtg12B.1.1.500.000679
ORF3a273V273LGtgCtg12B.1.1.500.000679
ORF3a273V273LGtgTtg22B.1.177.820.000955
ORF3a273V273LGtgTtg22B.1.177.830.002963
ORF3a273V273LGtgTtg22B.1.360.000292
ORF3a273V273LGtgTtg22B.1.5820.000981
ORF3a273V273LGtgTtg22B.1.6370.000146
ORF3a273V273LGtgTtg22Q.10.000253
ORF3a273V273LGtgCtg22Q.30.00029
ORF3a273V273LGtgTtg11AY.100.00053
ORF3a273V273LGtgTtg11AY.1050.000643
ORF3a273V273LGtgTtg11AY.1060.000335
ORF3a273V273LGtgTtg11AY.1160.000287
ORF3a273V273LGtgTtg11AY.1170.000085
ORF3a273V273LGtgTtg11AY.120.000316
ORF3a273V273LGtgCtg11AY.300.000396
ORF3a273V273LGtgTtg11AY.360.000148
ORF3a273V273LGtgTtg11AY.39.10.00004
ORF3a273V273LGtgCtg11AY.400.000964
ORF3a273V273LGtgTtg11AY.46.40.000165
ORF3a273V273LGtgTtg11AY.480.000465
ORF3a273V273LGtgTtg11AY.550.000917
ORF3a273V273LGtgTtg11AY.590.00053
ORF3a273V273LGtgCtg11AY.610.000105
ORF3a273V273LGtgTtg11AY.680.000274
ORF3a273V273LGtgCtg11AY.690.000187
ORF3a273V273LGtgTtg11AY.7.20.000559
ORF3a273V273LGtgCtg11AY.730.000665
ORF3a273V273LGtgTtg11AY.740.000116
ORF3a273V273LGtgTtg11AY.870.000833
ORF3a273V273LGtgTtg11AY.960.002075
ORF3a273V273LGtgCtg11B.1.1.10.000327
ORF3a273V273LGtgTtg11B.1.1.2390.032258
ORF3a273V273LGtgTtg11B.1.1.3060.000438
ORF3a273V273LGtgTtg11B.1.1.4520.111111
ORF3a273V273LGtgTtg11B.1.1.5280.004808
ORF3a273V273LGtgTtg11B.1.1.630.000386
ORF3a273V273LGtgTtg11B.1.1120.005181
ORF3a273V273LGtgTtg11B.1.177.350.000691
ORF3a273V273LGtgTtg11B.1.177.750.001041
ORF3a273V273LGtgTtg11B.1.1990.004132
ORF3a273V273LGtgTtg11B.1.214.20.0006
ORF3a273V273LGtgTtg11B.1.2340.000132
ORF3a273V273LGtgTtg11B.1.2400.000216
ORF3a273V273LGtgTtg11B.1.258.110.000396
ORF3a273V273LGtgTtg11B.1.3690.000285
ORF3a273V273LGtgCtg11B.1.3850.010638
ORF3a273V273LGtgTtg11B.1.4260.001009
ORF3a273V273LGtgTtg11B.1.4560.003268
ORF3a273V273LGtgTtg11B.1.4680.005714
ORF3a273V273LGtgTtg11B.1.5610.000397
ORF3a273V273LGtgTtg11B.1.595.40.007299
ORF3a273V273LGtgTtg11B.1.6090.000479
ORF3a273V273LGtgCtg11B.1.6250.002353
ORF3a273V273LGtgTtg11B.1.6280.000352
ORF3a273V273LGtgCtg11C.360.000911
ORF3a273V273LGtgTtg11D.20.000075
ORF3a273V273LGtgCtg11N.50.001767
ORF3a273V273LGtgTtg11P.1.150.000232
ORF3a273V273LGtgCtg11P.1.170.000162
ORF3a273V273LGtgTtg11P.1.17.10.000875
ORF3a273V273LGtgTtg11P.1.70.000319
ORF3a273V273LGtgCtg11P.30.001595
ORF3a273V273LGtgTtg11R.10.00009

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.