CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF3a : Mut = T223A

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF3a223T223AnonsynActGct5025010.99800826059-26061
ORF3a223T223AnonsynAcTGcA50210.0019920326059-26061

Details of the mutation T223A within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF3a223T223AActGct501502All0.000096
ORF3a223T223AAcTGcA1502All0
ORF3a223T223AActGct216216B.1.2790.11094
ORF3a223T223AActGct7878B.1.177.720.264407
ORF3a223T223AActGct6161B.1.258.240.655914
ORF3a223T223AActGct3030B.1.1.70.000027
ORF3a223T223AActGct1717B.1.1770.000224
ORF3a223T223AActGct1414B.4.81
ORF3a223T223AActGct88B.1.1.10.002614
ORF3a223T223AActGct88B.1.1.330.003367
ORF3a223T223AActGct88B.1.3510.000238
ORF3a223T223AActGct77AY.40.000011
ORF3a223T223AActGct44B.10.000037
ORF3a223T223AActGct44B.1.617.20.000015
ORF3a223T223AActGct33AY.290.000047
ORF3a223T223AActGct33AY.440.000018
ORF3a223T223AActGct33B.1.36.80.003
ORF3a223T223AActGct33C.130.076923
ORF3a223T223AActGct33C.60.111111
ORF3a223T223AActGct22B0.000256
ORF3a223T223AActGct22B.1.1.280.000622
ORF3a223T223AActGct22B.1.20.000018
ORF3a223T223AActGct22B.1.2580.000133
ORF3a223T223AActGct22B.1.360.000292
ORF3a223T223AActGct22B.1.5260.000047
ORF3a223T223AActGct22P.10.000032
ORF3a223T223AAcTGcA12Q.10.000126
ORF3a223T223AActGct12Q.10.000126
ORF3a223T223AActGct11AY.200.000039
ORF3a223T223AActGct11AY.250.000006
ORF3a223T223AActGct11AY.390.000025
ORF3a223T223AActGct11AY.450.000122
ORF3a223T223AActGct11AY.460.000104
ORF3a223T223AActGct11B.1.10.000018
ORF3a223T223AActGct11B.1.1.3720.000689
ORF3a223T223AActGct11B.1.1570.002985
ORF3a223T223AActGct11B.1.160.290.004219
ORF3a223T223AActGct11B.1.36.10.00114
ORF3a223T223AActGct11B.1.36.100.004785
ORF3a223T223AActGct11B.1.4220.000812
ORF3a223T223AActGct11B.1.4680.005714
ORF3a223T223AActGct11B.40.002208
ORF3a223T223AActGct11B.4.10.018868
ORF3a223T223AActGct11Q.80.000165

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

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