CoV-GLUE | Mutations | Mutation
Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):
ORF | CodonNum | Mut | ORF1abMut | MutType | RefCodon | MutCodon | AACount | CodonCount | CodonProp | Genome Position |
ORF3a | 12 | T12I | nonsyn | aCt | aTt | 5302 | 5300 | 0.999623 | 25426-25428 | |
ORF3a | 12 | T12I | nonsyn | aCT | aTC | 5302 | 2 | 0.000377216 | 25426-25428 |
Details of the mutation T12I within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):
ORF | CodonNum | Mut | RefCodon | MutCodon | CodonCount | AACount | Lineage | LineageCodonProp |
ORF3a | 12 | T12I | aCt | aTt | 5300 | 5302 | All | 0.001014 |
ORF3a | 12 | T12I | aCT | aTC | 2 | 5302 | All | 0 |
ORF3a | 12 | T12I | aCt | aTt | 3212 | 3214 | B.1.1.7 | 0.002875 |
ORF3a | 12 | T12I | aCT | aTC | 2 | 3214 | B.1.1.7 | 0.000002 |
ORF3a | 12 | T12I | aCt | aTt | 346 | 346 | P.1 | 0.005451 |
ORF3a | 12 | T12I | aCt | aTt | 316 | 316 | AY.4 | 0.000492 |
ORF3a | 12 | T12I | aCt | aTt | 241 | 241 | B.1.160 | 0.007516 |
ORF3a | 12 | T12I | aCt | aTt | 97 | 97 | AY.25 | 0.000583 |
ORF3a | 12 | T12I | aCt | aTt | 64 | 64 | B.1.2 | 0.000564 |
ORF3a | 12 | T12I | aCt | aTt | 59 | 59 | B.1.177 | 0.000777 |
ORF3a | 12 | T12I | aCt | aTt | 56 | 56 | B.1.617.2 | 0.000211 |
ORF3a | 12 | T12I | aCt | aTt | 39 | 39 | AY.44 | 0.000237 |
ORF3a | 12 | T12I | aCt | aTt | 39 | 39 | B.1.621 | 0.003452 |
ORF3a | 12 | T12I | aCt | aTt | 38 | 38 | AY.4.2 | 0.000824 |
ORF3a | 12 | T12I | aCt | aTt | 38 | 38 | AY.43 | 0.000168 |
ORF3a | 12 | T12I | aCt | aTt | 38 | 38 | Q.1 | 0.0048 |
ORF3a | 12 | T12I | aCt | aTt | 37 | 37 | AY.113 | 0.005268 |
ORF3a | 12 | T12I | aCt | aTt | 37 | 37 | B.1.1 | 0.000671 |
ORF3a | 12 | T12I | aCt | aTt | 34 | 34 | B.1.526 | 0.000799 |
ORF3a | 12 | T12I | aCt | aTt | 27 | 27 | B.1 | 0.000247 |
ORF3a | 12 | T12I | aCt | aTt | 26 | 26 | AY.103 | 0.000161 |
ORF3a | 12 | T12I | aCt | aTt | 22 | 22 | AY.39 | 0.000544 |
ORF3a | 12 | T12I | aCt | aTt | 22 | 22 | B.1.351 | 0.000654 |
ORF3a | 12 | T12I | aCt | aTt | 19 | 19 | AY.3 | 0.000189 |
ORF3a | 12 | T12I | aCt | aTt | 17 | 17 | AY.14 | 0.001496 |
ORF3a | 12 | T12I | aCt | aTt | 17 | 17 | P.1.14 | 0.000813 |
ORF3a | 12 | T12I | aCt | aTt | 15 | 15 | B.1.637 | 0.001096 |
ORF3a | 12 | T12I | aCt | aTt | 14 | 14 | B.1.243 | 0.000974 |
ORF3a | 12 | T12I | aCt | aTt | 12 | 12 | AE.7 | 1 |
ORF3a | 12 | T12I | aCt | aTt | 12 | 12 | AY.102 | 0.000318 |
ORF3a | 12 | T12I | aCt | aTt | 12 | 12 | AY.118 | 0.000752 |
ORF3a | 12 | T12I | aCt | aTt | 12 | 12 | B.1.1.519 | 0.000477 |
ORF3a | 12 | T12I | aCt | aTt | 11 | 11 | AY.117 | 0.00093 |
ORF3a | 12 | T12I | aCt | aTt | 11 | 11 | AY.119 | 0.000388 |
ORF3a | 12 | T12I | aCt | aTt | 11 | 11 | AY.62 | 0.004793 |
ORF3a | 12 | T12I | aCt | aTt | 10 | 10 | AY.42 | 0.000402 |
ORF3a | 12 | T12I | aCt | aTt | 10 | 10 | AY.5 | 0.000206 |
ORF3a | 12 | T12I | aCt | aTt | 9 | 9 | AY.120 | 0.000335 |
ORF3a | 12 | T12I | aCt | aTt | 9 | 9 | B.1.1.316 | 0.008326 |
ORF3a | 12 | T12I | aCt | aTt | 9 | 9 | B.1.429 | 0.000212 |
ORF3a | 12 | T12I | aCt | aTt | 8 | 8 | AY.75 | 0.000448 |
ORF3a | 12 | T12I | aCt | aTt | 8 | 8 | B.1.177.33 | 0.013158 |
ORF3a | 12 | T12I | aCt | aTt | 7 | 7 | AY.100 | 0.000322 |
ORF3a | 12 | T12I | aCt | aTt | 7 | 7 | B.1.427 | 0.000353 |
ORF3a | 12 | T12I | aCt | aTt | 6 | 6 | AY.29 | 0.000095 |
ORF3a | 12 | T12I | aCt | aTt | 6 | 6 | B.1.1.1 | 0.00196 |
ORF3a | 12 | T12I | aCt | aTt | 6 | 6 | P.2 | 0.00112 |
ORF3a | 12 | T12I | aCt | aTt | 5 | 5 | AY.20 | 0.000194 |
ORF3a | 12 | T12I | aCt | aTt | 5 | 5 | AY.5.3 | 0.001687 |
ORF3a | 12 | T12I | aCt | aTt | 5 | 5 | B.1.234 | 0.00066 |
ORF3a | 12 | T12I | aCt | aTt | 5 | 5 | B.1.258.4 | 0.017241 |
ORF3a | 12 | T12I | aCt | aTt | 5 | 5 | B.1.36.36 | 0.00301 |
ORF3a | 12 | T12I | aCt | aTt | 5 | 5 | B.1.525 | 0.000566 |
ORF3a | 12 | T12I | aCt | aTt | 5 | 5 | B.1.596 | 0.000436 |
ORF3a | 12 | T12I | aCt | aTt | 5 | 5 | B.1.617.1 | 0.000645 |
ORF3a | 12 | T12I | aCt | aTt | 4 | 4 | AY.26 | 0.000113 |
ORF3a | 12 | T12I | aCt | aTt | 4 | 4 | AY.87 | 0.003331 |
ORF3a | 12 | T12I | aCt | aTt | 4 | 4 | AY.99.2 | 0.000369 |
ORF3a | 12 | T12I | aCt | aTt | 4 | 4 | B.1.221 | 0.000284 |
ORF3a | 12 | T12I | aCt | aTt | 4 | 4 | B.1.258 | 0.000266 |
ORF3a | 12 | T12I | aCt | aTt | 4 | 4 | B.1.619.1 | 0.002566 |
ORF3a | 12 | T12I | aCt | aTt | 4 | 4 | P.1.12 | 0.001936 |
ORF3a | 12 | T12I | aCt | aTt | 3 | 3 | AY.3.1 | 0.000256 |
ORF3a | 12 | T12I | aCt | aTt | 3 | 3 | AY.33 | 0.0002 |
ORF3a | 12 | T12I | aCt | aTt | 3 | 3 | AY.34 | 0.000291 |
ORF3a | 12 | T12I | aCt | aTt | 3 | 3 | AY.5.4 | 0.00083 |
ORF3a | 12 | T12I | aCt | aTt | 3 | 3 | AY.75.1 | 0.000541 |
ORF3a | 12 | T12I | aCt | aTt | 3 | 3 | B.1.1.214 | 0.000166 |
ORF3a | 12 | T12I | aCt | aTt | 3 | 3 | B.1.177.21 | 0.000229 |
ORF3a | 12 | T12I | aCt | aTt | 3 | 3 | B.1.177.77 | 0.002179 |
ORF3a | 12 | T12I | aCt | aTt | 3 | 3 | B.1.240 | 0.000647 |
ORF3a | 12 | T12I | aCt | aTt | 3 | 3 | B.1.375 | 0.002459 |
ORF3a | 12 | T12I | aCt | aTt | 3 | 3 | B.1.453 | 0.009709 |
ORF3a | 12 | T12I | aCt | aTt | 3 | 3 | B.1.469 | 0.01083 |
ORF3a | 12 | T12I | aCt | aTt | 3 | 3 | B.1.577 | 0.002062 |
ORF3a | 12 | T12I | aCt | aTt | 3 | 3 | Q.8 | 0.000495 |
ORF3a | 12 | T12I | aCt | aTt | 2 | 2 | AD.2 | 0.000438 |
ORF3a | 12 | T12I | aCt | aTt | 2 | 2 | AY.116.1 | 0.000623 |
ORF3a | 12 | T12I | aCt | aTt | 2 | 2 | AY.16 | 0.000759 |
ORF3a | 12 | T12I | aCt | aTt | 2 | 2 | AY.23 | 0.000139 |
ORF3a | 12 | T12I | aCt | aTt | 2 | 2 | AY.36 | 0.000296 |
ORF3a | 12 | T12I | aCt | aTt | 2 | 2 | AY.45 | 0.000243 |
ORF3a | 12 | T12I | aCt | aTt | 2 | 2 | AY.46 | 0.000208 |
ORF3a | 12 | T12I | aCt | aTt | 2 | 2 | AY.46.6 | 0.000144 |
ORF3a | 12 | T12I | aCt | aTt | 2 | 2 | AY.47 | 0.000062 |
ORF3a | 12 | T12I | aCt | aTt | 2 | 2 | AY.6 | 0.000082 |
ORF3a | 12 | T12I | aCt | aTt | 2 | 2 | AY.9 | 0.000135 |
ORF3a | 12 | T12I | aCt | aTt | 2 | 2 | AY.98.1 | 0.000097 |
ORF3a | 12 | T12I | aCt | aTt | 2 | 2 | B.1.1.153 | 0.002191 |
ORF3a | 12 | T12I | aCt | aTt | 2 | 2 | B.1.1.170 | 0.002494 |
ORF3a | 12 | T12I | aCt | aTt | 2 | 2 | B.1.1.210 | 0.011429 |
ORF3a | 12 | T12I | aCt | aTt | 2 | 2 | B.1.1.28 | 0.000622 |
ORF3a | 12 | T12I | aCt | aTt | 2 | 2 | B.1.1.302 | 0.004149 |
ORF3a | 12 | T12I | aCt | aTt | 2 | 2 | B.1.1.370 | 0.025316 |
ORF3a | 12 | T12I | aCt | aTt | 2 | 2 | B.1.1.521 | 0.010695 |
ORF3a | 12 | T12I | aCt | aTt | 2 | 2 | B.1.1.70 | 0.000682 |
ORF3a | 12 | T12I | aCt | aTt | 2 | 2 | B.1.177.7 | 0.00033 |
ORF3a | 12 | T12I | aCt | aTt | 2 | 2 | B.1.177.73 | 0.001133 |
ORF3a | 12 | T12I | aCt | aTt | 2 | 2 | B.1.189 | 0.008584 |
ORF3a | 12 | T12I | aCt | aTt | 2 | 2 | B.1.258.17 | 0.000208 |
ORF3a | 12 | T12I | aCt | aTt | 2 | 2 | B.1.351.3 | 0.001753 |
ORF3a | 12 | T12I | aCt | aTt | 2 | 2 | B.1.36 | 0.000292 |
ORF3a | 12 | T12I | aCt | aTt | 2 | 2 | B.1.575 | 0.000607 |
ORF3a | 12 | T12I | aCt | aTt | 2 | 2 | B.1.620 | 0.001892 |
ORF3a | 12 | T12I | aCt | aTt | 2 | 2 | B.23 | 0.005848 |
ORF3a | 12 | T12I | aCt | aTt | 2 | 2 | C.36 | 0.001821 |
ORF3a | 12 | T12I | aCt | aTt | 2 | 2 | C.37 | 0.000232 |
ORF3a | 12 | T12I | aCt | aTt | 2 | 2 | D.2 | 0.00015 |
ORF3a | 12 | T12I | aCt | aTt | 2 | 2 | P.1.10.1 | 0.01626 |
ORF3a | 12 | T12I | aCt | aTt | 2 | 2 | Q.7 | 0.002222 |
ORF3a | 12 | T12I | aCt | aTt | 1 | 1 | A.27 | 0.001656 |
ORF3a | 12 | T12I | aCt | aTt | 1 | 1 | AL.1 | 0.012987 |
ORF3a | 12 | T12I | aCt | aTt | 1 | 1 | AY.1 | 0.000396 |
ORF3a | 12 | T12I | aCt | aTt | 1 | 1 | AY.101 | 0.00049 |
ORF3a | 12 | T12I | aCt | aTt | 1 | 1 | AY.110 | 0.000113 |
ORF3a | 12 | T12I | aCt | aTt | 1 | 1 | AY.114 | 0.000231 |
ORF3a | 12 | T12I | aCt | aTt | 1 | 1 | AY.2 | 0.000356 |
ORF3a | 12 | T12I | aCt | aTt | 1 | 1 | AY.38 | 0.000499 |
ORF3a | 12 | T12I | aCt | aTt | 1 | 1 | AY.4.3 | 0.000842 |
ORF3a | 12 | T12I | aCt | aTt | 1 | 1 | AY.4.5 | 0.000107 |
ORF3a | 12 | T12I | aCt | aTt | 1 | 1 | AY.46.2 | 0.000635 |
ORF3a | 12 | T12I | aCt | aTt | 1 | 1 | AY.51 | 0.000909 |
ORF3a | 12 | T12I | aCt | aTt | 1 | 1 | AY.55 | 0.000917 |
ORF3a | 12 | T12I | aCt | aTt | 1 | 1 | AY.61 | 0.000105 |
ORF3a | 12 | T12I | aCt | aTt | 1 | 1 | AY.63 | 0.000387 |
ORF3a | 12 | T12I | aCt | aTt | 1 | 1 | AY.64 | 0.000595 |
ORF3a | 12 | T12I | aCt | aTt | 1 | 1 | AY.86 | 0.00083 |
ORF3a | 12 | T12I | aCt | aTt | 1 | 1 | AY.9.1 | 0.000084 |
ORF3a | 12 | T12I | aCt | aTt | 1 | 1 | AY.9.2 | 0.000037 |
ORF3a | 12 | T12I | aCt | aTt | 1 | 1 | AY.92 | 0.000287 |
ORF3a | 12 | T12I | aCt | aTt | 1 | 1 | AY.95 | 0.000761 |
ORF3a | 12 | T12I | aCt | aTt | 1 | 1 | AY.99 | 0.001049 |
ORF3a | 12 | T12I | aCt | aTt | 1 | 1 | AZ.1 | 0.000867 |
ORF3a | 12 | T12I | aCt | aTt | 1 | 1 | B | 0.000128 |
ORF3a | 12 | T12I | aCt | aTt | 1 | 1 | B.1.1.158 | 0.012195 |
ORF3a | 12 | T12I | aCt | aTt | 1 | 1 | B.1.1.207 | 0.001182 |
ORF3a | 12 | T12I | aCt | aTt | 1 | 1 | B.1.1.216 | 0.00089 |
ORF3a | 12 | T12I | aCt | aTt | 1 | 1 | B.1.1.229 | 0.005747 |
ORF3a | 12 | T12I | aCt | aTt | 1 | 1 | B.1.1.25 | 0.000569 |
ORF3a | 12 | T12I | aCt | aTt | 1 | 1 | B.1.1.269 | 0.001353 |
ORF3a | 12 | T12I | aCt | aTt | 1 | 1 | B.1.1.301 | 0.001179 |
ORF3a | 12 | T12I | aCt | aTt | 1 | 1 | B.1.1.306 | 0.000438 |
ORF3a | 12 | T12I | aCt | aTt | 1 | 1 | B.1.1.33 | 0.000421 |
ORF3a | 12 | T12I | aCt | aTt | 1 | 1 | B.1.1.337 | 0.003597 |
ORF3a | 12 | T12I | aCt | aTt | 1 | 1 | B.1.1.37 | 0.000193 |
ORF3a | 12 | T12I | aCt | aTt | 1 | 1 | B.1.1.400 | 0.05 |
ORF3a | 12 | T12I | aCt | aTt | 1 | 1 | B.1.1.523 | 0.001563 |
ORF3a | 12 | T12I | aCt | aTt | 1 | 1 | B.1.1.57 | 0.011494 |
ORF3a | 12 | T12I | aCt | aTt | 1 | 1 | B.1.1.89 | 0.006061 |
ORF3a | 12 | T12I | aCt | aTt | 1 | 1 | B.1.170 | 0.00431 |
ORF3a | 12 | T12I | aCt | aTt | 1 | 1 | B.1.177.16 | 0.000664 |
ORF3a | 12 | T12I | aCt | aTt | 1 | 1 | B.1.177.35 | 0.000691 |
ORF3a | 12 | T12I | aCt | aTt | 1 | 1 | B.1.177.54 | 0.000606 |
ORF3a | 12 | T12I | aCt | aTt | 1 | 1 | B.1.177.56 | 0.000668 |
ORF3a | 12 | T12I | aCt | aTt | 1 | 1 | B.1.177.60 | 0.000218 |
ORF3a | 12 | T12I | aCt | aTt | 1 | 1 | B.1.177.81 | 0.000189 |
ORF3a | 12 | T12I | aCt | aTt | 1 | 1 | B.1.177.86 | 0.000183 |
ORF3a | 12 | T12I | aCt | aTt | 1 | 1 | B.1.221.3 | 0.000833 |
ORF3a | 12 | T12I | aCt | aTt | 1 | 1 | B.1.232 | 0.000537 |
ORF3a | 12 | T12I | aCt | aTt | 1 | 1 | B.1.241 | 0.000812 |
ORF3a | 12 | T12I | aCt | aTt | 1 | 1 | B.1.265 | 0.001271 |
ORF3a | 12 | T12I | aCt | aTt | 1 | 1 | B.1.36.22 | 0.001208 |
ORF3a | 12 | T12I | aCt | aTt | 1 | 1 | B.1.36.7 | 0.004 |
ORF3a | 12 | T12I | aCt | aTt | 1 | 1 | B.1.36.9 | 0.003215 |
ORF3a | 12 | T12I | aCt | aTt | 1 | 1 | B.1.362 | 0.001541 |
ORF3a | 12 | T12I | aCt | aTt | 1 | 1 | B.1.369 | 0.000285 |
ORF3a | 12 | T12I | aCt | aTt | 1 | 1 | B.1.425 | 0.002994 |
ORF3a | 12 | T12I | aCt | aTt | 1 | 1 | B.1.466.2 | 0.000391 |
ORF3a | 12 | T12I | aCt | aTt | 1 | 1 | B.1.509 | 0.000866 |
ORF3a | 12 | T12I | aCt | aTt | 1 | 1 | B.1.588 | 0.00091 |
ORF3a | 12 | T12I | aCt | aTt | 1 | 1 | B.1.590 | 0.004545 |
ORF3a | 12 | T12I | aCt | aTt | 1 | 1 | B.1.595 | 0.000261 |
ORF3a | 12 | T12I | aCt | aTt | 1 | 1 | B.1.609 | 0.000479 |
ORF3a | 12 | T12I | aCt | aTt | 1 | 1 | B.1.623 | 0.000536 |
ORF3a | 12 | T12I | aCt | aTt | 1 | 1 | B.1.8 | 0.001972 |
ORF3a | 12 | T12I | aCt | aTt | 1 | 1 | B.1.9.5 | 0.005682 |
ORF3a | 12 | T12I | aCt | aTt | 1 | 1 | B.1.93 | 0.000934 |
ORF3a | 12 | T12I | aCt | aTt | 1 | 1 | B.58 | 0.010204 |
ORF3a | 12 | T12I | aCt | aTt | 1 | 1 | C.35 | 0.000774 |
ORF3a | 12 | T12I | aCt | aTt | 1 | 1 | K.1 | 0.02381 |
ORF3a | 12 | T12I | aCt | aTt | 1 | 1 | P.1.1 | 0.000318 |
ORF3a | 12 | T12I | aCt | aTt | 1 | 1 | P.1.10 | 0.000269 |
ORF3a | 12 | T12I | aCt | aTt | 1 | 1 | P.1.13 | 0.000898 |
ORF3a | 12 | T12I | aCt | aTt | 1 | 1 | P.1.15 | 0.000232 |
ORF3a | 12 | T12I | aCt | aTt | 1 | 1 | P.1.7 | 0.000319 |
ORF3a | 12 | T12I | aCt | aTt | 1 | 1 | Q.4 | 0.000455 |
![]() |
![]() |
CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk
|