CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF3a : Mut = S166L

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF3a166S166LnonsyntCatTa13491134900.99992625888-25890
ORF3a166S166LnonsynTCaCTa1349110.000074123525888-25890

Details of the mutation S166L within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF3a166S166LtCatTa1349013491All0.00258
ORF3a166S166LTCaCTa113491All0
ORF3a166S166LtCatTa52605260B.1.177.810.995835
ORF3a166S166LtCatTa24962496B.1.1.70.002234
ORF3a166S166LtCatTa772772B.1.1.4340.269083
ORF3a166S166LtCatTa433434AY.40.000674
ORF3a166S166LTCaCTa1434AY.40.000002
ORF3a166S166LtCatTa366366AY.430.001622
ORF3a166S166LtCatTa340340Z.10.982659
ORF3a166S166LtCatTa320320B.1.6210.028326
ORF3a166S166LtCatTa270270B.1.1.2530.676692
ORF3a166S166LtCatTa257257AY.460.026749
ORF3a166S166LtCatTa253253B.1.1770.003331
ORF3a166S166LtCatTa191191B.10.001749
ORF3a166S166LtCatTa176176P.10.002773
ORF3a166S166LtCatTa148148AY.440.000901
ORF3a166S166LtCatTa148148B.1.617.20.000557
ORF3a166S166LtCatTa104104AY.250.000626
ORF3a166S166LtCatTa9999AA.70.908257
ORF3a166S166LtCatTa9090B.1.10.001633
ORF3a166S166LtCatTa8585B.1.20.000748
ORF3a166S166LtCatTa8282AY.1030.000509
ORF3a166S166LtCatTa8181B.1.1600.002526
ORF3a166S166LtCatTa6363AY.30.000627
ORF3a166S166LtCatTa5454AY.140.004753
ORF3a166S166LtCatTa5050AY.1000.0023
ORF3a166S166LtCatTa5050B.1.1.700.017053
ORF3a166S166LtCatTa4747AY.390.001161
ORF3a166S166LtCatTa4040B.1.1.2140.002218
ORF3a166S166LtCatTa4040B.1.2430.002783
ORF3a166S166LtCatTa3838AY.50.000785
ORF3a166S166LtCatTa3737AY.290.000584
ORF3a166S166LtCatTa3737D.20.002777
ORF3a166S166LtCatTa3636B.1.4290.000847
ORF3a166S166LtCatTa3535B.1.5250.003961
ORF3a166S166LtCatTa3232B.1.617.10.004127
ORF3a166S166LtCatTa3131B.1.177.70.00511
ORF3a166S166LtCatTa2929AY.310.537037
ORF3a166S166LtCatTa2828P.20.005226
ORF3a166S166LtCatTa2626AY.330.001736
ORF3a166S166LtCatTa2626B.1.3510.000773
ORF3a166S166LtCatTa2525P.1.70.007982
ORF3a166S166LtCatTa2121AY.540.002002
ORF3a166S166LtCatTa2020AY.9.10.001674
ORF3a166S166LtCatTa2020B.1.177.620.023838
ORF3a166S166LtCatTa1919P.1.140.000908
ORF3a166S166LtCatTa1818AY.1060.006028
ORF3a166S166LtCatTa1717B.1.2580.001131
ORF3a166S166LtCatTa1616AY.1020.000424
ORF3a166S166LtCatTa1515AY.98.10.000726
ORF3a166S166LtCatTa1515B.1.1.2840.001611
ORF3a166S166LtCatTa1515B.1.177.500.070423
ORF3a166S166LtCatTa1515Q.80.002474
ORF3a166S166LtCatTa1414AY.160.005315
ORF3a166S166LtCatTa1414B.1.1990.057851
ORF3a166S166LtCatTa1313B.1.1.280.004046
ORF3a166S166LtCatTa1313B.1.360.001897
ORF3a166S166LtCatTa1313B.1.4090.010156
ORF3a166S166LtCatTa1212AY.200.000466
ORF3a166S166LtCatTa1212AY.3.10.001023
ORF3a166S166LtCatTa1212AY.4.20.00026
ORF3a166S166LtCatTa1212B.1.1.2220.002448
ORF3a166S166LtCatTa1212B.1.1.5190.000477
ORF3a166S166LtCatTa1111AY.300.004353
ORF3a166S166LtCatTa1111AY.610.001153
ORF3a166S166LtCatTa1111B.1.1.630.004244
ORF3a166S166LtCatTa1111B.1.2400.002371
ORF3a166S166LtCatTa1010B.1.1.3170.004117
ORF3a166S166LtCatTa1010B.1.3610.012887
ORF3a166S166LtCatTa99AY.450.001095
ORF3a166S166LtCatTa99AY.550.008257
ORF3a166S166LtCatTa99B.1.4990.009454
ORF3a166S166LtCatTa88AY.260.000226
ORF3a166S166LtCatTa88AY.270.000518
ORF3a166S166LtCatTa88B.1.5960.000697
ORF3a166S166LtCatTa88P.1.120.003872
ORF3a166S166LtCatTa77AY.470.000218
ORF3a166S166LtCatTa66AY.46.60.000433
ORF3a166S166LtCatTa66AY.60.000247
ORF3a166S166LtCatTa66AY.9.20.00022
ORF3a166S166LtCatTa66B.1.177.650.003992
ORF3a166S166LtCatTa66B.1.4280.006122
ORF3a166S166LtCatTa55AY.1170.000423
ORF3a166S166LtCatTa55AY.230.000349
ORF3a166S166LtCatTa55AY.39.10.000198
ORF3a166S166LtCatTa55AY.530.001438
ORF3a166S166LtCatTa55AY.590.002648
ORF3a166S166LtCatTa55B.1.1.3540.02193
ORF3a166S166LtCatTa55B.1.1.390.002548
ORF3a166S166LtCatTa55B.1.36.290.002587
ORF3a166S166LtCatTa55B.1.4200.052083
ORF3a166S166LtCatTa55B.1.4270.000252
ORF3a166S166LtCatTa44AD.20.000876
ORF3a166S166LtCatTa44AY.1180.000251
ORF3a166S166LtCatTa44AY.980.000316
ORF3a166S166LtCatTa44B.1.1.3180.001207
ORF3a166S166LtCatTa44B.1.1.370.000771
ORF3a166S166LtCatTa44B.1.1.5180.025316
ORF3a166S166LtCatTa44B.1.177.860.000734
ORF3a166S166LtCatTa44B.1.2360.008214
ORF3a166S166LtCatTa44B.1.36.80.004
ORF3a166S166LtCatTa44B.1.4700.005618
ORF3a166S166LtCatTa44B.1.5260.000094
ORF3a166S166LtCatTa33AY.1200.000112
ORF3a166S166LtCatTa33AY.1210.000406
ORF3a166S166LtCatTa33AY.4.50.000322
ORF3a166S166LtCatTa33AY.420.000121
ORF3a166S166LtCatTa33AY.46.40.000494
ORF3a166S166LtCatTa33AY.70.000588
ORF3a166S166LtCatTa33AY.740.000347
ORF3a166S166LtCatTa33AY.90.000203
ORF3a166S166LtCatTa33B.1.1.4320.003797
ORF3a166S166LtCatTa33B.1.177.40.000633
ORF3a166S166LtCatTa33B.1.177.450.001144
ORF3a166S166LtCatTa33B.1.2340.000396
ORF3a166S166LtCatTa33B.1.3110.000824
ORF3a166S166LtCatTa33B.1.36.160.004274
ORF3a166S166LtCatTa33B.1.36.180.001261
ORF3a166S166LtCatTa33B.1.36.220.003623
ORF3a166S166LtCatTa33B.1.4000.001287
ORF3a166S166LtCatTa33B.1.5820.001472
ORF3a166S166LtCatTa33C.330.176471
ORF3a166S166LtCatTa33C.370.000348
ORF3a166S166LtCatTa33Q.40.001364
ORF3a166S166LtCatTa22A0.000774
ORF3a166S166LtCatTa22A.2.50.000998
ORF3a166S166LtCatTa22AY.1160.000574
ORF3a166S166LtCatTa22AY.120.10.000642
ORF3a166S166LtCatTa22AY.130.000322
ORF3a166S166LtCatTa22AY.240.000862
ORF3a166S166LtCatTa22AY.340.000194
ORF3a166S166LtCatTa22AY.360.000296
ORF3a166S166LtCatTa22AY.46.20.001271
ORF3a166S166LtCatTa22AY.750.000112
ORF3a166S166LtCatTa22B.1.1.10.000653
ORF3a166S166LtCatTa22B.1.1.1530.002191
ORF3a166S166LtCatTa22B.1.1.1920.004619
ORF3a166S166LtCatTa22B.1.1.2160.001781
ORF3a166S166LtCatTa22B.1.1.2180.015385
ORF3a166S166LtCatTa22B.1.1.3040.005618
ORF3a166S166LtCatTa22B.1.177.150.001262
ORF3a166S166LtCatTa22B.1.177.570.000562
ORF3a166S166LtCatTa22B.1.177.60.001953
ORF3a166S166LtCatTa22B.1.2210.000142
ORF3a166S166LtCatTa22B.1.3980.005952
ORF3a166S166LtCatTa22B.1.4040.002604
ORF3a166S166LtCatTa22B.1.4680.011429
ORF3a166S166LtCatTa22B.1.6090.000959
ORF3a166S166LtCatTa22B.1.6230.001073
ORF3a166S166LtCatTa22B.1.80.003945
ORF3a166S166LtCatTa22B.40.004415
ORF3a166S166LtCatTa22B.60.00182
ORF3a166S166LtCatTa22C.260.014706
ORF3a166S166LtCatTa22Q.10.000253
ORF3a166S166LtCatTa22Q.30.00029
ORF3a166S166LtCatTa11A.10.000282
ORF3a166S166LtCatTa11A.270.001656
ORF3a166S166LtCatTa11AY.10.000396
ORF3a166S166LtCatTa11AY.1090.00074
ORF3a166S166LtCatTa11AY.1100.000113
ORF3a166S166LtCatTa11AY.1110.000183
ORF3a166S166LtCatTa11AY.1130.000142
ORF3a166S166LtCatTa11AY.1190.000035
ORF3a166S166LtCatTa11AY.190.00114
ORF3a166S166LtCatTa11AY.4.2.10.000149
ORF3a166S166LtCatTa11AY.46.50.000198
ORF3a166S166LtCatTa11AY.5.40.000277
ORF3a166S166LtCatTa11AY.560.001605
ORF3a166S166LtCatTa11AY.580.000907
ORF3a166S166LtCatTa11AY.630.000387
ORF3a166S166LtCatTa11AY.650.000533
ORF3a166S166LtCatTa11AY.680.000274
ORF3a166S166LtCatTa11AY.7.10.000113
ORF3a166S166LtCatTa11AY.710.000475
ORF3a166S166LtCatTa11AY.75.10.00018
ORF3a166S166LtCatTa11AY.80.000606
ORF3a166S166LtCatTa11AY.840.000437
ORF3a166S166LtCatTa11AY.920.000287
ORF3a166S166LtCatTa11AY.930.000273
ORF3a166S166LtCatTa11AY.940.000443
ORF3a166S166LtCatTa11AY.99.20.000092
ORF3a166S166LtCatTa11B.1.1.1380.006061
ORF3a166S166LtCatTa11B.1.1.1570.000913
ORF3a166S166LtCatTa11B.1.1.1770.019231
ORF3a166S166LtCatTa11B.1.1.2070.001182
ORF3a166S166LtCatTa11B.1.1.2630.001558
ORF3a166S166LtCatTa11B.1.1.2690.001353
ORF3a166S166LtCatTa11B.1.1.2970.002237
ORF3a166S166LtCatTa11B.1.1.3060.000438
ORF3a166S166LtCatTa11B.1.1.3150.008475
ORF3a166S166LtCatTa11B.1.1.3200.018182
ORF3a166S166LtCatTa11B.1.1.3220.008772
ORF3a166S166LtCatTa11B.1.1.3370.003597
ORF3a166S166LtCatTa11B.1.1.3510.002793
ORF3a166S166LtCatTa11B.1.1.3590.027778
ORF3a166S166LtCatTa11B.1.1.4190.007407
ORF3a166S166LtCatTa11B.1.1.4420.018519
ORF3a166S166LtCatTa11B.1.1.500.000679
ORF3a166S166LtCatTa11B.1.1110.001175
ORF3a166S166LtCatTa11B.1.1470.000756
ORF3a166S166LtCatTa11B.1.1490.003425
ORF3a166S166LtCatTa11B.1.160.200.008929
ORF3a166S166LtCatTa11B.1.160.300.002976
ORF3a166S166LtCatTa11B.1.160.320.004292
ORF3a166S166LtCatTa11B.1.177.440.000519
ORF3a166S166LtCatTa11B.1.177.560.000668
ORF3a166S166LtCatTa11B.1.177.750.001041
ORF3a166S166LtCatTa11B.1.2220.001692
ORF3a166S166LtCatTa11B.1.2230.002778
ORF3a166S166LtCatTa11B.1.258.170.000104
ORF3a166S166LtCatTa11B.1.2600.003344
ORF3a166S166LtCatTa11B.1.3090.047619
ORF3a166S166LtCatTa11B.1.3200.001245
ORF3a166S166LtCatTa11B.1.3460.001311
ORF3a166S166LtCatTa11B.1.351.20.000303
ORF3a166S166LtCatTa11B.1.351.30.000876
ORF3a166S166LtCatTa11B.1.36.170.000494
ORF3a166S166LtCatTa11B.1.36.190.009259
ORF3a166S166LtCatTa11B.1.36.310.001751
ORF3a166S166LtCatTa11B.1.36.380.001642
ORF3a166S166LtCatTa11B.1.3670.000792
ORF3a166S166LtCatTa11B.1.3910.001127
ORF3a166S166LtCatTa11B.1.3960.000706
ORF3a166S166LtCatTa11B.1.4030.003268
ORF3a166S166LtCatTa11B.1.4130.004255
ORF3a166S166LtCatTa11B.1.4220.000812
ORF3a166S166LtCatTa11B.1.438.10.000107
ORF3a166S166LtCatTa11B.1.4520.013699
ORF3a166S166LtCatTa11B.1.4530.003236
ORF3a166S166LtCatTa11B.1.466.20.000391
ORF3a166S166LtCatTa11B.1.4710.002732
ORF3a166S166LtCatTa11B.1.4730.019231
ORF3a166S166LtCatTa11B.1.4970.000315
ORF3a166S166LtCatTa11B.1.5090.000866
ORF3a166S166LtCatTa11B.1.5650.00081
ORF3a166S166LtCatTa11B.1.5750.000303
ORF3a166S166LtCatTa11B.1.5870.001898
ORF3a166S166LtCatTa11B.1.5880.00091
ORF3a166S166LtCatTa11B.1.5950.000261
ORF3a166S166LtCatTa11B.1.595.10.005848
ORF3a166S166LtCatTa11B.1.6050.005952
ORF3a166S166LtCatTa11B.1.6120.002653
ORF3a166S166LtCatTa11B.1.6200.000946
ORF3a166S166LtCatTa11B.1.621.10.000506
ORF3a166S166LtCatTa11B.1.6280.000352
ORF3a166S166LtCatTa11B.1.780.008547
ORF3a166S166LtCatTa11B.1.9.50.005682
ORF3a166S166LtCatTa11B.390.002331
ORF3a166S166LtCatTa11B.4.50.011905
ORF3a166S166LtCatTa11C.360.000911
ORF3a166S166LtCatTa11L.10.001905
ORF3a166S166LtCatTa11P.1.110.010204
ORF3a166S166LtCatTa11P.40.003802

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.