CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF3a : Mut = L53F

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF3a53L53FnonsynCttTtt10395103920.99971125549-25551
ORF3a53L53FnonsynCtTTtC1039530.000288625549-25551

Details of the mutation L53F within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF3a53L53FCttTtt1039210395All0.001988
ORF3a53L53FCtTTtC310395All0.000001
ORF3a53L53FCttTtt16341634AY.10.646617
ORF3a53L53FCttTtt14461446B.1.1.70.001294
ORF3a53L53FCttTtt731731B.1.617.20.002753
ORF3a53L53FCttTtt719719AY.40.001119
ORF3a53L53FCttTtt605605B.10.005542
ORF3a53L53FCttTtt440440AY.250.002647
ORF3a53L53FCttTtt285285AY.120.090076
ORF3a53L53FCttTtt283283AY.430.001254
ORF3a53L53FCttTtt281282AY.440.00171
ORF3a53L53FCtTTtC1282AY.440.000006
ORF3a53L53FCttTtt233233AY.50.004811
ORF3a53L53FCttTtt204204AY.30.002029
ORF3a53L53FCttTtt181181B.1.20.001594
ORF3a53L53FCttTtt168168B.1.1770.002212
ORF3a53L53FCttTtt167167AY.1030.001037
ORF3a53L53FCttTtt156156AY.34.10.079551
ORF3a53L53FCttTtt147147AY.1020.003898
ORF3a53L53FCttTtt102102AY.360.015118
ORF3a53L53FCttTtt9898AY.99.20.009031
ORF3a53L53FCttTtt9494B.1.10.001705
ORF3a53L53FCttTtt9090AY.4.20.001952
ORF3a53L53FCttTtt7777AY.390.001903
ORF3a53L53FCttTtt7575B.1.1600.002339
ORF3a53L53FCttTtt7575P.10.001182
ORF3a53L53FCttTtt6969AY.200.002682
ORF3a53L53FCttTtt6161AY.1170.005156
ORF3a53L53FCttTtt5959AY.280.111531
ORF3a53L53FCttTtt5656B.1.5260.001316
ORF3a53L53FCttTtt5353AY.290.000836
ORF3a53L53FCttTtt5252B.1.3370.290503
ORF3a53L53FCttTtt4545AY.690.0084
ORF3a53L53FCttTtt4444AY.260.001246
ORF3a53L53FCttTtt4242AY.46.60.003033
ORF3a53L53FCttTtt4242AY.990.044071
ORF3a53L53FCttTtt4242B.1.110.30.030172
ORF3a53L53FCttTtt3535B.1.2430.002435
ORF3a53L53FCttTtt3131B.1.4000.013299
ORF3a53L53FCttTtt3030AY.1180.001879
ORF3a53L53FCttTtt3030AY.270.001942
ORF3a53L53FCttTtt3030B.1.1.5190.001191
ORF3a53L53FCttTtt2929AY.700.006047
ORF3a53L53FCttTtt2828B.1.2190.264151
ORF3a53L53FCttTtt2727AY.1130.003845
ORF3a53L53FCttTtt2727AY.1200.001004
ORF3a53L53FCttTtt2525AY.1000.00115
ORF3a53L53FCttTtt2424AY.1190.000847
ORF3a53L53FCttTtt2424AY.750.001345
ORF3a53L53FCttTtt2424B.1.4290.000565
ORF3a53L53FCttTtt2222AY.1060.007368
ORF3a53L53FCttTtt2022B.1.2580.001331
ORF3a53L53FCtTTtC222B.1.2580.000133
ORF3a53L53FCttTtt2222C.370.002553
ORF3a53L53FCttTtt2121AY.330.001402
ORF3a53L53FCttTtt2121AY.470.000653
ORF3a53L53FCttTtt2020AY.120.20.025707
ORF3a53L53FCttTtt2020B.1.177.570.00562
ORF3a53L53FCttTtt1818AY.640.010714
ORF3a53L53FCttTtt1717AY.460.001769
ORF3a53L53FCttTtt1717AY.980.001343
ORF3a53L53FCttTtt1717B.6.10.447368
ORF3a53L53FCttTtt1616AY.450.001947
ORF3a53L53FCttTtt1616AY.60.000658
ORF3a53L53FCttTtt1616B.1.1.3260.028169
ORF3a53L53FCttTtt1616B.1.4270.000808
ORF3a53L53FCttTtt1616B.1.6370.001169
ORF3a53L53FCttTtt1515B.1.1.4340.005228
ORF3a53L53FCttTtt1515B.1.3510.000446
ORF3a53L53FCttTtt1414AY.230.000976
ORF3a53L53FCttTtt1313AY.1110.002381
ORF3a53L53FCttTtt1313AY.130.002093
ORF3a53L53FCttTtt1313B.1.4560.042484
ORF3a53L53FCttTtt1313C.350.010062
ORF3a53L53FCttTtt1212B.1.2210.000852
ORF3a53L53FCttTtt1212B.1.3960.008469
ORF3a53L53FCttTtt1111A.290.058511
ORF3a53L53FCttTtt1111AY.620.004793
ORF3a53L53FCttTtt1111AY.75.10.001983
ORF3a53L53FCttTtt1111AY.9.10.000921
ORF3a53L53FCttTtt1111B.1.1.2140.00061
ORF3a53L53FCttTtt1111B.1.2180.056701
ORF3a53L53FCttTtt1111P.1.60.021401
ORF3a53L53FCttTtt1010A.170.909091
ORF3a53L53FCttTtt1010AE.80.00489
ORF3a53L53FCttTtt1010AY.3.10.000853
ORF3a53L53FCttTtt1010B.1.360.001459
ORF3a53L53FCttTtt1010B.1.5250.001132
ORF3a53L53FCttTtt99AY.530.002588
ORF3a53L53FCttTtt99AY.98.10.000436
ORF3a53L53FCttTtt99B.1.258.110.003567
ORF3a53L53FCttTtt99B.1.6210.000797
ORF3a53L53FCttTtt99R.10.00081
ORF3a53L53FCttTtt88AY.1010.003923
ORF3a53L53FCttTtt88AY.4.2.10.001192
ORF3a53L53FCttTtt88B.1.438.10.000858
ORF3a53L53FCttTtt77AY.370.002212
ORF3a53L53FCttTtt77AY.39.10.000277
ORF3a53L53FCttTtt77AY.420.000282
ORF3a53L53FCttTtt77AY.740.00081
ORF3a53L53FCttTtt77AY.840.003062
ORF3a53L53FCttTtt77B0.000895
ORF3a53L53FCttTtt77B.1.1.1130.048951
ORF3a53L53FCttTtt77B.1.1.2220.001428
ORF3a53L53FCttTtt77B.1.1.280.002179
ORF3a53L53FCttTtt77B.1.1.2840.000752
ORF3a53L53FCttTtt77B.1.160.320.030043
ORF3a53L53FCttTtt77B.1.617.10.000903
ORF3a53L53FCttTtt77D.20.000525
ORF3a53L53FCttTtt77P.1.150.001626
ORF3a53L53FCttTtt66AY.710.00285
ORF3a53L53FCttTtt66AY.9.20.00022
ORF3a53L53FCttTtt66AY.920.001724
ORF3a53L53FCttTtt66AY.930.001638
ORF3a53L53FCttTtt66B.1.1.1890.009077
ORF3a53L53FCttTtt66B.1.177.430.008863
ORF3a53L53FCttTtt66B.1.2400.001293
ORF3a53L53FCttTtt66B.1.36.290.003104
ORF3a53L53FCttTtt66B.1.4090.004687
ORF3a53L53FCttTtt66P.60.018868
ORF3a53L53FCttTtt66Q.10.000758
ORF3a53L53FCttTtt55AY.1210.000677
ORF3a53L53FCttTtt55AY.140.00044
ORF3a53L53FCttTtt55AY.300.001979
ORF3a53L53FCttTtt55AY.340.000485
ORF3a53L53FCttTtt55AY.380.002496
ORF3a53L53FCttTtt55AY.400.004822
ORF3a53L53FCttTtt55AY.540.000477
ORF3a53L53FCttTtt55AY.610.000524
ORF3a53L53FCttTtt55B.1.1.3850.022321
ORF3a53L53FCttTtt55B.1.5750.001517
ORF3a53L53FCttTtt55B.1.5960.000436
ORF3a53L53FCttTtt55B.1.5970.023148
ORF3a53L53FCttTtt55Q.30.000725
ORF3a53L53FCttTtt44AY.1100.000451
ORF3a53L53FCttTtt44AY.4.50.00043
ORF3a53L53FCttTtt44AY.5.40.001107
ORF3a53L53FCttTtt44AY.7.10.000451
ORF3a53L53FCttTtt44AY.90.00027
ORF3a53L53FCttTtt44AY.99.10.006211
ORF3a53L53FCttTtt44B.1.1110.0047
ORF3a53L53FCttTtt44B.1.36.80.004
ORF3a53L53FCttTtt44B.1.4280.004082
ORF3a53L53FCttTtt44B.1.5580.018265
ORF3a53L53FCttTtt44B.1.6090.001918
ORF3a53L53FCttTtt44P.1.140.000191
ORF3a53L53FCttTtt330.166667
ORF3a53L53FCttTtt33A.50.005769
ORF3a53L53FCttTtt33AY.190.003421
ORF3a53L53FCttTtt33AY.240.001293
ORF3a53L53FCttTtt33AY.410.000882
ORF3a53L53FCttTtt33AY.46.50.000595
ORF3a53L53FCttTtt33AY.5.30.001012
ORF3a53L53FCttTtt33AY.500.002398
ORF3a53L53FCttTtt33AY.850.001282
ORF3a53L53FCttTtt33AY.860.00249
ORF3a53L53FCttTtt33AY.900.002053
ORF3a53L53FCttTtt33B.1.1.2160.002671
ORF3a53L53FCttTtt33B.1.1.250.001706
ORF3a53L53FCttTtt33B.1.1.2750.033708
ORF3a53L53FCttTtt33B.1.1.2770.002276
ORF3a53L53FCttTtt33B.1.1.3480.002389
ORF3a53L53FCttTtt33B.1.177.70.000495
ORF3a53L53FCttTtt33B.1.2320.001612
ORF3a53L53FCttTtt33B.1.3140.022556
ORF3a53L53FCttTtt33B.1.36.10.003421
ORF3a53L53FCttTtt33B.1.466.20.001174
ORF3a53L53FCttTtt33B.1.5240.004219
ORF3a53L53FCttTtt33B.1.6280.001057
ORF3a53L53FCttTtt33P.1.170.000485
ORF3a53L53FCttTtt33P.40.011407
ORF3a53L53FCttTtt22A.10.000564
ORF3a53L53FCttTtt22AY.120.10.000642
ORF3a53L53FCttTtt22AY.160.000759
ORF3a53L53FCttTtt22AY.46.10.002053
ORF3a53L53FCttTtt22AY.510.001818
ORF3a53L53FCttTtt22AY.660.002139
ORF3a53L53FCttTtt22AY.670.000929
ORF3a53L53FCttTtt22AY.680.000547
ORF3a53L53FCttTtt22AY.70.000392
ORF3a53L53FCttTtt22AY.780.003082
ORF3a53L53FCttTtt22AY.820.002714
ORF3a53L53FCttTtt22AY.910.001461
ORF3a53L53FCttTtt22B.1.1.10.000653
ORF3a53L53FCttTtt22B.1.1.1200.066667
ORF3a53L53FCttTtt22B.1.1.1590.009346
ORF3a53L53FCttTtt22B.1.1.1630.015267
ORF3a53L53FCttTtt22B.1.1.2820.023256
ORF3a53L53FCttTtt22B.1.1.3060.000877
ORF3a53L53FCttTtt22B.1.1.3170.000823
ORF3a53L53FCttTtt22B.1.1.3180.000604
ORF3a53L53FCttTtt22B.1.1.330.000842
ORF3a53L53FCttTtt22B.1.1.3690.000892
ORF3a53L53FCttTtt22B.1.1.3720.001377
ORF3a53L53FCttTtt22B.1.1.4480.004065
ORF3a53L53FCttTtt22B.1.1.5170.013605
ORF3a53L53FCttTtt22B.1.1.5260.007092
ORF3a53L53FCttTtt22B.1.1.700.000682
ORF3a53L53FCttTtt22B.1.177.160.001329
ORF3a53L53FCttTtt22B.1.177.440.001038
ORF3a53L53FCttTtt22B.1.177.560.001335
ORF3a53L53FCttTtt22B.1.177.860.000367
ORF3a53L53FCttTtt22B.1.177.870.001456
ORF3a53L53FCttTtt22B.1.2340.000264
ORF3a53L53FCttTtt22B.1.2370.00995
ORF3a53L53FCttTtt22B.1.3620.003082
ORF3a53L53FCttTtt22B.1.3690.00057
ORF3a53L53FCttTtt22B.1.4160.002538
ORF3a53L53FCttTtt22B.1.5110.068966
ORF3a53L53FCttTtt22B.1.5170.000854
ORF3a53L53FCttTtt22B.1.5270.007407
ORF3a53L53FCttTtt22B.1.5680.002222
ORF3a53L53FCttTtt22B.1.5950.000522
ORF3a53L53FCttTtt22B.400.000729
ORF3a53L53FCttTtt22B.60.00182
ORF3a53L53FCttTtt22C.20.032258
ORF3a53L53FCttTtt22C.36.30.001134
ORF3a53L53FCttTtt22P.1.70.000639
ORF3a53L53FCttTtt22P.20.000373
ORF3a53L53FCttTtt22P.30.00319
ORF3a53L53FCttTtt11A.20.000662
ORF3a53L53FCttTtt11A.23.10.000704
ORF3a53L53FCttTtt11AT.10.005128
ORF3a53L53FCttTtt11AU.10.001266
ORF3a53L53FCttTtt11AY.1050.000643
ORF3a53L53FCttTtt11AY.1090.00074
ORF3a53L53FCttTtt11AY.1140.000231
ORF3a53L53FCttTtt11AY.1160.000287
ORF3a53L53FCttTtt11AY.120.2.10.000498
ORF3a53L53FCttTtt11AY.220.002092
ORF3a53L53FCttTtt11AY.23.10.000417
ORF3a53L53FCttTtt11AY.29.10.000221
ORF3a53L53FCttTtt11AY.320.000532
ORF3a53L53FCttTtt11AY.350.000233
ORF3a53L53FCttTtt11AY.39.1.10.000725
ORF3a53L53FCttTtt11AY.4.30.000842
ORF3a53L53FCttTtt11AY.46.30.000934
ORF3a53L53FCttTtt11AY.46.40.000165
ORF3a53L53FCttTtt11AY.560.001605
ORF3a53L53FCttTtt11AY.590.00053
ORF3a53L53FCttTtt11AY.720.001361
ORF3a53L53FCttTtt11AY.730.000665
ORF3a53L53FCttTtt11AY.800.001129
ORF3a53L53FCttTtt11AY.870.000833
ORF3a53L53FCttTtt11AY.880.000884
ORF3a53L53FCttTtt11AY.960.002075
ORF3a53L53FCttTtt11AZ.60.008403
ORF3a53L53FCttTtt11B.1.1.1290.009174
ORF3a53L53FCttTtt11B.1.1.1410.002012
ORF3a53L53FCttTtt11B.1.1.1740.003378
ORF3a53L53FCttTtt11B.1.1.1760.000439
ORF3a53L53FCttTtt11B.1.1.1780.041667
ORF3a53L53FCttTtt11B.1.1.2190.005
ORF3a53L53FCttTtt11B.1.1.2280.003049
ORF3a53L53FCttTtt11B.1.1.2540.011236
ORF3a53L53FCttTtt11B.1.1.2910.000742
ORF3a53L53FCttTtt11B.1.1.3010.001179
ORF3a53L53FCttTtt11B.1.1.3110.000358
ORF3a53L53FCttTtt11B.1.1.340.013158
ORF3a53L53FCttTtt11B.1.1.370.000193
ORF3a53L53FCttTtt11B.1.1.3760.005952
ORF3a53L53FCttTtt11B.1.1.4090.002833
ORF3a53L53FCttTtt11B.1.1.4130.006897
ORF3a53L53FCttTtt11B.1.1.4670.019231
ORF3a53L53FCttTtt11B.1.1.480.002874
ORF3a53L53FCttTtt11B.1.1.5180.006329
ORF3a53L53FCttTtt11B.1.1.5230.001563
ORF3a53L53FCttTtt11B.1.1040.00369
ORF3a53L53FCttTtt11B.1.1280.000635
ORF3a53L53FCttTtt11B.1.1390.000733
ORF3a53L53FCttTtt11B.1.1570.002985
ORF3a53L53FCttTtt11B.1.177.120.000152
ORF3a53L53FCttTtt11B.1.177.150.000631
ORF3a53L53FCttTtt11B.1.177.210.000076
ORF3a53L53FCttTtt11B.1.177.420.000894
ORF3a53L53FCttTtt11B.1.177.520.001757
ORF3a53L53FCttTtt11B.1.177.530.002392
ORF3a53L53FCttTtt11B.1.177.580.001332
ORF3a53L53FCttTtt11B.1.177.600.000218
ORF3a53L53FCttTtt11B.1.177.620.001192
ORF3a53L53FCttTtt11B.1.177.630.002703
ORF3a53L53FCttTtt11B.1.177.650.000665
ORF3a53L53FCttTtt11B.1.177.690.001484
ORF3a53L53FCttTtt11B.1.177.730.000566
ORF3a53L53FCttTtt11B.1.177.810.000189
ORF3a53L53FCttTtt11B.1.2100.002132
ORF3a53L53FCttTtt11B.1.2140.003663
ORF3a53L53FCttTtt11B.1.2360.002053
ORF3a53L53FCttTtt11B.1.2520.006623
ORF3a53L53FCttTtt11B.1.258.170.000104
ORF3a53L53FCttTtt11B.1.2910.019231
ORF3a53L53FCttTtt11B.1.30.002618
ORF3a53L53FCttTtt11B.1.3200.001245
ORF3a53L53FCttTtt11B.1.3240.001605
ORF3a53L53FCttTtt11B.1.3460.001311
ORF3a53L53FCttTtt11B.1.351.30.000876
ORF3a53L53FCttTtt11B.1.36.100.004785
ORF3a53L53FCttTtt11B.1.36.170.000494
ORF3a53L53FCttTtt11B.1.36.380.001642
ORF3a53L53FCttTtt11B.1.3610.001289
ORF3a53L53FCttTtt11B.1.3980.002976
ORF3a53L53FCttTtt11B.1.4030.003268
ORF3a53L53FCttTtt11B.1.4080.00369
ORF3a53L53FCttTtt11B.1.4110.003704
ORF3a53L53FCttTtt11B.1.4620.007246
ORF3a53L53FCttTtt11B.1.4690.00361
ORF3a53L53FCttTtt11B.1.5380.008065
ORF3a53L53FCttTtt11B.1.5390.017544
ORF3a53L53FCttTtt11B.1.5610.000397
ORF3a53L53FCttTtt11B.1.5770.000687
ORF3a53L53FCttTtt11B.1.5820.000491
ORF3a53L53FCttTtt11B.1.5940.03125
ORF3a53L53FCttTtt11B.1.6000.005848
ORF3a53L53FCttTtt11B.1.6120.002653
ORF3a53L53FCttTtt11B.1.6200.000946
ORF3a53L53FCttTtt11B.1.621.10.000506
ORF3a53L53FCttTtt11B.1.6230.000536
ORF3a53L53FCttTtt11B.1.6250.002353
ORF3a53L53FCttTtt11B.1.6310.003367
ORF3a53L53FCttTtt11B.1.90.006173
ORF3a53L53FCttTtt11B.1.9.50.005682
ORF3a53L53FCttTtt11B.6.80.008264
ORF3a53L53FCttTtt11C.130.025641
ORF3a53L53FCttTtt11C.140.004329
ORF3a53L53FCttTtt11C.220.071429
ORF3a53L53FCttTtt11L.30.003546
ORF3a53L53FCttTtt11N.90.005952
ORF3a53L53FCttTtt11P.1.100.000269
ORF3a53L53FCttTtt11P.1.120.000484
ORF3a53L53FCttTtt11Q.80.000165
ORF3a53L53FCttTtt11W.10.008696

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.