CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF3a : Mut = L219F

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF3a219L219FnonsynttGttT263726330.99848326047-26049
ORF3a219L219FnonsynttGttC263740.0015168826047-26049

Details of the mutation L219F within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF3a219L219FttGttT26332637All0.000504
ORF3a219L219FttGttC42637All0.000001
ORF3a219L219FttGttT15801580AY.260.04473
ORF3a219L219FttGttT217217B.1.617.20.000817
ORF3a219L219FttGttT185185B.1.1.70.000166
ORF3a219L219FttGttT144144B.1.1.370.027772
ORF3a219L219FttGttT6868B.1.10.001234
ORF3a219L219FttGttT5858B.1.20.000511
ORF3a219L219FttGttT3030P.1.40.029297
ORF3a219L219FttGttT2828AY.430.000124
ORF3a219L219FttGttT2626B.1.1770.000342
ORF3a219L219FttGttT2626B.1.5260.000611
ORF3a219L219FttGttT2121AY.390.000519
ORF3a219L219FttGttT1819AY.1030.000112
ORF3a219L219FttGttC119AY.1030.000006
ORF3a219L219FttGttT1919AY.40.00003
ORF3a219L219FttGttT1515B.1.1600.000468
ORF3a219L219FttGttT1414AY.1130.001993
ORF3a219L219FttGttT1212AY.250.000072
ORF3a219L219FttGttT1212B.10.00011
ORF3a219L219FttGttT1111AY.4.20.000239
ORF3a219L219FttGttT1111AY.440.000067
ORF3a219L219FttGttT99AY.9.20.000331
ORF3a219L219FttGttT88AY.1140.001849
ORF3a219L219FttGttT66B.1.4290.000141
ORF3a219L219FttGttT66P.10.000095
ORF3a219L219FttGttT55AY.140.00044
ORF3a219L219FttGttT55AY.450.000608
ORF3a219L219FttGttT55AY.46.40.000823
ORF3a219L219FttGttT55AY.50.000103
ORF3a219L219FttGttT55AY.610.000524
ORF3a219L219FttGttT44AY.1000.000184
ORF3a219L219FttGttT44B.1.177.870.002911
ORF3a219L219FttGttT44B.1.36.290.002069
ORF3a219L219FttGttT44B.1.6370.000292
ORF3a219L219FttGttT33AY.1020.00008
ORF3a219L219FttGttT33AY.75.10.000541
ORF3a219L219FttGttT33B.1.1.4190.022222
ORF3a219L219FttGttT33B.1.4740.005703
ORF3a219L219FttGttT22AY.1160.000574
ORF3a219L219FttGttT22AY.1210.000271
ORF3a219L219FttGttT22AY.230.000139
ORF3a219L219FttGttC22AY.30.00002
ORF3a219L219FttGttT22AY.980.000158
ORF3a219L219FttGttT22B.1.1.2030.033898
ORF3a219L219FttGttT22B.1.1.250.001137
ORF3a219L219FttGttT22B.1.1.500.001358
ORF3a219L219FttGttT22B.1.4250.005988
ORF3a219L219FttGttT22Q.20.001227
ORF3a219L219FttGttT22Q.80.00033
ORF3a219L219FttGttT11AY.10.000396
ORF3a219L219FttGttT11AY.100.00053
ORF3a219L219FttGttT11AY.1110.000183
ORF3a219L219FttGttT11AY.1180.000063
ORF3a219L219FttGttT11AY.16.10.00047
ORF3a219L219FttGttT11AY.200.000039
ORF3a219L219FttGttT11AY.240.000431
ORF3a219L219FttGttT11AY.300.000396
ORF3a219L219FttGttT11AY.420.00004
ORF3a219L219FttGttT11AY.46.20.000635
ORF3a219L219FttGttT11AY.590.00053
ORF3a219L219FttGttT11AY.670.000464
ORF3a219L219FttGttT11AY.710.000475
ORF3a219L219FttGttT11AY.780.001541
ORF3a219L219FttGttT11AY.870.000833
ORF3a219L219FttGttT11AY.98.10.000048
ORF3a219L219FttGttT11AY.99.20.000092
ORF3a219L219FttGttT11AZ.50.003509
ORF3a219L219FttGttT11B.1.1.100.001115
ORF3a219L219FttGttT11B.1.1.1340.011364
ORF3a219L219FttGttT11B.1.1.160.055556
ORF3a219L219FttGttT11B.1.1.1760.000439
ORF3a219L219FttGttT11B.1.1.2140.000055
ORF3a219L219FttGttT11B.1.1.2160.00089
ORF3a219L219FttGttT11B.1.1.2220.000204
ORF3a219L219FttGttT11B.1.1.280.000311
ORF3a219L219FttGttC11B.1.1.3170.000412
ORF3a219L219FttGttT11B.1.1.3440.010753
ORF3a219L219FttGttT11B.1.177.40.000211
ORF3a219L219FttGttT11B.1.2210.000071
ORF3a219L219FttGttT11B.1.351.20.000303
ORF3a219L219FttGttT11B.1.4330.003195
ORF3a219L219FttGttT11B.1.466.20.000391
ORF3a219L219FttGttT11B.1.5610.000397
ORF3a219L219FttGttT11B.1.6210.000089
ORF3a219L219FttGttT11B.1.6280.000352
ORF3a219L219FttGttT11C.40.01

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

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