CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF3a : Mut = L129F

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF3a129L129FnonsynCttTtt33393339125777-25779

Details of the mutation L129F within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF3a129L129FCttTtt33393339All0.000639
ORF3a129L129FCttTtt972972AY.1200.036138
ORF3a129L129FCttTtt357357B.1.1.1700.445137
ORF3a129L129FCttTtt297297AY.40.000462
ORF3a129L129FCttTtt250250AY.440.001522
ORF3a129L129FCttTtt198198B.1.1.70.000177
ORF3a129L129FCttTtt172172B.1.3060.982857
ORF3a129L129FCttTtt153153B.10.001401
ORF3a129L129FCttTtt141141B.1.617.20.000531
ORF3a129L129FCttTtt7373B.1.5750.022148
ORF3a129L129FCttTtt6565AY.50.001342
ORF3a129L129FCttTtt4141B.1.1600.001279
ORF3a129L129FCttTtt3838B.1.10.000689
ORF3a129L129FCttTtt3434AY.30.000338
ORF3a129L129FCttTtt2929AY.250.000174
ORF3a129L129FCttTtt2121B.1.20.000185
ORF3a129L129FCttTtt2020B.1.2320.010747
ORF3a129L129FCttTtt1919AY.90.001284
ORF3a129L129FCttTtt1919P.1.140.000908
ORF3a129L129FCttTtt1515AY.290.000237
ORF3a129L129FCttTtt1515D.20.001126
ORF3a129L129FCttTtt1414AY.4.20.000304
ORF3a129L129FCttTtt1414B.1.6230.007511
ORF3a129L129FCttTtt1414P.10.000221
ORF3a129L129FCttTtt1111AY.1030.000068
ORF3a129L129FCttTtt1111B.1.1770.000145
ORF3a129L129FCttTtt1010AY.1000.00046
ORF3a129L129FCttTtt1010AY.390.000247
ORF3a129L129FCttTtt99P.20.00168
ORF3a129L129FCttTtt88A0.003096
ORF3a129L129FCttTtt88AY.430.000035
ORF3a129L129FCttTtt88B.1.4290.000188
ORF3a129L129FCttTtt88B.1.6090.003835
ORF3a129L129FCttTtt88C.370.000929
ORF3a129L129FCttTtt77AY.1020.000186
ORF3a129L129FCttTtt77B.1.1.3700.088608
ORF3a129L129FCttTtt77B.1.4270.000353
ORF3a129L129FCttTtt77B.1.5170.002989
ORF3a129L129FCttTtt77R.10.00063
ORF3a129L129FCttTtt66AY.330.000401
ORF3a129L129FCttTtt66AY.360.000889
ORF3a129L129FCttTtt66AY.46.60.000433
ORF3a129L129FCttTtt66AZ.20.004926
ORF3a129L129FCttTtt66B.1.1.3180.001811
ORF3a129L129FCttTtt66B.1.2210.000426
ORF3a129L129FCttTtt66P.1.40.005859
ORF3a129L129FCttTtt55AY.120.20.006427
ORF3a129L129FCttTtt55B.1.1.2160.004452
ORF3a129L129FCttTtt55B.1.1.3890.030303
ORF3a129L129FCttTtt55B.1.5250.000566
ORF3a129L129FCttTtt44AY.590.002119
ORF3a129L129FCttTtt44AY.610.000419
ORF3a129L129FCttTtt44B.1.177.160.002658
ORF3a129L129FCttTtt44B.1.6210.000354
ORF3a129L129FCttTtt33AY.1050.001929
ORF3a129L129FCttTtt33AY.230.000209
ORF3a129L129FCttTtt33AY.39.10.000119
ORF3a129L129FCttTtt33AY.470.000093
ORF3a129L129FCttTtt33AY.540.000286
ORF3a129L129FCttTtt33AY.60.000123
ORF3a129L129FCttTtt33AY.7.10.000338
ORF3a129L129FCttTtt33AY.740.000347
ORF3a129L129FCttTtt33B.1.1.1890.004539
ORF3a129L129FCttTtt33B.1.1.4090.008499
ORF3a129L129FCttTtt33B.1.2430.000209
ORF3a129L129FCttTtt33B.1.5760.00272
ORF3a129L129FCttTtt33B.1.5960.000261
ORF3a129L129FCttTtt33P.1.150.000697
ORF3a129L129FCttTtt33Q.10.000379
ORF3a129L129FCttTtt22AY.116.10.000623
ORF3a129L129FCttTtt22AY.260.000057
ORF3a129L129FCttTtt22AY.3.10.000171
ORF3a129L129FCttTtt22AY.300.000791
ORF3a129L129FCttTtt22AY.75.10.000361
ORF3a129L129FCttTtt22AY.840.000875
ORF3a129L129FCttTtt22AY.980.000158
ORF3a129L129FCttTtt22B0.000256
ORF3a129L129FCttTtt22B.1.1.250.001137
ORF3a129L129FCttTtt22B.1.1.2980.001724
ORF3a129L129FCttTtt22B.1.1.460.008734
ORF3a129L129FCttTtt22B.1.1.500.001358
ORF3a129L129FCttTtt22B.1.2400.000431
ORF3a129L129FCttTtt22B.1.3240.00321
ORF3a129L129FCttTtt22B.1.3510.000059
ORF3a129L129FCttTtt22B.1.3560.003454
ORF3a129L129FCttTtt22B.1.36.290.001035
ORF3a129L129FCttTtt22B.1.4700.002809
ORF3a129L129FCttTtt22B.1.5610.000794
ORF3a129L129FCttTtt22B.1.6200.001892
ORF3a129L129FCttTtt11A.2.20.001689
ORF3a129L129FCttTtt11A.250.018182
ORF3a129L129FCttTtt11AA.10.007246
ORF3a129L129FCttTtt11AD.20.000219
ORF3a129L129FCttTtt11AY.1010.00049
ORF3a129L129FCttTtt11AY.1060.000335
ORF3a129L129FCttTtt11AY.1160.000287
ORF3a129L129FCttTtt11AY.120.000316
ORF3a129L129FCttTtt11AY.1210.000135
ORF3a129L129FCttTtt11AY.170.008197
ORF3a129L129FCttTtt11AY.20.000356
ORF3a129L129FCttTtt11AY.380.000499
ORF3a129L129FCttTtt11AY.4.40.000409
ORF3a129L129FCttTtt11AY.4.50.000107
ORF3a129L129FCttTtt11AY.420.00004
ORF3a129L129FCttTtt11AY.450.000122
ORF3a129L129FCttTtt11AY.460.000104
ORF3a129L129FCttTtt11AY.46.40.000165
ORF3a129L129FCttTtt11AY.490.003195
ORF3a129L129FCttTtt11AY.5.20.002463
ORF3a129L129FCttTtt11AY.650.000533
ORF3a129L129FCttTtt11AY.70.000196
ORF3a129L129FCttTtt11AY.770.001127
ORF3a129L129FCttTtt11AY.9.20.000037
ORF3a129L129FCttTtt11AY.900.000684
ORF3a129L129FCttTtt11AY.920.000287
ORF3a129L129FCttTtt11AY.960.002075
ORF3a129L129FCttTtt11AY.99.20.000092
ORF3a129L129FCttTtt11B.1.1.1640.005155
ORF3a129L129FCttTtt11B.1.1.2220.000204
ORF3a129L129FCttTtt11B.1.1.280.000311
ORF3a129L129FCttTtt11B.1.1.3170.000412
ORF3a129L129FCttTtt11B.1.1.3260.001761
ORF3a129L129FCttTtt11B.1.1.330.000421
ORF3a129L129FCttTtt11B.1.1.3690.000446
ORF3a129L129FCttTtt11B.1.1.370.000193
ORF3a129L129FCttTtt11B.1.1.3770.001381
ORF3a129L129FCttTtt11B.1.1.390.00051
ORF3a129L129FCttTtt11B.1.1.4020.011111
ORF3a129L129FCttTtt11B.1.1.4340.000349
ORF3a129L129FCttTtt11B.1.1.620.027027
ORF3a129L129FCttTtt11B.1.1100.004525
ORF3a129L129FCttTtt11B.1.177.320.00135
ORF3a129L129FCttTtt11B.1.177.440.000519
ORF3a129L129FCttTtt11B.1.177.730.000566
ORF3a129L129FCttTtt11B.1.177.860.000183
ORF3a129L129FCttTtt11B.1.2030.0625
ORF3a129L129FCttTtt11B.1.2060.000816
ORF3a129L129FCttTtt11B.1.2220.001692
ORF3a129L129FCttTtt11B.1.2340.000132
ORF3a129L129FCttTtt11B.1.2390.001221
ORF3a129L129FCttTtt11B.1.2410.000812
ORF3a129L129FCttTtt11B.1.2580.000067
ORF3a129L129FCttTtt11B.1.258.110.000396
ORF3a129L129FCttTtt11B.1.2820.014925
ORF3a129L129FCttTtt11B.1.3290.000608
ORF3a129L129FCttTtt11B.1.360.000146
ORF3a129L129FCttTtt11B.1.36.160.001425
ORF3a129L129FCttTtt11B.1.36.190.009259
ORF3a129L129FCttTtt11B.1.3670.000792
ORF3a129L129FCttTtt11B.1.3900.010638
ORF3a129L129FCttTtt11B.1.3970.004854
ORF3a129L129FCttTtt11B.1.4000.000429
ORF3a129L129FCttTtt11B.1.4170.028571
ORF3a129L129FCttTtt11B.1.4510.008197
ORF3a129L129FCttTtt11B.1.4530.003236
ORF3a129L129FCttTtt11B.1.4560.003268
ORF3a129L129FCttTtt11B.1.4670.04
ORF3a129L129FCttTtt11B.1.4680.005714
ORF3a129L129FCttTtt11B.1.5270.003704
ORF3a129L129FCttTtt11B.1.5680.001111
ORF3a129L129FCttTtt11B.1.617.10.000129
ORF3a129L129FCttTtt11B.1.6310.003367
ORF3a129L129FCttTtt11C.160.00106
ORF3a129L129FCttTtt11N.50.001767
ORF3a129L129FCttTtt11P.1.10.000318
ORF3a129L129FCttTtt11P.1.80.004785
ORF3a129L129FCttTtt11Q.40.000455
ORF3a129L129FCttTtt11Q.80.000165

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

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