CoV-GLUE Mutation

CoV-GLUE Mutation: ORF = ORF3a : Mut = K67V

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORF	CodonNum	Mut	ORF1abMut	MutType	RefCodon	MutCodon	AACount	CodonCount	CodonProp	Genome Position
ORF3a	67	K67V		nonsyn	AAG	GTA	5	2	0.4	25591-25593
ORF3a	67	K67V		nonsyn	AAG	GTT	5	2	0.4	25591-25593
ORF3a	67	K67V		nonsyn	AAg	GTg	5	1	0.2	25591-25593

Details of the mutation K67V within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORF	CodonNum	Mut	RefCodon	MutCodon	CodonCount	AACount	Lineage	LineageCodonProp
ORF3a	67	K67V	AAG	GTA	2	5	All	0
ORF3a	67	K67V	AAG	GTT	2	5	All	0
ORF3a	67	K67V	AAg	GTg	1	5	All	0
ORF3a	67	K67V	AAG	GTA	2	4		0.111111
ORF3a	67	K67V	AAG	GTT	2	4		0.111111
ORF3a	67	K67V	AAg	GTg	1	1	B.1.1.139	0.022727

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.