CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF3a : Mut = K21N

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF3a21K21NnonsynaaGaaT633657430.90640825453-25455
ORF3a21K21NnonsynaaGaaC63365930.093592225453-25455

Details of the mutation K21N within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF3a21K21NaaGaaT57436336All0.001098
ORF3a21K21NaaGaaC5936336All0.000113
ORF3a21K21NaaGaaT792804B.1.1.70.000709
ORF3a21K21NaaGaaC12804B.1.1.70.000011
ORF3a21K21NaaGaaT456481B.1.20.004015
ORF3a21K21NaaGaaC25481B.1.20.00022
ORF3a21K21NaaGaaT445451B.1.2210.03161
ORF3a21K21NaaGaaC6451B.1.2210.000426
ORF3a21K21NaaGaaC189374B.1.617.20.000712
ORF3a21K21NaaGaaT185374B.1.617.20.000697
ORF3a21K21NaaGaaT369369P.10.005813
ORF3a21K21NaaGaaT340340B.1.5701
ORF3a21K21NaaGaaT327333AY.440.00199
ORF3a21K21NaaGaaC6333AY.440.000037
ORF3a21K21NaaGaaT272280AY.40.000423
ORF3a21K21NaaGaaC8280AY.40.000012
ORF3a21K21NaaGaaC205216AY.1020.005435
ORF3a21K21NaaGaaT11216AY.1020.000292
ORF3a21K21NaaGaaT189189B.1.5260.004442
ORF3a21K21NaaGaaT178181B.10.00163
ORF3a21K21NaaGaaC3181B.10.000027
ORF3a21K21NaaGaaT166166B.1.1770.002186
ORF3a21K21NaaGaaT133144AY.430.000589
ORF3a21K21NaaGaaC11144AY.430.000049
ORF3a21K21NaaGaaT94104B.1.2580.006255
ORF3a21K21NaaGaaC10104B.1.2580.000665
ORF3a21K21NaaGaaT9091AY.1030.000559
ORF3a21K21NaaGaaC191AY.1030.000006
ORF3a21K21NaaGaaT8787B.1.1.540.26284
ORF3a21K21NaaGaaT7683B.1.4270.003838
ORF3a21K21NaaGaaC783B.1.4270.000353
ORF3a21K21NaaGaaT8080AY.290.001262
ORF3a21K21NaaGaaT6566AY.50.001342
ORF3a21K21NaaGaaC166AY.50.000021
ORF3a21K21NaaGaaT6163B.1.10.001107
ORF3a21K21NaaGaaC263B.1.10.000036
ORF3a21K21NaaGaaT6060B.1.258.170.006238
ORF3a21K21NaaGaaT5656AY.250.000337
ORF3a21K21NaaGaaT5555B.1.1.5190.002184
ORF3a21K21NaaGaaT5555P.1.140.002629
ORF3a21K21NaaGaaC2345AY.390.000568
ORF3a21K21NaaGaaT2245AY.390.000544
ORF3a21K21NaaGaaT4040B.1.5580.182648
ORF3a21K21NaaGaaT3838B.1.4990.039916
ORF3a21K21NaaGaaT3535B.1.3510.00104
ORF3a21K21NaaGaaT3535B.1.6210.003098
ORF3a21K21NaaGaaT3032AY.1170.002535
ORF3a21K21NaaGaaC232AY.1170.000169
ORF3a21K21NaaGaaT2525AY.1190.000883
ORF3a21K21NaaGaaT2425AY.950.018265
ORF3a21K21NaaGaaC125AY.950.000761
ORF3a21K21NaaGaaT2323AY.4.50.002472
ORF3a21K21NaaGaaT2121B.1.4290.000494
ORF3a21K21NaaGaaT2020AY.140.00176
ORF3a21K21NaaGaaT2020AY.880.017683
ORF3a21K21NaaGaaT2020B.1.6230.01073
ORF3a21K21NaaGaaT1919A.2.5.20.029874
ORF3a21K21NaaGaaT1919B.1.177.810.003597
ORF3a21K21NaaGaaC1418AY.1160.004015
ORF3a21K21NaaGaaT418AY.1160.001147
ORF3a21K21NaaGaaT1818B.1.5750.005461
ORF3a21K21NaaGaaT1616A.280.042328
ORF3a21K21NaaGaaT1616AY.30.000159
ORF3a21K21NaaGaaT1616C.370.001857
ORF3a21K21NaaGaaT815AY.1200.000297
ORF3a21K21NaaGaaC715AY.1200.00026
ORF3a21K21NaaGaaT1213AY.450.00146
ORF3a21K21NaaGaaC113AY.450.000122
ORF3a21K21NaaGaaC1313B.1.177.800.024857
ORF3a21K21NaaGaaT1212AZ.10.010408
ORF3a21K21NaaGaaT1212B.1.1.4320.01519
ORF3a21K21NaaGaaT1212B.1.360.001751
ORF3a21K21NaaGaaT1212R.10.00108
ORF3a21K21NaaGaaT1111AY.260.000311
ORF3a21K21NaaGaaT1111AY.470.000342
ORF3a21K21NaaGaaT1111AY.9.10.000921
ORF3a21K21NaaGaaT1010AY.1000.00046
ORF3a21K21NaaGaaT1010AY.200.000389
ORF3a21K21NaaGaaT1010B.1.1.3180.003018
ORF3a21K21NaaGaaT1010B.1.1600.000312
ORF3a21K21NaaGaaT1010B.1.5960.000871
ORF3a21K21NaaGaaT88B.1.1.2220.001632
ORF3a21K21NaaGaaT88B.1.177.190.011445
ORF3a21K21NaaGaaT88B.1.36.10.009122
ORF3a21K21NaaGaaT88B.1.4700.011236
ORF3a21K21NaaGaaC58B.1.5250.000566
ORF3a21K21NaaGaaT38B.1.5250.000339
ORF3a21K21NaaGaaT77AY.10.00277
ORF3a21K21NaaGaaT57AY.330.000334
ORF3a21K21NaaGaaC27AY.330.000134
ORF3a21K21NaaGaaT77AY.340.000679
ORF3a21K21NaaGaaC77AY.46.20.004447
ORF3a21K21NaaGaaT77B.1.1.2160.006233
ORF3a21K21NaaGaaT66AY.4.20.00013
ORF3a21K21NaaGaaT66AY.610.000629
ORF3a21K21NaaGaaT46AY.980.000316
ORF3a21K21NaaGaaC26AY.980.000158
ORF3a21K21NaaGaaT66AY.98.10.000291
ORF3a21K21NaaGaaT66B.1.1.280.001867
ORF3a21K21NaaGaaT66B.1.1.2980.005172
ORF3a21K21NaaGaaT66B.1.5240.008439
ORF3a21K21NaaGaaT66B.400.002186
ORF3a21K21NaaGaaT66P.1.150.001394
ORF3a21K21NaaGaaT55AY.1210.000677
ORF3a21K21NaaGaaT35AY.230.000209
ORF3a21K21NaaGaaC25AY.230.000139
ORF3a21K21NaaGaaT55AY.540.000477
ORF3a21K21NaaGaaT55AY.90.000338
ORF3a21K21NaaGaaT55B.1.1.3110.001791
ORF3a21K21NaaGaaT55B.1.1110.005875
ORF3a21K21NaaGaaT55B.1.2340.00066
ORF3a21K21NaaGaaT55B.1.3690.001426
ORF3a21K21NaaGaaT44AY.1180.000251
ORF3a21K21NaaGaaT44AY.420.000161
ORF3a21K21NaaGaaC24AY.460.000208
ORF3a21K21NaaGaaT24AY.460.000208
ORF3a21K21NaaGaaT44AY.510.003636
ORF3a21K21NaaGaaT44AY.700.000834
ORF3a21K21NaaGaaT44AY.80.002424
ORF3a21K21NaaGaaT44AY.800.004515
ORF3a21K21NaaGaaT44AY.9.20.000147
ORF3a21K21NaaGaaC44AY.920.001149
ORF3a21K21NaaGaaT44AY.99.20.000369
ORF3a21K21NaaGaaT44B.1.1.1710.014706
ORF3a21K21NaaGaaT44B.1.1.2140.000222
ORF3a21K21NaaGaaT44B.1.1.2410.008282
ORF3a21K21NaaGaaT44B.1.1.700.001364
ORF3a21K21NaaGaaT44B.1.2430.000278
ORF3a21K21NaaGaaT44B.1.36.170.001976
ORF3a21K21NaaGaaT44B.1.36.290.002069
ORF3a21K21NaaGaaT44B.1.4680.022857
ORF3a21K21NaaGaaT44B.1.4710.010929
ORF3a21K21NaaGaaC44B.1.5760.003626
ORF3a21K21NaaGaaT44C.360.003643
ORF3a21K21NaaGaaT44P.1.10.001271
ORF3a21K21NaaGaaT33AE.80.001467
ORF3a21K21NaaGaaT33AY.100.00159
ORF3a21K21NaaGaaT33AY.1100.000338
ORF3a21K21NaaGaaT33AY.1130.000427
ORF3a21K21NaaGaaC23AY.1140.000462
ORF3a21K21NaaGaaT13AY.1140.000231
ORF3a21K21NaaGaaT33AY.160.001139
ORF3a21K21NaaGaaT33AY.270.000194
ORF3a21K21NaaGaaT33AY.29.10.000662
ORF3a21K21NaaGaaT33AY.3.10.000256
ORF3a21K21NaaGaaT33AY.46.50.000595
ORF3a21K21NaaGaaT33AY.5.40.00083
ORF3a21K21NaaGaaT33AY.580.002722
ORF3a21K21NaaGaaT33AY.7.10.000338
ORF3a21K21NaaGaaT33AY.840.001312
ORF3a21K21NaaGaaT33B0.000383
ORF3a21K21NaaGaaT33B.1.1.250.001706
ORF3a21K21NaaGaaT33B.1.1.3510.00838
ORF3a21K21NaaGaaT33B.1.1.500.002037
ORF3a21K21NaaGaaT33B.1.177.570.000843
ORF3a21K21NaaGaaT33B.1.177.860.00055
ORF3a21K21NaaGaaT33B.1.2410.002435
ORF3a21K21NaaGaaT33B.1.351.50.001799
ORF3a21K21NaaGaaT33B.1.3670.002377
ORF3a21K21NaaGaaT33B.1.4040.003906
ORF3a21K21NaaGaaT33B.1.466.20.001174
ORF3a21K21NaaGaaT33B.1.5880.00273
ORF3a21K21NaaGaaT33B.1.5950.000783
ORF3a21K21NaaGaaT33B.1.617.10.000387
ORF3a21K21NaaGaaT33B.1.6250.007059
ORF3a21K21NaaGaaT33B.1.6280.001057
ORF3a21K21NaaGaaT33B.1.6370.000219
ORF3a21K21NaaGaaT33D.20.000225
ORF3a21K21NaaGaaT33N.50.0053
ORF3a21K21NaaGaaT33Q.80.000495
ORF3a21K21NaaGaaT22A0.000774
ORF3a21K21NaaGaaT22A.20.001324
ORF3a21K21NaaGaaT22AY.1060.00067
ORF3a21K21NaaGaaT22AY.116.10.000623
ORF3a21K21NaaGaaC22AY.190.002281
ORF3a21K21NaaGaaT12AY.240.000431
ORF3a21K21NaaGaaC12AY.240.000431
ORF3a21K21NaaGaaC12AY.46.40.000165
ORF3a21K21NaaGaaT12AY.46.40.000165
ORF3a21K21NaaGaaT12AY.5.30.000337
ORF3a21K21NaaGaaC12AY.5.30.000337
ORF3a21K21NaaGaaT22AY.520.001629
ORF3a21K21NaaGaaT22AY.550.001835
ORF3a21K21NaaGaaT22AY.570.001312
ORF3a21K21NaaGaaT22AY.60.000082
ORF3a21K21NaaGaaT22AY.650.001066
ORF3a21K21NaaGaaT22AY.70.000392
ORF3a21K21NaaGaaT12AY.750.000056
ORF3a21K21NaaGaaC12AY.750.000056
ORF3a21K21NaaGaaT22B.1.1.10.000653
ORF3a21K21NaaGaaT22B.1.1.3170.000823
ORF3a21K21NaaGaaT22B.1.1.4090.005666
ORF3a21K21NaaGaaT22B.1.1.50.016667
ORF3a21K21NaaGaaT22B.1.177.600.000437
ORF3a21K21NaaGaaT22B.1.177.730.001133
ORF3a21K21NaaGaaT22B.1.2100.004264
ORF3a21K21NaaGaaT22B.1.2790.001027
ORF3a21K21NaaGaaT22B.1.351.20.000605
ORF3a21K21NaaGaaT22B.1.36.180.00084
ORF3a21K21NaaGaaT22B.1.3660.009756
ORF3a21K21NaaGaaT22B.1.3980.005952
ORF3a21K21NaaGaaT22B.1.4030.006536
ORF3a21K21NaaGaaT22B.1.4380.013072
ORF3a21K21NaaGaaT22B.1.4690.00722
ORF3a21K21NaaGaaT22B.1.5640.000852
ORF3a21K21NaaGaaT22B.1.5680.002222
ORF3a21K21NaaGaaC22B.1.6200.001892
ORF3a21K21NaaGaaT22B.1.6320.013423
ORF3a21K21NaaGaaT22B.290.007018
ORF3a21K21NaaGaaT22P.1.10.10.01626
ORF3a21K21NaaGaaT22P.1.120.000968
ORF3a21K21NaaGaaT11A.10.000282
ORF3a21K21NaaGaaT11A.2.20.001689
ORF3a21K21NaaGaaT11A.2.50.000499
ORF3a21K21NaaGaaT11A.270.001656
ORF3a21K21NaaGaaC11AY.1050.000643
ORF3a21K21NaaGaaT11AY.1090.00074
ORF3a21K21NaaGaaT11AY.16.10.00047
ORF3a21K21NaaGaaT11AY.170.008197
ORF3a21K21NaaGaaT11AY.280.00189
ORF3a21K21NaaGaaT11AY.300.000396
ORF3a21K21NaaGaaT11AY.34.10.00051
ORF3a21K21NaaGaaT11AY.350.000233
ORF3a21K21NaaGaaT11AY.360.000148
ORF3a21K21NaaGaaT11AY.370.000316
ORF3a21K21NaaGaaT11AY.380.000499
ORF3a21K21NaaGaaT11AY.4.2.10.000149
ORF3a21K21NaaGaaT11AY.400.000964
ORF3a21K21NaaGaaT11AY.46.60.000072
ORF3a21K21NaaGaaT11AY.500.000799
ORF3a21K21NaaGaaT11AY.530.000288
ORF3a21K21NaaGaaT11AY.560.001605
ORF3a21K21NaaGaaT11AY.600.000938
ORF3a21K21NaaGaaC11AY.670.000464
ORF3a21K21NaaGaaT11AY.680.000274
ORF3a21K21NaaGaaT11AY.710.000475
ORF3a21K21NaaGaaT11AY.75.10.00018
ORF3a21K21NaaGaaT11AY.870.000833
ORF3a21K21NaaGaaC11AY.890.004902
ORF3a21K21NaaGaaT11AY.910.00073
ORF3a21K21NaaGaaC11AY.930.000273
ORF3a21K21NaaGaaT11B.1.1.2100.005714
ORF3a21K21NaaGaaT11B.1.1.2650.003155
ORF3a21K21NaaGaaT11B.1.1.2690.001353
ORF3a21K21NaaGaaT11B.1.1.2890.002083
ORF3a21K21NaaGaaT11B.1.1.2940.001266
ORF3a21K21NaaGaaT11B.1.1.3060.000438
ORF3a21K21NaaGaaT11B.1.1.330.000421
ORF3a21K21NaaGaaT11B.1.1.3470.018182
ORF3a21K21NaaGaaT11B.1.1.370.000193
ORF3a21K21NaaGaaT11B.1.1.4120.007634
ORF3a21K21NaaGaaT11B.1.1.4340.000349
ORF3a21K21NaaGaaT11B.1.1.4480.002033
ORF3a21K21NaaGaaT11B.1.1.5150.02
ORF3a21K21NaaGaaT11B.1.1.5210.005348
ORF3a21K21NaaGaaT11B.1.1.5230.001563
ORF3a21K21NaaGaaT11B.1.1.5240.020833
ORF3a21K21NaaGaaT11B.1.1.5260.003546
ORF3a21K21NaaGaaT11B.1.1.930.025641
ORF3a21K21NaaGaaT11B.1.1280.000635
ORF3a21K21NaaGaaT11B.1.1390.000733
ORF3a21K21NaaGaaT11B.1.160.310.008065
ORF3a21K21NaaGaaC11B.1.177.150.000631
ORF3a21K21NaaGaaT11B.1.177.170.000821
ORF3a21K21NaaGaaT11B.1.177.200.001517
ORF3a21K21NaaGaaT11B.1.177.230.003236
ORF3a21K21NaaGaaT11B.1.177.410.0025
ORF3a21K21NaaGaaT11B.1.177.830.001481
ORF3a21K21NaaGaaT11B.1.1790.003759
ORF3a21K21NaaGaaT11B.1.258.30.001675
ORF3a21K21NaaGaaT11B.1.2600.003344
ORF3a21K21NaaGaaT11B.1.2980.002114
ORF3a21K21NaaGaaT11B.1.3010.005917
ORF3a21K21NaaGaaT11B.1.3110.000275
ORF3a21K21NaaGaaT11B.1.3200.001245
ORF3a21K21NaaGaaT11B.1.351.30.000876
ORF3a21K21NaaGaaT11B.1.36.80.001
ORF3a21K21NaaGaaT11B.1.3620.001541
ORF3a21K21NaaGaaT11B.1.3990.001934
ORF3a21K21NaaGaaT11B.1.4110.003704
ORF3a21K21NaaGaaT11B.1.4220.000812
ORF3a21K21NaaGaaT11B.1.438.10.000107
ORF3a21K21NaaGaaT11B.1.4560.003268
ORF3a21K21NaaGaaT11B.1.4800.002488
ORF3a21K21NaaGaaT11B.1.4980.020408
ORF3a21K21NaaGaaT11B.1.5050.004386
ORF3a21K21NaaGaaT11B.1.5170.000427
ORF3a21K21NaaGaaT11B.1.5440.006024
ORF3a21K21NaaGaaT11B.1.5490.007194
ORF3a21K21NaaGaaT11B.1.5510.00129
ORF3a21K21NaaGaaT11B.1.5600.00463
ORF3a21K21NaaGaaT11B.1.575.10.002439
ORF3a21K21NaaGaaT11B.1.5820.000491
ORF3a21K21NaaGaaT11B.1.5900.004545
ORF3a21K21NaaGaaT11B.1.5990.00365
ORF3a21K21NaaGaaT11B.1.6190.000871
ORF3a21K21NaaGaaT11B.1.6340.003425
ORF3a21K21NaaGaaT11B.1.80.001972
ORF3a21K21NaaGaaT11B.30.000831
ORF3a21K21NaaGaaC11B.390.002331
ORF3a21K21NaaGaaT11B.520.010101
ORF3a21K21NaaGaaT11B.60.00091
ORF3a21K21NaaGaaT11C.160.00106
ORF3a21K21NaaGaaT11C.180.002591
ORF3a21K21NaaGaaC11C.300.001727
ORF3a21K21NaaGaaT11C.36.30.000567
ORF3a21K21NaaGaaT11P.1.130.000898
ORF3a21K21NaaGaaC11P.1.170.000162
ORF3a21K21NaaGaaT11P.1.20.001156
ORF3a21K21NaaGaaT11P.1.70.000319
ORF3a21K21NaaGaaT11P.20.000187
ORF3a21K21NaaGaaT11Q.10.000126
ORF3a21K21NaaGaaT11Q.30.000145

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.