CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF3a : Mut = H78Y

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF3a78H78YnonsynCacTac15416153820.99779525624-25626
ORF3a78H78YnonsynCaCTaT15416340.002205525624-25626

Details of the mutation H78Y within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF3a78H78YCacTac1538215416All0.002942
ORF3a78H78YCaCTaT3415416All0.000007
ORF3a78H78YCacTac33273340B.1.1.70.002978
ORF3a78H78YCaCTaT133340B.1.1.70.000012
ORF3a78H78YCacTac17841784AY.430.007904
ORF3a78H78YCacTac12171217AY.40.001894
ORF3a78H78YCacTac798798B.1.2580.053104
ORF3a78H78YCacTac614615B.1.1.4860.968454
ORF3a78H78YCaCTaT1615B.1.1.4860.001577
ORF3a78H78YCacTac550550AY.1030.003415
ORF3a78H78YCacTac404404B.1.617.20.001521
ORF3a78H78YCacTac388388B.1.1770.005109
ORF3a78H78YCacTac323331B.1.20.002844
ORF3a78H78YCaCTaT8331B.1.20.00007
ORF3a78H78YCacTac303303AY.560.486356
ORF3a78H78YCacTac277277B.1.2210.019676
ORF3a78H78YCacTac273273AY.950.207763
ORF3a78H78YCacTac234234AY.1200.0087
ORF3a78H78YCacTac207213B.10.001896
ORF3a78H78YCaCTaT6213B.10.000055
ORF3a78H78YCacTac206206B.1.2430.014334
ORF3a78H78YCacTac176176AY.30.001751
ORF3a78H78YCacTac156156AY.440.00095
ORF3a78H78YCacTac151151AY.260.004275
ORF3a78H78YCacTac150150C.2.11
ORF3a78H78YCacTac146146P.10.0023
ORF3a78H78YCacTac138138AY.250.00083
ORF3a78H78YCacTac133133AY.1160.038142
ORF3a78H78YCacTac118118B.1.1.280.036726
ORF3a78H78YCacTac109109B.1.10.001977
ORF3a78H78YCacTac106106AY.1020.00281
ORF3a78H78YCacTac103103B.1.3510.003062
ORF3a78H78YCacTac97100AY.470.003017
ORF3a78H78YCaCTaT3100AY.470.000093
ORF3a78H78YCacTac9595B.1.4290.002235
ORF3a78H78YCacTac8888AY.140.007745
ORF3a78H78YCacTac8181AY.4.20.001757
ORF3a78H78YCacTac6565AY.290.001025
ORF3a78H78YCacTac6060B.1.258.140.058824
ORF3a78H78YCacTac6060P.1.130.053908
ORF3a78H78YCacTac5757AY.1210.007713
ORF3a78H78YCacTac5757B.1.438.10.006114
ORF3a78H78YCacTac5555AY.360.008152
ORF3a78H78YCacTac5555AY.9.20.00202
ORF3a78H78YCacTac5353AY.980.004187
ORF3a78H78YCacTac5252AY.98.10.002518
ORF3a78H78YCacTac5151Q.30.007397
ORF3a78H78YCacTac4848AY.50.000991
ORF3a78H78YCacTac4848B.1.5250.005432
ORF3a78H78YCacTac4747A.23.10.033099
ORF3a78H78YCacTac4747C.370.005455
ORF3a78H78YCacTac4545B.1.1.2220.00918
ORF3a78H78YCacTac4545B.1.4270.002272
ORF3a78H78YCacTac4343AY.390.001063
ORF3a78H78YCacTac4343B.1.1.3680.132716
ORF3a78H78YCacTac4343Q.40.019554
ORF3a78H78YCacTac3838B.1.177.170.031199
ORF3a78H78YCacTac3636B.1.1.10.011761
ORF3a78H78YCacTac3636C.20.580645
ORF3a78H78YCacTac3535AY.200.00136
ORF3a78H78YCacTac3131AY.130.00499
ORF3a78H78YCacTac3131B.1.1.3110.011103
ORF3a78H78YCacTac2828AY.700.005838
ORF3a78H78YCacTac2727AK.10.341772
ORF3a78H78YCacTac2727AY.1180.001692
ORF3a78H78YCacTac2727B.1.1.5190.001072
ORF3a78H78YCacTac2626C.360.023679
ORF3a78H78YCacTac2424AY.230.001674
ORF3a78H78YCacTac2424B.1.220.031621
ORF3a78H78YCacTac2424R.10.00216
ORF3a78H78YCacTac2323B.1.1.3451
ORF3a78H78YCacTac2222AY.4.30.018519
ORF3a78H78YCacTac2222C.80.098214
ORF3a78H78YCacTac2121AY.540.002002
ORF3a78H78YCacTac2121AY.840.009186
ORF3a78H78YCacTac2121B.1.6210.001859
ORF3a78H78YCacTac2020AY.460.002082
ORF3a78H78YCacTac2020B.1.1.1070.645161
ORF3a78H78YCacTac2020B.1.1.3150.169492
ORF3a78H78YCacTac2020B.1.1600.000624
ORF3a78H78YCacTac1919Q.10.0024
ORF3a78H78YCacTac1818AY.960.037344
ORF3a78H78YCacTac1717AY.1190.0006
ORF3a78H78YCacTac1717AY.300.006727
ORF3a78H78YCacTac1717AY.610.001781
ORF3a78H78YCacTac1717B.1.617.10.002192
ORF3a78H78YCacTac1616AY.920.004596
ORF3a78H78YCacTac1616B.1.258.170.001664
ORF3a78H78YCacTac1616D.20.001201
ORF3a78H78YCacTac1616P.1.140.000765
ORF3a78H78YCacTac1515AY.70.00294
ORF3a78H78YCacTac1515B.1.1.2070.01773
ORF3a78H78YCacTac1515B.1.6230.008047
ORF3a78H78YCacTac1313AY.1100.001465
ORF3a78H78YCacTac1313AY.330.000868
ORF3a78H78YCacTac1212AY.1000.000552
ORF3a78H78YCacTac1212AY.750.000672
ORF3a78H78YCacTac1212B.1.1.150.162162
ORF3a78H78YCacTac1212B.1.1.2840.001289
ORF3a78H78YCacTac1212B.1.1.500.008147
ORF3a78H78YCacTac1212B.1.177.210.000918
ORF3a78H78YCacTac1212B.1.177.600.002621
ORF3a78H78YCacTac1212B.1.2060.009788
ORF3a78H78YCacTac1212B.1.5750.003641
ORF3a78H78YCacTac1111AY.120.10.003531
ORF3a78H78YCacTac1111AY.4.10.008112
ORF3a78H78YCacTac1111B.1.1.2040.033435
ORF3a78H78YCacTac1111P.1.150.002556
ORF3a78H78YCacTac1010AY.46.60.000722
ORF3a78H78YCacTac1010AY.90.000676
ORF3a78H78YCacTac1010B.1.1.1390.227273
ORF3a78H78YCacTac1010B.1.1.2160.008905
ORF3a78H78YCacTac1010B.1.3110.002746
ORF3a78H78YCacTac1010B.1.360.001459
ORF3a78H78YCacTac1010Q.80.001649
ORF3a78H78YCacTac99AY.790.010896
ORF3a78H78YCacTac99B.1.2220.015228
ORF3a78H78YCacTac99B.1.5910.095745
ORF3a78H78YCacTac88B.1.1.630.003086
ORF3a78H78YCacTac88B.1.2340.001056
ORF3a78H78YCacTac88B.1.36.290.004139
ORF3a78H78YCacTac88P.20.001493
ORF3a78H78YCacTac77AY.120.002212
ORF3a78H78YCacTac77AY.39.10.000277
ORF3a78H78YCacTac77AY.60.000288
ORF3a78H78YCacTac77B.1.1.3030.019337
ORF3a78H78YCacTac77B.1.5950.001827
ORF3a78H78YCacTac77B.1.5960.00061
ORF3a78H78YCacTac66AY.1170.000507
ORF3a78H78YCacTac66AY.420.000241
ORF3a78H78YCacTac66AY.450.00073
ORF3a78H78YCacTac66AY.9.10.000502
ORF3a78H78YCacTac66AY.970.010204
ORF3a78H78YCacTac55AY.1090.003698
ORF3a78H78YCacTac55AY.340.000485
ORF3a78H78YCacTac55AY.380.002496
ORF3a78H78YCacTac55AY.46.10.005133
ORF3a78H78YCacTac55AY.46.40.000823
ORF3a78H78YCacTac55AY.590.002648
ORF3a78H78YCacTac55B0.000639
ORF3a78H78YCacTac55B.1.1.1920.011547
ORF3a78H78YCacTac55B.1.1.3180.001509
ORF3a78H78YCacTac55B.1.1.4320.006329
ORF3a78H78YCacTac55B.1.160.130.138889
ORF3a78H78YCacTac55B.1.177.550.011655
ORF3a78H78YCacTac55B.1.3960.003529
ORF3a78H78YCacTac55B.1.466.20.001956
ORF3a78H78YCacTac55B.1.6280.001762
ORF3a78H78YCacTac55B.1.6370.000365
ORF3a78H78YCacTac55B.1.840.104167
ORF3a78H78YCacTac44A.2.50.001996
ORF3a78H78YCacTac44AY.16.10.00188
ORF3a78H78YCacTac44AY.350.000932
ORF3a78H78YCacTac44AY.46.30.003735
ORF3a78H78YCacTac44AY.75.10.000721
ORF3a78H78YCacTac44AY.930.001092
ORF3a78H78YCacTac44AZ.20.003284
ORF3a78H78YCacTac44B.1.1.2140.000222
ORF3a78H78YCacTac44B.1.1.250.002274
ORF3a78H78YCacTac44B.1.1.3060.001754
ORF3a78H78YCacTac44B.1.177.70.000659
ORF3a78H78YCacTac44C.330.235294
ORF3a78H78YCacTac33AE.80.001467
ORF3a78H78YCacTac33AY.1060.001005
ORF3a78H78YCacTac33AY.1110.000549
ORF3a78H78YCacTac33AY.1130.000427
ORF3a78H78YCacTac33AY.210.005693
ORF3a78H78YCacTac33AY.320.001597
ORF3a78H78YCacTac33AY.4.2.10.000447
ORF3a78H78YCacTac33AY.620.001307
ORF3a78H78YCacTac33AY.670.001393
ORF3a78H78YCacTac33AY.680.000821
ORF3a78H78YCacTac33AY.99.20.000276
ORF3a78H78YCacTac33B.1.1.2800.009259
ORF3a78H78YCacTac33B.1.1.3160.002775
ORF3a78H78YCacTac33B.1.1.3690.001339
ORF3a78H78YCacTac33B.1.1.4640.004418
ORF3a78H78YCacTac33B.1.1110.003525
ORF3a78H78YCacTac33B.1.177.100.002634
ORF3a78H78YCacTac33B.1.2320.001612
ORF3a78H78YCacTac33B.1.2400.000647
ORF3a78H78YCacTac33B.1.258.20.013514
ORF3a78H78YCacTac33B.1.3610.003866
ORF3a78H78YCacTac33B.1.3690.000856
ORF3a78H78YCacTac33B.1.3890.003006
ORF3a78H78YCacTac33B.1.4090.002344
ORF3a78H78YCacTac33B.1.6090.001438
ORF3a78H78YCacTac33C.160.003181
ORF3a78H78YCacTac33C.260.022059
ORF3a78H78YCacTac33C.36.30.001702
ORF3a78H78YCacTac22A.20.001324
ORF3a78H78YCacTac22AD.20.000438
ORF3a78H78YCacTac22AU.10.002532
ORF3a78H78YCacTac22AY.1050.001286
ORF3a78H78YCacTac22AY.1070.000932
ORF3a78H78YCacTac22AY.1080.002205
ORF3a78H78YCacTac22AY.120.20.002571
ORF3a78H78YCacTac22AY.160.000759
ORF3a78H78YCacTac22AY.23.10.000835
ORF3a78H78YCacTac22AY.3.10.000171
ORF3a78H78YCacTac22AY.370.000632
ORF3a78H78YCacTac22AY.410.000588
ORF3a78H78YCacTac22AY.480.00093
ORF3a78H78YCacTac22AY.5.30.000675
ORF3a78H78YCacTac22AY.570.001312
ORF3a78H78YCacTac22AY.850.000854
ORF3a78H78YCacTac22B.1.1.100.00223
ORF3a78H78YCacTac22B.1.1.1980.002937
ORF3a78H78YCacTac22B.1.1.2290.011494
ORF3a78H78YCacTac22B.1.1.2310.006192
ORF3a78H78YCacTac22B.1.1.2580.006515
ORF3a78H78YCacTac22B.1.1.2630.003115
ORF3a78H78YCacTac22B.1.1.2940.002532
ORF3a78H78YCacTac22B.1.1.330.000842
ORF3a78H78YCacTac22B.1.1.3480.001592
ORF3a78H78YCacTac22B.1.1.370.000386
ORF3a78H78YCacTac22B.1.1.3750.02381
ORF3a78H78YCacTac22B.1.1.3910.017094
ORF3a78H78YCacTac22B.1.1.4070.083333
ORF3a78H78YCacTac22B.1.1.4340.000697
ORF3a78H78YCacTac22B.1.1.530.027397
ORF3a78H78YCacTac22B.1.177.440.001038
ORF3a78H78YCacTac22B.1.177.730.001133
ORF3a78H78YCacTac22B.1.177.820.000955
ORF3a78H78YCacTac22B.1.177.860.000367
ORF3a78H78YCacTac22B.1.258.110.000793
ORF3a78H78YCacTac22B.1.258.30.00335
ORF3a78H78YCacTac22B.1.258.70.003824
ORF3a78H78YCacTac22B.1.36.160.002849
ORF3a78H78YCacTac22B.1.36.220.002415
ORF3a78H78YCacTac22B.1.36.380.003284
ORF3a78H78YCacTac22B.1.3990.003868
ORF3a78H78YCacTac22B.1.4970.00063
ORF3a78H78YCacTac22B.1.4990.002101
ORF3a78H78YCacTac22B.1.5260.000047
ORF3a78H78YCacTac22B.1.5560.015038
ORF3a78H78YCacTac22B.1.5650.001621
ORF3a78H78YCacTac22B.1.5770.001375
ORF3a78H78YCacTac22B.1.6270.00404
ORF3a78H78YCacTac22B.1.930.001867
ORF3a78H78YCacTac22C.350.001548
ORF3a78H78YCacTac22C.380.016129
ORF3a78H78YCaCTaT22Q.20.001227
ORF3a78H78YCacTac11A0.000387
ORF3a78H78YCacTac11AA.40.009091
ORF3a78H78YCacTac11AM.40.003571
ORF3a78H78YCacTac11AY.100.00053
ORF3a78H78YCacTac11AY.1040.001984
ORF3a78H78YCacTac11AY.110.001339
ORF3a78H78YCacTac11AY.1140.000231
ORF3a78H78YCacTac11AY.20.000356
ORF3a78H78YCacTac11AY.270.000065
ORF3a78H78YCacTac11AY.4.40.000409
ORF3a78H78YCacTac11AY.4.50.000107
ORF3a78H78YCacTac11AY.46.20.000635
ORF3a78H78YCacTac11AY.5.40.000277
ORF3a78H78YCacTac11AY.530.000288
ORF3a78H78YCacTac11AY.550.000917
ORF3a78H78YCacTac11AY.7.10.000113
ORF3a78H78YCacTac11AY.710.000475
ORF3a78H78YCacTac11AY.740.000116
ORF3a78H78YCacTac11AY.760.004831
ORF3a78H78YCacTac11AY.80.000606
ORF3a78H78YCacTac11AY.810.001992
ORF3a78H78YCacTac11AY.870.000833
ORF3a78H78YCacTac11AY.990.001049
ORF3a78H78YCacTac11B.1.1.1010.01
ORF3a78H78YCacTac11B.1.1.120.007463
ORF3a78H78YCacTac11B.1.1.1410.002012
ORF3a78H78YCacTac11B.1.1.1570.000913
ORF3a78H78YCacTac11B.1.1.1610.003534
ORF3a78H78YCacTac11B.1.1.2000.007463
ORF3a78H78YCacTac11B.1.1.2200.001859
ORF3a78H78YCaCTaT11B.1.1.2210.010101
ORF3a78H78YCacTac11B.1.1.2690.001353
ORF3a78H78YCacTac11B.1.1.2750.011236
ORF3a78H78YCacTac11B.1.1.2790.001121
ORF3a78H78YCacTac11B.1.1.2900.018182
ORF3a78H78YCacTac11B.1.1.3010.001179
ORF3a78H78YCacTac11B.1.1.3120.001912
ORF3a78H78YCacTac11B.1.1.3170.000412
ORF3a78H78YCacTac11B.1.1.3220.008772
ORF3a78H78YCacTac11B.1.1.3350.012987
ORF3a78H78YCacTac11B.1.1.3710.010417
ORF3a78H78YCacTac11B.1.1.3720.000689
ORF3a78H78YCacTac11B.1.1.3970.002252
ORF3a78H78YCacTac11B.1.1.3980.003226
ORF3a78H78YCacTac11B.1.1.4060.006494
ORF3a78H78YCacTac11B.1.1.4120.007634
ORF3a78H78YCacTac11B.1.1.4330.001425
ORF3a78H78YCacTac11B.1.1.4480.002033
ORF3a78H78YCacTac11B.1.1.4490.022727
ORF3a78H78YCacTac11B.1.1.470.005348
ORF3a78H78YCacTac11B.1.1.5260.003546
ORF3a78H78YCacTac11B.1.1.590.006494
ORF3a78H78YCacTac11B.1.1.700.000341
ORF3a78H78YCacTac11B.1.1.890.006061
ORF3a78H78YCacTac11B.1.1260.001276
ORF3a78H78YCacTac11B.1.130.002375
ORF3a78H78YCacTac11B.1.160.220.006757
ORF3a78H78YCacTac11B.1.177.120.000152
ORF3a78H78YCacTac11B.1.177.150.000631
ORF3a78H78YCacTac11B.1.177.180.00116
ORF3a78H78YCacTac11B.1.177.320.00135
ORF3a78H78YCacTac11B.1.177.40.000211
ORF3a78H78YCacTac11B.1.177.520.001757
ORF3a78H78YCacTac11B.1.177.570.000281
ORF3a78H78YCacTac11B.1.177.580.001332
ORF3a78H78YCacTac11B.1.177.60.000977
ORF3a78H78YCacTac11B.1.177.750.001041
ORF3a78H78YCacTac11B.1.177.770.000726
ORF3a78H78YCacTac11B.1.177.80.000752
ORF3a78H78YCacTac11B.1.177.850.005435
ORF3a78H78YCacTac11B.1.1950.005025
ORF3a78H78YCacTac11B.1.2100.002132
ORF3a78H78YCacTac11B.1.2350.002519
ORF3a78H78YCacTac11B.1.258.100.011364
ORF3a78H78YCacTac11B.1.258.120.007874
ORF3a78H78YCacTac11B.1.258.220.002667
ORF3a78H78YCacTac11B.1.2700.005618
ORF3a78H78YCacTac11B.1.30.002618
ORF3a78H78YCacTac11B.1.3130.006579
ORF3a78H78YCacTac11B.1.3240.001605
ORF3a78H78YCacTac11B.1.3560.001727
ORF3a78H78YCacTac11B.1.36.10.00114
ORF3a78H78YCacTac11B.1.36.350.002604
ORF3a78H78YCacTac11B.1.36.80.001
ORF3a78H78YCacTac11B.1.3670.000792
ORF3a78H78YCacTac11B.1.3800.006623
ORF3a78H78YCacTac11B.1.3910.001127
ORF3a78H78YCacTac11B.1.4040.001302
ORF3a78H78YCacTac11B.1.4210.007463
ORF3a78H78YCacTac11B.1.4320.011236
ORF3a78H78YCacTac11B.1.4430.004673
ORF3a78H78YCacTac11B.1.5170.000427
ORF3a78H78YCacTac11B.1.5240.001406
ORF3a78H78YCacTac11B.1.5270.003704
ORF3a78H78YCacTac11B.1.5390.017544
ORF3a78H78YCacTac11B.1.5580.004566
ORF3a78H78YCacTac11B.1.5610.000397
ORF3a78H78YCacTac11B.1.5700.002941
ORF3a78H78YCacTac11B.1.5930.01087
ORF3a78H78YCacTac11B.1.6060.006024
ORF3a78H78YCacTac11B.1.617.30.002985
ORF3a78H78YCacTac11B.1.6340.003425
ORF3a78H78YCacTac11B.1.6360.006711
ORF3a78H78YCacTac11B.1.780.008547
ORF3a78H78YCacTac11B.1.80.001972
ORF3a78H78YCacTac11B.1.90.006173
ORF3a78H78YCacTac11B.1.960.018868
ORF3a78H78YCacTac11B.520.010101
ORF3a78H78YCacTac11C.140.004329
ORF3a78H78YCacTac11C.170.055556
ORF3a78H78YCacTac11C.300.001727
ORF3a78H78YCacTac11C.340.037037
ORF3a78H78YCacTac11C.390.018868
ORF3a78H78YCacTac11C.50.090909
ORF3a78H78YCacTac11L.30.003546
ORF3a78H78YCacTac11N.50.001767
ORF3a78H78YCacTac11P.1.120.000484
ORF3a78H78YCacTac11P.1.160.000374
ORF3a78H78YCacTac11P.1.170.000162

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.