CoV-GLUE | Mutations | Mutation
Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):
ORF | CodonNum | Mut | ORF1abMut | MutType | RefCodon | MutCodon | AACount | CodonCount | CodonProp | Genome Position |
ORF3a | 182 | H182Y | nonsyn | Cat | Tat | 5713 | 5712 | 0.999825 | 25936-25938 | |
ORF3a | 182 | H182Y | nonsyn | CaT | TaC | 5713 | 1 | 0.000175039 | 25936-25938 |
Details of the mutation H182Y within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):
ORF | CodonNum | Mut | RefCodon | MutCodon | CodonCount | AACount | Lineage | LineageCodonProp |
ORF3a | 182 | H182Y | Cat | Tat | 5712 | 5713 | All | 0.001092 |
ORF3a | 182 | H182Y | CaT | TaC | 1 | 5713 | All | 0 |
ORF3a | 182 | H182Y | Cat | Tat | 3201 | 3201 | B.1.1.7 | 0.002866 |
ORF3a | 182 | H182Y | Cat | Tat | 997 | 997 | B.1.1.298 | 0.859483 |
ORF3a | 182 | H182Y | Cat | Tat | 324 | 324 | AY.4 | 0.000504 |
ORF3a | 182 | H182Y | Cat | Tat | 89 | 89 | D.2 | 0.006679 |
ORF3a | 182 | H182Y | Cat | Tat | 81 | 81 | B.1.617.2 | 0.000305 |
ORF3a | 182 | H182Y | Cat | Tat | 61 | 61 | B.1.1 | 0.001107 |
ORF3a | 182 | H182Y | Cat | Tat | 57 | 57 | AY.43 | 0.000253 |
ORF3a | 182 | H182Y | Cat | Tat | 54 | 54 | AY.98 | 0.004266 |
ORF3a | 182 | H182Y | Cat | Tat | 49 | 49 | B.1 | 0.000449 |
ORF3a | 182 | H182Y | Cat | Tat | 47 | 47 | AY.25 | 0.000283 |
ORF3a | 182 | H182Y | Cat | Tat | 46 | 46 | B.1.36 | 0.006711 |
ORF3a | 182 | H182Y | Cat | Tat | 41 | 42 | AY.44 | 0.00025 |
ORF3a | 182 | H182Y | CaT | TaC | 1 | 42 | AY.44 | 0.000006 |
ORF3a | 182 | H182Y | Cat | Tat | 41 | 41 | AY.29 | 0.000647 |
ORF3a | 182 | H182Y | Cat | Tat | 39 | 39 | B.1.2 | 0.000343 |
ORF3a | 182 | H182Y | Cat | Tat | 33 | 33 | AY.46.6 | 0.002383 |
ORF3a | 182 | H182Y | Cat | Tat | 33 | 33 | B.1.8 | 0.065089 |
ORF3a | 182 | H182Y | Cat | Tat | 25 | 25 | B.1.177.65 | 0.016633 |
ORF3a | 182 | H182Y | Cat | Tat | 23 | 23 | P.1 | 0.000362 |
ORF3a | 182 | H182Y | Cat | Tat | 20 | 20 | AY.35 | 0.004661 |
ORF3a | 182 | H182Y | Cat | Tat | 20 | 20 | B.1.177 | 0.000263 |
ORF3a | 182 | H182Y | Cat | Tat | 19 | 19 | C.36.3 | 0.010777 |
ORF3a | 182 | H182Y | Cat | Tat | 17 | 17 | AY.103 | 0.000106 |
ORF3a | 182 | H182Y | Cat | Tat | 17 | 17 | AY.30 | 0.006727 |
ORF3a | 182 | H182Y | Cat | Tat | 17 | 17 | B.1.429 | 0.0004 |
ORF3a | 182 | H182Y | Cat | Tat | 16 | 16 | AW.1 | 0.04878 |
ORF3a | 182 | H182Y | Cat | Tat | 15 | 15 | B.1.36.18 | 0.006303 |
ORF3a | 182 | H182Y | Cat | Tat | 13 | 13 | B.1.258 | 0.000865 |
ORF3a | 182 | H182Y | Cat | Tat | 12 | 12 | B.1.177.73 | 0.006795 |
ORF3a | 182 | H182Y | Cat | Tat | 11 | 11 | AY.23 | 0.000767 |
ORF3a | 182 | H182Y | Cat | Tat | 11 | 11 | B.1.526 | 0.000259 |
ORF3a | 182 | H182Y | Cat | Tat | 10 | 10 | AY.102 | 0.000265 |
ORF3a | 182 | H182Y | Cat | Tat | 10 | 10 | AY.61 | 0.001048 |
ORF3a | 182 | H182Y | Cat | Tat | 8 | 8 | B.1.1.369 | 0.00357 |
ORF3a | 182 | H182Y | Cat | Tat | 7 | 7 | B.1.1.316 | 0.006475 |
ORF3a | 182 | H182Y | Cat | Tat | 7 | 7 | B.1.1.8 | 0.02509 |
ORF3a | 182 | H182Y | Cat | Tat | 7 | 7 | B.1.177.21 | 0.000535 |
ORF3a | 182 | H182Y | Cat | Tat | 7 | 7 | B.1.466.2 | 0.002739 |
ORF3a | 182 | H182Y | Cat | Tat | 7 | 7 | C.37 | 0.000812 |
ORF3a | 182 | H182Y | Cat | Tat | 6 | 6 | AY.75.1 | 0.001082 |
ORF3a | 182 | H182Y | Cat | Tat | 5 | 5 | AY.12 | 0.00158 |
ORF3a | 182 | H182Y | Cat | Tat | 5 | 5 | AY.47 | 0.000156 |
ORF3a | 182 | H182Y | Cat | Tat | 4 | 4 | AY.118 | 0.000251 |
ORF3a | 182 | H182Y | Cat | Tat | 4 | 4 | AY.37 | 0.001264 |
ORF3a | 182 | H182Y | Cat | Tat | 4 | 4 | AY.39 | 0.000099 |
ORF3a | 182 | H182Y | Cat | Tat | 4 | 4 | AZ.1 | 0.003469 |
ORF3a | 182 | H182Y | Cat | Tat | 4 | 4 | B.1.1.41 | 0.025316 |
ORF3a | 182 | H182Y | Cat | Tat | 4 | 4 | B.1.351 | 0.000119 |
ORF3a | 182 | H182Y | Cat | Tat | 4 | 4 | B.1.351.2 | 0.00121 |
ORF3a | 182 | H182Y | Cat | Tat | 4 | 4 | B.1.525 | 0.000453 |
ORF3a | 182 | H182Y | Cat | Tat | 4 | 4 | B.1.617.1 | 0.000516 |
ORF3a | 182 | H182Y | Cat | Tat | 4 | 4 | R.1 | 0.00036 |
ORF3a | 182 | H182Y | Cat | Tat | 3 | 3 | AY.13 | 0.000483 |
ORF3a | 182 | H182Y | Cat | Tat | 3 | 3 | AY.16 | 0.001139 |
ORF3a | 182 | H182Y | Cat | Tat | 3 | 3 | AY.20 | 0.000117 |
ORF3a | 182 | H182Y | Cat | Tat | 3 | 3 | AY.24 | 0.001293 |
ORF3a | 182 | H182Y | Cat | Tat | 3 | 3 | AY.26 | 0.000085 |
ORF3a | 182 | H182Y | Cat | Tat | 3 | 3 | AY.4.2 | 0.000065 |
ORF3a | 182 | H182Y | Cat | Tat | 3 | 3 | AY.60 | 0.002814 |
ORF3a | 182 | H182Y | Cat | Tat | 3 | 3 | AY.70 | 0.000626 |
ORF3a | 182 | H182Y | Cat | Tat | 3 | 3 | B.1.1.214 | 0.000166 |
ORF3a | 182 | H182Y | Cat | Tat | 3 | 3 | B.1.1.222 | 0.000612 |
ORF3a | 182 | H182Y | Cat | Tat | 3 | 3 | B.1.1.28 | 0.000934 |
ORF3a | 182 | H182Y | Cat | Tat | 3 | 3 | B.1.160 | 0.000094 |
ORF3a | 182 | H182Y | Cat | Tat | 3 | 3 | B.1.243 | 0.000209 |
ORF3a | 182 | H182Y | Cat | Tat | 3 | 3 | B.1.391 | 0.003382 |
ORF3a | 182 | H182Y | Cat | Tat | 3 | 3 | M.3 | 0.230769 |
ORF3a | 182 | H182Y | Cat | Tat | 2 | 2 | A | 0.000774 |
ORF3a | 182 | H182Y | Cat | Tat | 2 | 2 | AY.107 | 0.000932 |
ORF3a | 182 | H182Y | Cat | Tat | 2 | 2 | AY.113 | 0.000285 |
ORF3a | 182 | H182Y | Cat | Tat | 2 | 2 | AY.119 | 0.000071 |
ORF3a | 182 | H182Y | Cat | Tat | 2 | 2 | AY.120 | 0.000074 |
ORF3a | 182 | H182Y | Cat | Tat | 2 | 2 | AY.121 | 0.000271 |
ORF3a | 182 | H182Y | Cat | Tat | 2 | 2 | AY.29.1 | 0.000441 |
ORF3a | 182 | H182Y | Cat | Tat | 2 | 2 | AY.3 | 0.00002 |
ORF3a | 182 | H182Y | Cat | Tat | 2 | 2 | AY.54 | 0.000191 |
ORF3a | 182 | H182Y | Cat | Tat | 2 | 2 | AY.75 | 0.000112 |
ORF3a | 182 | H182Y | Cat | Tat | 2 | 2 | B.1.1.161 | 0.007067 |
ORF3a | 182 | H182Y | Cat | Tat | 2 | 2 | B.1.1.277 | 0.001517 |
ORF3a | 182 | H182Y | Cat | Tat | 2 | 2 | B.1.1.420 | 0.002012 |
ORF3a | 182 | H182Y | Cat | Tat | 2 | 2 | B.1.1.448 | 0.004065 |
ORF3a | 182 | H182Y | Cat | Tat | 2 | 2 | B.1.1.464 | 0.002946 |
ORF3a | 182 | H182Y | Cat | Tat | 2 | 2 | B.1.1.519 | 0.000079 |
ORF3a | 182 | H182Y | Cat | Tat | 2 | 2 | B.1.177.35 | 0.001382 |
ORF3a | 182 | H182Y | Cat | Tat | 2 | 2 | B.1.177.41 | 0.005 |
ORF3a | 182 | H182Y | Cat | Tat | 2 | 2 | B.1.221 | 0.000142 |
ORF3a | 182 | H182Y | Cat | Tat | 2 | 2 | B.1.575 | 0.000607 |
ORF3a | 182 | H182Y | Cat | Tat | 2 | 2 | B.1.596 | 0.000174 |
ORF3a | 182 | H182Y | Cat | Tat | 2 | 2 | B.1.609 | 0.000959 |
ORF3a | 182 | H182Y | Cat | Tat | 2 | 2 | B.1.628 | 0.000705 |
ORF3a | 182 | H182Y | Cat | Tat | 2 | 2 | P.1.14 | 0.000096 |
ORF3a | 182 | H182Y | Cat | Tat | 2 | 2 | Q.1 | 0.000253 |
ORF3a | 182 | H182Y | Cat | Tat | 1 | 1 | A.27 | 0.001656 |
ORF3a | 182 | H182Y | Cat | Tat | 1 | 1 | AY.14 | 0.000088 |
ORF3a | 182 | H182Y | Cat | Tat | 1 | 1 | AY.16.1 | 0.00047 |
ORF3a | 182 | H182Y | Cat | Tat | 1 | 1 | AY.3.1 | 0.000085 |
ORF3a | 182 | H182Y | Cat | Tat | 1 | 1 | AY.32 | 0.000532 |
ORF3a | 182 | H182Y | Cat | Tat | 1 | 1 | AY.36 | 0.000148 |
ORF3a | 182 | H182Y | Cat | Tat | 1 | 1 | AY.39.1 | 0.00004 |
ORF3a | 182 | H182Y | Cat | Tat | 1 | 1 | AY.4.2.1 | 0.000149 |
ORF3a | 182 | H182Y | Cat | Tat | 1 | 1 | AY.4.5 | 0.000107 |
ORF3a | 182 | H182Y | Cat | Tat | 1 | 1 | AY.42 | 0.00004 |
ORF3a | 182 | H182Y | Cat | Tat | 1 | 1 | AY.45 | 0.000122 |
ORF3a | 182 | H182Y | Cat | Tat | 1 | 1 | AY.46 | 0.000104 |
ORF3a | 182 | H182Y | Cat | Tat | 1 | 1 | AY.46.4 | 0.000165 |
ORF3a | 182 | H182Y | Cat | Tat | 1 | 1 | AY.48 | 0.000465 |
ORF3a | 182 | H182Y | Cat | Tat | 1 | 1 | AY.5 | 0.000021 |
ORF3a | 182 | H182Y | Cat | Tat | 1 | 1 | AY.52 | 0.000814 |
ORF3a | 182 | H182Y | Cat | Tat | 1 | 1 | AY.6 | 0.000041 |
ORF3a | 182 | H182Y | Cat | Tat | 1 | 1 | AY.65 | 0.000533 |
ORF3a | 182 | H182Y | Cat | Tat | 1 | 1 | AY.68 | 0.000274 |
ORF3a | 182 | H182Y | Cat | Tat | 1 | 1 | AY.69 | 0.000187 |
ORF3a | 182 | H182Y | Cat | Tat | 1 | 1 | AY.7.2 | 0.000559 |
ORF3a | 182 | H182Y | Cat | Tat | 1 | 1 | AY.8 | 0.000606 |
ORF3a | 182 | H182Y | Cat | Tat | 1 | 1 | AY.85 | 0.000427 |
ORF3a | 182 | H182Y | Cat | Tat | 1 | 1 | AY.99 | 0.001049 |
ORF3a | 182 | H182Y | Cat | Tat | 1 | 1 | AY.99.1 | 0.001553 |
ORF3a | 182 | H182Y | Cat | Tat | 1 | 1 | AY.99.2 | 0.000092 |
ORF3a | 182 | H182Y | Cat | Tat | 1 | 1 | B | 0.000128 |
ORF3a | 182 | H182Y | Cat | Tat | 1 | 1 | B.1.1.157 | 0.000913 |
ORF3a | 182 | H182Y | Cat | Tat | 1 | 1 | B.1.1.273 | 0.006757 |
ORF3a | 182 | H182Y | Cat | Tat | 1 | 1 | B.1.1.286 | 0.002899 |
ORF3a | 182 | H182Y | Cat | Tat | 1 | 1 | B.1.1.291 | 0.000742 |
ORF3a | 182 | H182Y | Cat | Tat | 1 | 1 | B.1.1.318 | 0.000302 |
ORF3a | 182 | H182Y | Cat | Tat | 1 | 1 | B.1.1.371 | 0.010417 |
ORF3a | 182 | H182Y | Cat | Tat | 1 | 1 | B.1.1.397 | 0.002252 |
ORF3a | 182 | H182Y | Cat | Tat | 1 | 1 | B.1.1.70 | 0.000341 |
ORF3a | 182 | H182Y | Cat | Tat | 1 | 1 | B.1.1.91 | 0.166667 |
ORF3a | 182 | H182Y | Cat | Tat | 1 | 1 | B.1.160.27 | 0.015152 |
ORF3a | 182 | H182Y | Cat | Tat | 1 | 1 | B.1.177.4 | 0.000211 |
ORF3a | 182 | H182Y | Cat | Tat | 1 | 1 | B.1.177.57 | 0.000281 |
ORF3a | 182 | H182Y | Cat | Tat | 1 | 1 | B.1.232 | 0.000537 |
ORF3a | 182 | H182Y | Cat | Tat | 1 | 1 | B.1.236 | 0.002053 |
ORF3a | 182 | H182Y | Cat | Tat | 1 | 1 | B.1.240 | 0.000216 |
ORF3a | 182 | H182Y | Cat | Tat | 1 | 1 | B.1.241 | 0.000812 |
ORF3a | 182 | H182Y | Cat | Tat | 1 | 1 | B.1.247 | 0.014925 |
ORF3a | 182 | H182Y | Cat | Tat | 1 | 1 | B.1.311 | 0.000275 |
ORF3a | 182 | H182Y | Cat | Tat | 1 | 1 | B.1.338 | 0.008621 |
ORF3a | 182 | H182Y | Cat | Tat | 1 | 1 | B.1.36.10 | 0.004785 |
ORF3a | 182 | H182Y | Cat | Tat | 1 | 1 | B.1.369 | 0.000285 |
ORF3a | 182 | H182Y | Cat | Tat | 1 | 1 | B.1.408 | 0.00369 |
ORF3a | 182 | H182Y | Cat | Tat | 1 | 1 | B.1.422 | 0.000812 |
ORF3a | 182 | H182Y | Cat | Tat | 1 | 1 | B.1.427 | 0.00005 |
ORF3a | 182 | H182Y | Cat | Tat | 1 | 1 | B.1.509 | 0.000866 |
ORF3a | 182 | H182Y | Cat | Tat | 1 | 1 | B.1.532 | 0.006211 |
ORF3a | 182 | H182Y | Cat | Tat | 1 | 1 | B.1.575.1 | 0.002439 |
ORF3a | 182 | H182Y | Cat | Tat | 1 | 1 | B.1.595 | 0.000261 |
ORF3a | 182 | H182Y | Cat | Tat | 1 | 1 | B.1.619 | 0.000871 |
ORF3a | 182 | H182Y | Cat | Tat | 1 | 1 | B.1.621 | 0.000089 |
ORF3a | 182 | H182Y | Cat | Tat | 1 | 1 | B.1.621.1 | 0.000506 |
ORF3a | 182 | H182Y | Cat | Tat | 1 | 1 | B.1.637 | 0.000073 |
ORF3a | 182 | H182Y | Cat | Tat | 1 | 1 | B.40 | 0.000364 |
ORF3a | 182 | H182Y | Cat | Tat | 1 | 1 | C.14 | 0.004329 |
ORF3a | 182 | H182Y | Cat | Tat | 1 | 1 | C.33 | 0.058824 |
ORF3a | 182 | H182Y | Cat | Tat | 1 | 1 | C.34 | 0.037037 |
ORF3a | 182 | H182Y | Cat | Tat | 1 | 1 | C.35 | 0.000774 |
ORF3a | 182 | H182Y | Cat | Tat | 1 | 1 | C.37.1 | 0.002618 |
ORF3a | 182 | H182Y | Cat | Tat | 1 | 1 | D.3 | 0.005917 |
ORF3a | 182 | H182Y | Cat | Tat | 1 | 1 | K.1 | 0.02381 |
ORF3a | 182 | H182Y | Cat | Tat | 1 | 1 | P.1.8 | 0.004785 |
ORF3a | 182 | H182Y | Cat | Tat | 1 | 1 | Z.1 | 0.00289 |
CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk
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