CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF3a : Mut = G49V

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF3a49G49VnonsyngGcgTc10626106220.99962425537-25539
ORF3a49G49VnonsyngGCgTT1062640.00037643525537-25539

Details of the mutation G49V within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF3a49G49VgGcgTc1062210626All0.002032
ORF3a49G49VgGCgTT410626All0.000001
ORF3a49G49VgGcgTc36453645B.1.617.20.013725
ORF3a49G49VgGcgTc12761277AY.1020.033832
ORF3a49G49VgGCgTT11277AY.1020.000027
ORF3a49G49VgGcgTc11521152AY.60.04738
ORF3a49G49VgGcgTc907907AY.40.001412
ORF3a49G49VgGcgTc489489B.1.1.70.000438
ORF3a49G49VgGcgTc345345AY.440.0021
ORF3a49G49VgGcgTc319319AY.430.001413
ORF3a49G49VgGcgTc238238AY.1030.001478
ORF3a49G49VgGcgTc200200AY.390.004942
ORF3a49G49VgGcgTc111111B.1.20.000977
ORF3a49G49VgGcgTc9797B.1.4290.002282
ORF3a49G49VgGcgTc8383AY.120.2.10.041355
ORF3a49G49VgGcgTc7878B.1.3510.002319
ORF3a49G49VgGcgTc7373AY.1200.002714
ORF3a49G49VgGcgTc6969AY.1170.005832
ORF3a49G49VgGcgTc6363AY.4.20.001366
ORF3a49G49VgGcgTc6060AY.34.10.030597
ORF3a49G49VgGcgTc5656AY.260.001585
ORF3a49G49VgGcgTc5656AY.330.00374
ORF3a49G49VgGcgTc5555AY.250.000331
ORF3a49G49VgGcgTc5555B.1.6200.052034
ORF3a49G49VgGcgTc5050AY.230.003487
ORF3a49G49VgGcgTc4545AY.460.004684
ORF3a49G49VgGcgTc3939AY.50.000805
ORF3a49G49VgGcgTc3737AY.450.004502
ORF3a49G49VgGcgTc3535AY.1130.004984
ORF3a49G49VgGcgTc3434B.1.10.000617
ORF3a49G49VgGcgTc3434B.1.1770.000448
ORF3a49G49VgGcgTc3333AY.920.00948
ORF3a49G49VgGcgTc2929B.10.000266
ORF3a49G49VgGcgTc2828AY.9.20.001028
ORF3a49G49VgGcgTc2626P.10.00041
ORF3a49G49VgGcgTc2424AY.30.000239
ORF3a49G49VgGcgTc2323AY.1160.006596
ORF3a49G49VgGcgTc2121AY.980.001659
ORF3a49G49VgGcgTc2020AY.1180.001253
ORF3a49G49VgGcgTc2020AY.840.008749
ORF3a49G49VgGcgTc1818AY.200.0007
ORF3a49G49VgGcgTc1717AY.120.10.005457
ORF3a49G49VgGcgTc1717AY.770.019166
ORF3a49G49VgGcgTc1616AY.1190.000565
ORF3a49G49VgGcgTc1616AY.540.001526
ORF3a49G49VgGcgTc1616P.1.150.003717
ORF3a49G49VgGcgTc1515AY.5.30.005061
ORF3a49G49VgGcgTc1515AY.730.00998
ORF3a49G49VgGcgTc1515B.1.2210.001065
ORF3a49G49VgGcgTc1414AY.750.000784
ORF3a49G49VgGcgTc1414AY.950.010654
ORF3a49G49VgGcgTc1414P.30.022329
ORF3a49G49VgGcgTc1313AY.1110.002381
ORF3a49G49VgGcgTc1313AY.420.000523
ORF3a49G49VgGcgTc1212B.1.1.5190.000477
ORF3a49G49VgGcgTc1111AY.360.00163
ORF3a49G49VgGcgTc1111AY.98.10.000533
ORF3a49G49VgGcgTc1111B.1.4270.000555
ORF3a49G49VgGcgTc1010AY.240.00431
ORF3a49G49VgGcgTc1010AY.5.40.002767
ORF3a49G49VgGcgTc1010B.1.1.2440.153846
ORF3a49G49VgGcgTc1010B.1.1600.000312
ORF3a49G49VgGcgTc99AY.1000.000414
ORF3a49G49VgGcgTc99B.1.1.2160.008014
ORF3a49G49VgGcgTc99P.1.10.002859
ORF3a49G49VgGcgTc88AY.160.003037
ORF3a49G49VgGcgTc88AY.3.10.000682
ORF3a49G49VgGcgTc88AY.4.50.00086
ORF3a49G49VgGcgTc88AY.550.007339
ORF3a49G49VgGcgTc58AY.75.10.000902
ORF3a49G49VgGCgTT38AY.75.10.000541
ORF3a49G49VgGcgTc88B.1.1.3180.002414
ORF3a49G49VgGcgTc77AY.1100.000789
ORF3a49G49VgGcgTc77AY.290.00011
ORF3a49G49VgGcgTc77AY.46.40.001152
ORF3a49G49VgGcgTc77AY.590.003708
ORF3a49G49VgGcgTc77AY.610.000733
ORF3a49G49VgGcgTc77B.1.2400.001509
ORF3a49G49VgGcgTc77Q.30.001015
ORF3a49G49VgGcgTc66AY.1210.000812
ORF3a49G49VgGcgTc66AY.470.000187
ORF3a49G49VgGcgTc66AY.890.029412
ORF3a49G49VgGcgTc66AY.910.004383
ORF3a49G49VgGcgTc66B.1.6280.002114
ORF3a49G49VgGcgTc55AY.320.002662
ORF3a49G49VgGcgTc55AY.530.001438
ORF3a49G49VgGcgTc55AY.580.004537
ORF3a49G49VgGcgTc55AY.680.001369
ORF3a49G49VgGcgTc55AY.990.005247
ORF3a49G49VgGcgTc55B.1.2340.00066
ORF3a49G49VgGcgTc55C.370.00058
ORF3a49G49VgGcgTc44AY.1140.000924
ORF3a49G49VgGcgTc44AY.46.20.002541
ORF3a49G49VgGcgTc44AY.700.000834
ORF3a49G49VgGcgTc44AY.740.000463
ORF3a49G49VgGcgTc44AY.780.006163
ORF3a49G49VgGcgTc44AY.810.007968
ORF3a49G49VgGcgTc44B.1.2430.000278
ORF3a49G49VgGcgTc44B.1.3110.001098
ORF3a49G49VgGcgTc44B.1.5250.000453
ORF3a49G49VgGcgTc44C.350.003096
ORF3a49G49VgGcgTc33A.10.000846
ORF3a49G49VgGcgTc33AY.1040.005952
ORF3a49G49VgGcgTc33AY.1050.001929
ORF3a49G49VgGcgTc33AY.1060.001005
ORF3a49G49VgGcgTc33AY.340.000291
ORF3a49G49VgGcgTc33AY.410.000882
ORF3a49G49VgGcgTc33AY.46.10.00308
ORF3a49G49VgGcgTc33AY.46.60.000217
ORF3a49G49VgGcgTc33AY.500.002398
ORF3a49G49VgGcgTc33AY.520.002443
ORF3a49G49VgGcgTc33AY.870.002498
ORF3a49G49VgGcgTc33AY.930.000819
ORF3a49G49VgGcgTc33B.1.1.2140.000166
ORF3a49G49VgGcgTc33B.1.1.3910.025641
ORF3a49G49VgGcgTc33B.1.177.180.00348
ORF3a49G49VgGcgTc33B.1.258.170.000312
ORF3a49G49VgGcgTc33B.1.3890.003006
ORF3a49G49VgGcgTc33B.1.617.10.000387
ORF3a49G49VgGcgTc33B.1.621.10.001517
ORF3a49G49VgGcgTc22A.23.10.001408
ORF3a49G49VgGcgTc22AY.10.000791
ORF3a49G49VgGcgTc22AY.1010.000981
ORF3a49G49VgGcgTc22AY.1080.002205
ORF3a49G49VgGcgTc22AY.210.003795
ORF3a49G49VgGcgTc22AY.220.004184
ORF3a49G49VgGcgTc22AY.270.000129
ORF3a49G49VgGcgTc22AY.350.000466
ORF3a49G49VgGcgTc22AY.39.10.000079
ORF3a49G49VgGcgTc22AY.4.40.000818
ORF3a49G49VgGcgTc22AY.570.001312
ORF3a49G49VgGcgTc22AY.960.004149
ORF3a49G49VgGcgTc22B.1.1.100.00223
ORF3a49G49VgGcgTc22B.1.1.3110.000716
ORF3a49G49VgGcgTc22B.1.1.3170.000823
ORF3a49G49VgGcgTc22B.1.1.330.000842
ORF3a49G49VgGcgTc22B.1.2450.0625
ORF3a49G49VgGcgTc22B.1.36.170.000988
ORF3a49G49VgGcgTc22B.1.3750.001639
ORF3a49G49VgGcgTc22B.1.5090.001732
ORF3a49G49VgGcgTc22B.1.5260.000047
ORF3a49G49VgGcgTc22B.1.5650.001621
ORF3a49G49VgGcgTc22B.1.5960.000174
ORF3a49G49VgGcgTc22B.1.6210.000177
ORF3a49G49VgGcgTc22B.1.6370.000146
ORF3a49G49VgGcgTc22D.20.00015
ORF3a49G49VgGcgTc22N.30.011628
ORF3a49G49VgGcgTc22P.1.100.000539
ORF3a49G49VgGcgTc22P.20.000373
ORF3a49G49VgGcgTc22R.10.00018
ORF3a49G49VgGcgTc11A0.000387
ORF3a49G49VgGcgTc11A.20.000662
ORF3a49G49VgGcgTc11AD.20.000219
ORF3a49G49VgGcgTc11AY.1090.00074
ORF3a49G49VgGcgTc11AY.120.000316
ORF3a49G49VgGcgTc11AY.140.000088
ORF3a49G49VgGcgTc11AY.190.00114
ORF3a49G49VgGcgTc11AY.380.000499
ORF3a49G49VgGcgTc11AY.480.000465
ORF3a49G49VgGcgTc11AY.670.000464
ORF3a49G49VgGcgTc11AY.690.000187
ORF3a49G49VgGcgTc11AY.710.000475
ORF3a49G49VgGcgTc11AY.790.001211
ORF3a49G49VgGcgTc11AY.880.000884
ORF3a49G49VgGcgTc11AY.900.000684
ORF3a49G49VgGcgTc11AY.99.10.001553
ORF3a49G49VgGcgTc11AY.99.20.000092
ORF3a49G49VgGcgTc11AZ.20.000821
ORF3a49G49VgGcgTc11B0.000128
ORF3a49G49VgGcgTc11B.1.1.10.000327
ORF3a49G49VgGcgTc11B.1.1.250.000569
ORF3a49G49VgGcgTc11B.1.1.280.000311
ORF3a49G49VgGcgTc11B.1.1.3490.010309
ORF3a49G49VgGcgTc11B.1.1.370.000193
ORF3a49G49VgGcgTc11B.1.1.4340.000349
ORF3a49G49VgGcgTc11B.1.1.460.004367
ORF3a49G49VgGcgTc11B.1.1.520.012195
ORF3a49G49VgGcgTc11B.1.1690.014925
ORF3a49G49VgGcgTc11B.1.177.230.003236
ORF3a49G49VgGcgTc11B.1.177.870.000728
ORF3a49G49VgGcgTc11B.1.2100.002132
ORF3a49G49VgGcgTc11B.1.243.10.022222
ORF3a49G49VgGcgTc11B.1.2580.000067
ORF3a49G49VgGcgTc11B.1.360.000146
ORF3a49G49VgGcgTc11B.1.36.10.00114
ORF3a49G49VgGcgTc11B.1.36.250.002208
ORF3a49G49VgGcgTc11B.1.3670.000792
ORF3a49G49VgGcgTc11B.1.3980.002976
ORF3a49G49VgGcgTc11B.1.4000.000429
ORF3a49G49VgGcgTc11B.1.416.10.001563
ORF3a49G49VgGcgTc11B.1.438.10.000107
ORF3a49G49VgGcgTc11B.1.4590.004082
ORF3a49G49VgGcgTc11B.1.466.20.000391
ORF3a49G49VgGcgTc11B.1.4680.005714
ORF3a49G49VgGcgTc11B.1.5620.018519
ORF3a49G49VgGcgTc11B.1.5740.002151
ORF3a49G49VgGcgTc11B.1.5750.000303
ORF3a49G49VgGcgTc11B.1.5770.000687
ORF3a49G49VgGcgTc11B.1.5970.00463
ORF3a49G49VgGcgTc11B.1.6190.000871
ORF3a49G49VgGcgTc11B.1.6290.013333
ORF3a49G49VgGcgTc11B.1.6390.021739
ORF3a49G49VgGcgTc11N.90.005952
ORF3a49G49VgGcgTc11P.1.120.000484
ORF3a49G49VgGcgTc11P.1.140.000048
ORF3a49G49VgGcgTc11P.1.70.000319

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

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