CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF3a : Mut = G254V

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF3a254G254VnonsyngGagTa293929370.99931926152-26154
ORF3a254G254VnonsyngGAgTG293910.00034025226152-26154
ORF3a254G254VnonsyngGAgTT293910.00034025226152-26154

Details of the mutation G254V within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF3a254G254VgGagTa29372939All0.000562
ORF3a254G254VgGAgTG12939All0
ORF3a254G254VgGAgTT12939All0
ORF3a254G254VgGagTa663663AY.40.001032
ORF3a254G254VgGagTa635635AY.1030.003943
ORF3a254G254VgGagTa605606B.1.1.70.000542
ORF3a254G254VgGAgTG1606B.1.1.70.000001
ORF3a254G254VgGagTa213213B.1.1.2220.043452
ORF3a254G254VgGagTa9696B.1.1.2360.662069
ORF3a254G254VgGagTa8181AY.430.000359
ORF3a254G254VgGagTa5555B.1.617.20.000207
ORF3a254G254VgGagTa4848P.10.000756
ORF3a254G254VgGagTa3636B.1.6020.235294
ORF3a254G254VgGagTa3434AY.250.000205
ORF3a254G254VgGagTa3434B.1.1770.000448
ORF3a254G254VgGagTa3031B.1.10.000544
ORF3a254G254VgGAgTT131B.1.10.000018
ORF3a254G254VgGagTa3131B.1.1260.039541
ORF3a254G254VgGagTa3030B.10.000275
ORF3a254G254VgGagTa1717AY.440.000103
ORF3a254G254VgGagTa1717B.1.6210.001505
ORF3a254G254VgGagTa1414B.1.20.000123
ORF3a254G254VgGagTa1313AY.470.000404
ORF3a254G254VgGagTa1313B.1.1.500.008826
ORF3a254G254VgGagTa1111AY.390.000272
ORF3a254G254VgGagTa1010AY.1020.000265
ORF3a254G254VgGagTa99AY.30.00009
ORF3a254G254VgGagTa99AY.4.50.000967
ORF3a254G254VgGagTa99AY.50.000186
ORF3a254G254VgGagTa99B.1.6230.004828
ORF3a254G254VgGagTa88AY.1200.000297
ORF3a254G254VgGagTa88AY.130.001288
ORF3a254G254VgGagTa88P.1.140.000382
ORF3a254G254VgGagTa77AY.4.20.000152
ORF3a254G254VgGagTa77B.1.2210.000497
ORF3a254G254VgGagTa66AY.1000.000276
ORF3a254G254VgGagTa66AY.9.20.00022
ORF3a254G254VgGagTa66B.1.5960.000523
ORF3a254G254VgGagTa55AY.230.000349
ORF3a254G254VgGagTa55AY.420.000201
ORF3a254G254VgGagTa55B.1.1.3480.003981
ORF3a254G254VgGagTa55B.1.1.5190.000199
ORF3a254G254VgGagTa55B.1.360.00073
ORF3a254G254VgGagTa55B.1.5260.000118
ORF3a254G254VgGagTa44AY.200.000155
ORF3a254G254VgGagTa44AY.290.000063
ORF3a254G254VgGagTa33AY.330.0002
ORF3a254G254VgGagTa33AY.770.003382
ORF3a254G254VgGagTa33AY.980.000237
ORF3a254G254VgGagTa33B.1.1.1940.014851
ORF3a254G254VgGagTa33B.1.1.2140.000166
ORF3a254G254VgGagTa33B.1.1.3120.005736
ORF3a254G254VgGagTa33B.1.2580.0002
ORF3a254G254VgGagTa33B.1.4000.001287
ORF3a254G254VgGagTa33B.1.4290.000071
ORF3a254G254VgGagTa33B.1.6280.001057
ORF3a254G254VgGagTa22A0.000774
ORF3a254G254VgGagTa22A.2.50.000998
ORF3a254G254VgGagTa22AY.1180.000125
ORF3a254G254VgGagTa22AY.1210.000271
ORF3a254G254VgGagTa22AY.370.000632
ORF3a254G254VgGagTa22AY.4.2.10.000298
ORF3a254G254VgGagTa22AY.5.30.000675
ORF3a254G254VgGagTa22AY.90.000135
ORF3a254G254VgGagTa22B.1.1.2510.015873
ORF3a254G254VgGagTa22B.1.1600.000062
ORF3a254G254VgGagTa22B.1.177.210.000153
ORF3a254G254VgGagTa22B.1.2430.000139
ORF3a254G254VgGagTa22B.1.258.170.000208
ORF3a254G254VgGagTa22B.1.3510.000059
ORF3a254G254VgGagTa22B.1.5440.012048
ORF3a254G254VgGagTa22B.1.5820.000981
ORF3a254G254VgGagTa22C.180.005181
ORF3a254G254VgGagTa22Q.80.00033
ORF3a254G254VgGagTa11AY.1070.000466
ORF3a254G254VgGagTa11AY.1080.001103
ORF3a254G254VgGagTa11AY.1170.000085
ORF3a254G254VgGagTa11AY.16.10.00047
ORF3a254G254VgGagTa11AY.210.001898
ORF3a254G254VgGagTa11AY.260.000028
ORF3a254G254VgGagTa11AY.3.10.000085
ORF3a254G254VgGagTa11AY.340.000097
ORF3a254G254VgGagTa11AY.360.000148
ORF3a254G254VgGagTa11AY.39.10.00004
ORF3a254G254VgGagTa11AY.410.000294
ORF3a254G254VgGagTa11AY.450.000122
ORF3a254G254VgGagTa11AY.46.60.000072
ORF3a254G254VgGagTa11AY.510.000909
ORF3a254G254VgGagTa11AY.60.000041
ORF3a254G254VgGagTa11AY.610.000105
ORF3a254G254VgGagTa11AY.650.000533
ORF3a254G254VgGagTa11AY.750.000056
ORF3a254G254VgGagTa11AY.9.10.000084
ORF3a254G254VgGagTa11AY.900.000684
ORF3a254G254VgGagTa11AY.910.00073
ORF3a254G254VgGagTa11AY.98.10.000048
ORF3a254G254VgGagTa11B.1.1.1610.003534
ORF3a254G254VgGagTa11B.1.1.2070.001182
ORF3a254G254VgGagTa11B.1.1.2940.001266
ORF3a254G254VgGagTa11B.1.1.3160.000925
ORF3a254G254VgGagTa11B.1.1.3170.000412
ORF3a254G254VgGagTa11B.1.1.3220.008772
ORF3a254G254VgGagTa11B.1.1.3260.001761
ORF3a254G254VgGagTa11B.1.1.330.000421
ORF3a254G254VgGagTa11B.1.1.4170.002703
ORF3a254G254VgGagTa11B.1.1.4340.000349
ORF3a254G254VgGagTa11B.1.177.730.000566
ORF3a254G254VgGagTa11B.1.177.830.001481
ORF3a254G254VgGagTa11B.1.2100.002132
ORF3a254G254VgGagTa11B.1.2340.000132
ORF3a254G254VgGagTa11B.1.3130.006579
ORF3a254G254VgGagTa11B.1.351.20.000303
ORF3a254G254VgGagTa11B.1.36.290.000517
ORF3a254G254VgGagTa11B.1.4270.00005
ORF3a254G254VgGagTa11B.1.466.20.000391
ORF3a254G254VgGagTa11B.1.5300.007143
ORF3a254G254VgGagTa11B.1.5610.000397
ORF3a254G254VgGagTa11B.1.5680.001111
ORF3a254G254VgGagTa11B.1.5800.004065
ORF3a254G254VgGagTa11B.1.6190.000871
ORF3a254G254VgGagTa11B.1.621.10.000506
ORF3a254G254VgGagTa11B.1.88.10.004808
ORF3a254G254VgGagTa11B.1.930.000934
ORF3a254G254VgGagTa11C.370.000116
ORF3a254G254VgGagTa11N.50.001767
ORF3a254G254VgGagTa11P.1.150.000232
ORF3a254G254VgGagTa11P.1.160.000374
ORF3a254G254VgGagTa11P.20.000187
ORF3a254G254VgGagTa11Q.60.006623

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

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