CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF3a : Mut = G251V

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF3a251G251VnonsyngGtgTt807480690.99938126143-26145
ORF3a251G251VnonsyngGTgTA807430.00037156326143-26145
ORF3a251G251VnonsyngGTgTG807420.00024770926143-26145

Details of the mutation G251V within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF3a251G251VgGtgTt80698074All0.001543
ORF3a251G251VgGTgTA38074All0.000001
ORF3a251G251VgGTgTG28074All0
ORF3a251G251VgGtgTt27532753B0.351866
ORF3a251G251VgGtgTt26582658B.400.968306
ORF3a251G251VgGtgTt421421B.390.981352
ORF3a251G251VgGtgTt299299B.280.980328
ORF3a251G251VgGtgTt277277B.290.97193
ORF3a251G251VgGtgTt258258B.310.962687
ORF3a251G251VgGtgTt183183B.1.4990.192227
ORF3a251G251VgGtgTt171171B.610.982759
ORF3a251G251VgGtgTt125125B.350.976562
ORF3a251G251VgGtgTt124124B.410.992
ORF3a251G251VgGtgTt9595B.580.969388
ORF3a251G251VgGtgTt7272B.340.986301
ORF3a251G251VgGtgTt6969B.430.985714
ORF3a251G251VgGtgTt6767B.300.985294
ORF3a251G251VgGtgTt6161B.600.968254
ORF3a251G251VgGtgTt4646B.330.978723
ORF3a251G251VgGtgTt4242B.381
ORF3a251G251VgGtgTt3940B.10.000357
ORF3a251G251VgGTgTA140B.10.000009
ORF3a251G251VgGtgTt3939AY.1030.000242
ORF3a251G251VgGtgTt3737B.321
ORF3a251G251VgGtgTt3333B.370.942857
ORF3a251G251VgGtgTt3030B.421
ORF3a251G251VgGtgTt1818AY.40.000028
ORF3a251G251VgGtgTt1616B.1.1.70.000014
ORF3a251G251VgGtgTt1313B.361
ORF3a251G251VgGtgTt1212B.1.10.000218
ORF3a251G251VgGtgTt1010B.441
ORF3a251G251VgGtgTt77B.1.617.20.000026
ORF3a251G251VgGtgTt77B.550.020649
ORF3a251G251VgGtgTt55AY.90.000338
ORF3a251G251VgGTgTG240.111111
ORF3a251G251VgGTgTA240.111111
ORF3a251G251VgGtgTt44AY.250.000024
ORF3a251G251VgGtgTt44AY.440.000024
ORF3a251G251VgGtgTt44B.1.6210.000354
ORF3a251G251VgGtgTt33B.1.1770.00004
ORF3a251G251VgGtgTt33B.1.20.000026
ORF3a251G251VgGtgTt33B.1.4970.000944
ORF3a251G251VgGtgTt22A0.000774
ORF3a251G251VgGtgTt22A.20.001324
ORF3a251G251VgGtgTt22AY.30.00002
ORF3a251G251VgGtgTt22AY.300.000791
ORF3a251G251VgGtgTt22AY.360.000296
ORF3a251G251VgGtgTt22AY.4.20.000043
ORF3a251G251VgGtgTt22AY.470.000062
ORF3a251G251VgGtgTt22B.1.1.1610.007067
ORF3a251G251VgGtgTt22B.1.1570.00597
ORF3a251G251VgGtgTt22B.1.4290.000047
ORF3a251G251VgGtgTt22B.230.005848
ORF3a251G251VgGtgTt22B.30.001661
ORF3a251G251VgGtgTt22B.40.004415
ORF3a251G251VgGtgTt22P.10.000032
ORF3a251G251VgGtgTt11A.2.20.001689
ORF3a251G251VgGtgTt11A.2.30.004739
ORF3a251G251VgGtgTt11A.2.50.000499
ORF3a251G251VgGtgTt11A.50.001923
ORF3a251G251VgGtgTt11AY.1170.000085
ORF3a251G251VgGtgTt11AY.1190.000035
ORF3a251G251VgGtgTt11AY.200.000039
ORF3a251G251VgGtgTt11AY.380.000499
ORF3a251G251VgGtgTt11AY.430.000004
ORF3a251G251VgGtgTt11AY.620.000436
ORF3a251G251VgGtgTt11AY.680.000274
ORF3a251G251VgGtgTt11AY.690.000187
ORF3a251G251VgGtgTt11B.1.1.3060.000438
ORF3a251G251VgGtgTt11B.1.1.3110.000358
ORF3a251G251VgGtgTt11B.1.1.330.000421
ORF3a251G251VgGtgTt11B.1.1.4670.019231
ORF3a251G251VgGtgTt11B.1.1.890.006061
ORF3a251G251VgGtgTt11B.1.1420.002899
ORF3a251G251VgGtgTt11B.1.1460.004237
ORF3a251G251VgGtgTt11B.1.177.440.000519
ORF3a251G251VgGtgTt11B.1.2150.009615
ORF3a251G251VgGtgTt11B.1.2210.000071
ORF3a251G251VgGtgTt11B.1.3360.002439
ORF3a251G251VgGtgTt11B.1.3510.00003
ORF3a251G251VgGtgTt11B.1.360.000146
ORF3a251G251VgGtgTt11B.1.4230.010204
ORF3a251G251VgGtgTt11B.1.5030.002488
ORF3a251G251VgGtgTt11B.4.70.010101
ORF3a251G251VgGtgTt11B.470.020408
ORF3a251G251VgGtgTt11C.350.000774
ORF3a251G251VgGtgTt11D.20.000075
ORF3a251G251VgGtgTt11P.1.70.000319
ORF3a251G251VgGtgTt11Q.80.000165

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

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