CoV-GLUE | Mutations | Mutation
CoV-GLUE Mutation: ORF = ORF3a : Mut = E19del
Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):
| ORF | CodonNum | Mut | ORF1abMut | MutType | RefCodon | MutCodon | AACount | CodonCount | CodonProp | Genome Position |
| ORF3a | 19 | E19del | del | GAA | --- | 1852 | 1852 | 1 | 25447-25449 |
Details of the mutation E19del within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):
| ORF | CodonNum | Mut | RefCodon | MutCodon | CodonCount | AACount | Lineage | LineageCodonProp |
| ORF3a | 19 | E19del | GAA | --- | 1852 | 1852 | All | 0.000354 |
| ORF3a | 19 | E19del | GAA | --- | 1239 | 1239 | B.1.214.2 | 0.742806 |
| ORF3a | 19 | E19del | GAA | --- | 151 | 151 | B.1.1.7 | 0.000135 |
| ORF3a | 19 | E19del | GAA | --- | 77 | 77 | AY.44 | 0.000469 |
| ORF3a | 19 | E19del | GAA | --- | 57 | 57 | B.1.2 | 0.000502 |
| ORF3a | 19 | E19del | GAA | --- | 30 | 30 | AY.4 | 0.000047 |
| ORF3a | 19 | E19del | GAA | --- | 24 | 24 | B.1 | 0.00022 |
| ORF3a | 19 | E19del | GAA | --- | 24 | 24 | B.1.177.60 | 0.005242 |
| ORF3a | 19 | E19del | GAA | --- | 18 | 18 | B.1.617.2 | 0.000068 |
| ORF3a | 19 | E19del | GAA | --- | 18 | 18 | P.1 | 0.000284 |
| ORF3a | 19 | E19del | GAA | --- | 14 | 14 | B.1.177 | 0.000184 |
| ORF3a | 19 | E19del | GAA | --- | 10 | 10 | AY.29 | 0.000158 |
| ORF3a | 19 | E19del | GAA | --- | 9 | 9 | AY.43 | 0.00004 |
| ORF3a | 19 | E19del | GAA | --- | 9 | 9 | B.1.210 | 0.01919 |
| ORF3a | 19 | E19del | GAA | --- | 9 | 9 | B.1.639 | 0.195652 |
| ORF3a | 19 | E19del | GAA | --- | 8 | 8 | AY.4.5 | 0.00086 |
| ORF3a | 19 | E19del | GAA | --- | 8 | 8 | B.1.1.519 | 0.000318 |
| ORF3a | 19 | E19del | GAA | --- | 8 | 8 | B.1.429 | 0.000188 |
| ORF3a | 19 | E19del | GAA | --- | 7 | 7 | B.1.1 | 0.000127 |
| ORF3a | 19 | E19del | GAA | --- | 7 | 7 | B.1.1.317 | 0.002882 |
| ORF3a | 19 | E19del | GAA | --- | 6 | 6 | P.1.14 | 0.000287 |
| ORF3a | 19 | E19del | GAA | --- | 5 | 5 | AY.103 | 0.000031 |
| ORF3a | 19 | E19del | GAA | --- | 5 | 5 | AY.25 | 0.00003 |
| ORF3a | 19 | E19del | GAA | --- | 5 | 5 | B.1.214.3 | 0.035714 |
| ORF3a | 19 | E19del | GAA | --- | 5 | 5 | B.1.36.29 | 0.002587 |
| ORF3a | 19 | E19del | GAA | --- | 4 | 4 | AY.26 | 0.000113 |
| ORF3a | 19 | E19del | GAA | --- | 4 | 4 | B.1.214 | 0.014652 |
| ORF3a | 19 | E19del | GAA | --- | 4 | 4 | B.1.214.1 | 0.08 |
| ORF3a | 19 | E19del | GAA | --- | 3 | 3 | AY.46.2 | 0.001906 |
| ORF3a | 19 | E19del | GAA | --- | 3 | 3 | AY.5 | 0.000062 |
| ORF3a | 19 | E19del | GAA | --- | 3 | 3 | B.1.221 | 0.000213 |
| ORF3a | 19 | E19del | GAA | --- | 3 | 3 | Q.1 | 0.000379 |
| ORF3a | 19 | E19del | GAA | --- | 3 | 3 | U.3 | 0.011583 |
| ORF3a | 19 | E19del | GAA | --- | 2 | 2 | AY.111 | 0.000366 |
| ORF3a | 19 | E19del | GAA | --- | 2 | 2 | AY.118 | 0.000125 |
| ORF3a | 19 | E19del | GAA | --- | 2 | 2 | AY.27 | 0.000129 |
| ORF3a | 19 | E19del | GAA | --- | 2 | 2 | AY.39 | 0.000049 |
| ORF3a | 19 | E19del | GAA | --- | 2 | 2 | AY.47 | 0.000062 |
| ORF3a | 19 | E19del | GAA | --- | 2 | 2 | AY.6 | 0.000082 |
| ORF3a | 19 | E19del | GAA | --- | 2 | 2 | AY.79 | 0.002421 |
| ORF3a | 19 | E19del | GAA | --- | 2 | 2 | B.1.1.214 | 0.000111 |
| ORF3a | 19 | E19del | GAA | --- | 2 | 2 | B.1.177.4 | 0.000422 |
| ORF3a | 19 | E19del | GAA | --- | 2 | 2 | B.1.409 | 0.001563 |
| ORF3a | 19 | E19del | GAA | --- | 2 | 2 | B.1.427 | 0.000101 |
| ORF3a | 19 | E19del | GAA | --- | 1 | 1 | A.2.5 | 0.000499 |
| ORF3a | 19 | E19del | GAA | --- | 1 | 1 | A.23.1 | 0.000704 |
| ORF3a | 19 | E19del | GAA | --- | 1 | 1 | AY.105 | 0.000643 |
| ORF3a | 19 | E19del | GAA | --- | 1 | 1 | AY.117 | 0.000085 |
| ORF3a | 19 | E19del | GAA | --- | 1 | 1 | AY.120 | 0.000037 |
| ORF3a | 19 | E19del | GAA | --- | 1 | 1 | AY.19 | 0.00114 |
| ORF3a | 19 | E19del | GAA | --- | 1 | 1 | AY.20 | 0.000039 |
| ORF3a | 19 | E19del | GAA | --- | 1 | 1 | AY.23 | 0.00007 |
| ORF3a | 19 | E19del | GAA | --- | 1 | 1 | AY.3.1 | 0.000085 |
| ORF3a | 19 | E19del | GAA | --- | 1 | 1 | AY.33 | 0.000067 |
| ORF3a | 19 | E19del | GAA | --- | 1 | 1 | AY.39.1 | 0.00004 |
| ORF3a | 19 | E19del | GAA | --- | 1 | 1 | AY.5.4 | 0.000277 |
| ORF3a | 19 | E19del | GAA | --- | 1 | 1 | AY.54 | 0.000095 |
| ORF3a | 19 | E19del | GAA | --- | 1 | 1 | AY.60 | 0.000938 |
| ORF3a | 19 | E19del | GAA | --- | 1 | 1 | AY.68 | 0.000274 |
| ORF3a | 19 | E19del | GAA | --- | 1 | 1 | AY.9 | 0.000068 |
| ORF3a | 19 | E19del | GAA | --- | 1 | 1 | AY.9.2 | 0.000037 |
| ORF3a | 19 | E19del | GAA | --- | 1 | 1 | AY.98 | 0.000079 |
| ORF3a | 19 | E19del | GAA | --- | 1 | 1 | AY.98.1 | 0.000048 |
| ORF3a | 19 | E19del | GAA | --- | 1 | 1 | AY.99 | 0.001049 |
| ORF3a | 19 | E19del | GAA | --- | 1 | 1 | B.1.1.139 | 0.022727 |
| ORF3a | 19 | E19del | GAA | --- | 1 | 1 | B.1.1.216 | 0.00089 |
| ORF3a | 19 | E19del | GAA | --- | 1 | 1 | B.1.1.409 | 0.002833 |
| ORF3a | 19 | E19del | GAA | --- | 1 | 1 | B.1.1.63 | 0.000386 |
| ORF3a | 19 | E19del | GAA | --- | 1 | 1 | B.1.142 | 0.002899 |
| ORF3a | 19 | E19del | GAA | --- | 1 | 1 | B.1.160.33 | 0.004425 |
| ORF3a | 19 | E19del | GAA | --- | 1 | 1 | B.1.177.11 | 0.001698 |
| ORF3a | 19 | E19del | GAA | --- | 1 | 1 | B.1.177.19 | 0.001431 |
| ORF3a | 19 | E19del | GAA | --- | 1 | 1 | B.1.177.6 | 0.000977 |
| ORF3a | 19 | E19del | GAA | --- | 1 | 1 | B.1.177.7 | 0.000165 |
| ORF3a | 19 | E19del | GAA | --- | 1 | 1 | B.1.177.76 | 0.002494 |
| ORF3a | 19 | E19del | GAA | --- | 1 | 1 | B.1.179 | 0.003759 |
| ORF3a | 19 | E19del | GAA | --- | 1 | 1 | B.1.221.1 | 0.002907 |
| ORF3a | 19 | E19del | GAA | --- | 1 | 1 | B.1.258 | 0.000067 |
| ORF3a | 19 | E19del | GAA | --- | 1 | 1 | B.1.258.10 | 0.011364 |
| ORF3a | 19 | E19del | GAA | --- | 1 | 1 | B.1.351 | 0.00003 |
| ORF3a | 19 | E19del | GAA | --- | 1 | 1 | B.1.36.17 | 0.000494 |
| ORF3a | 19 | E19del | GAA | --- | 1 | 1 | B.1.36.18 | 0.00042 |
| ORF3a | 19 | E19del | GAA | --- | 1 | 1 | B.1.36.31 | 0.001751 |
| ORF3a | 19 | E19del | GAA | --- | 1 | 1 | B.1.389 | 0.001002 |
| ORF3a | 19 | E19del | GAA | --- | 1 | 1 | B.1.459 | 0.004082 |
| ORF3a | 19 | E19del | GAA | --- | 1 | 1 | B.1.526 | 0.000024 |
| ORF3a | 19 | E19del | GAA | --- | 1 | 1 | B.1.595 | 0.000261 |
| ORF3a | 19 | E19del | GAA | --- | 1 | 1 | B.1.609 | 0.000479 |
| ORF3a | 19 | E19del | GAA | --- | 1 | 1 | B.1.619 | 0.000871 |
| ORF3a | 19 | E19del | GAA | --- | 1 | 1 | B.1.628 | 0.000352 |
| ORF3a | 19 | E19del | GAA | --- | 1 | 1 | B.1.638 | 0.052632 |
| ORF3a | 19 | E19del | GAA | --- | 1 | 1 | B.3.1 | 0.001658 |
| ORF3a | 19 | E19del | GAA | --- | 1 | 1 | B.55 | 0.00295 |
| ORF3a | 19 | E19del | GAA | --- | 1 | 1 | P.1.15 | 0.000232 |
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CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk
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