CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF3a : Mut = D173E

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF3a173D173EnonsyngaTgaA76590.77631625909-25911
ORF3a173D173EnonsyngaTgaG76170.22368425909-25911

Details of the mutation D173E within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF3a173D173EgaTgaA5976All0.000011
ORF3a173D173EgaTgaG1776All0.000003
ORF3a173D173EgaTgaA3234B.1.1.70.000029
ORF3a173D173EgaTgaG234B.1.1.70.000002
ORF3a173D173EgaTgaA77AY.30.00007
ORF3a173D173EgaTgaA55B.1.1.3720.003444
ORF3a173D173EgaTgaA23B.1.617.20.000008
ORF3a173D173EgaTgaG13B.1.617.20.000004
ORF3a173D173EgaTgaG22AY.1180.000125
ORF3a173D173EgaTgaA22AY.430.000009
ORF3a173D173EgaTgaG22B.1.10.000036
ORF3a173D173EgaTgaA22B.1.1.3180.000604
ORF3a173D173EgaTgaG11AY.110.001339
ORF3a173D173EgaTgaA11AY.230.00007
ORF3a173D173EgaTgaA11AY.250.000006
ORF3a173D173EgaTgaA11AY.300.000396
ORF3a173D173EgaTgaG11AY.40.000002
ORF3a173D173EgaTgaG11AY.4.20.000022
ORF3a173D173EgaTgaA11AY.440.000006
ORF3a173D173EgaTgaG11AY.60.000041
ORF3a173D173EgaTgaA11B.1.1.2220.000204
ORF3a173D173EgaTgaG11B.1.1.4300.041667
ORF3a173D173EgaTgaG11B.1.1.5190.00004
ORF3a173D173EgaTgaA11B.1.2790.000514
ORF3a173D173EgaTgaG11B.1.4270.00005
ORF3a173D173EgaTgaG11B.1.4620.007246
ORF3a173D173EgaTgaG11B.1.4970.000315
ORF3a173D173EgaTgaG11B.1.5640.000426
ORF3a173D173EgaTgaA11B.1.5880.00091
ORF3a173D173EgaTgaA11B.1.6060.006024
ORF3a173D173EgaTgaA11C.370.000116

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.