CoV-GLUE | Mutations | Mutation
Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):
ORF | CodonNum | Mut | ORF1abMut | MutType | RefCodon | MutCodon | AACount | CodonCount | CodonProp | Genome Position |
ORF3a | 86 | L86F | nonsyn | ttG | ttT | 3938 | 3906 | 0.991874 | 25648-25650 |
Details of the mutation no within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):
ORF | CodonNum | Mut | RefCodon | MutCodon | CodonCount | AACount | Lineage | LineageCodonProp |
ORF3a | 86 | L86F | ttG | ttT | 3906 | 3938 | All | 0.000747 |
ORF3a | 86 | L86F | ttG | ttT | 632 | 637 | B.1.1.7 | 0.000566 |
ORF3a | 86 | L86F | ttG | ttT | 612 | 613 | AY.4 | 0.000953 |
ORF3a | 86 | L86F | ttG | ttT | 424 | 424 | B.1.298 | 0.896406 |
ORF3a | 86 | L86F | ttG | ttT | 234 | 234 | AY.91.1 | 0.95122 |
ORF3a | 86 | L86F | ttG | ttT | 163 | 163 | B.1.351.2 | 0.049319 |
ORF3a | 86 | L86F | ttG | ttT | 142 | 143 | B.1.617.2 | 0.000535 |
ORF3a | 86 | L86F | ttG | ttT | 125 | 127 | AY.43 | 0.000554 |
ORF3a | 86 | L86F | ttG | ttT | 93 | 93 | AY.25 | 0.000559 |
ORF3a | 86 | L86F | ttG | ttT | 87 | 87 | AY.91 | 0.06355 |
ORF3a | 86 | L86F | ttG | ttT | 75 | 75 | AY.44 | 0.000457 |
ORF3a | 86 | L86F | ttG | ttT | 73 | 73 | AY.102 | 0.001936 |
ORF3a | 86 | L86F | ttG | ttT | 70 | 70 | B.1.575 | 0.021238 |
ORF3a | 86 | L86F | ttG | ttT | 67 | 67 | AY.103 | 0.000416 |
ORF3a | 86 | L86F | ttG | ttT | 65 | 66 | B.1.2 | 0.000572 |
ORF3a | 86 | L86F | ttG | ttT | 64 | 64 | P.1 | 0.001008 |
ORF3a | 86 | L86F | ttG | ttT | 60 | 60 | B.1.429 | 0.001412 |
ORF3a | 86 | L86F | ttG | ttT | 56 | 56 | B.1.596 | 0.00488 |
ORF3a | 86 | L86F | ttG | ttT | 45 | 48 | B.1 | 0.000412 |
ORF3a | 86 | L86F | ttG | ttT | 48 | 48 | B.1.35 | 0.40678 |
ORF3a | 86 | L86F | ttG | ttT | 38 | 40 | B.1.1 | 0.000689 |
ORF3a | 86 | L86F | ttG | ttT | 33 | 33 | B.1.160 | 0.001029 |
ORF3a | 86 | L86F | ttG | ttT | 30 | 31 | AY.3 | 0.000298 |
ORF3a | 86 | L86F | ttG | ttT | 30 | 30 | B.1.526 | 0.000705 |
ORF3a | 86 | L86F | ttG | ttT | 28 | 28 | AY.26 | 0.000793 |
ORF3a | 86 | L86F | ttG | ttT | 24 | 24 | AY.4.2 | 0.000521 |
ORF3a | 86 | L86F | ttG | ttT | 23 | 23 | AY.39 | 0.000568 |
ORF3a | 86 | L86F | ttG | ttT | 20 | 20 | AY.47 | 0.000622 |
ORF3a | 86 | L86F | ttG | ttT | 19 | 20 | B.1.525 | 0.00215 |
ORF3a | 86 | L86F | ttG | ttT | 19 | 19 | L.2 | 0.215909 |
ORF3a | 86 | L86F | ttG | ttT | 17 | 18 | AY.119 | 0.0006 |
ORF3a | 86 | L86F | ttG | ttT | 15 | 15 | B.1.177 | 0.000198 |
ORF3a | 86 | L86F | ttG | ttT | 15 | 15 | B.1.351 | 0.000446 |
ORF3a | 86 | L86F | ttG | ttT | 14 | 14 | AY.29 | 0.000221 |
ORF3a | 86 | L86F | ttG | ttT | 14 | 14 | AY.98 | 0.001106 |
ORF3a | 86 | L86F | ttG | ttT | 14 | 14 | B.1.631 | 0.047138 |
ORF3a | 86 | L86F | ttG | ttT | 11 | 11 | AY.100 | 0.000506 |
ORF3a | 86 | L86F | ttG | ttT | 11 | 11 | AY.9.1 | 0.000921 |
ORF3a | 86 | L86F | ttG | ttT | 11 | 11 | B.1.427 | 0.000555 |
ORF3a | 86 | L86F | ttG | ttT | 11 | 11 | B.1.609 | 0.005273 |
ORF3a | 86 | L86F | ttG | ttT | 10 | 10 | AY.20 | 0.000389 |
ORF3a | 86 | L86F | ttG | ttT | 10 | 10 | C.37 | 0.001161 |
ORF3a | 86 | L86F | ttG | ttT | 9 | 9 | B.1.177.57 | 0.002529 |
ORF3a | 86 | L86F | ttG | ttT | 4 | 8 | AY.33 | 0.000267 |
ORF3a | 86 | L86F | ttG | ttT | 8 | 8 | AY.6 | 0.000329 |
ORF3a | 86 | L86F | ttG | ttT | 8 | 8 | B.1.400 | 0.003432 |
ORF3a | 86 | L86F | ttG | ttT | 7 | 7 | AY.5 | 0.000145 |
ORF3a | 86 | L86F | ttG | ttT | 7 | 7 | AY.7.1 | 0.000789 |
ORF3a | 86 | L86F | ttG | ttT | 7 | 7 | B.1.1.348 | 0.005573 |
ORF3a | 86 | L86F | ttG | ttT | 7 | 7 | B.1.177.86 | 0.001284 |
ORF3a | 86 | L86F | ttG | ttT | 7 | 7 | B.1.404 | 0.009115 |
ORF3a | 86 | L86F | ttG | ttT | 7 | 7 | C.1.1 | 0.538462 |
ORF3a | 86 | L86F | ttG | ttT | 7 | 7 | P.1.15 | 0.001626 |
ORF3a | 86 | L86F | ttG | ttT | 7 | 7 | P.2 | 0.001306 |
ORF3a | 86 | L86F | ttG | ttT | 5 | 6 | AY.98.1 | 0.000242 |
ORF3a | 86 | L86F | ttG | ttT | 6 | 6 | B.1.1.306 | 0.00263 |
ORF3a | 86 | L86F | ttG | ttT | 6 | 6 | B.1.567 | 0.02 |
ORF3a | 86 | L86F | ttG | ttT | 6 | 6 | P.1.14 | 0.000287 |
ORF3a | 86 | L86F | ttG | ttT | 6 | 6 | Q.3 | 0.00087 |
ORF3a | 86 | L86F | ttG | ttT | 5 | 5 | AY.120 | 0.000186 |
ORF3a | 86 | L86F | ttG | ttT | 5 | 5 | AY.3.1 | 0.000426 |
ORF3a | 86 | L86F | ttG | ttT | 5 | 5 | AY.61 | 0.000524 |
ORF3a | 86 | L86F | ttG | ttT | 5 | 5 | B.1.1.28 | 0.001556 |
ORF3a | 86 | L86F | ttG | ttT | 5 | 5 | B.1.1.33 | 0.002104 |
ORF3a | 86 | L86F | ttG | ttT | 5 | 5 | B.1.466.2 | 0.001956 |
ORF3a | 86 | L86F | ttG | ttT | 4 | 4 | AY.113 | 0.00057 |
ORF3a | 86 | L86F | ttG | ttT | 4 | 4 | AY.117 | 0.000338 |
ORF3a | 86 | L86F | ttG | ttT | 4 | 4 | AY.121 | 0.000541 |
ORF3a | 86 | L86F | ttG | ttT | 4 | 4 | AY.23 | 0.000279 |
ORF3a | 86 | L86F | ttG | ttT | 4 | 4 | AY.36 | 0.000593 |
ORF3a | 86 | L86F | ttG | ttT | 4 | 4 | AY.42 | 0.000161 |
ORF3a | 86 | L86F | ttG | ttT | 4 | 4 | B.1.234 | 0.000528 |
ORF3a | 86 | L86F | ttG | ttT | 3 | 4 | B.1.621 | 0.000266 |
ORF3a | 86 | L86F | ttG | ttT | 3 | 3 | AY.114 | 0.000693 |
ORF3a | 86 | L86F | ttG | ttT | 3 | 3 | AY.45 | 0.000365 |
ORF3a | 86 | L86F | ttG | ttT | 3 | 3 | B.1.1.10 | 0.003344 |
ORF3a | 86 | L86F | ttG | ttT | 3 | 3 | B.1.1.225 | 0.021583 |
ORF3a | 86 | L86F | ttG | ttT | 3 | 3 | B.1.1.519 | 0.000119 |
ORF3a | 86 | L86F | ttG | ttT | 3 | 3 | B.1.351.5 | 0.001799 |
ORF3a | 86 | L86F | ttG | ttT | 3 | 3 | B.1.36 | 0.000438 |
ORF3a | 86 | L86F | ttG | ttT | 3 | 3 | B.1.36.1 | 0.003421 |
ORF3a | 86 | L86F | ttG | ttT | 3 | 3 | B.1.524 | 0.004219 |
ORF3a | 86 | L86F | ttG | ttT | 3 | 3 | B.1.595 | 0.000783 |
ORF3a | 86 | L86F | ttG | ttT | 3 | 3 | B.1.617.1 | 0.000387 |
ORF3a | 86 | L86F | ttG | ttT | 3 | 3 | B.1.637 | 0.000219 |
ORF3a | 86 | L86F | ttG | ttT | 3 | 3 | B.40 | 0.001093 |
ORF3a | 86 | L86F | ttG | ttT | 3 | 3 | D.2 | 0.000225 |
ORF3a | 86 | L86F | ttG | ttT | 3 | 3 | P.1.12 | 0.001452 |
ORF3a | 86 | L86F | ttG | ttT | 3 | 3 | Z.1 | 0.008671 |
ORF3a | 86 | L86F | ttG | ttT | 2 | 2 | AY.118 | 0.000125 |
ORF3a | 86 | L86F | ttG | ttT | 2 | 2 | AY.12 | 0.000632 |
ORF3a | 86 | L86F | ttG | ttT | 2 | 2 | AY.120.1 | 0.000642 |
ORF3a | 86 | L86F | ttG | ttT | 2 | 2 | AY.39.1 | 0.000079 |
ORF3a | 86 | L86F | ttG | ttT | 2 | 2 | AY.46.6 | 0.000144 |
ORF3a | 86 | L86F | ttG | ttT | 2 | 2 | AY.55 | 0.001835 |
ORF3a | 86 | L86F | ttG | ttT | 2 | 2 | AY.72 | 0.002721 |
ORF3a | 86 | L86F | ttG | ttT | 2 | 2 | AY.78 | 0.003082 |
ORF3a | 86 | L86F | ttG | ttT | 2 | 2 | AY.9.2 | 0.000073 |
ORF3a | 86 | L86F | ttG | ttT | 2 | 2 | B.1.1.284 | 0.000215 |
ORF3a | 86 | L86F | ttG | ttT | 2 | 2 | B.1.1.291 | 0.001485 |
ORF3a | 86 | L86F | ttG | ttT | 2 | 2 | B.1.1.304 | 0.005618 |
ORF3a | 86 | L86F | ttG | ttT | 2 | 2 | B.1.1.335 | 0.025974 |
ORF3a | 86 | L86F | ttG | ttT | 2 | 2 | B.1.1.50 | 0.001358 |
ORF3a | 86 | L86F | ttG | ttT | 2 | 2 | B.1.1.99 | 0.047619 |
ORF3a | 86 | L86F | ttG | ttT | 2 | 2 | B.1.110.3 | 0.001437 |
ORF3a | 86 | L86F | ttG | ttT | 2 | 2 | B.1.221 | 0.000142 |
ORF3a | 86 | L86F | ttG | ttT | 2 | 2 | B.1.258 | 0.000133 |
ORF3a | 86 | L86F | ttG | ttT | 2 | 2 | B.1.311 | 0.000549 |
ORF3a | 86 | L86F | ttG | ttT | 2 | 2 | B.1.36.19 | 0.018519 |
ORF3a | 86 | L86F | ttG | ttT | 2 | 2 | B.1.395 | 0.014085 |
ORF3a | 86 | L86F | ttG | ttT | 2 | 2 | B.1.628 | 0.000705 |
ORF3a | 86 | L86F | ttG | ttT | 2 | 2 | C.1.2 | 0.008511 |
ORF3a | 86 | L86F | ttG | ttT | 2 | 2 | C.35 | 0.001548 |
ORF3a | 86 | L86F | ttG | ttT | 2 | 2 | Q.8 | 0.00033 |
ORF3a | 86 | L86F | ttG | ttT | 1 | 1 | 0.055556 | |
ORF3a | 86 | L86F | ttG | ttT | 1 | 1 | A.19 | 0.009434 |
ORF3a | 86 | L86F | ttG | ttT | 1 | 1 | A.21 | 0.00277 |
ORF3a | 86 | L86F | ttG | ttT | 1 | 1 | AY.10 | 0.00053 |
ORF3a | 86 | L86F | ttG | ttT | 1 | 1 | AY.105 | 0.000643 |
ORF3a | 86 | L86F | ttG | ttT | 1 | 1 | AY.106 | 0.000335 |
ORF3a | 86 | L86F | ttG | ttT | 1 | 1 | AY.108 | 0.001103 |
ORF3a | 86 | L86F | ttG | ttT | 1 | 1 | AY.109 | 0.00074 |
ORF3a | 86 | L86F | ttG | ttT | 1 | 1 | AY.116.1 | 0.000311 |
ORF3a | 86 | L86F | ttG | ttT | 1 | 1 | AY.14 | 0.000088 |
ORF3a | 86 | L86F | ttG | ttT | 1 | 1 | AY.15 | 0.002222 |
ORF3a | 86 | L86F | ttG | ttT | 1 | 1 | AY.16 | 0.00038 |
ORF3a | 86 | L86F | ttG | ttT | 1 | 1 | AY.27 | 0.000065 |
ORF3a | 86 | L86F | ttG | ttT | 1 | 1 | AY.34 | 0.000097 |
ORF3a | 86 | L86F | ttG | ttT | 1 | 1 | AY.37 | 0.000316 |
ORF3a | 86 | L86F | ttG | ttT | 1 | 1 | AY.4.2.1 | 0.000149 |
ORF3a | 86 | L86F | ttG | ttT | 1 | 1 | AY.4.5 | 0.000107 |
ORF3a | 86 | L86F | ttG | ttT | 1 | 1 | AY.46 | 0.000104 |
ORF3a | 86 | L86F | ttG | ttT | 1 | 1 | AY.46.4 | 0.000165 |
ORF3a | 86 | L86F | ttG | ttT | 1 | 1 | AY.46.5 | 0.000198 |
ORF3a | 86 | L86F | ttG | ttT | 1 | 1 | AY.5.1 | 0.003759 |
ORF3a | 86 | L86F | ttG | ttT | 1 | 1 | AY.57 | 0.000656 |
ORF3a | 86 | L86F | ttG | ttT | 1 | 1 | AY.7 | 0.000196 |
ORF3a | 86 | L86F | ttG | ttT | 1 | 1 | AY.71 | 0.000475 |
ORF3a | 86 | L86F | ttG | ttT | 1 | 1 | AY.75 | 0.000056 |
ORF3a | 86 | L86F | ttG | ttT | 1 | 1 | AY.77 | 0.001127 |
ORF3a | 86 | L86F | ttG | ttT | 1 | 1 | AY.79 | 0.001211 |
ORF3a | 86 | L86F | ttG | ttT | 1 | 1 | AY.84 | 0.000437 |
ORF3a | 86 | L86F | ttG | ttT | 1 | 1 | AY.85 | 0.000427 |
ORF3a | 86 | L86F | ttG | ttT | 1 | 1 | AY.88 | 0.000884 |
ORF3a | 86 | L86F | ttG | ttT | 1 | 1 | AY.9 | 0.000068 |
ORF3a | 86 | L86F | ttG | ttT | 1 | 1 | AY.92 | 0.000287 |
ORF3a | 86 | L86F | ttG | ttT | 1 | 1 | AY.99 | 0.001049 |
ORF3a | 86 | L86F | ttG | ttT | 1 | 1 | AY.99.2 | 0.000092 |
ORF3a | 86 | L86F | ttG | ttT | 1 | 1 | B | 0.000128 |
ORF3a | 86 | L86F | ttG | ttT | 1 | 1 | B.1.1.159 | 0.004673 |
ORF3a | 86 | L86F | ttG | ttT | 1 | 1 | B.1.1.216 | 0.00089 |
ORF3a | 86 | L86F | ttG | ttT | 1 | 1 | B.1.1.241 | 0.00207 |
ORF3a | 86 | L86F | ttG | ttT | 1 | 1 | B.1.1.261 | 0.008621 |
ORF3a | 86 | L86F | ttG | ttT | 1 | 1 | B.1.1.263 | 0.001558 |
ORF3a | 86 | L86F | ttG | ttT | 1 | 1 | B.1.1.316 | 0.000925 |
ORF3a | 86 | L86F | ttG | ttT | 1 | 1 | B.1.1.317 | 0.000412 |
ORF3a | 86 | L86F | ttG | ttT | 1 | 1 | B.1.1.318 | 0.000302 |
ORF3a | 86 | L86F | ttG | ttT | 1 | 1 | B.1.1.409 | 0.002833 |
ORF3a | 86 | L86F | ttG | ttT | 1 | 1 | B.1.1.416 | 0.000905 |
ORF3a | 86 | L86F | ttG | ttT | 1 | 1 | B.1.1.432 | 0.001266 |
ORF3a | 86 | L86F | ttG | ttT | 1 | 1 | B.1.1.449 | 0.022727 |
ORF3a | 86 | L86F | ttG | ttT | 1 | 1 | B.1.1.507 | 0.008696 |
ORF3a | 86 | L86F | ttG | ttT | 1 | 1 | B.1.1.8 | 0.003584 |
ORF3a | 86 | L86F | ttG | ttT | 1 | 1 | B.1.128 | 0.000635 |
ORF3a | 86 | L86F | ttG | ttT | 1 | 1 | B.1.169 | 0.014925 |
ORF3a | 86 | L86F | ttG | ttT | 1 | 1 | B.1.177.10 | 0.000878 |
ORF3a | 86 | L86F | ttG | ttT | 1 | 1 | B.1.177.11 | 0.001698 |
ORF3a | 86 | L86F | ttG | ttT | 1 | 1 | B.1.177.4 | 0.000211 |
ORF3a | 86 | L86F | ttG | ttT | 1 | 1 | B.1.177.53 | 0.002392 |
ORF3a | 86 | L86F | ttG | ttT | 1 | 1 | B.1.177.75 | 0.001041 |
ORF3a | 86 | L86F | ttG | ttT | 1 | 1 | B.1.177.81 | 0.000189 |
ORF3a | 86 | L86F | ttG | ttT | 1 | 1 | B.1.177.9 | 0.001332 |
ORF3a | 86 | L86F | ttG | ttT | 1 | 1 | B.1.239 | 0.001221 |
ORF3a | 86 | L86F | ttG | ttT | 1 | 1 | B.1.240 | 0.000216 |
ORF3a | 86 | L86F | ttG | ttT | 1 | 1 | B.1.241 | 0.000812 |
ORF3a | 86 | L86F | ttG | ttT | 1 | 1 | B.1.243 | 0.00007 |
ORF3a | 86 | L86F | ttG | ttT | 1 | 1 | B.1.258.17 | 0.000104 |
ORF3a | 86 | L86F | ttG | ttT | 1 | 1 | B.1.324 | 0.001605 |
ORF3a | 86 | L86F | ttG | ttT | 1 | 1 | B.1.36.31 | 0.001751 |
ORF3a | 86 | L86F | ttG | ttT | 1 | 1 | B.1.399 | 0.001934 |
ORF3a | 86 | L86F | ttG | ttT | 1 | 1 | B.1.407 | 0.035714 |
ORF3a | 86 | L86F | ttG | ttT | 1 | 1 | B.1.441 | 0.009615 |
ORF3a | 86 | L86F | ttG | ttT | 1 | 1 | B.1.470 | 0.001404 |
ORF3a | 86 | L86F | ttG | ttT | 1 | 1 | B.1.542 | 0.03125 |
ORF3a | 86 | L86F | ttG | ttT | 1 | 1 | B.1.576 | 0.000907 |
ORF3a | 86 | L86F | ttG | ttT | 1 | 1 | B.1.590 | 0.004545 |
ORF3a | 86 | L86F | ttG | ttT | 1 | 1 | B.1.596.1 | 0.009346 |
ORF3a | 86 | L86F | ttG | ttT | 1 | 1 | B.1.621.1 | 0.000506 |
ORF3a | 86 | L86F | ttG | ttT | 1 | 1 | C.13 | 0.025641 |
ORF3a | 86 | L86F | ttG | ttT | 1 | 1 | C.14 | 0.004329 |
ORF3a | 86 | L86F | ttG | ttT | 1 | 1 | N.3 | 0.005814 |
ORF3a | 86 | L86F | ttG | ttT | 1 | 1 | N.5 | 0.001767 |
ORF3a | 86 | L86F | ttG | ttT | 1 | 1 | N.9 | 0.005952 |
ORF3a | 86 | L86F | ttG | ttT | 1 | 1 | P.1.17 | 0.000162 |
ORF3a | 86 | L86F | ttG | ttT | 1 | 1 | R.1 | 0.00009 |
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CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk
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