CoV-GLUE | Mutations | Mutation
Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):
ORF | CodonNum | Mut | ORF1abMut | MutType | RefCodon | MutCodon | AACount | CodonCount | CodonProp | Genome Position |
ORF3a | 67 | K67N | nonsyn | aaG | aaT | 5269 | 3899 | 0.739989 | 25591-25593 |
Details of the mutation no within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):
ORF | CodonNum | Mut | RefCodon | MutCodon | CodonCount | AACount | Lineage | LineageCodonProp |
ORF3a | 67 | K67N | aaG | aaT | 3899 | 5269 | All | 0.000746 |
ORF3a | 67 | K67N | aaG | aaT | 1067 | 1102 | AY.4 | 0.001661 |
ORF3a | 67 | K67N | aaG | aaT | 677 | 1081 | B.1.1.7 | 0.000606 |
ORF3a | 67 | K67N | aaG | aaT | 104 | 299 | AY.3 | 0.001034 |
ORF3a | 67 | K67N | aaG | aaT | 204 | 233 | B.1.617.2 | 0.000768 |
ORF3a | 67 | K67N | aaG | aaT | 6 | 199 | P.1.14 | 0.000287 |
ORF3a | 67 | K67N | aaG | aaT | 143 | 167 | AY.103 | 0.000888 |
ORF3a | 67 | K67N | aaG | aaT | 146 | 152 | AY.43 | 0.000647 |
ORF3a | 67 | K67N | aaG | aaT | 107 | 138 | B.1.2 | 0.000942 |
ORF3a | 67 | K67N | aaG | aaT | 127 | 127 | AY.116.1 | 0.039552 |
ORF3a | 67 | K67N | aaG | aaT | 117 | 118 | AY.9.2 | 0.004297 |
ORF3a | 67 | K67N | aaG | aaT | 41 | 103 | B.1 | 0.000376 |
ORF3a | 67 | K67N | aaG | aaT | 76 | 100 | AY.44 | 0.000463 |
ORF3a | 67 | K67N | aaG | aaT | 11 | 77 | AY.26 | 0.000311 |
ORF3a | 67 | K67N | aaG | aaT | 73 | 77 | AY.47 | 0.002271 |
ORF3a | 67 | K67N | aaG | aaT | 61 | 61 | B.1.258.20 | 0.968254 |
ORF3a | 67 | K67N | aaG | aaT | 39 | 41 | P.1 | 0.000614 |
ORF3a | 67 | K67N | aaG | aaT | 11 | 40 | AY.39 | 0.000272 |
ORF3a | 67 | K67N | aaG | aaT | 36 | 39 | B.1.1 | 0.000653 |
ORF3a | 67 | K67N | aaG | aaT | 37 | 37 | AY.4.2 | 0.000802 |
ORF3a | 67 | K67N | aaG | aaT | 27 | 37 | B.1.351 | 0.000803 |
ORF3a | 67 | K67N | aaG | aaT | 23 | 35 | AY.25 | 0.000138 |
ORF3a | 67 | K67N | aaG | aaT | 35 | 35 | B.1.160 | 0.001092 |
ORF3a | 67 | K67N | aaG | aaT | 23 | 32 | AY.102 | 0.00061 |
ORF3a | 67 | K67N | aaG | aaT | 21 | 31 | B.1.526 | 0.000494 |
ORF3a | 67 | K67N | aaG | aaT | 18 | 30 | B.1.429 | 0.000424 |
ORF3a | 67 | K67N | aaG | aaT | 11 | 28 | B.1.177 | 0.000145 |
ORF3a | 67 | K67N | aaG | aaT | 13 | 25 | B.1.1.519 | 0.000516 |
ORF3a | 67 | K67N | aaG | aaT | 23 | 24 | AY.120 | 0.000855 |
ORF3a | 67 | K67N | aaG | aaT | 11 | 21 | AY.39.1 | 0.000436 |
ORF3a | 67 | K67N | aaG | aaT | 21 | 21 | B.1.177.77 | 0.015251 |
ORF3a | 67 | K67N | aaG | aaT | 19 | 19 | B.1.366 | 0.092683 |
ORF3a | 67 | K67N | aaG | aaT | 17 | 18 | AY.5 | 0.000351 |
ORF3a | 67 | K67N | aaG | aaT | 8 | 17 | B.1.595 | 0.002088 |
ORF3a | 67 | K67N | aaG | aaT | 5 | 16 | AY.33 | 0.000334 |
ORF3a | 67 | K67N | aaG | aaT | 15 | 15 | AY.93 | 0.004096 |
ORF3a | 67 | K67N | aaG | aaT | 15 | 15 | B.1.630 | 0.078534 |
ORF3a | 67 | K67N | aaG | aaT | 11 | 13 | AY.23 | 0.000767 |
ORF3a | 67 | K67N | aaG | aaT | 12 | 13 | AY.34 | 0.001164 |
ORF3a | 67 | K67N | aaG | aaT | 13 | 13 | B.1.400 | 0.005577 |
ORF3a | 67 | K67N | aaG | aaT | 13 | 13 | Q.8 | 0.002144 |
ORF3a | 67 | K67N | aaG | aaT | 12 | 12 | A.2.5 | 0.005988 |
ORF3a | 67 | K67N | aaG | aaT | 5 | 12 | AY.100 | 0.00023 |
ORF3a | 67 | K67N | aaG | aaT | 9 | 12 | AY.20 | 0.00035 |
ORF3a | 67 | K67N | aaG | aaT | 10 | 12 | AY.45 | 0.001217 |
ORF3a | 67 | K67N | aaG | aaT | 1 | 12 | B.1.1.1 | 0.000327 |
ORF3a | 67 | K67N | aaG | aaT | 9 | 12 | B.1.1.214 | 0.000499 |
ORF3a | 67 | K67N | aaG | aaT | 11 | 12 | C.37 | 0.001277 |
ORF3a | 67 | K67N | aaG | aaT | 11 | 11 | AY.3.1 | 0.000938 |
ORF3a | 67 | K67N | aaG | aaT | 11 | 11 | B.1.1.37 | 0.002122 |
ORF3a | 67 | K67N | aaG | aaT | 10 | 10 | AY.98.1 | 0.000484 |
ORF3a | 67 | K67N | aaG | aaT | 10 | 10 | B.1.36.19 | 0.092593 |
ORF3a | 67 | K67N | aaG | aaT | 9 | 10 | B.1.427 | 0.000454 |
ORF3a | 67 | K67N | aaG | aaT | 9 | 9 | B.1.214.3 | 0.064286 |
ORF3a | 67 | K67N | aaG | aaT | 3 | 9 | B.1.36 | 0.000438 |
ORF3a | 67 | K67N | aaG | aaT | 9 | 9 | B.1.596 | 0.000784 |
ORF3a | 67 | K67N | aaG | aaT | 7 | 8 | AY.42 | 0.000282 |
ORF3a | 67 | K67N | aaG | aaT | 6 | 8 | AY.46 | 0.000624 |
ORF3a | 67 | K67N | aaG | aaT | 8 | 8 | B.1.177.84 | 0.053333 |
ORF3a | 67 | K67N | aaG | aaT | 7 | 7 | AY.121 | 0.000947 |
ORF3a | 67 | K67N | aaG | aaT | 6 | 7 | AY.98 | 0.000474 |
ORF3a | 67 | K67N | aaG | aaT | 7 | 7 | B.1.177.88 | 0.08642 |
ORF3a | 67 | K67N | aaG | aaT | 7 | 7 | B.1.241 | 0.005682 |
ORF3a | 67 | K67N | aaG | aaT | 7 | 7 | B.1.369 | 0.001997 |
ORF3a | 67 | K67N | aaG | aaT | 7 | 7 | B.1.471 | 0.019126 |
ORF3a | 67 | K67N | aaG | aaT | 7 | 7 | R.1 | 0.00063 |
ORF3a | 67 | K67N | aaG | aaT | 4 | 6 | AY.119 | 0.000141 |
ORF3a | 67 | K67N | aaG | aaT | 5 | 6 | AY.75 | 0.00028 |
ORF3a | 67 | K67N | aaG | aaT | 6 | 6 | AY.99.2 | 0.000553 |
ORF3a | 67 | K67N | aaG | aaT | 6 | 6 | B.1.240 | 0.001293 |
ORF3a | 67 | K67N | aaG | aaT | 6 | 6 | B.1.258 | 0.000399 |
ORF3a | 67 | K67N | aaG | aaT | 6 | 6 | B.1.258.17 | 0.000624 |
ORF3a | 67 | K67N | aaG | aaT | 6 | 6 | B.1.398 | 0.017857 |
ORF3a | 67 | K67N | aaG | aaT | 2 | 6 | B.1.621 | 0.000177 |
ORF3a | 67 | K67N | aaG | aaT | 5 | 5 | AY.116 | 0.001434 |
ORF3a | 67 | K67N | aaG | aaT | 5 | 5 | AY.120.2 | 0.006427 |
ORF3a | 67 | K67N | aaG | aaT | 3 | 5 | B.1.221 | 0.000213 |
ORF3a | 67 | K67N | aaG | aaT | 5 | 5 | B.1.36.8 | 0.005 |
ORF3a | 67 | K67N | aaG | aaT | 5 | 5 | B.1.438.1 | 0.000536 |
ORF3a | 67 | K67N | aaG | aaT | 3 | 4 | 0.166667 | |
ORF3a | 67 | K67N | aaG | aaT | 3 | 4 | A | 0.001161 |
ORF3a | 67 | K67N | aaG | aaT | 2 | 4 | AY.117 | 0.000169 |
ORF3a | 67 | K67N | aaG | aaT | 3 | 4 | AY.29 | 0.000047 |
ORF3a | 67 | K67N | aaG | aaT | 4 | 4 | AY.41 | 0.001176 |
ORF3a | 67 | K67N | aaG | aaT | 1 | 4 | AY.61 | 0.000105 |
ORF3a | 67 | K67N | aaG | aaT | 4 | 4 | AY.9 | 0.00027 |
ORF3a | 67 | K67N | aaG | aaT | 3 | 4 | B.1.1.222 | 0.000612 |
ORF3a | 67 | K67N | aaG | aaT | 4 | 4 | B.1.1.244 | 0.061538 |
ORF3a | 67 | K67N | aaG | aaT | 4 | 4 | B.1.1.25 | 0.002274 |
ORF3a | 67 | K67N | aaG | aaT | 4 | 4 | B.1.1.528 | 0.019231 |
ORF3a | 67 | K67N | aaG | aaT | 4 | 4 | B.1.243 | 0.000278 |
ORF3a | 67 | K67N | aaG | aaT | 4 | 4 | B.1.270 | 0.022472 |
ORF3a | 67 | K67N | aaG | aaT | 4 | 4 | C.36.3 | 0.002269 |
ORF3a | 67 | K67N | aaG | aaT | 2 | 3 | AY.113 | 0.000285 |
ORF3a | 67 | K67N | aaG | aaT | 3 | 3 | AY.19 | 0.003421 |
ORF3a | 67 | K67N | aaG | aaT | 3 | 3 | AY.71 | 0.001425 |
ORF3a | 67 | K67N | aaG | aaT | 3 | 3 | AY.9.1 | 0.000251 |
ORF3a | 67 | K67N | aaG | aaT | 1 | 3 | B.1.1.216 | 0.00089 |
ORF3a | 67 | K67N | aaG | aaT | 3 | 3 | B.1.1.486 | 0.004732 |
ORF3a | 67 | K67N | aaG | aaT | 3 | 3 | B.1.1.51 | 0.005155 |
ORF3a | 67 | K67N | aaG | aaT | 3 | 3 | B.1.362 | 0.004622 |
ORF3a | 67 | K67N | aaG | aaT | 2 | 3 | B.1.466.2 | 0.000782 |
ORF3a | 67 | K67N | aaG | aaT | 3 | 3 | B.1.617.1 | 0.000387 |
ORF3a | 67 | K67N | aaG | aaT | 2 | 3 | B.1.637 | 0.000146 |
ORF3a | 67 | K67N | aaG | aaT | 1 | 3 | N.4 | 0.004255 |
ORF3a | 67 | K67N | aaG | aaT | 1 | 3 | P.1.2 | 0.001156 |
ORF3a | 67 | K67N | aaG | aaT | 1 | 2 | AD.2 | 0.000219 |
ORF3a | 67 | K67N | aaG | aaT | 2 | 2 | AY.106 | 0.00067 |
ORF3a | 67 | K67N | aaG | aaT | 2 | 2 | AY.109 | 0.001479 |
ORF3a | 67 | K67N | aaG | aaT | 1 | 2 | AY.118 | 0.000063 |
ORF3a | 67 | K67N | aaG | aaT | 2 | 2 | AY.13 | 0.000322 |
ORF3a | 67 | K67N | aaG | aaT | 2 | 2 | AY.32 | 0.001065 |
ORF3a | 67 | K67N | aaG | aaT | 2 | 2 | AY.46.6 | 0.000144 |
ORF3a | 67 | K67N | aaG | aaT | 2 | 2 | AY.53 | 0.000575 |
ORF3a | 67 | K67N | aaG | aaT | 2 | 2 | AY.54 | 0.000191 |
ORF3a | 67 | K67N | aaG | aaT | 1 | 2 | AY.56 | 0.001605 |
ORF3a | 67 | K67N | aaG | aaT | 2 | 2 | B.1.1.229 | 0.011494 |
ORF3a | 67 | K67N | aaG | aaT | 2 | 2 | B.1.1.294 | 0.002532 |
ORF3a | 67 | K67N | aaG | aaT | 2 | 2 | B.1.1.328 | 0.033898 |
ORF3a | 67 | K67N | aaG | aaT | 1 | 2 | B.1.1.33 | 0.000421 |
ORF3a | 67 | K67N | aaG | aaT | 2 | 2 | B.1.1.348 | 0.001592 |
ORF3a | 67 | K67N | aaG | aaT | 2 | 2 | B.1.1.354 | 0.008772 |
ORF3a | 67 | K67N | aaG | aaT | 2 | 2 | B.1.1.368 | 0.006173 |
ORF3a | 67 | K67N | aaG | aaT | 2 | 2 | B.1.145 | 0.105263 |
ORF3a | 67 | K67N | aaG | aaT | 2 | 2 | B.1.177.21 | 0.000153 |
ORF3a | 67 | K67N | aaG | aaT | 2 | 2 | B.1.214 | 0.007326 |
ORF3a | 67 | K67N | aaG | aaT | 2 | 2 | B.1.234 | 0.000264 |
ORF3a | 67 | K67N | aaG | aaT | 1 | 2 | B.1.239 | 0.001221 |
ORF3a | 67 | K67N | aaG | aaT | 2 | 2 | B.1.258.12 | 0.015748 |
ORF3a | 67 | K67N | aaG | aaT | 1 | 2 | B.1.311 | 0.000275 |
ORF3a | 67 | K67N | aaG | aaT | 1 | 2 | B.1.36.17 | 0.000494 |
ORF3a | 67 | K67N | aaG | aaT | 2 | 2 | B.1.36.29 | 0.001035 |
ORF3a | 67 | K67N | aaG | aaT | 2 | 2 | B.1.480 | 0.004975 |
ORF3a | 67 | K67N | aaG | aaT | 2 | 2 | B.1.499 | 0.002101 |
ORF3a | 67 | K67N | aaG | aaT | 2 | 2 | B.1.525 | 0.000226 |
ORF3a | 67 | K67N | aaG | aaT | 2 | 2 | B.1.540 | 0.019417 |
ORF3a | 67 | K67N | aaG | aaT | 2 | 2 | B.1.609 | 0.000959 |
ORF3a | 67 | K67N | aaG | aaT | 2 | 2 | D.2 | 0.00015 |
ORF3a | 67 | K67N | aaG | aaT | 2 | 2 | P.1.1 | 0.000635 |
ORF3a | 67 | K67N | aaG | aaT | 2 | 2 | P.2 | 0.000373 |
ORF3a | 67 | K67N | aaG | aaT | 1 | 1 | A.1 | 0.000282 |
ORF3a | 67 | K67N | aaG | aaT | 1 | 1 | A.19 | 0.009434 |
ORF3a | 67 | K67N | aaG | aaT | 1 | 1 | A.2.5.2 | 0.001572 |
ORF3a | 67 | K67N | aaG | aaT | 1 | 1 | AY.105 | 0.000643 |
ORF3a | 67 | K67N | aaG | aaT | 1 | 1 | AY.115 | 0.005208 |
ORF3a | 67 | K67N | aaG | aaT | 1 | 1 | AY.14 | 0.000088 |
ORF3a | 67 | K67N | aaG | aaT | 1 | 1 | AY.24 | 0.000431 |
ORF3a | 67 | K67N | aaG | aaT | 1 | 1 | AY.35 | 0.000233 |
ORF3a | 67 | K67N | aaG | aaT | 1 | 1 | AY.38 | 0.000499 |
ORF3a | 67 | K67N | aaG | aaT | 1 | 1 | AY.4.5 | 0.000107 |
ORF3a | 67 | K67N | aaG | aaT | 1 | 1 | AY.40 | 0.000964 |
ORF3a | 67 | K67N | aaG | aaT | 1 | 1 | AY.48 | 0.000465 |
ORF3a | 67 | K67N | aaG | aaT | 1 | 1 | AY.5.4 | 0.000277 |
ORF3a | 67 | K67N | aaG | aaT | 1 | 1 | AY.58 | 0.000907 |
ORF3a | 67 | K67N | aaG | aaT | 1 | 1 | AY.59 | 0.00053 |
ORF3a | 67 | K67N | aaG | aaT | 1 | 1 | AY.7 | 0.000196 |
ORF3a | 67 | K67N | aaG | aaT | 1 | 1 | AY.73 | 0.000665 |
ORF3a | 67 | K67N | aaG | aaT | 1 | 1 | AY.76 | 0.004831 |
ORF3a | 67 | K67N | aaG | aaT | 1 | 1 | AY.77 | 0.001127 |
ORF3a | 67 | K67N | aaG | aaT | 1 | 1 | AY.79 | 0.001211 |
ORF3a | 67 | K67N | aaG | aaT | 1 | 1 | AY.86 | 0.00083 |
ORF3a | 67 | K67N | aaG | aaT | 1 | 1 | AY.90 | 0.000684 |
ORF3a | 67 | K67N | aaG | aaT | 1 | 1 | AY.95 | 0.000761 |
ORF3a | 67 | K67N | aaG | aaT | 1 | 1 | AY.96 | 0.002075 |
ORF3a | 67 | K67N | aaG | aaT | 1 | 1 | AY.97 | 0.001701 |
ORF3a | 67 | K67N | aaG | aaT | 1 | 1 | B.1.1.218 | 0.007692 |
ORF3a | 67 | K67N | aaG | aaT | 1 | 1 | B.1.1.226 | 0.005814 |
ORF3a | 67 | K67N | aaG | aaT | 1 | 1 | B.1.1.284 | 0.000107 |
ORF3a | 67 | K67N | aaG | aaT | 1 | 1 | B.1.1.297 | 0.002237 |
ORF3a | 67 | K67N | aaG | aaT | 1 | 1 | B.1.1.304 | 0.002809 |
ORF3a | 67 | K67N | aaG | aaT | 1 | 1 | B.1.1.306 | 0.000438 |
ORF3a | 67 | K67N | aaG | aaT | 1 | 1 | B.1.1.318 | 0.000302 |
ORF3a | 67 | K67N | aaG | aaT | 1 | 1 | B.1.1.374 | 0.002375 |
ORF3a | 67 | K67N | aaG | aaT | 1 | 1 | B.1.1.432 | 0.001266 |
ORF3a | 67 | K67N | aaG | aaT | 1 | 1 | B.1.1.442 | 0.018519 |
ORF3a | 67 | K67N | aaG | aaT | 1 | 1 | B.1.1.448 | 0.002033 |
ORF3a | 67 | K67N | aaG | aaT | 1 | 1 | B.1.1.48 | 0.002874 |
ORF3a | 67 | K67N | aaG | aaT | 1 | 1 | B.1.1.526 | 0.003546 |
ORF3a | 67 | K67N | aaG | aaT | 1 | 1 | B.1.1.89 | 0.006061 |
ORF3a | 67 | K67N | aaG | aaT | 1 | 1 | B.1.177.73 | 0.000566 |
ORF3a | 67 | K67N | aaG | aaT | 1 | 1 | B.1.177.81 | 0.000189 |
ORF3a | 67 | K67N | aaG | aaT | 1 | 1 | B.1.177.85 | 0.005435 |
ORF3a | 67 | K67N | aaG | aaT | 1 | 1 | B.1.177.86 | 0.000183 |
ORF3a | 67 | K67N | aaG | aaT | 1 | 1 | B.1.192 | 0.009259 |
ORF3a | 67 | K67N | aaG | aaT | 1 | 1 | B.1.223 | 0.002778 |
ORF3a | 67 | K67N | aaG | aaT | 1 | 1 | B.1.258.7 | 0.001912 |
ORF3a | 67 | K67N | aaG | aaT | 1 | 1 | B.1.284 | 0.013158 |
ORF3a | 67 | K67N | aaG | aaT | 1 | 1 | B.1.326 | 0.007576 |
ORF3a | 67 | K67N | aaG | aaT | 1 | 1 | B.1.36.1 | 0.00114 |
ORF3a | 67 | K67N | aaG | aaT | 1 | 1 | B.1.381 | 0.007812 |
ORF3a | 67 | K67N | aaG | aaT | 1 | 1 | B.1.396 | 0.000706 |
ORF3a | 67 | K67N | aaG | aaT | 1 | 1 | B.1.428 | 0.00102 |
ORF3a | 67 | K67N | aaG | aaT | 1 | 1 | B.1.456 | 0.003268 |
ORF3a | 67 | K67N | aaG | aaT | 1 | 1 | B.1.542 | 0.03125 |
ORF3a | 67 | K67N | aaG | aaT | 1 | 1 | B.1.565 | 0.00081 |
ORF3a | 67 | K67N | aaG | aaT | 1 | 1 | B.1.575 | 0.000303 |
ORF3a | 67 | K67N | aaG | aaT | 1 | 1 | B.1.576 | 0.000907 |
ORF3a | 67 | K67N | aaG | aaT | 1 | 1 | B.1.588 | 0.00091 |
ORF3a | 67 | K67N | aaG | aaT | 1 | 1 | B.1.612 | 0.002653 |
ORF3a | 67 | K67N | aaG | aaT | 1 | 1 | B.1.623 | 0.000536 |
ORF3a | 67 | K67N | aaG | aaT | 1 | 1 | B.1.9.4 | 0.006135 |
ORF3a | 67 | K67N | aaG | aaT | 1 | 1 | B.1.93 | 0.000934 |
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CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk
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