CoV-GLUE Mutation

CoV-GLUE Mutation: ORF = ORF3a : CodonNum = 67 & Codon = aaC

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORF	CodonNum	Mut	ORF1abMut	MutType	RefCodon	MutCodon	AACount	CodonCount	CodonProp	Genome Position
ORF3a	67	K67N		nonsyn	aaG	aaC	5269	1370	0.260011	25591-25593

Details of the mutation no within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORF	CodonNum	Mut	RefCodon	MutCodon	CodonCount	AACount	Lineage	LineageCodonProp
ORF3a	67	K67N	aaG	aaC	1370	5269	All	0.000262
ORF3a	67	K67N	aaG	aaC	35	1102	AY.4	0.000054
ORF3a	67	K67N	aaG	aaC	404	1081	B.1.1.7	0.000362
ORF3a	67	K67N	aaG	aaC	195	299	AY.3	0.00194
ORF3a	67	K67N	aaG	aaC	29	233	B.1.617.2	0.000109
ORF3a	67	K67N	aaG	aaC	193	199	P.1.14	0.009226
ORF3a	67	K67N	aaG	aaC	24	167	AY.103	0.000149
ORF3a	67	K67N	aaG	aaC	6	152	AY.43	0.000027
ORF3a	67	K67N	aaG	aaC	31	138	B.1.2	0.000273
ORF3a	67	K67N	aaG	aaC	1	118	AY.9.2	0.000037
ORF3a	67	K67N	aaG	aaC	62	103	B.1	0.000568
ORF3a	67	K67N	aaG	aaC	24	100	AY.44	0.000146
ORF3a	67	K67N	aaG	aaC	66	77	AY.26	0.001868
ORF3a	67	K67N	aaG	aaC	4	77	AY.47	0.000124
ORF3a	67	K67N	aaG	aaC	2	41	P.1	0.000032
ORF3a	67	K67N	aaG	aaC	29	40	AY.39	0.000717
ORF3a	67	K67N	aaG	aaC	3	39	B.1.1	0.000054
ORF3a	67	K67N	aaG	aaC	10	37	B.1.351	0.000297
ORF3a	67	K67N	aaG	aaC	12	35	AY.25	0.000072
ORF3a	67	K67N	aaG	aaC	9	32	AY.102	0.000239
ORF3a	67	K67N	aaG	aaC	10	31	B.1.526	0.000235
ORF3a	67	K67N	aaG	aaC	12	30	B.1.429	0.000282
ORF3a	67	K67N	aaG	aaC	17	28	B.1.177	0.000224
ORF3a	67	K67N	aaG	aaC	28	28	B.3	0.023256
ORF3a	67	K67N	aaG	aaC	12	25	B.1.1.519	0.000477
ORF3a	67	K67N	aaG	aaC	1	24	AY.120	0.000037
ORF3a	67	K67N	aaG	aaC	10	21	AY.39.1	0.000396
ORF3a	67	K67N	aaG	aaC	1	18	AY.5	0.000021
ORF3a	67	K67N	aaG	aaC	9	17	B.1.595	0.002349
ORF3a	67	K67N	aaG	aaC	11	16	AY.33	0.000735
ORF3a	67	K67N	aaG	aaC	2	13	AY.23	0.000139
ORF3a	67	K67N	aaG	aaC	1	13	AY.34	0.000097
ORF3a	67	K67N	aaG	aaC	7	12	AY.100	0.000322
ORF3a	67	K67N	aaG	aaC	3	12	AY.20	0.000117
ORF3a	67	K67N	aaG	aaC	2	12	AY.45	0.000243
ORF3a	67	K67N	aaG	aaC	11	12	B.1.1.1	0.003594
ORF3a	67	K67N	aaG	aaC	3	12	B.1.1.214	0.000166
ORF3a	67	K67N	aaG	aaC	1	12	C.37	0.000116
ORF3a	67	K67N	aaG	aaC	1	10	B.1.427	0.00005
ORF3a	67	K67N	aaG	aaC	6	9	B.1.36	0.000875
ORF3a	67	K67N	aaG	aaC	1	8	AY.42	0.00004
ORF3a	67	K67N	aaG	aaC	2	8	AY.46	0.000208
ORF3a	67	K67N	aaG	aaC	1	7	AY.98	0.000079
ORF3a	67	K67N	aaG	aaC	2	6	AY.119	0.000071
ORF3a	67	K67N	aaG	aaC	1	6	AY.75	0.000056
ORF3a	67	K67N	aaG	aaC	4	6	B.1.621	0.000354
ORF3a	67	K67N	aaG	aaC	5	5	AY.57	0.003281
ORF3a	67	K67N	aaG	aaC	2	5	B.1.221	0.000142
ORF3a	67	K67N	aaG	aaC	1	4		0.055556
ORF3a	67	K67N	aaG	aaC	1	4	A	0.000387
ORF3a	67	K67N	aaG	aaC	2	4	AY.117	0.000169
ORF3a	67	K67N	aaG	aaC	1	4	AY.29	0.000016
ORF3a	67	K67N	aaG	aaC	3	4	AY.61	0.000314
ORF3a	67	K67N	aaG	aaC	1	4	B.1.1.222	0.000204
ORF3a	67	K67N	aaG	aaC	4	4	B.1.1.63	0.001543
ORF3a	67	K67N	aaG	aaC	4	4	B.1.320	0.004981
ORF3a	67	K67N	aaG	aaC	3	3	AY.107	0.001398
ORF3a	67	K67N	aaG	aaC	1	3	AY.113	0.000142
ORF3a	67	K67N	aaG	aaC	2	3	B.1.1.216	0.001781
ORF3a	67	K67N	aaG	aaC	1	3	B.1.466.2	0.000391
ORF3a	67	K67N	aaG	aaC	1	3	B.1.637	0.000073
ORF3a	67	K67N	aaG	aaC	2	3	N.4	0.008511
ORF3a	67	K67N	aaG	aaC	2	3	P.1.2	0.002312
ORF3a	67	K67N	aaG	aaC	1	2	AD.2	0.000219
ORF3a	67	K67N	aaG	aaC	1	2	AY.118	0.000063
ORF3a	67	K67N	aaG	aaC	1	2	AY.56	0.001605
ORF3a	67	K67N	aaG	aaC	2	2	B.1.1.159	0.009346
ORF3a	67	K67N	aaG	aaC	1	2	B.1.1.33	0.000421
ORF3a	67	K67N	aaG	aaC	1	2	B.1.239	0.001221
ORF3a	67	K67N	aaG	aaC	1	2	B.1.311	0.000275
ORF3a	67	K67N	aaG	aaC	1	2	B.1.36.17	0.000494
ORF3a	67	K67N	aaG	aaC	2	2	B.1.409	0.001563
ORF3a	67	K67N	aaG	aaC	2	2	B.1.638	0.105263
ORF3a	67	K67N	aaG	aaC	1	1	AY.34.1	0.00051
ORF3a	67	K67N	aaG	aaC	1	1	AY.36	0.000148
ORF3a	67	K67N	aaG	aaC	1	1	AY.68	0.000274
ORF3a	67	K67N	aaG	aaC	1	1	AY.75.1	0.00018
ORF3a	67	K67N	aaG	aaC	1	1	AY.91	0.00073
ORF3a	67	K67N	aaG	aaC	1	1	B.1.1.133	0.008475
ORF3a	67	K67N	aaG	aaC	1	1	B.1.1.141	0.002012
ORF3a	67	K67N	aaG	aaC	1	1	B.1.1.28	0.000311
ORF3a	67	K67N	aaG	aaC	1	1	B.1.1.311	0.000358
ORF3a	67	K67N	aaG	aaC	1	1	B.1.1.409	0.002833
ORF3a	67	K67N	aaG	aaC	1	1	B.1.36.18	0.00042
ORF3a	67	K67N	aaG	aaC	1	1	B.1.382	0.008929
ORF3a	67	K67N	aaG	aaC	1	1	B.1.397	0.004854
ORF3a	67	K67N	aaG	aaC	1	1	B.1.416.1	0.001563
ORF3a	67	K67N	aaG	aaC	1	1	B.1.434	0.052632
ORF3a	67	K67N	aaG	aaC	1	1	B.1.459	0.004082
ORF3a	67	K67N	aaG	aaC	1	1	B.1.504	0.03125
ORF3a	67	K67N	aaG	aaC	1	1	B.1.564.1	0.001577
ORF3a	67	K67N	aaG	aaC	1	1	B.40	0.000364
ORF3a	67	K67N	aaG	aaC	1	1	B.55	0.00295
ORF3a	67	K67N	aaG	aaC	1	1	K.2	0.04
ORF3a	67	K67N	aaG	aaC	1	1	P.1.12	0.000484
ORF3a	67	K67N	aaG	aaC	1	1	Q.5	0.016949

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.