CoV-GLUE Mutation

CoV-GLUE Mutation: ORF = ORF3a : CodonNum = 34 & Codon = acC

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORF	CodonNum	Mut	ORF1abMut	MutType	RefCodon	MutCodon	AACount	CodonCount	CodonProp	Genome Position
ORF3a	34	T34T		syn	acG	acC	11062	269	0.0243175	25492-25494

Details of the mutation no within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORF	CodonNum	Mut	RefCodon	MutCodon	CodonCount	AACount	Lineage	LineageCodonProp
ORF3a	34	T34T	acG	acC	269	11062	All	0.000051
ORF3a	34	T34T	acG	acC	40	1443	B.1.1.7	0.000036
ORF3a	34	T34T	acG	acC	16	1272	AY.4	0.000025
ORF3a	34	T34T	acG	acC	20	1079	B.1.617.2	0.000075
ORF3a	34	T34T	acG	acC	1	698	B.1.36.16	0.001425
ORF3a	34	T34T	acG	acC	2	440	AY.43	0.000009
ORF3a	34	T34T	acG	acC	4	248	AY.44	0.000024
ORF3a	34	T34T	acG	acC	5	237	B.1	0.000046
ORF3a	34	T34T	acG	acC	3	133	AY.102	0.00008
ORF3a	34	T34T	acG	acC	2	130	B.1.2	0.000018
ORF3a	34	T34T	acG	acC	3	121	AY.3	0.00003
ORF3a	34	T34T	acG	acC	6	100	AY.103	0.000037
ORF3a	34	T34T	acG	acC	14	95	P.1	0.000221
ORF3a	34	T34T	acG	acC	1	77	B.1.177	0.000013
ORF3a	34	T34T	acG	acC	3	60	B.1.1	0.000054
ORF3a	34	T34T	acG	acC	56	56	AY.4.5	0.00602
ORF3a	34	T34T	acG	acC	1	53	AY.39	0.000025
ORF3a	34	T34T	acG	acC	45	45	B.1.351.3	0.039439
ORF3a	34	T34T	acG	acC	1	44	AY.26	0.000028
ORF3a	34	T34T	acG	acC	1	35	B.1.429	0.000024
ORF3a	34	T34T	acG	acC	1	33	AY.117	0.000085
ORF3a	34	T34T	acG	acC	1	32	AY.75	0.000056
ORF3a	34	T34T	acG	acC	2	31	AY.113	0.000285
ORF3a	34	T34T	acG	acC	1	31	B.1.160	0.000031
ORF3a	34	T34T	acG	acC	1	30	B.1.596	0.000087
ORF3a	34	T34T	acG	acC	4	22	B.1.36	0.000584
ORF3a	34	T34T	acG	acC	4	20	AY.100	0.000184
ORF3a	34	T34T	acG	acC	2	20	B.1.1.222	0.000408
ORF3a	34	T34T	acG	acC	1	17	B.1.351	0.00003
ORF3a	34	T34T	acG	acC	1	14	AY.98	0.000079
ORF3a	34	T34T	acG	acC	1	13	AY.119	0.000035
ORF3a	34	T34T	acG	acC	13	13	B.1.1.169	0.236364
ORF3a	34	T34T	acG	acC	1	8	AY.23	0.00007
ORF3a	34	T34T	acG	acC	1	7	AY.99.2	0.000092
ORF3a	34	T34T	acG	acC	1	7	B.1.1.216	0.00089
ORF3a	34	T34T	acG	acC	1	6	AY.30	0.000396
ORF3a	34	T34T	acG	acC	2	3	AY.91	0.001461
ORF3a	34	T34T	acG	acC	2	3	B.1.258.17	0.000208
ORF3a	34	T34T	acG	acC	3	3	B.1.36.38	0.004926
ORF3a	34	T34T	acG	acC	1	1	B.1.234	0.000132
ORF3a	34	T34T	acG	acC	1	1	B.1.565	0.00081

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.