CoV-GLUE Mutation

CoV-GLUE Mutation: ORF = ORF3a : CodonNum = 34 & Codon = acA

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORF	CodonNum	Mut	ORF1abMut	MutType	RefCodon	MutCodon	AACount	CodonCount	CodonProp	Genome Position
ORF3a	34	T34T		syn	acG	acA	11062	1127	0.10188	25492-25494

Details of the mutation no within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORF	CodonNum	Mut	RefCodon	MutCodon	CodonCount	AACount	Lineage	LineageCodonProp
ORF3a	34	T34T	acG	acA	1127	11062	All	0.000216
ORF3a	34	T34T	acG	acA	193	1443	B.1.1.7	0.000173
ORF3a	34	T34T	acG	acA	1	1380	B.1.258	0.000067
ORF3a	34	T34T	acG	acA	208	1272	AY.4	0.000324
ORF3a	34	T34T	acG	acA	75	1079	B.1.617.2	0.000282
ORF3a	34	T34T	acG	acA	29	440	AY.43	0.000128
ORF3a	34	T34T	acG	acA	1	257	AY.13	0.000161
ORF3a	34	T34T	acG	acA	56	248	AY.44	0.000341
ORF3a	34	T34T	acG	acA	30	237	B.1	0.000275
ORF3a	34	T34T	acG	acA	9	180	AY.25	0.000054
ORF3a	34	T34T	acG	acA	16	133	AY.102	0.000424
ORF3a	34	T34T	acG	acA	36	130	B.1.2	0.000317
ORF3a	34	T34T	acG	acA	68	121	AY.3	0.000676
ORF3a	34	T34T	acG	acA	18	100	AY.103	0.000112
ORF3a	34	T34T	acG	acA	15	95	P.1	0.000236
ORF3a	34	T34T	acG	acA	5	77	B.1.177	0.000066
ORF3a	34	T34T	acG	acA	16	67	AY.5	0.00033
ORF3a	34	T34T	acG	acA	6	60	B.1.1	0.000109
ORF3a	34	T34T	acG	acA	7	60	B.1.1.519	0.000278
ORF3a	34	T34T	acG	acA	1	58	AY.46	0.000104
ORF3a	34	T34T	acG	acA	52	57	Q.1	0.006569
ORF3a	34	T34T	acG	acA	9	53	AY.39	0.000222
ORF3a	34	T34T	acG	acA	43	47	C.36	0.039162
ORF3a	34	T34T	acG	acA	3	44	AY.26	0.000085
ORF3a	34	T34T	acG	acA	30	44	P.1.14	0.001434
ORF3a	34	T34T	acG	acA	7	37	AY.98.1	0.000339
ORF3a	34	T34T	acG	acA	1	33	AY.117	0.000085
ORF3a	34	T34T	acG	acA	1	31	AY.113	0.000142
ORF3a	34	T34T	acG	acA	3	31	B.1.160	0.000094
ORF3a	34	T34T	acG	acA	25	30	B.1.596	0.002178
ORF3a	34	T34T	acG	acA	1	29	B.1.177.81	0.000189
ORF3a	34	T34T	acG	acA	3	28	AY.20	0.000117
ORF3a	34	T34T	acG	acA	3	28	B.1.1.33	0.001263
ORF3a	34	T34T	acG	acA	1	25	AY.42	0.00004
ORF3a	34	T34T	acG	acA	2	23	AY.6	0.000082
ORF3a	34	T34T	acG	acA	15	22	B.1.36	0.002189
ORF3a	34	T34T	acG	acA	4	21	B.1.621	0.000354
ORF3a	34	T34T	acG	acA	4	20	B.1.526	0.000094
ORF3a	34	T34T	acG	acA	8	19	AY.33	0.000534
ORF3a	34	T34T	acG	acA	1	18	B.1.466.2	0.000391
ORF3a	34	T34T	acG	acA	2	17	B.1.351	0.000059
ORF3a	34	T34T	acG	acA	11	16	AY.29	0.000174
ORF3a	34	T34T	acG	acA	1	14	AY.98	0.000079
ORF3a	34	T34T	acG	acA	6	13	AY.47	0.000187
ORF3a	34	T34T	acG	acA	2	13	B.1.1.214	0.000111
ORF3a	34	T34T	acG	acA	8	13	B.1.243	0.000557
ORF3a	34	T34T	acG	acA	1	12	C.37	0.000116
ORF3a	34	T34T	acG	acA	1	10	B	0.000128
ORF3a	34	T34T	acG	acA	10	10	B.1.637	0.000731
ORF3a	34	T34T	acG	acA	3	8	AY.23	0.000209
ORF3a	34	T34T	acG	acA	1	8	AY.45	0.000122
ORF3a	34	T34T	acG	acA	8	8	B.1.1.398	0.025806
ORF3a	34	T34T	acG	acA	1	7	AY.118	0.000063
ORF3a	34	T34T	acG	acA	2	7	AY.99.2	0.000184
ORF3a	34	T34T	acG	acA	2	7	B.1.351.2	0.000605
ORF3a	34	T34T	acG	acA	1	6	AY.54	0.000095
ORF3a	34	T34T	acG	acA	1	6	AY.9.2	0.000037
ORF3a	34	T34T	acG	acA	3	5	B.1.1.311	0.001074
ORF3a	34	T34T	acG	acA	5	5	B.1.1.523	0.007812
ORF3a	34	T34T	acG	acA	5	5	B.1.366	0.02439
ORF3a	34	T34T	acG	acA	4	5	B.1.438.1	0.000429
ORF3a	34	T34T	acG	acA	1	4	B.1.1.63	0.000386
ORF3a	34	T34T	acG	acA	4	4	B.1.595	0.001044
ORF3a	34	T34T	acG	acA	1	4	P.1.1	0.000318
ORF3a	34	T34T	acG	acA	4	4	P.1.2	0.004624
ORF3a	34	T34T	acG	acA	1	3	AY.108	0.001103
ORF3a	34	T34T	acG	acA	1	3	AY.111	0.000183
ORF3a	34	T34T	acG	acA	1	3	AY.29.1	0.000221
ORF3a	34	T34T	acG	acA	2	3	B.1.1.1	0.000653
ORF3a	34	T34T	acG	acA	3	3	P.1.10	0.000808
ORF3a	34	T34T	acG	acA	2	2		0.111111
ORF3a	34	T34T	acG	acA	1	2	AY.109	0.00074
ORF3a	34	T34T	acG	acA	1	2	AY.78	0.001541
ORF3a	34	T34T	acG	acA	2	2	B.1.1.263	0.003115
ORF3a	34	T34T	acG	acA	1	2	B.1.1.291	0.000742
ORF3a	34	T34T	acG	acA	1	2	B.1.497	0.000315
ORF3a	34	T34T	acG	acA	2	2	B.1.546	0.007407
ORF3a	34	T34T	acG	acA	2	2	B.1.568	0.002222
ORF3a	34	T34T	acG	acA	1	2	B.1.628	0.000352
ORF3a	34	T34T	acG	acA	1	1	AY.120.1	0.000321
ORF3a	34	T34T	acG	acA	1	1	AY.39.1	0.00004
ORF3a	34	T34T	acG	acA	1	1	AY.4.2.1	0.000149
ORF3a	34	T34T	acG	acA	1	1	B.1.1.50	0.000679
ORF3a	34	T34T	acG	acA	1	1	B.1.177.12	0.000152
ORF3a	34	T34T	acG	acA	1	1	B.1.177.43	0.001477
ORF3a	34	T34T	acG	acA	1	1	B.1.177.8	0.000752
ORF3a	34	T34T	acG	acA	1	1	B.1.356	0.001727
ORF3a	34	T34T	acG	acA	1	1	D.5	0.004975
ORF3a	34	T34T	acG	acA	1	1	P.1.7	0.000319
ORF3a	34	T34T	acG	acA	1	1	Q.3	0.000145
ORF3a	34	T34T	acG	acA	1	1	Q.8	0.000165

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.